会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 6. 发明申请
    • Vanilloid receptor ligands and their use in treatments
    • 香草素受体配体及其在治疗中的应用
    • US20050176726A1
    • 2005-08-11
    • US11056568
    • 2005-02-11
    • Hui-Ling WangChenera BalanElizabeth DohertyJames FalseyVijay GoreJodie KatonMark Norman
    • Hui-Ling WangChenera BalanElizabeth DohertyJames FalseyVijay GoreJodie KatonMark Norman
    • C07D401/12C07D403/12C07D405/12C07D413/12C07D417/12C07D417/14C07D471/04A61K31/506C07D43/14
    • C07D401/12C07D403/12C07D405/12C07D413/12C07D417/12C07D417/14C07D471/04
    • Pyrimidine ethers and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
    • 嘧啶醚和含有它们的组合物,用于治疗急性,炎性和神经性疼痛,牙痛,一般头痛,偏头痛,丛集性头痛,混合血管和非血管性综合征,紧张性头痛,一般炎症,关节炎,风湿性疾病,骨关节炎 ,炎症性肠病,炎症性眼病,炎症性或不稳定性膀胱病,银屑病,皮肤炎症成分炎症,慢性炎性病症,炎性疼痛及相关的痛觉过敏和异常性疼痛,神经性疼痛及相关的痛觉过敏和异常性疼痛,糖尿病性神经病疼痛,灼痛,交感神经痛 维持疼痛,输血综合征,哮喘,上皮组织损伤或功能障碍,单纯疱疹,呼吸系统内脏运动紊乱,泌尿生殖道,胃肠道或血管区域,伤口,烧伤,过敏性皮肤反应,瘙痒,白癜风,一般胃肠道疾病,胃溃疡, 杜 腹部溃疡,腹泻,坏死因子诱导的胃损伤,毛发生长,血管舒缩或过敏性鼻炎,支气管疾病或膀胱疾病。
    • 7. 发明申请
    • Vanilloid receptor ligands and their use in treatments
    • 香草素受体配体及其在治疗中的应用
    • US20050182067A1
    • 2005-08-18
    • US11056534
    • 2005-02-11
    • Chenera BalanNing ChenElizabeth DohertyVijay GoreMark NormanHui-Ling Wang
    • Chenera BalanNing ChenElizabeth DohertyVijay GoreMark NormanHui-Ling Wang
    • A61K31/44A61K31/444A61K31/505C07D401/12C07D401/14C07D403/12C07D403/14C07D413/12C07D417/12C07D417/14A61K31/506C07D43/14
    • C07D401/12C07D401/14C07D403/12C07D403/14C07D413/12C07D417/12C07D417/14
    • Compounds having the general structure and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritis, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
    • 具有一般结构和含有它们的组合物的化合物,用于治疗急性,炎性和神经性疼痛,牙痛,一般头痛,偏头痛,丛集性头痛,混合血管和非血管综合征,紧张性头痛,一般炎症,关节炎,风湿性 疾病,骨关节炎,炎症性肠病,炎症性眼病,炎症性或不稳定性膀胱病,银屑病,皮肤炎症成分炎症,慢性炎性病症,炎性疼痛及相关的痛觉过敏和异常性疼痛,神经性疼痛及相关的痛觉过敏和异常性疼痛,糖尿病性神经病疼痛, 咳嗽痛,交感神经痛,交感综合征,哮喘,上皮组织损伤或功能障碍,单纯疱疹,呼吸道内脏运动紊乱,泌尿生殖道,胃肠道或血管区,伤口,烧伤,过敏性皮肤反应,瘙痒症,白癜风,一般胃肠道疾病, G 腹部溃疡,十二指肠溃疡,腹泻,坏死因子诱发的胃损伤,毛发生长,血管舒缩或过敏性鼻炎,支气管疾病或膀胱疾病。
    • 8. 发明申请
    • Vanilloid receptor ligands and their use in treatments
    • 香草素受体配体及其在治疗中的应用
    • US20060089360A1
    • 2006-04-27
    • US11256427
    • 2005-10-21
    • Mark NormanVassil OgnyanovRobert Rzasa
    • Mark NormanVassil OgnyanovRobert Rzasa
    • A61K31/506C07D403/02C07D405/02
    • C07D401/04C07D403/04C07D405/04
