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1. 再颁专利

USRE42836E1 Method for assessing cardiac functional status 有权
标题翻译：评估心脏功能状态的方法
公开(公告)号：USRE42836E1
公开(公告)日：2011-10-11
申请号：US11906742
申请日：2007-10-03
申请人： Weimin Sun , Veerichetty Kadhiresan , Bruce H. KenKnight , Richard S. Sanders
发明人： Weimin Sun , Veerichetty Kadhiresan , Bruce H. KenKnight , Richard S. Sanders
IPC分类号： A61N1/00
CPC分类号： A61N1/36542
摘要： A method for assessing cardiac function suitable for incorporation into an implantable cardiac rhythm management device. By measuring daily exertion levels in accordance with the invention, an assessment of cardiac function can be made that has been found to correlate well with conventional clinical classifications. The invention also provides for assessing cardiac function in conjunction with different pacing schemes designed to treat heart failure and using the assessment to select the best such scheme for the patient.
摘要翻译：一种用于评估心脏功能的方法，其适于并入植入式心律管理装置。通过测量根据本发明的每日运动水平，可以进行已经发现与常规临床分类良好相关的心脏功能的评估。本发明还提供了结合用于治疗心力衰竭的不同起搏方案和使用该评估为患者选择最佳的方案来评估心脏功能。

2. 发明授权

US06952611B2 Method for assessing cardiac functional status 有权
标题翻译：评估心脏功能状态的方法
公开(公告)号：US06952611B2
公开(公告)日：2005-10-04
申请号：US10136910
申请日：2002-04-30
申请人： Weimin Sun , Veerichetty Kadhiresan , Bruce H. KenKnight , Richard S. Sanders
发明人： Weimin Sun , Veerichetty Kadhiresan , Bruce H. KenKnight , Richard S. Sanders
IPC分类号： A61N1/365
CPC分类号： A61N1/36542
摘要： A method for assessing cardiac function suitable for incorporation into an implantable cardiac rhythm management device. By measuring daily exertion levels in accordance with the invention, an assessment of cardiac function can be made that has been found to correlate well with conventional clinical classifications. The invention also provides for assessing cardiac function in conjunction with different pacing schemes designed to treat heart failure and using the assessment to select the best such scheme for the patient.
摘要翻译：一种用于评估心脏功能的方法，其适于并入植入式心律管理装置。通过测量根据本发明的每日运动水平，可以进行已经发现与常规临床分类良好相关的心脏功能的评估。本发明还提供了结合用于治疗心力衰竭的不同起搏方案和使用该评估为患者选择最佳的方案来评估心脏功能。

3. 发明授权

US06473646B2 Method and apparatus for assessing cardiac functional status 有权
标题翻译：评估心脏功能状态的方法和装置
公开(公告)号：US06473646B2
公开(公告)日：2002-10-29
申请号：US09551310
申请日：2000-04-18
申请人： Weimin Sun , Veerichetty Kadhiresan , Bruce H. KenKnight , Richard S. Sanders
发明人： Weimin Sun , Veerichetty Kadhiresan , Bruce H. KenKnight , Richard S. Sanders
IPC分类号： A61N1362
CPC分类号： A61N1/36542
摘要： A method for assessing cardiac function suitable for incorporation into an implantable cardiac rhythm management device. By measuring daily exertion levels in accordance with the invention, an assessment of cardiac function can be made that has been found to correlate well with conventional clinical classifications. The invention also provides for assessing cardiac function in conjunction with different pacing schemes designed to treat heart failure and using the assessment to select the best such scheme for the patient.
摘要翻译：一种用于评估心脏功能的方法，其适于并入植入式心律管理装置。通过测量根据本发明的每日运动水平，可以进行已经发现与常规临床分类良好相关的心脏功能的评估。本发明还提供了结合用于治疗心力衰竭的不同起搏方案和使用该评估为患者选择最佳的方案来评估心脏功能。

4. 发明授权

US07353060B2 Adaptive anti-tachycardia therapy apparatus and method 有权
标题翻译：适应性抗心动过速治疗仪及方法
公开(公告)号：US07353060B2
公开(公告)日：2008-04-01
申请号：US10953081
申请日：2004-09-29
申请人： Weimin Sun , Bruce H. KenKnight , Martin Tze , Yatheendhar Manicka
发明人： Weimin Sun , Bruce H. KenKnight , Martin Tze , Yatheendhar Manicka
IPC分类号： A61N1/362
CPC分类号： A61N1/3962
摘要： A method and apparatus for delivering anti-tachycardia pacing in an adaptive manner is disclosed. A cardiac rhythm management device, such as an implantable pacemaker, having anti-tachycardia pacing capability delivers anti-tachycardia pacing therapy in accordance with a selected pacing protocol upon detection of a terminable arrhythmia. The protocol is selected from a library of available protocols. A record of the successes and failures of each available protocol in converting tachyarrhythmias is maintained in a result table for use in selecting the protocol.
摘要翻译：公开了以自适应方式递送抗心动过速起搏的方法和装置。具有抗心动过速起搏能力的心脏节律管理装置，例如可植入心脏起搏器，在检测到可终止的心律失常时，根据选定的起搏方案提供抗心动过速起搏治疗。协议从可用协议库中选择。在用于选择协议的结果表中保留了每种可用协议在转换快速性心律失常方面的成功和失败的记录。

