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1. 发明申请

US20080305328A1 Laser-Imageable Marking Compositions 有权
标题翻译：激光成像标记组合
公开(公告)号：US20080305328A1
公开(公告)日：2008-12-11
申请号：US12095414
申请日：2006-12-04
申请人： William Green , Tristan Phillips , Anthony Jarvis , Christopher Anthony Wyres , Trevor Wilson
发明人： William Green , Tristan Phillips , Anthony Jarvis , Christopher Anthony Wyres , Trevor Wilson
IPC分类号： B32B7/10 , B05D3/06
CPC分类号： B41M5/267 , B41M5/283 , B41M5/284 , B41M5/30 , B41M5/46 , Y10T428/28 , Y10T428/2848
摘要： A tape construct comprises a laser-imageable composition, whereby images can be created in said tape by irradiation with a laser. In an alternative, a laser-imageable formulation suitable for spray application to a substrate, comprises a colour-former, a binder and a carrier.
摘要翻译：胶带构造包括可激光成像的组合物，由此可以通过用激光照射在所述带中形成图像。替代地，适用于喷涂在基材上的可激光成像制剂包括成色剂，粘合剂和载体。

2. 发明授权

US08173253B2 Laser-imageable marking compositions 有权
标题翻译：可激光标记组合物
公开(公告)号：US08173253B2
公开(公告)日：2012-05-08
申请号：US12095414
申请日：2006-12-04
申请人： William Green , Tristan Phillips , Anthony Jarvis , Christopher Anthony Wyres , Trevor Wilson
发明人： William Green , Tristan Phillips , Anthony Jarvis , Christopher Anthony Wyres , Trevor Wilson
IPC分类号： B32B7/12 , C08J7/18
CPC分类号： B41M5/267 , B41M5/283 , B41M5/284 , B41M5/30 , B41M5/46 , Y10T428/28 , Y10T428/2848
摘要： A tape construct comprises a laser-imageable composition, whereby images can be created in said tape by irradiation with a laser. In an alternative, a laser-imageable formulation suitable for spray application to a substrate, comprises a color-former, a binder and a carrier.
摘要翻译：胶带构造包括可激光成像的组合物，由此可以通过用激光照射在所述带中形成图像。替代地，适用于喷涂在基材上的可激光成像制剂包括成色剂，粘合剂和载体。

3. 发明申请

US20060264434A1 Chemokine receptor binding heterocyclic compounds 失效
公开(公告)号：US20060264434A1
公开(公告)日：2006-11-23
申请号：US11494943
申请日：2006-07-27
申请人： Gary Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols
发明人： Gary Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols
IPC分类号： A61K31/5377 , A61K31/4545 , A61K31/4439 , C07D401/02 , C07D413/02
CPC分类号： C07D239/42 , A61K45/06 , C07D213/38 , C07D215/40 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D451/04 , C07D471/04 , C07D487/04
摘要： This invention relates to a novel class of heterocyclic compounds that bind chemokine receptors, inhibiting the binding of their natural ligands thereby. These compounds result in protective effects against infection by HIV through binding to chemokine receptors, including CXCR4 and CCR5, thus inhibiting the subsequent binding by these chemokines. The present invention provides a compound of Formula I wherein, W is a nitrogen atom and Y is absent or, W is a carbon atom and Y=H; R1 to R7 may be the same or different and are independently selected from hydrogen or straight, branched or cyclic C1-6 alkyl; R8 is a substituted heterocyclic group or a substituted aromatic group Ar is an aromatic or heteroaromatic ring each optionally substituted at single or multiple, non-linking positions with electron-donating or withdrawing groups; n and n′ are independently, 0-2; X is a group of the formula: Wherein, Ring A is an optionally substituted, saturated or unsaturated 5 or 6-membered ring, and P is an optionally substituted carbon atom, an optionally substituted nitrogen atom, sulfur or oxygen atom. Ring B is an optionally substituted 5 to 7-membered ring. Ring A and Ring B in the above formula can be connected to the group W from any position via the group V, wherein V is a chemical bond, a (CH2)n″ group (where n″=0-2) or a C═O group. Z is, (1) a hydrogen atom, (2) an optionally substituted C1-6 alkyl group, (3) a C0-6 alkyl group substituted with an optionally substituted aromatic or heterocyclic group, (4) an optionally substituted C0-6 alkylamino or C3-7 cycloalkylamino group, (5) an optionally substituted carbonyl group or sulfonyl. These compounds further include any pharmaceutically acceptable acid addition salts and metal complexes thereof and any stereoisomeric forms and mixtures of stereoisomeric forms thereof.

