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1. 发明授权

US5446749A Diode pumped, multi axial mode, intracavity doubled laser 失效
标题翻译：二极管泵浦，多轴模式，腔内双激光
公开(公告)号：US5446749A
公开(公告)日：1995-08-29
申请号：US191656
申请日：1994-02-04
申请人： William L. Nighan, Jr. , John Cole , Thomas M. Baer
发明人： William L. Nighan, Jr. , John Cole , Thomas M. Baer
IPC分类号： G02F1/35 , G02F1/37 , H01S3/081 , H01S3/094 , H01S3/0941 , H01S3/109 , H01S3/13 , H01S3/16 , H01S3/10
CPC分类号： G02F1/37 , H01S3/109 , G02F2001/3542 , H01S3/081 , H01S3/094053 , H01S3/0941 , H01S3/09415 , H01S3/13 , H01S3/1611 , H01S3/1653
摘要： A diode pumped, multiaxial mode, intracavity frequency doubled laser resonator has high amplitude stability, meaning that the percent root mean square noise (% RMS) of the doubled output beam power is low. A diode pump source supplies a pump beam to a laser crystal positioned in a resonator cavity and produces a multiaxial mode infrared beam that is incident on a doubling crystal, also positioned in the resonator. A frequency doubled output beam is produced that has an RMS of less than 3%. The laser is highly efficient, provides high output power and its output beam is of high spatial quality.
摘要翻译：二极管泵浦，多轴模式，腔内倍频激光谐振器具有高振幅稳定性，意味着双倍输出光束功率的均方根噪声百分比（％RMS）低。二极管泵浦源将泵浦光束提供给位于谐振器腔中的激光晶体，并产生入射在双晶晶体上并且位于谐振器中的多轴模式红外光束。产生频率倍增的输出光束，其RMS小于3％。激光器高效，提供高输出功率，其输出光束具有高空间质量。

2. 发明授权

US06931037B2 Diode pumped, multi axial mode intracavity doubled laser 失效
标题翻译：二极管泵浦，多轴模式腔内双激光
公开(公告)号：US06931037B2
公开(公告)日：2005-08-16
申请号：US09872865
申请日：2001-06-01
申请人： William L. Nighan, Jr. , John Cole
发明人： William L. Nighan, Jr. , John Cole
IPC分类号： G02F1/35 , G02F1/37 , H01S3/081 , H01S3/0941 , H01S3/109 , H01S3/13 , H01S3/16 , H01S3/10 , H01S3/08 , H01S3/09 , H01S3/14
CPC分类号： G02F1/37 , G02F2001/3542 , H01S3/081 , H01S3/094053 , H01S3/09415 , H01S3/109 , H01S3/13 , H01S3/1611 , H01S3/1643 , H01S3/1653 , H01S3/1673
摘要： A diode pumped, multi axial mode, intracavity doubled, intracavity tripled laser, includes at least two resonator mirrors defining a resonator cavity. A laser crystal and a doubling crystal are positioned in the resonator cavity. A tripling crystal is also positioned in the resonator cavity. A diode pump source supplies a pump beam to the laser crystal and produces a laser crystal beam with a plurality of axial modes that are incident on the doubling crystal. This produces a frequency doubled output beam. Further, a diode pumped, multi axial mode, intracavity nonlinearly-converted laser is provided and includes at least two resonator mirrors defining a resonator cavity, a laser crystal and a nonlinear conversion apparatus positioned in the resonator cavity. A nonlinear conversion apparatus is also positioned in the resonator cavity. A diode pump source supplying a pump beam to the laser crystal and produces a laser crystal beam with a plurality of axial modes that are incident on the nonlinear conversion apparatus. The result is a nonlinearly converted output beam that has a % RMS noise of less than 3%.
摘要翻译：二极管泵浦，多轴模式，腔内倍增，腔内三倍激光器包括限定谐振腔的至少两个谐振器镜。激光晶体和双晶晶体位于谐振腔中。三重晶体也位于谐振腔中。二极管泵浦源将泵浦光束提供给激光晶体，并产生具有多个入射在双晶体上的轴向模式的激光晶体束。这产生了倍频输出光束。此外，提供二极管泵浦，多轴模式，腔内非线性转换激光器，并且包括定义谐振腔的至少两个谐振器镜，激光晶体和位于谐振腔中的非线性转换装置。非线性转换装置也位于谐振器腔中。二极管泵浦源将激光束提供给激光晶体，并产生具有入射在非线性转换装置上的多个轴向模式的激光晶体光束。结果是具有小于3％的％RMS噪声的非线性转换输出光束。

