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1. 发明授权

US06464650B2 Guidewire with smoothly tapered segment 有权
标题翻译：导丝平滑锥形
公开(公告)号：US06464650B2
公开(公告)日：2002-10-15
申请号：US09224451
申请日：1998-12-31
申请人： Mo Jafari , Sepehr Fariabi , Lawrence E. Brennan , Wayne E. Cornish , Marc M. Jalisi , David M. Anderson
发明人： Mo Jafari , Sepehr Fariabi , Lawrence E. Brennan , Wayne E. Cornish , Marc M. Jalisi , David M. Anderson
IPC分类号： A61B500
CPC分类号： A61M25/09 , A61M2025/09175
摘要： A guidewire for intraluminal advancement of a medical device within a patient which has an elongate core member with a flexible body member disposed on a distal section thereof. In one embodiment, the distal section of the elongate core member has at least one flexible segment with at least one pair of opposed tapered or parallel faces. Preferably the flexible segment with the tapered or parallel faces is disposed at the distal end of the elongate core and forms a shapable segment.
摘要翻译：一种用于管腔内推进医疗装置的导丝，其具有细长的芯部件，其具有设置在其远端部分上的柔性主体部件。在一个实施例中，细长芯部件的远端部分具有至少一个具有至少一对相对的锥形或平行面的柔性部分。优选地，具有锥形或平行面的柔性段设置在细长芯的远端并形成可成形段。

2. 发明申请

US20080146967A1 Polymer coated guidewire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US20080146967A1
公开(公告)日：2008-06-19
申请号：US10631275
申请日：2003-07-31
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61M25/00
CPC分类号： A61L31/10 , A61L31/18 , A61M25/0045 , A61M25/0054 , A61M25/09 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under fluoroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间断的，连续的或呈螺旋状的形式，用于在透视成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

3. 发明授权

US06673025B1 Polymer coated guidewire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US06673025B1
公开(公告)日：2004-01-06
申请号：US09441698
申请日：1999-11-16
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61B500
CPC分类号： A61M25/09 , A61M2025/09175
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under flouroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间歇的，连续的或以螺旋带的形式，用于在荧光成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

4. 发明授权

US07494474B2 Polymer coated guidewire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US07494474B2
公开(公告)日：2009-02-24
申请号：US10631275
申请日：2003-07-31
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61L31/10 , A61L31/18 , A61M25/0045 , A61M25/0054 , A61M25/09 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under fluoroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间断的，连续的或呈螺旋状的形式，用于在透视成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

5. 发明授权

US06491648B1 Guidewire with tapered flexible core segment 有权
标题翻译：导丝带锥形柔性芯段
公开(公告)号：US06491648B1
公开(公告)日：2002-12-10
申请号：US09748299
申请日：2000-12-21
申请人： Wayne E. Cornish , Mark T. Richardson , Lawrence E. Brennan , Marc M. Jalisi , David M. Anderson , Mo Jafari , Sepehr Fariabi
发明人： Wayne E. Cornish , Mark T. Richardson , Lawrence E. Brennan , Marc M. Jalisi , David M. Anderson , Mo Jafari , Sepehr Fariabi
IPC分类号： A61B500
CPC分类号： A61M25/09 , A61M2025/09175
摘要： A guidewire for guiding a medical device within a patient which has an elongate core member with a flexible body member disposed about and secured to a distal core section and a flexible core segment or flexible core segment which has a first pair of opposed faces which define a first transverse dimension that tapers from a first value to a second larger value and a second pair of opposed faces which define a second transverse dimension that tapers from a first value to a second smaller value.
摘要翻译：一种用于在具有细长芯部件的患者体内引导医疗装置的导丝，其具有设置在远端芯部周围并固定到远端芯部的柔性主体部件以及具有第一对相对面的柔性芯部或柔性芯部，从第一值逐渐变细到第二较大值的第一横向尺寸和限定从第一值到第二较小值逐渐变细的第二横向尺寸的第二对相对面。

6. 发明授权

US07455646B2 Polymer coated guide wire 有权
标题翻译：聚合物涂层导丝
公开(公告)号：US07455646B2
公开(公告)日：2008-11-25
申请号：US11768794
申请日：2007-06-26
申请人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
发明人： Mark T. Richardson , David M. Anderson , Emmanuel C. Biagtan , Lawrence E. Brennan , David H. Burkett , Wayne E. Cornish , Robert C. Esselstein , James Jacobs , Marc M. Jalisi , Daryush P. Mirzaee , Olin J. Palmer , John Schreiner , Kent C. Stalker
IPC分类号： A61B5/00 , A61M25/00
CPC分类号： A61M25/09 , A61L31/10 , A61L31/18 , A61M25/0045 , A61M25/0054 , A61M2025/09083 , A61M2025/09133 , A61M2025/09166
摘要： A guidewire or section thereof, that has a core member or the like with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal portion of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that is configured to produce a linear change in stiffness of the core over a longitudinal portion of the device. An embodiment has a plurality of radiopaque elements that may be intermittent, continuous or in the form of a helical ribbon for scaled measurement of intracorporeal structure under flouroscopic imaging. Another embodiment has at least one layer of polymer over the distal end of the device.
摘要翻译：具有芯构件等的导丝或其一部分具有多个具有锥形角度的相邻锥形段的构造，以在该装置的纵向部分上产生线性的刚度变化。该装置还可以具有连续变化的锥角的芯部，以产生曲线轮廓，其被配置成在装置的纵向部分上产生芯的刚度的线性变化。一个实施例具有多个不透射线的元件，其可以是间歇的，连续的或以螺旋带的形式，用于在荧光成像下对体内结构进行缩放测量。另一个实施方案在装置的远端上具有至少一层聚合物。