4. 发明申请

US20060128750A1 Chemokine receptor binding heterocyclic compounds 失效
标题翻译：趋化因子受体结合杂环化合物
公开(公告)号：US20060128750A1
公开(公告)日：2006-06-15
申请号：US11345987
申请日：2006-02-02
申请人： Gary Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols , Christopher Smith , Maria Di Fluri
发明人： Gary Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols , Christopher Smith , Maria Di Fluri
IPC分类号： C07D401/14 , A61K31/4709
CPC分类号： C07D401/14 , C07D213/38 , C07D213/65 , C07D401/12 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D493/04
摘要： Tertiary amine compounds that bind chemokine receptors such as CXCR4 and CCR5 are disclosed.
摘要翻译：公开了结合趋化因子受体如CXCR4和CCR5的叔胺化合物。

5. 发明申请

US20070142095A1 CAR TELEPHONE SYSTEM 有权
标题翻译：汽车电话系统
公开(公告)号：US20070142095A1
公开(公告)日：2007-06-21
申请号：US11425178
申请日：2006-06-20
申请人： Eckhard Bollmann , Trevor Wilson
发明人： Eckhard Bollmann , Trevor Wilson
IPC分类号： H04M1/00
CPC分类号： H04M1/6091
摘要： A car telephone system having a telephone module (3) which has a telephone transmitting and receiving unit (5), can be connected to a transmitting and receiving antenna (7), can be connected to a central control bus (1) of the vehicle and can be controlled by a central controller (2) via the control bus (1) enables telephone operation, via the telephone module (3), using user-specific data from a mobile telephone (9) by virtue of the fact that the telephone transmitting and receiving unit (5) is provided with a wireless data and signal transmission unit (6) which can be used to transmit user-specific data from a mobile telephone (9) to the telephone transmitting and receiving unit (5), and by virtue of the fact that the telephone transmitting and receiving unit (5) is also connected to a separate card reader (11) for a memory card which contains the user-specific data from the mobile telephone (9).
摘要翻译：具有具有电话发送和接收单元（5）的电话模块（3）的汽车电话系统可以连接到发送和接收天线（7），可以连接到车辆的中央控制总线（1）并且可以经由控制总线（1）由中央控制器（2）控制，使得经由电话模块（3）的电话操作可以利用来自移动电话（9）的用户特定数据，凭借电话发送和接收单元（5）设置有无线数据和信号传输单元（6），其可以用于将用户特定的数据从移动电话（9）发送到电话发送和接收单元（5），并且通过凭借电话发送和接收单元（5）也连接到包含来自移动电话（9）的用户特定数据的存储卡的单独读卡器（11）的事实。

6. 发明申请

US20050026942A1 Chemokine receptor binding heterocyclic compounds 失效
标题翻译：趋化因子受体结合杂环化合物
公开(公告)号：US20050026942A1
公开(公告)日：2005-02-03
申请号：US10914663
申请日：2004-08-09
申请人： Gary Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols , Christopher Smith , Maria Di Fluri
发明人： Gary Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols , Christopher Smith , Maria Di Fluri
IPC分类号： A61K31/444 , A61K31/4545 , A61K31/455 , A61K31/4706 , A61K31/4709 , A61K31/506 , A61P1/04 , A61P3/10 , A61P5/14 , A61P9/00 , A61P11/00 , A61P11/02 , A61P11/06 , A61P13/12 , A61P17/00 , A61P17/02 , A61P17/04 , A61P17/06 , A61P19/00 , A61P19/02 , A61P21/00 , A61P21/04 , A61P29/00 , A61P31/04 , A61P31/12 , A61P31/18 , A61P31/22 , A61P33/00 , A61P33/02 , A61P33/06 , A61P33/10 , A61P35/00 , A61P35/02 , A61P37/00 , A61P37/02 , A61P37/08 , A61P43/00 , C07D213/81 , C07D215/40 , C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D491/04 , C07D491/052 , C07D471/02 , A61K31/47 , C07D491/02 , C07D498/02
CPC分类号： C07D213/38 , C07D213/65 , C07D213/81 , C07D215/40 , C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D491/04
摘要： Tertiary amines containing a multiplicity of heteroaromatic substituents are useful as chemokine receptor modulators.
摘要翻译：含有多个杂芳族取代基的叔胺可用作趋化因子受体调节剂。