3. 发明授权

US06241720B1 Diode pumped, multi axial mode intracavity doubled laser 失效
标题翻译：二极管泵浦，多轴模式腔内双激光
公开(公告)号：US06241720B1
公开(公告)日：2001-06-05
申请号：US08446203
申请日：1995-05-19
申请人： William L. Nighan, Jr. , John Cole
发明人： William L. Nighan, Jr. , John Cole
IPC分类号： A61B1818
CPC分类号： A61F9/008 , G02F1/37 , G02F2001/3542 , H01S3/081 , H01S3/094053 , H01S3/09415 , H01S3/109 , H01S3/13 , H01S3/1611 , H01S3/1643 , H01S3/1653 , H01S3/1673
摘要： A diode pumped, multi axial mode, intracavity doubled, intracavity tripled laser, includes at least two resonator mirrors defining a resonator cavity. A laser crystal and a doubling crystal are positioned in the resonator cavity. A tripling crystal is also positioned in the resonator cavity. A diode pump source supplies a pump beam to the laser crystal and produces a laser crystal beam with a plurality of axial modes that are incident on the doubling crystal. This produces a frequency doubled output beam. Further, a diode pumped, multi axial mode, intracavity nonlinearly-converted laser is provided and includes at least two resonator mirrors defining a resonator cavity, a laser crystal and a nonlinear conversion apparatus positioned in the resonator cavity. A nonlinear conversion apparatus is also positioned in the resonator cavity. A diode pump source supplying a pump beam to the laser crystal and produces a laser crystal beam with a plurality of axial modes that are incident on the nonlinear conversion apparatus. The result is a nonlinearly converted output beam that has a % RMS noise of less than 3%
摘要翻译：二极管泵浦，多轴模式，腔内倍增，腔内三倍激光器包括限定谐振腔的至少两个谐振器镜。激光晶体和双晶晶体位于谐振腔中。三重晶体也位于谐振腔中。二极管泵浦源将泵浦光束提供给激光晶体，并产生具有多个入射在双晶体上的轴向模式的激光晶体束。此外，提供二极管泵浦，多轴模式，腔内非线性转换激光器，并且包括定义谐振腔的至少两个谐振器镜，激光晶体和位于谐振腔中的非线性转换装置。非线性转换装置也位于谐振器腔中。二极管泵浦源将激光束提供给激光晶体，并产生具有入射在非线性转换装置上的多个轴向模式的激光晶体光束。结果是非线性转换的输出光束的RMS RMS噪声小于3％

4. 发明授权

US5991317A Retinal photocoagulator including diode pumped, multi-axial mode intracavity doubled laser 失效
标题翻译：视网膜光凝器包括二极管泵浦，多轴模式腔内双激光
公开(公告)号：US5991317A
公开(公告)日：1999-11-23
申请号：US35680
申请日：1998-03-05
申请人： William L. Nighan, Jr. , John Cole
发明人： William L. Nighan, Jr. , John Cole
IPC分类号： A61F9/008 , G02F1/35 , G02F1/37 , H01S3/081 , H01S3/094 , H01S3/0941 , H01S3/109 , H01S3/13 , H01S3/16 , H01S3/10
CPC分类号： A61F9/008 , G02F1/37 , H01S3/109 , G02F2001/3542 , H01S3/081 , H01S3/094053 , H01S3/09415 , H01S3/13 , H01S3/1611 , H01S3/1643 , H01S3/1653 , H01S3/1673
摘要： A diode pumped, multi axial mode, intracavity doubled, intracavity tripled laser, includes at least two resonator mirrors defining a resonator cavity. A laser crystal and a doubling crystal are positioned in the resonator cavity. A tripling crystal is also positioned in the resonator cavity. A diode pump source supplies a pump beam to the laser crystal and produces a laser crystal beam with a plurality of axial modes that are incident on the doubling crystal. This produces a frequency doubled output beam.Further, a diode pumped, multi axial mode, intracavity nonlinearly-converted laser is provided and includes at least two resonator mirrors defining a resonator cavity, a laser crystal and a nonlinear conversion apparatus positioned in the resonator cavity. A nonlinear conversion apparatus is also positioned in the resonator cavity. A diode pump source supplying a pump beam to the laser crystal and produces a laser crystal beam with a plurality of axial modes that are incident on the nonlinear conversion apparatus. The result is a nonlinearly converted output beam that has a % RMS noise of less than 3%.
摘要翻译：二极管泵浦，多轴模式，腔内倍增，腔内三倍激光器包括限定谐振腔的至少两个谐振器镜。激光晶体和双晶晶体位于谐振腔中。三重晶体也位于谐振腔中。二极管泵浦源将泵浦光束提供给激光晶体，并产生具有多个入射在双晶体上的轴向模式的激光晶体束。这产生了倍频输出光束。此外，提供二极管泵浦，多轴模式，腔内非线性转换激光器，并且包括定义谐振腔的至少两个谐振器镜，激光晶体和位于谐振腔中的非线性转换装置。非线性转换装置也位于谐振器腔中。二极管泵浦源将激光束提供给激光晶体，并产生具有入射在非线性转换装置上的多个轴向模式的激光晶体光束。结果是具有小于3％的％RMS噪声的非线性转换输出光束。