    • Substituted nitrogen-containing heterocycles and compositions containing them, for the treatment of acute, inflammatory and neuropathic pain, dental pain, general headache, migraine, cluster headache, mixed-vascular and non-vascular syndromes, tension headache, general inflammation, arthritis, rheumatic diseases, osteoarthritis, inflammatory bowel disorders, inflammatory eye disorders, inflammatory or unstable bladder disorders, psoriasis, skin complaints with inflammatory components, chronic inflammatory conditions, inflammatory pain and associated hyperalgesia and allodynia, neuropathic pain and associated hyperalgesia and allodynia, diabetic neuropathy pain, causalgia, sympathetically maintained pain, deafferentation syndromes, asthma, epithelial tissue damage or dysfunction, herpes simplex, disturbances of visceral motility at respiratory, genitourinary, gastrointestinal or vascular regions, wounds, burns, allergic skin reactions, pruritus, vitiligo, general gastrointestinal disorders, gastric ulceration, duodenal ulcers, diarrhea, gastric lesions induced by necrotising agents, hair growth, vasomotor or allergic rhinitis, bronchial disorders or bladder disorders.
    • 取代的含氮杂环和含有它们的组合物,用于治疗急性,炎性和神经性疼痛,牙痛,一般头痛,偏头痛,丛集性头痛,混合血管和非血管性综合征,紧张性头痛,一般炎症,关节炎,风湿 疾病,骨关节炎,炎症性肠病,炎症性眼病,炎症性或不稳定性膀胱病,银屑病,皮肤炎症成分炎症,慢性炎性病症,炎性疼痛及相关的痛觉过敏和异常性疼痛,神经性疼痛及相关的痛觉过敏和异常性疼痛,糖尿病性神经病疼痛, 咳嗽痛,交感神经痛,交感综合征,哮喘,上皮组织损伤或功能障碍,单纯疱疹,呼吸道内脏运动紊乱,泌尿生殖道,胃肠道或血管区,伤口,烧伤,过敏性皮肤反应,瘙痒,白癜风,一般胃肠道紊乱 胃溃疡,十二指肠溃疡,腹泻,坏死因子诱导的胃损伤,毛发生长,血管舒缩或过敏性鼻炎,支气管疾病或膀胱疾病。
    • 10. 发明申请
    • Injection Nozzle
    • 注射喷嘴
    • US20070272772A1
    • 2007-11-29
    • US10575052
    • 2004-10-06
    • Malcolm LambertAndrew LimmerMark NormanMichael Mcloone
    • Malcolm LambertAndrew LimmerMark NormanMichael Mcloone
    • F02M61/00
    • F02M61/1873
    • An injection nozzle for an internal combustion engine has a valve member (10) with a seating line (112) defining a seat diameter, the seating line (112) being engageable with a seating surface (14) to control fuel injection by the nozzle, in use. The seating line is defined by an annular ridge (40, 44, 46), integrally formed with the valve needle (10), so as to reduce variations in the seat diameter which would otherwise arise at manufacture due to contact between the valve needle (10) and the seating surface (14) in regions other than at the seating line. The invention provides an advantage in manufacture as repeatability and consistency of the geometry, and in particular the effective seat diameter, of nozzle products is improved.
    • 用于内燃机的喷嘴具有阀构件(10),其具有限定座直径的座线(112),所述座线(112)可与座表面(14)接合以控制喷嘴的燃料喷射, 正在使用。 座位线由与阀针(10)一体形成的环形脊(40,44,46)限定,以便减小由于阀针(10)之间的接触而在制造时否将出现的座直径的变化 10)和座位表面(14)在除座位线以外的区域中。 本发明提供了制造中的优点,因为改进了喷嘴产品的几何形状的重复性和一致性,特别是有效的座椅直径。