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1. 发明授权

US4650892A Process for the preparation of herbicidal sulfonamides 失效
标题翻译：制备除草磺酰胺的方法
公开(公告)号：US4650892A
公开(公告)日：1987-03-17
申请号：US812613
申请日：1985-12-23
申请人： William A. Kleschick , Anna P. Vinogradoff , Joseph E. Dunbar
发明人： William A. Kleschick , Anna P. Vinogradoff , Joseph E. Dunbar
IPC分类号： C07D249/14 , C07D409/12 , C07D487/04 , C07D487/00 , C07C157/14 , C07D239/00
CPC分类号： C07D409/12 , C07D249/14 , C07D487/04
摘要： Sulfonamides derived from substituted 2-amino-1,2,4-triazolo[1,5-a]pyrimidines are prepared by reacting a desired sulfonamide with dimethyl N-cyanodithioiminocarbonate in the presence of a base followed by reaction with an excess of hydrazine and then a 1,3-dicarbonyl compound.The resulting products have a variety of herbicidal uses.
摘要翻译：衍生自取代的2-氨基-1,2,4-三唑并[1,5-a]嘧啶的磺酰胺通过使所需的磺酰胺与N-二氰基二硫代亚氨基碳酸二甲酯在碱的存在下反应，然后与过量的肼反应，然后是1,3-二羰基化合物。所得产品具有各种除草用途。

2. 发明授权

US4638075A Herbicidal sulfonamides 失效
标题翻译：除草磺酰胺
公开(公告)号：US4638075A
公开(公告)日：1987-01-20
申请号：US812612
申请日：1985-12-23
申请人： William A. Kleschick , Anna P. Vinogradoff , Joseph E. Dunbar
发明人： William A. Kleschick , Anna P. Vinogradoff , Joseph E. Dunbar
IPC分类号： C07D249/14 , C07D409/12 , C07D487/04 , C07C157/14 , C07D333/32 , C07D333/38 , C07D487/00
CPC分类号： C07D409/12 , C07D249/14 , C07D487/04
摘要： Sulfonamides derived from substituted 2-amino-1,2,4-triazolo[1,5-a]pyrimidines are prepared by reacting a desired sulfonamide with dimethyl N-cyanodithioiminocarbonate in the presence of a base followed by reaction with an excess of hydrazine and then a 1,3-dicarbonyl compound.The resulting products have a variety of herbicidal uses.
摘要翻译：衍生自取代的2-氨基-1,2,4-三唑并[1,5-a]嘧啶的磺酰胺通过使所需的磺酰胺与N-二氰基二硫代亚氨基碳酸二甲酯在碱的存在下反应，然后与过量的肼反应，然后是1,3-二羰基化合物。所得产品具有各种除草用途。

3. 发明授权

US4772720A Process for the preparation of intermediates useful for making herbicidal sulfonamides derived from substituted 2-amino-1,2,4-triazolo(1,5-A)pyrimidines 失效
标题翻译：制备用于制备衍生自取代的2-氨基-1,2,4-三唑并（1,5-A）嘧啶的除草磺酰胺的中间体的方法
公开(公告)号：US4772720A
公开(公告)日：1988-09-20
申请号：US894427
申请日：1986-08-08
申请人： William A. Kleschick , Anna P. Vinogradoff , Joseph E. Dunbar
发明人： William A. Kleschick , Anna P. Vinogradoff , Joseph E. Dunbar
IPC分类号： C07D249/14 , C07D409/12 , C07D487/04
CPC分类号： C07D409/12 , C07D249/14 , C07D487/04
摘要： Sulfonamides derived from substituted 2-amino-1,2,4-triazolo[1,5-a]pyrimidines are prepared by reacting a desired sulfonamide with dimethyl N-cyanodithioiminocarbonate in the presence of a base followed by reaction with an excess of hydrazine and then a 1,3-dicarbonyl compound.The resulting products have a variety of herbicidal uses.
摘要翻译：衍生自取代的2-氨基-1,2,4-三唑并[1,5-a]嘧啶的磺酰胺通过使所需的磺酰胺与N-二氰基二硫代亚氨基碳酸二甲酯在碱的存在下反应，然后与过量的肼反应，然后是1,3-二羰基化合物。所得产品具有各种除草用途。