5. 发明授权

US06230055B1 Method and apparatus for adaptive tachycardia and fibrillation discrimination 有权
标题翻译：适应性心动过速和原纤维化鉴别的方法和装置
公开(公告)号：US06230055B1
公开(公告)日：2001-05-08
申请号：US09378591
申请日：1999-08-20
申请人： Weimin Sun , Martin Tze , Bruce H. KenKnight , Yatheendhar Manicka
发明人： Weimin Sun , Martin Tze , Bruce H. KenKnight , Yatheendhar Manicka
IPC分类号： A61N137
CPC分类号： A61N1/3622 , A61N1/3962
摘要： An implantable cardioverter/defibrillator with antitachycardia pacing capability and method for operating same in which the detection zone boundary used to discriminate between tachycardia and fibrillation is adaptively adjusted based upon operating experience. Rate zones are provided for further classifying detected episodes of tachycardia and fibrillation according to the certainty of their being correctly identified based upon past operating experience. Adjustments of the rate zones and the fibrillation detection zone boundary are made based upon the results of antitachycardia pacing in attempting to terminate arrhythmic episodes.
摘要翻译：一种具有抗心动过速起搏能力的植入式心律转复除颤器及其操作方法，其中基于操作经验自适应调整用于区分心动过速和颤动的检测区边界。提供速率区，用于根据过去的操作经验正确识别检测到的心动过速和颤动发作进一步分类。基于抗心律失常起搏试图终止心律失常发作的结果，进行速率区和原纤维化检测区边界的调整。

6. 发明授权

US07729762B2 Adaptive anti-tachycardia therapy apparatus and method 有权
标题翻译：适应性抗心动过速治疗仪及方法
公开(公告)号：US07729762B2
公开(公告)日：2010-06-01
申请号：US11267071
申请日：2005-11-03
申请人： Weimin Sun , Bruce H. KenKnight , Martin Tze , Yatheendhar Manicka
发明人： Weimin Sun , Bruce H. KenKnight , Martin Tze , Yatheendhar Manicka
IPC分类号： A61N1/00
CPC分类号： A61N1/3962
摘要： A method and apparatus for delivering anti-tachycardia pacing in an adaptive manner is disclosed. A cardiac rhythm management device, such as an implantable pacemaker, having anti-tachycardia pacing capability delivers anti-tachycardia pacing therapy in accordance with a selected pacing protocol upon detection of a terminable arrhythmia. The protocol is selected from a library of available protocols. A record of the successes and failures of each available protocol in converting tachyarrhythmias is maintained in a result table for use in selecting the protocol.
摘要翻译：公开了以自适应方式递送抗心动过速起搏的方法和装置。具有抗心动过速起搏能力的心脏节律管理装置，例如可植入心脏起搏器，在检测到可终止的心律失常时，根据选定的起搏方案提供抗心动过速起搏治疗。协议从可用协议库中选择。在用于选择协议的结果表中保留了每种可用协议在转换快速性心律失常方面的成功和失败的记录。

7. 发明授权

US06801806B2 Adaptive anti-tachycardia therapy apparatus and method 失效
标题翻译：适应性抗心动过速治疗仪及方法
公开(公告)号：US06801806B2
公开(公告)日：2004-10-05
申请号：US10037622
申请日：2002-01-02
申请人： Weimin Sun , Bruce H. KenKnight , Martin Tze , Yatheendhar Manicka
发明人： Weimin Sun , Bruce H. KenKnight , Martin Tze , Yatheendhar Manicka
IPC分类号： A61N1362
CPC分类号： A61N1/3962
摘要： A method and apparatus for delivering anti-tachycardia pacing in an adaptive manner is disclosed. A cardiac rhythm management device, such as an implantable pacemaker, having anti-tachycardia pacing capability delivers anti-tachycardia pacing therapy in accordance with a selected pacing protocol upon detection of a terminable arrhythmia. The protocol is selected from a library of available protocols. A record of the successes and failures of each available protocol in converting tachyarrhythmias is maintained in a result table for use in selecting the protocol.
摘要翻译：公开了以自适应方式递送抗心动过速起搏的方法和装置。具有抗心动过速起搏能力的心脏节律管理装置，例如可植入心脏起搏器，在检测到可终止的心律失常时，根据选定的起搏方案提供抗心动过速起搏治疗。协议从可用协议库中选择。在用于选择协议的结果表中保留了每种可用协议在转换快速性心律失常方面的成功和失败的记录。