5. 发明授权

US5638388A Diode pumped, multi axial mode intracavity doubled laser 失效
标题翻译：二极管泵浦，多轴模式腔内双激光
公开(公告)号：US5638388A
公开(公告)日：1997-06-10
申请号：US446195
申请日：1995-05-19
申请人： William L. Nighan, Jr. , John Cole
发明人： William L. Nighan, Jr. , John Cole
IPC分类号： H01S3/094 , H01S3/081 , H01S3/0941 , H01S3/109 , H01S3/13 , H01S3/16 , H01J3/10
CPC分类号： H01S3/109 , H01S3/081 , H01S3/094053 , H01S3/09415 , H01S3/13 , H01S3/1611 , H01S3/1643 , H01S3/1653 , H01S3/1673
摘要： A diode pumped, multiaxial mode, intracavity frequency doubled laser resonator has high amplitude stability, meaning that the percent root mean square noise (%RMS) of the doubled output beam power is low. A diode pump source supplies a pump beam to a laser crystal positioned in a resonator cavity and produces a multiaxial mode infrared beam that is incident on a doubling crystal, also positioned in the resonator. A frequency doubled output beam is produced that has an RMS of less than 3%, and in some cases less than 0.2%. The laser is highly efficient, provides high output power, and its output beam is of high spatial quality.
摘要翻译：二极管泵浦，多轴模式，腔内倍频激光谐振器具有高振幅稳定性，意味着双倍输出光束功率的均方根噪声百分比（％RMS）低。二极管泵浦源将泵浦光束提供给位于谐振器腔中的激光晶体，并产生入射在双晶晶体上并且位于谐振器中的多轴模式红外光束。产生频率倍增的输出光束，其RMS小于3％，在某些情况下小于0.2％。激光器高效，提供高输出功率，其输出光束具有高空间质量。

6. 发明申请

US20140279237A1 System and Method for Facilitating Consumer Association with Transaction Agent 审中-公开
标题翻译：促进消费者与交易代理协会的系统和方法
公开(公告)号：US20140279237A1
公开(公告)日：2014-09-18
申请号：US13840456
申请日：2013-03-15
申请人： John Cole , Mete Kamil , Ron Litzenberger , Adam Campbell
发明人： John Cole , Mete Kamil , Ron Litzenberger , Adam Campbell
IPC分类号： G06Q30/06 , G06Q50/16
CPC分类号： G06Q30/0617 , G06Q50/16
摘要： A system for facilitating association of a consumer with a transaction agent includes a database server accessible over a communications network and configured to store data comprising either of a buyer lead pool, and selling agent lead pool. The database server is accessible by an application server having a web application that allows a consumer to indicate whether the consumer is interested in buying a property or in selling property. In the former case, the system sends a message to the listing agency whereupon the listing agent may access, or “claim,” the buyer's data, and allows non-listing agents to claim the data if the listing agent declines. In case the consumer desires to sell property, the system notifies all agents within the relevant geographic area corresponding to the property and allows a consumer to interview candidate agents.
摘要翻译：用于促进消费者与交易代理的关联的系统包括可通过通信网络访问的数据库服务器，并且被配置为存储包括买方潜水池和销售代理潜水池之一的数据。数据库服务器可以由具有允许消费者指示消费者是否有兴趣购买财产或销售财产的Web应用的应用服务器访问。在前一种情况下，系统向列出代理机构发送一个消息，上市代理可以访问上市代理人，或者“声明”买方的数据，并允许非上市代理人在上市代理拒绝时要求数据。如果消费者希望出售物业，系统会通知与该物业相对应的相关地理区域内的所有代理人，并允许消费者面试候选人。

