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1. 发明申请

US20120202872A1 METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND PROGNOSIS OF CERVICAL INTRAEPITHELIAL NEOPLASIA AND CERVICAL CANCER 有权
标题翻译：宫颈内膜和宫颈癌的诊断和预防的方法和组合
公开(公告)号：US20120202872A1
公开(公告)日：2012-08-09
申请号：US13389428
申请日：2010-08-06
申请人： Wenyan Qin , Peng Dong , Tuo Deng , Cailing Ma , Keith Richard Mitchelson , Hao Wen , Jing Cheng
发明人： Wenyan Qin , Peng Dong , Tuo Deng , Cailing Ma , Keith Richard Mitchelson , Hao Wen , Jing Cheng
IPC分类号： A61K31/713 , C07H21/02 , G01N33/53 , C40B40/06 , C40B30/04 , C12Q1/68 , C07H21/04 , A61P35/00
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , C12Q2600/178
摘要： The invention provides methods and compositions for the diagnosis and prognosis of cervical intraepithelial neoplasia and cervical cancer. The methods comprise the step of determining the expression levels or genetic status of specific miRNAs.
摘要翻译：本发明提供了用于宫颈上皮内瘤变和子宫颈癌的诊断和预后的方法和组合物。该方法包括确定特异性miRNA的表达水平或遗传状态的步骤。

2. 发明授权

US08957039B2 Methods and compositions for the diagnosis and prognosis of cervical intraepithelial neoplasia and cervical cancer 有权
标题翻译：宫颈上皮内瘤变和子宫颈癌的诊断和预后的方法和组成
公开(公告)号：US08957039B2
公开(公告)日：2015-02-17
申请号：US13389428
申请日：2010-08-06
申请人： Wenyan Qin , Peng Dong , Tuo Deng , Cailing Ma , Keith Richard Mitchelson , Hao Wen , Jing Cheng
发明人： Wenyan Qin , Peng Dong , Tuo Deng , Cailing Ma , Keith Richard Mitchelson , Hao Wen , Jing Cheng
IPC分类号： C12N15/11 , C40B40/06 , C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158 , C12Q2600/178
摘要： The invention provides methods and compositions for the diagnosis and prognosis of cervical intraepithelial neoplasia and cervical cancer. The methods comprise the step of determining the expression levels or genetic status of specific miRNAs.
摘要翻译：本发明提供了用于宫颈上皮内瘤变和子宫颈癌的诊断和预后的方法和组合物。该方法包括确定特异性miRNA的表达水平或遗传状态的步骤。

3. 发明授权

US08033976B2 Apparatus and method for centrifugal separation utilizing a movable collection assembly 有权
标题翻译：利用可移动收集组件进行离心分离的装置和方法
公开(公告)号：US08033976B2
公开(公告)日：2011-10-11
申请号：US10573870
申请日：2004-09-30
申请人： Keith Richard Mitchelson
发明人： Keith Richard Mitchelson
IPC分类号： B04B11/08
CPC分类号： B04B11/082 , B01D17/0217 , B01D21/2416 , B01D21/26 , B01D21/262 , B01D2221/10 , B04B1/02 , B04B5/0442 , B04B11/06 , B04B15/06
摘要： The invention provides an apparatus for separating a multiphase mixture into discrete density phases, comprising a circular bowl rotatable about a central axis and having an opening through which the mixture is introduced into the bowl, whereby the rotation of the bowl separates the mixture to form annular columns of the discrete density phases; a delivery conduit inserted into the bowl through the opening for introducing the mixture into the bowl; and a collection assembly for removing the separated discrete density phases, comprising a collection conduit for collecting the annular columns, a waste collecting conduit, and a cleaning conduit. The collection assembly is movable as a single unit with respect to the bowl such that it can be positioned within the bowl to sequentially, selectively and individually remove the annular columns from the bowl while the bowl is rotating substantially without disturbing the remaining annular columns within the bowl.
摘要翻译：本发明提供了一种用于将多相混合物分离为离散密度相的装置，包括可围绕中心轴线旋转的圆形碗，并具有开口，混合物通过该开口引入碗中，由此碗的旋转将混合物分离成环形离散密度相的列; 通过所述开口插入到所述碗中的输送导管，用于将所述混合物引入所述碗中; 以及用于去除分离的离散密度相的收集组件，包括用于收集环形柱的收集管道，废物收集管道和清洁管道。收集组件相对于碗可以作为单个单元移动，使得其可以定位在碗中以顺序地，选择性地和独立地从碗中移除环形柱，同时碗基本上旋转而不干扰在碗内的剩余环形柱碗。

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