8. 发明授权

US06490485B1 Automatic rate-adaptive pacing with auto-lifestyle 有权
标题翻译：自动速率自适应起搏与自动生活方式
公开(公告)号：US06490485B1
公开(公告)日：2002-12-03
申请号：US09413663
申请日：1999-10-06
申请人： Weimin Sun , Bruce H. KenKnight , Douglas J. Lang
发明人： Weimin Sun , Bruce H. KenKnight , Douglas J. Lang
IPC分类号： A61N1365
CPC分类号： A61N1/365
摘要： Methods of adjusting output mapping in response to historical signal input data relative to a reference value, and apparatus to perform the methods. The methods are suited for use in adjusting rate-adaptive pacemakers in response to a patient's demonstrated activity relative to a predetermined activity level. The methods include using historical physiologic sensor input to derive a patient's activity. The methods further include tuning a rate-adaptive curve in response to a demonstrated exertion level and a demonstrated exertion time indicative of a breadth and frequency of a patient's activity above some reference value. Pacemakers adapted to perform the methods include a processor, at least one physiologic sensor, a variable-rate pulse generator and a memory for storing historical physiologic sensor data.
摘要翻译：响应于历史信号输入数据相对于参考值调整输出映射的方法以及执行方法的装置。该方法适用于响应于相对于预定活动水平的患者证明的活动来调整速率自适应起搏器。这些方法包括使用历史生理传感器输入来导出患者的活动。所述方法还包括响应于所证明的运动水平调整速率自适应曲线，以及指示患者活动的宽度和频率高于某个参考值的演示时间。适于执行该方法的起搏器包括处理器，至少一个生理传感器，可变速率脉冲发生器和用于存储历史生理传感器数据的存储器。

9. 发明授权

US06400986B1 Adaptive anti-tachycardia therapy apparatus and method 有权
标题翻译：适应性抗心动过速治疗仪及方法
公开(公告)号：US06400986B1
公开(公告)日：2002-06-04
申请号：US09545945
申请日：2000-04-10
申请人： Weimin Sun , Bruce H. KenKnight , Martin Tze , Yatheendhar Manicka
发明人： Weimin Sun , Bruce H. KenKnight , Martin Tze , Yatheendhar Manicka
IPC分类号： A61N1362
CPC分类号： A61N1/3962
摘要： A method and apparatus for delivering anti-tachycardia pacing in an adaptive manner is disclosed. A cardiac rhythm management device, such as an implantable pacemaker, having anti-tachycardia pacing capability delivers anti-tachycardia pacing therapy in accordance with a selected pacing protocol upon detection of a terminable arrhythmia. The protocol is selected from a library of available protocols. A record of the successes and failures of each available protocol in converting tachyarrhythmias is maintained in a result table for use in selecting the protocol.
摘要翻译：公开了以自适应方式递送抗心动过速起搏的方法和装置。具有抗心动过速起搏能力的心脏节律管理装置，例如可植入心脏起搏器，在检测到可终止的心律失常时，根据选定的起搏方案提供抗心动过速起搏治疗。协议从可用协议库中选择。在用于选择协议的结果表中保留了每种可用协议在转换快速性心律失常方面的成功和失败的记录。

10. 发明授权

US08755475B1 Maintaining linear beamforming weights in communications systems 有权
标题翻译：在通信系统中维持线性波束成形权重
公开(公告)号：US08755475B1
公开(公告)日：2014-06-17
申请号：US13411507
申请日：2012-03-02
申请人： Matthew C. Bromberg , Dale A. Branlund , Weimin Sun
发明人： Matthew C. Bromberg , Dale A. Branlund , Weimin Sun
IPC分类号： H03D1/04 , H03D1/06 , H03K5/01 , H03K6/04 , H04B1/10 , H04L1/00 , H04L25/08
CPC分类号： H04B7/0851 , H04B7/0617 , H04B17/345 , H04L1/0071 , H04L25/0234 , H04L25/03 , H04L25/03949
摘要： Methods and systems that enhance interference cancellation in communication channels are described. Samples are obtained from stacked carriers in a received signal and a data vector is created from the samples. Stacked carriers are selected using a steering vector received during synchronization of the receiver. The steering vector is calculated to obtain cancellation of interference from another receiver and is calculated based on time domain channel estimation. Specialized time domain training sequences and simple cross correlation are used to obtain a channel estimate for use in stacked carrier beamforming and/or for use in OFDM based spatial beamforming. State space or filter-based modeled interpolators or whitening matrix-filters in the frequency or time domain are used for interpolation of the channels to maintain linear beamforming weights as a function of time or frequency. Space time adaptive processing facilitates beamforming of communications signals for OFDM and 802.16 (WiMax) systems.
摘要翻译：描述了在通信信道中增强干扰消除的方法和系统。在接收信号中从堆叠载波获取样本，并从样本创建数据向量。使用在接收机同步期间接收到的导向矢量来选择堆叠的载波。计算导向矢量以获得来自另一接收机的干扰的抵消，并且基于时域信道估计来计算。使用专用时域训练序列和简单的互相关来获得用于堆叠载波波束成形和/或用于基于OFDM的空间波束形成中的信道估计。在频率或时域中的状态空间或基于滤波器的建模的内插器或白化矩阵滤波器被用于信道的插值，以维持作为时间或频率的函数的线性波束成形权重。空时自适应处理有利于OFDM和802.16（WiMax）系统的通信信号的波束成形。

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