7. 发明授权

US07722506B2 Exercise device 有权
标题翻译：运动装置
公开(公告)号：US07722506B2
公开(公告)日：2010-05-25
申请号：US12075322
申请日：2008-03-10
申请人： David C. Pratson , Axel Mnich , Tien Le , John Cole
发明人： David C. Pratson , Axel Mnich , Tien Le , John Cole
IPC分类号： A63B22/04
CPC分类号： A63B23/0458 , A63B21/068 , A63B22/18 , A63B71/0009 , A63B71/0054 , A63B2022/0033 , A63B2208/12 , A63B2225/62
摘要： An exercise for step aerobics, games, and proprioceptive input training. The device features a rigid platform supported by a resilient inflated tubular sidewall. The sidewall may be of a single tube or a plurality of tubular members engaged on top of each other. Inflation pressure of said sidewall provides an adjustment of the resilience thereby adjusting instability of the platform in the horizontal and vertical directions. Instability in the vertical direction provides a cushioning to users in a step aerobics exercise while instability in both direction provides a manner for a user moving or exercising on the platform to obtain proprioceptive input training.
摘要翻译：进行有氧运动，游戏和本体感觉输入训练的练习。该装置具有由弹性膨胀的管状侧壁支撑的刚性平台。侧壁可以是单个管或彼此顶部接合的多个管状构件。所述侧壁的充气压力提供弹性的调节，从而调节平台在水平和垂直方向上的不稳定性。在垂直方向上的不稳定性提供了用户在步进有氧运动中的缓冲，而两个方向上的不稳定性提供了用户在平台上移动或锻炼以获得本体感觉输入训练的方式。

8. 发明申请

US20070213741A1 FOLLICULAR EXTRACTION PUNCH AND METHOD 审中-公开
公开(公告)号：US20070213741A1
公开(公告)日：2007-09-13
申请号：US11565553
申请日：2006-11-30
申请人： John Cole
发明人： John Cole
IPC分类号： A61B17/50
CPC分类号： A61B17/32053 , A61B17/322 , A61B17/3403 , A61B17/3468 , A61B17/3496 , A61B2017/00752 , A61B2017/00902 , A61B2017/00969 , A61B2017/320064 , A61B2017/3492 , A61B2090/036 , A61B2090/062
摘要： Provided herein is an instrument and method useful to incise in to the skin to a precise depth and at a specific angle with respect to the surface of the skin of a patient, for the extraction of individual follicular groups or individual follicular units. An instrument according to the invention precisely limits the depth of incision, and creates a circular incision around a hair, follicular unit, or follicular cluster in a manner such that no damage occurs to any of the hair shafts.

9. 发明申请

US20070140798A1 Gear milling tool with replaceable cutting inserts 有权
标题翻译：带可更换切削刀片的齿轮铣刀
公开(公告)号：US20070140798A1
公开(公告)日：2007-06-21
申请号：US11305467
申请日：2005-12-16
申请人： Larry Cole , John Cole , Robert Kranker
发明人： Larry Cole , John Cole , Robert Kranker
IPC分类号： B23F21/22
CPC分类号： B23F21/226 , B23C5/2221 , B23C5/223 , B23C2200/0416 , Y10T407/1705 , Y10T407/191 , Y10T407/22 , Y10T407/2202 , Y10T407/23
摘要： A cutting tool assembly adapted to be coupled to a cutter head for manufacture of a gear. The cutting tool assembly includes a cutting insert and a holder adapted to couple the cutting insert to the cutting head. The holder includes a pocket defined by a back surface and at least one lip member that provides a force directed against the cutting insert toward the back surface to thereby retain the cutting insert within the pocket during cutting operations.
摘要翻译：一种切割工具组件，其适于联接到用于制造齿轮的切割头。切割工具组件包括切削刀片和适于将切削刀片连接到切割头的保持器。保持器包括由后表面限定的凹部和至少一个唇形构件，其在切割操作期间向切削刀片提供朝向后表面的力，从而将切削刀片保持在凹槽内。

10. 发明申请

US20070099223A1 Single nucleotide polymorphism associated with stroke susceptibility 审中-公开
标题翻译：与卒中易感性相关的单核苷酸多态性
公开(公告)号：US20070099223A1
公开(公告)日：2007-05-03
申请号：US11589487
申请日：2006-10-30
申请人： Steven Kittner , Qing Song , Braxton Mitchell , Jeffrey O'Connell , John Cole , O. Stine , Gary Gibbons
发明人： Steven Kittner , Qing Song , Braxton Mitchell , Jeffrey O'Connell , John Cole , O. Stine , Gary Gibbons
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/112 , C12Q2600/156 , C12Q2600/172
摘要： The present invention identifies various risk alleles, particularly a risk allele of SNP rs918592, within the PDE4D gene as novel stroke associated risk markers. These markers may be used for identifying a subject's susceptibility to stroke and diagnosing a subject's susceptibility to a particular type of stroke based on the presence of the risk allele. The markers are found in the human population, particularly the human female population, across different ethnicities. The marker further reveals an environmental impact on a subject's susceptibility to stroke, showing a dose dependent relationship.
摘要翻译：本发明将PDE4D基因内的各种风险等位基因，特别是SNP rs918592的风险等位基因鉴定为新的中风相关风险标记。这些标记物可以用于鉴定受试者对中风的易感性并且基于风险等位基因的存在来诊断受试者对特定类型中风的易感性。标记在人群中，特别是在不同种族的人类女性人群中发现。标记进一步揭示了对受试者对中风的易感性的环境影响，显示出剂量依赖关系。

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