4. 发明授权

US5032301A High performance lubricants comprising triazine derivatives 失效
标题翻译：包含三嗪衍生物的高性能润滑剂
公开(公告)号：US5032301A
公开(公告)日：1991-07-16
申请号：US505820
申请日：1990-04-06
申请人： Chester E. Pawloski , Joseph E. Dunbar , Muthiah N. Inbasekaran
发明人： Chester E. Pawloski , Joseph E. Dunbar , Muthiah N. Inbasekaran
IPC分类号： C07D251/20 , C07D251/24 , C10M105/70 , C10M133/42
CPC分类号： C10M133/42 , C07D251/20 , C07D251/24 , C10M105/70 , C10M2215/222
摘要： Triazines substituted with at least one aryloxy perfluoroisopropyl moiety are disclosed. These compounds, either alone or as additives, are useful as high temperature lubricants.
摘要翻译：公开了被至少一个芳氧基全氟异丙基部分取代的三嗪。这些化合物，单独使用或作为添加剂，可用作高温润滑剂。

5. 发明授权

US4701211A Substituted benzyltriethylammonium salts and their use as plant growth enhancers 失效
标题翻译：取代的苄基三乙基铵盐及其作为植物生长增强剂的用途
公开(公告)号：US4701211A
公开(公告)日：1987-10-20
申请号：US746142
申请日：1985-06-18
申请人： Joseph E. Dunbar , Theodore W. Holmsen , Herman O. Senkbeil
发明人： Joseph E. Dunbar , Theodore W. Holmsen , Herman O. Senkbeil
IPC分类号： A01N33/12 , C07C87/30
CPC分类号： A01N33/12
摘要： Compounds are prepared which correspond to the formula ##STR1## wherein R represents hydrogen, chloro, bromo or trifluoromethyl; n represents an integer of from 1 or 2, with the proviso that when R is trifluoromethyl, n is 1; and X represents a non-phytotoxic anion. The compounds have been found to be active plant growth enhancers.
摘要翻译：制备符合下式的化合物：其中R代表氢，氯，溴或三氟甲基; n表示1或2的整数，条件是当R是三氟甲基时，n是1; X表示非植物毒性阴离子。已经发现这些化合物是活性植物生长增强剂。

6. 发明授权

US4281118A Aminoalkylsulfides, aminoalkylsulfoxides, and aminoalkylsulfones 失效
标题翻译：氨基烷基硫化物，氨基烷基亚砜和氨基烷基砜
公开(公告)号：US4281118A
公开(公告)日：1981-07-28
申请号：US49029
申请日：1979-06-18
申请人： Joseph E. Dunbar , Louis E. Begin
发明人： Joseph E. Dunbar , Louis E. Begin
IPC分类号： C07D295/092 , C07D413/12 , A61K31/445 , A61K31/535 , C07D295/08
CPC分类号： C07D295/088
摘要： Novel aminoalkylsulfides, aminoalkylsulfoxides and aminoalkylsulfones of the general formula ##STR1## wherein y and z independently represent the integer 0, 1 or 2; a represents the integer 0 or 2; n represents the integer 1, 2, 3 or 4; R.sub.1 independently represent lower alkyl or hydrogen or alternatively R.sub.1 and R.sub.2 taken together with the adjacent nitrogen atom represent a 5 or 6 membered heterocyclic ring which may optionally contain an oxygen atom whereby a morpholino, piperidino, or pyrrolidino grouping is formed; R.sub.3 represents halo such as chloro or bromo, lower alkylthio, arloweralkylthio, arylthio such as 4-methylphenylthio, 4-morpholinylloweralkylthio such as 4-morpholinylpropylthio, lower alkyl or arloweralkylamino such as 4-methoxybenzenemethanamino; R.sub.4 represents hydrogen or lower alkyl. The invention also includes the pharmaceutically-acceptable salts of the compounds described herein.
摘要翻译：新型氨基烷基硫醚，氨基烷基亚砜和通式为“IMAGE”的氨基烷基砜，其中y和z独立地表示整数0,1或2; a表示整数0或2; n表示整数1,2,3或4; R1独立地表示低级烷基或氢，或者R1和R2与相邻氮原子一起表示5或6元杂环，其可以任选地含有氧原子，由此形成吗啉代，哌啶子基或吡咯烷子基; R 3表示卤素如氯或溴，低级烷硫基，芳烷硫基，芳硫基如4-甲苯硫基，4-吗啉基低级烷硫基如4-吗啉基丙硫基，低级烷基或芳烷基氨基如4-甲氧基苯甲氨基氨基; R4代表氢或低级烷基。本发明还包括本文所述化合物的药学上可接受的盐。

