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    • 8. 发明申请
    • PIEZOELECTRIC MICROCANTILEVERS AND USES IN ATOMIC FORCE MICROSCOPY
    • 压电微晶器在原子力显微镜中的应用
    • US20110265227A1
    • 2011-10-27
    • US13160304
    • 2011-06-14
    • WAN Y. SHIHWEI-HENG SHIHZUYAN SHENQING ZHU
    • WAN Y. SHIHWEI-HENG SHIHZUYAN SHENQING ZHU
    • G01Q60/24
    • G01Q60/38B82Y35/00G01B9/04G01Q10/045G01Q20/04Y10T29/42
    • The invention is direct to a piezoelectric microcantilever for static contact and dynamic noncontact atomic force microscopy which may be carried out in solution. The piezoelectric microcantilever, which includes a piezoelectric layer and a non-piezoelectric layer is capable of self actuation and detection. The piezoelectric layer may be constructed from a lead magnesium niobate-lead titanate (Pb(Mg1/3Nb2/3)O3)0.65—(PbTiO3)0.35(PMN0.65-PT0.35) (PMN-PT), zirconate titanate (PZT)/SiO2 or from any lead-free piezoelectric materials such as doped sodium-potassium niobate-lithium niobate. The piezoelectric layers of the microcantilevers may have dielectric constants of from 1600-3000 and thicknesses below 10 μm. Also disclosed are methods for fabricating microcantilever sensors and methods for atomic force microscopy employing the microcantilevers.
    • 本发明直接用于静态接触和动态非接触原子力显微镜的压电微悬臂梁,其可以在溶液中进行。 包括压电层和非压电层的压电微悬臂梁能够自动启动和检测。 压电层可以由铌酸铅镁酸铅(Pb(Mg1 / 3Nb2 / 3)O3)0.65-(PbTiO3)0.35(PMN0.65-PT0.35)(PMN-PT),锆钛酸铅(PZT) )/ SiO 2或来自任何无铅压电材料如掺杂的铌酸钠 - 铌酸锂 - 铌酸锂。 微悬臂梁的压电层可以具有1600-3000的介电常数和低于10μm的厚度。 还公开了用于制造微悬臂梁传感器的方法和使用微悬臂梁的原子力显微镜的方法。
    • 9. 发明申请
    • WATER SOLUBLE QUANTUM DOTS
    • 水可溶量子
    • US20100008861A1
    • 2010-01-14
    • US12552970
    • 2009-09-02
    • WEI-HENG SHIHWAN Y. SHIHHUI LIMELISSA COLLEEN SCHILLO
    • WEI-HENG SHIHWAN Y. SHIHHUI LIMELISSA COLLEEN SCHILLO
    • A61K51/04C07C53/122C07F3/08C07F7/24C07F13/00
    • C09K11/565B82Y5/00B82Y10/00B82Y30/00C09K11/883Y10S977/774
    • An economic, direct synthetic method for producing water soluble QDs that are ready for bioconjugation is provided. The method can produce aqueous QDs with emission wavelengths varying from 400 nm to 700 nm Highly luminescent metal sulfide (MS) QDs are produced via an aqueous synthesis route. MS QDs are capped with thiol-containing charged molecules in a single step. The resultant MS QDs exhibit the distinctive excitonic photoluminescence desired of QDs and can be fabricated to avoid undesirable broadband emissions at higher wavelengths. This provides a significant improvement over the present complex and expensive commercial processes for the production of QDs. The aqueous QDs are stable in biological fluids over a long period of time. In addition, nontoxic ZnS QDs have been produced with good photoluminescence properties by refluxing the ZnS QD suspensions over a period of time.
    • 提供了一种用于生产水溶性量子点的经济,直接的合成方法,可用于生物共轭。 该方法可以产生发射波长从400nm到700nm变化的含水量子点。高发光金属硫化物(MS)量子点通过水性合成途径产生。 在一个步骤中,MS量子点被含硫醇的带电分子封盖。 所得的MS量子点显示量子点所需的独特的激子光致发光,并且可以被制造以避免在较高波长处的不期望的宽带发射。 这提供了相对于目前用于生产量子点的复杂和昂贵的商业过程的显着改进。 水质量子在长时间内在生物体液中是稳定的。 此外,通过在一段时间内回流ZnS QD悬浮液,已经生产出具有良好光致发光性质的无毒ZnS量子点。