7. 发明授权

US07702312B2 Car telephone system 有权
标题翻译：汽车电话系统
公开(公告)号：US07702312B2
公开(公告)日：2010-04-20
申请号：US11425178
申请日：2006-06-20
申请人： Eckhard Bollmann , Trevor Wilson
发明人： Eckhard Bollmann , Trevor Wilson
IPC分类号： H04M1/00
CPC分类号： H04M1/6091
摘要： A car telephone system having a telephone module (3) which has a telephone transmitting and receiving unit (5), can be connected to a transmitting and receiving antenna (7), can be connected to a central control bus (1) of the vehicle and can be controlled by a central controller (2) via the control bus (1) enables telephone operation, via the telephone module (3), using user-specific data from a mobile telephone (9) by virtue of the fact that the telephone transmitting and receiving unit (5) is provided with a wireless data and signal transmission unit (6) which can be used to transmit user-specific data from a mobile telephone (9) to the telephone transmitting and receiving unit (5), and by virtue of the fact that the telephone transmitting and receiving unit (5) is also connected to a separate card reader (11) for a memory card which contains the user-specific data from the mobile telephone (9).
摘要翻译：具有具有电话发送和接收单元（5）的电话模块（3）的汽车电话系统可以连接到发送和接收天线（7），可以连接到车辆的中央控制总线（1）并且可以经由控制总线（1）由中央控制器（2）控制，使得经由电话模块（3）的电话操作可以利用来自移动电话（9）的用户特定数据，凭借电话发送和接收单元（5）设置有无线数据和信号传输单元（6），其可以用于将用户特定的数据从移动电话（9）发送到电话发送和接收单元（5），并且通过凭借电话发送和接收单元（5）也连接到包含来自移动电话（9）的用户特定数据的存储卡的单独读卡器（11）的事实。

8. 发明申请

US20080090846A1 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS 审中-公开
标题翻译：化合物受体结合杂环化合物
公开(公告)号：US20080090846A1
公开(公告)日：2008-04-17
申请号：US11956190
申请日：2007-12-13
申请人： Gary Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols , Christopher Smith , Rosaria Di Fluri
发明人： Gary Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols , Christopher Smith , Rosaria Di Fluri
IPC分类号： A61K31/436 , A61K31/47 , A61K31/506 , C07D215/38 , C07D401/14 , C07D491/052
CPC分类号： C07D213/38 , C07D213/65 , C07D213/81 , C07D215/40 , C07D401/12 , C07D401/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D491/04
摘要： Tertiary amines containing a multiplicity of heteroaromatic substituents are useful as chemokine receptor modulators.
摘要翻译：含有多个杂芳族取代基的叔胺可用作趋化因子受体调节剂。

9. 发明申请

US20060252795A1 Chemokine receptor binding heterocyclic compounds 失效
公开(公告)号：US20060252795A1
公开(公告)日：2006-11-09
申请号：US11487038
申请日：2006-07-14
申请人： Gary Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols , Christopher Smith , Maria Di Fluri
发明人： Gary Bridger , Renato Skerlj , Al Kaller , Curtis Harwig , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols , Christopher Smith , Maria Di Fluri
IPC分类号： A61K31/4709
CPC分类号： C07D213/81 , A61K31/4709 , C07D213/38 , C07D213/65 , C07D215/40 , C07D231/12 , C07D233/56 , C07D249/08 , C07D401/12 , C07D401/14 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D491/04 , C07D493/04 , Y02A50/411
摘要： Compounds which modulate chemokine receptor activities are disclosed. These compounds are preferably tertiary amines comprising tetrahydroquinoline and benzimidazole.

10. 发明申请

US20060100240A1 Chemokine receptor binding heterocyclic compounds with enhanced efficacy 有权
公开(公告)号：US20060100240A1
公开(公告)日：2006-05-11
申请号：US11301725
申请日：2005-12-13
申请人： Gary Bridger , Ai Kaller , Curtis Harwig , Renato Skerlj , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols , Christopher Smith , Maria Di Fluri
发明人： Gary Bridger , Ai Kaller , Curtis Harwig , Renato Skerlj , David Bogucki , Trevor Wilson , Jason Crawford , Ernest McEachern , Bem Atsma , Siqiao Nan , Yuanxi Zhou , Dominique Schols , Christopher Smith , Maria Di Fluri
IPC分类号： A61K31/4709 , C07D403/02 , C07D403/14
CPC分类号： C07D401/14 , C07D235/14 , C07D401/12 , C07D403/12 , C07D471/04 , C07D471/06 , C07D491/04
摘要： The invention relates to heterocyclic compounds consisting of a core nitrogen atom surrounded by three pendant groups, wherein two of the three pendant groups are preferably benzimidazolyl methyl and tetrahydroquinolyl, and the third pendant group contains N and optionally contains additional rings. The compounds bind to chemokine receptors, including CXCR4 and CCR5, and demonstrate protective effects against infection of target cells by a human immunodeficiency virus (HIV).

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