7. 发明授权

US06652472B2 Guidewire with smoothly tapered segment 有权
公开(公告)号：US06652472B2
公开(公告)日：2003-11-25
申请号：US10186858
申请日：2002-07-01
申请人： Mo Jafari , Sepehr Fariabi , Lawrence E. Brennan , Wayne E. Cornish , Marc M. Jalisi , David M. Anderson
发明人： Mo Jafari , Sepehr Fariabi , Lawrence E. Brennan , Wayne E. Cornish , Marc M. Jalisi , David M. Anderson
IPC分类号： A61B500
CPC分类号： A61M25/09 , A61M2025/09175
摘要： A guidewire for intraluminal advancement of a medical device within a patient which has an elongate core member with a flexible body member disposed on a distal section thereof. In one embodiment, the distal section of the elongate core member has at least one flexible segment with at least one pair of opposed tapered or parallel faces. Preferably the flexible segment with the tapered or parallel faces is disposed at the distal end of the elongate core and forms a shapable segment.

8. 发明授权

US6132389A Proximally tapered guidewire tip coil 失效
标题翻译：近端锥形导丝尖端线圈
公开(公告)号：US6132389A
公开(公告)日：2000-10-17
申请号：US65646
申请日：1998-04-23
申请人： Wayne E. Cornish , Lawrence E. Brennan , David M. Anderson , Marc M. Jalisi
发明人： Wayne E. Cornish , Lawrence E. Brennan , David M. Anderson , Marc M. Jalisi
IPC分类号： A61B20060101 , A61B5/00 , A61M25/01 , A61M25/09
CPC分类号： A61M25/09 , A61M2025/09083 , A61M2025/09175
摘要： The disclosure is directed to a guidewire having an elongate core member with at least one distally tapered portion at the distal section, with a flexible body member disposed around said distal section. The flexible body member is preferably comprised of a metallic helical coil that has proximally tapered portion at the proximal end, with a diameter similar to the outer diameter of the elongate core member at the point of attachment thereto. The distal end of the flexible body member is attached to the distal end of the elongate core member. The proximal taper of the flexible body member provides a smooth transition from the elongate core member to the flexible body member while minimizing the amount of bonding material needed and the resulting localized stiff portion at the point of connection between the proximal end of the flexible body member and the elongate body member.
摘要翻译：本发明涉及一种具有细长芯部件的导丝，该细长芯部件在远端部分具有至少一个远端锥形部分，其中柔性主体部件设置在所述远端部分周围。柔性本体构件优选地包括金属螺旋线圈，该螺旋线圈在近端具有近端锥形部分，其直径与附接到其上的细长芯构件的外径相似。柔性本体构件的远端附接到细长芯构件的远端。柔性主体构件的近端锥形提供从细长芯构件到柔性主体构件的平滑过渡，同时最小化所需的接合材料的量以及在柔性本体构件的近端之间的连接点处的所得到的局部刚性部分和细长主体构件。

9. 发明申请

US20100004562A1 COMPOSITE GUIDEWIRE WITHDRAWN AND FILLED TUBE CONSTRUCTION 有权
标题翻译：复合导向装置和填充管道结构
公开(公告)号：US20100004562A1
公开(公告)日：2010-01-07
申请号：US12554178
申请日：2009-09-04
申请人： Marc M. Jalisi , David M. Anderson , Wayne E. Cornish , Nancy A. Nicotra , Mark T. Richardson
发明人： Marc M. Jalisi , David M. Anderson , Wayne E. Cornish , Nancy A. Nicotra , Mark T. Richardson
IPC分类号： A61M25/09
CPC分类号： A61M25/09 , A61M2025/09175
摘要： The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation hardened material. The elongate core members of the present invention will have an ultimate tensile strength and modulus of elasticity greater than the same for an identically dimensioned elongate member formed from superelastic NITINOL alone.
摘要翻译：本发明涉及体内装置，优选导丝，以及制造该装置的方法。本发明的导丝至少部分地形成有至少部分由沉淀硬化材料形成的复合细长芯。对于由超弹性NITINOL单独形成的相同尺寸的细长构件，本发明的细长芯构件将具有大于相同尺寸的极限拉伸强度和弹性模量。

10. 发明授权

US08226577B2 Composite guidewire withdrawn and filled tube construction 有权
标题翻译：复合导丝取出并填充管结构
公开(公告)号：US08226577B2
公开(公告)日：2012-07-24
申请号：US12554178
申请日：2009-09-04
申请人： Marc M. Jalisi , David M. Anderson , Wayne E. Cornish , Nancy A. Nicotra , Mark T. Richardson
发明人： Marc M. Jalisi , David M. Anderson , Wayne E. Cornish , Nancy A. Nicotra , Mark T. Richardson
IPC分类号： A61B5/00
CPC分类号： A61M25/09 , A61M2025/09175
摘要： The present invention is directed to an intracorporeal device, preferably a guidewire, and method for making the device. The guidewire of the present invention is formed, at least in part, of a composite elongate core formed, at least in part, of precipitation hardened material. The elongate core members of the present invention will have an ultimate tensile strength and modulus of elasticity greater than the same for an identically dimensioned elongate member formed from superelastic NITINOL alone.
摘要翻译：本发明涉及体内装置，优选导丝，以及制造该装置的方法。本发明的导丝至少部分地形成有至少部分由沉淀硬化材料形成的复合细长芯。对于由超弹性NITINOL单独形成的相同尺寸的细长构件，本发明的细长芯构件将具有大于相同尺寸的极限拉伸强度和弹性模量。

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