7. 发明授权

US4134996A Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines 失效
标题翻译：使用苯乙烯胺抑制ADP诱导的平板聚集的方法
公开(公告)号：US4134996A
公开(公告)日：1979-01-16
申请号：US833125
申请日：1977-09-14
申请人： Joseph E. Dunbar , Louis E. Begin , Robert J. Broersma , George D. Dickerson
发明人： Joseph E. Dunbar , Louis E. Begin , Robert J. Broersma , George D. Dickerson
IPC分类号： C07D295/092 , A61K31/135 , A61K31/33 , A61K31/445 , A61K31/535
CPC分类号： C07D295/088 , Y10S514/822 , Y10S514/834
摘要： A method for inhibiting blood platelet aggregation in a mammal by administering internally to the mammal an effective amount of a phenylthio(sulfinyl or sulfonyl)alkylamine compound or a pharmaceutically-acceptable salt thereof.
摘要翻译：一种通过向哺乳动物内部施用有效量的苯硫基（亚磺酰基或磺酰基）烷基胺化合物或其药学上可接受的盐来抑制哺乳动物血小板聚集的方法。

8. 发明授权

US3931235A Process for preparing sulfur-containing hydroxy pyrones 失效
标题翻译：制备含硫羟基吡咯烷酮的方法
公开(公告)号：US3931235A
公开(公告)日：1976-01-06
申请号：US429313
申请日：1973-12-28
申请人： Robert F. Harris , Joseph E. Dunbar
发明人： Robert F. Harris , Joseph E. Dunbar
IPC分类号： C07D309/38
CPC分类号： C07D309/38
摘要： This invention concerns sulfur-containing hydroxy pyrones corresponding to the formula ##SPC1##Wherein M is H or alkali metal, R is methyl, R' is hydrogen, alkyl, phenyl, halophenyl, nitrophenyl, loweralkylphenyl, benzyl, phenethyl, naphthylmethyl, halobenzyl, loweralkylbenzyl, nitrobenzyl, propargyl, allyl, cyclohexyl loweralkyl, (loweralkylthio)-loweralkyl or adamantyl and n is 0 to 2. The compounds are prepared by reacting the mono-alkali metal salt of 4-hydroxy-6-methyl-2-pyrone with an appropriate thiosulfonate, advantageously in the presence of an organic solvent. The compounds have utility as plant growth stunters and as antimicrobial agents.
摘要翻译：本发明涉及对应于式WHEREIN M为H或碱金属，R为甲基，R'为氢，烷基，苯基，卤代苯基，硝基苯基，低级烷基苯基，苄基，苯乙基，萘甲基，卤代苄基，低级烷基苄基，硝基苄基，炔丙基，烯丙基，环己基低级烷基，（低级烷硫基） - 低级烷基或金刚烷基，n为0至2.通过使4-羟基-6-甲基-2-吡喃酮的单碱金属盐与适当的硫代磺酸酯有利地在有机溶剂的存在下进行。这些化合物具有作为植物生长刺激和作为抗微生物剂的作用。

9. 发明授权

US4661520A Cyanoguanidine useful as an animal growth promoting agent 失效
标题翻译：氰胍可用作动物生长促进剂
公开(公告)号：US4661520A
公开(公告)日：1987-04-28
申请号：US641809
申请日：1984-08-17
申请人： Joseph E. Dunbar , David M. Hedstrand , Kimiaki Maruyama
发明人： Joseph E. Dunbar , David M. Hedstrand , Kimiaki Maruyama
IPC分类号： A61K31/275 , A61K31/17 , C07C129/14
CPC分类号： A61K31/275
摘要： This invention relates to a novel cyanoguanidine compound, N'-cyano-N-(1,2,3,4-tetrahydro-1-naphthyl)guanidine, which is useful as an animal growth promoting agent.
摘要翻译：本发明涉及可用作动物生长促进剂的新型氰基氰化合物N'-氰基-N-（1,2,3,4-四氢-1-萘基）胍。

10. 发明授权

US4155907A Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines 失效
标题翻译：用苯硫基烷基胺抑制ADP诱导的血小板聚集的方法
公开(公告)号：US4155907A
公开(公告)日：1979-05-22
申请号：US714950
申请日：1976-08-16
申请人： Joseph E. Dunbar , Louis E. Begin , Robert J. Broersma , George D. Dickerson
发明人： Joseph E. Dunbar , Louis E. Begin , Robert J. Broersma , George D. Dickerson
IPC分类号： C07D295/092 , A61K31/535 , A61K31/165 , A61K31/195 , A61K31/22
CPC分类号： C07D295/088 , Y10S514/822 , Y10S514/834
摘要： A method for inhibiting blood platelet aggregation in a mammal by administering internally to the mammal an effective amount of a phenylthio(sulfinyl or sulfonyl)alkylamine compound or a pharmaceutically-acceptable salt thereof.
摘要翻译：一种通过向哺乳动物内部施用有效量的苯硫基（亚磺酰基或磺酰基）烷基胺化合物或其药学上可接受的盐来抑制哺乳动物血小板聚集的方法。

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