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1. 发明授权

US11679240B2 Removable covers for drug eluting medical devices 有权
公开(公告)号：US11679240B2
公开(公告)日：2023-06-20
申请号：US16783612
申请日：2020-02-06
申请人： W. L. Gore & Associates, Inc.
发明人： Edward H. Cully , Jeffrey B. Duncan , Peter Heicksen , Joseph B. Koenig , Jeffrey J. Kustusch
IPC分类号： A61M25/10 , A61F2/97 , A61L29/04 , A61L29/08 , A61M25/06 , A61F2/958 , A61F2/95
CPC分类号： A61M25/10184 , A61F2/95 , A61F2/958 , A61F2/97 , A61L29/041 , A61L29/085 , A61M25/0668 , A61F2002/9583 , A61M25/1011 , A61M2025/0681 , A61M2025/105 , A61M2025/1081 , A61L29/085 , C08L27/18 , A61L29/041 , C08L27/18
摘要： The present disclosure includes an expandable medical device and outer sheath combination. The outer sheath is capable of being split to form multiple sheath sections that may be peeled back to expose a portion or all of the expandable medical device. The medical device, as well as the outer sheath, may include one or more therapeutic agents for delivery to a treatment area within a patient.

2. 发明授权

US11116621B2 Elastic stent graft 有权
公开(公告)号：US11116621B2
公开(公告)日：2021-09-14
申请号：US15902567
申请日：2018-02-22
申请人： W. L. Gore & Associates, Inc.
发明人： Edward H. Cully , Jeffrey B. Duncan , Ryan D. Kariniemi , Thomas E. Kariniemi , Jeffrey J. Kustusch , Jared S. Nelson
IPC分类号： A61F2/07 , A61L31/04
摘要： A stent graft including a stent having a wall having at least one opening, an outer surface, and an inner surface and a covering of a composite material having a least one expanded fluoropolymer membrane and an elastomer is provided. The cover can be used to cover the outer and/or the inner surface of the stent. The expanded fluoropolymer membrane contains serpentine fibrils. In exemplary embodiments, the fluoropolymer is polytetrafluoroethylene. The composite material may be axially and/or circumferentially wrapped around the stent. The composite material is fold-free throughout its operating diameter range and exhibits a sharp increase in stiffness at a predetermined diameter. The stent graft can be designed to have a stop point in either a radial or axial direction. The stent graft can advantageously be implanted undersized with respect to a nominal diameter without having material infolding.

3. 发明申请

US20160096006A1 REMOVABLE COVERS FOR DRUG ELUTING MEDICAL DEVICES 审中-公开
标题翻译：用于药物治疗医疗器械的可拆卸盖子
公开(公告)号：US20160096006A1
公开(公告)日：2016-04-07
申请号：US14872439
申请日：2015-10-01
申请人： W. L. Gore & Associates, Inc.
发明人： Edward H. Cully , Jeffrey B. Duncan , Peter Heicksen , Joseph B. Koenig , Jeffrey J. Kustusch
IPC分类号： A61M25/10 , A61F2/95
摘要： The present disclosure includes an expandable medical device and outer sheath combination. The outer sheath is capable of being split to form multiple sheath sections that may be peeled back to expose a portion or all of the expandable medical device. The medical device, as well as the outer sheath, may include one or more therapeutic agents for delivery to a treatment area within a patient.
摘要翻译：本公开包括可扩张医疗装置和外护套组合。外护套能够被分开以形成多个护套部分，其可被剥离以暴露可扩张医疗装置的一部分或全部。医疗装置以及外护套可以包括用于递送到患者内的治疗区域的一种或多种治疗剂。

4. 发明申请

US20190216592A1 ELASTIC STENT GRAFT 审中-公开
公开(公告)号：US20190216592A1
公开(公告)日：2019-07-18
申请号：US16248490
申请日：2019-01-15
申请人： W. L. Gore & Associates, Inc.
发明人： Edward H. Cully , Jeffrey B. Duncan , Ryan D. Kariniemi , Thomas E. Kariniemi , Jeffrey J. Kustusch , Jared S. Nelson
IPC分类号： A61F2/07 , A61L31/04
CPC分类号： A61F2/07 , A61F2002/072 , A61L31/048 , C08L27/18
摘要： A stent graft including (1) a stent having a wall having at least one opening, an outer surface, and an inner surface and (2) a covering of a composite material having a least one expanded fluoropolymer membrane and an elastomer is provided. The cover can be used to cover the outer and/or the inner surface of the stent. The expanded fluoropolymer membrane contains serpentine fibrils. In exemplary embodiments, the fluoropolymer is polytetrafluoroethylene. The composite material may be axially and/or circumferentially wrapped around the stent. The composite material is fold-free throughout its operating diameter range and exhibits a sharp increase in stiffness at a predetermined diameter. The stent graft can be designed to have a stop point in either a radial or axial direction. The stent graft can advantageously be implanted undersized with respect to a nominal diameter without having material infolding.

5. 发明申请

US20180125683A1 STENT HAVING ADJACENT ELEMENTS CONNECTED BY NARROW FLEXIBLE WEBS 审中-公开
公开(公告)号：US20180125683A1
公开(公告)日：2018-05-10
申请号：US15865579
申请日：2018-01-09
申请人： W. L. Gore & Associates, Inc.
发明人： Ryan D. Kariniemi , Jeffrey J. Kustusch , Mark J. Ulm
IPC分类号： A61F2/89
CPC分类号： A61F2/89 , A61F2/07 , A61F2/86 , A61F2/915 , A61F2002/828 , A61F2002/91558 , A61F2210/0066 , A61F2210/0076 , A61F2220/005 , A61F2230/0069 , A61F2240/001 , A61F2250/0018 , A61F2250/002 , A61F2250/0029 , A61F2250/0068
摘要： A stent and method of making incorporating flexible, preferably polymeric, connecting elements into the stent wherein these elements connect element(s) across an intervening space. The polymeric connecting elements are designed to fold within the space between the outer diameter of the stent and the inner diameter of the stent.

6. 发明申请

US20160015538A1 STENT HAVING ADJACENT ELEMENTS CONNECTED BY NARROW FLEXIBLE WEBS 有权
标题翻译：具有由NARROW柔性WEBS连接的相似元素的STENT
公开(公告)号：US20160015538A1
公开(公告)日：2016-01-21
申请号：US14801486
申请日：2015-07-16
申请人： W. L. Gore & Associates, Inc.
发明人： Ryan D. Kariniemi , Jeffrey J. Kustusch , Mark J. Ulm
IPC分类号： A61F2/89
CPC分类号： A61F2/89 , A61F2/07 , A61F2/86 , A61F2/915 , A61F2002/828 , A61F2002/91558 , A61F2210/0066 , A61F2210/0076 , A61F2220/005 , A61F2230/0069 , A61F2240/001 , A61F2250/0018 , A61F2250/002 , A61F2250/0029 , A61F2250/0068
摘要： A stent incorporating flexible, preferably polymeric, connecting elements into the stent wherein these elements connect adjacent metallic stent element(s) across an intervening space and have optimized geometries. In one configuration the metallic elements are the result of forming the stent from a helically wound serpentine wire having intervening spaces between adjacent helical windings of the wire. The polymeric connecting elements are designed to fold within the space between the outer diameter of the stent and the inner diameter of the stent when the stent is subjected to compaction or bending. Other stent forms such as multiple, individual spaced-apart ring-shaped or interconnected stent elements may also be used.
摘要翻译：支架将柔性，优选聚合的连接元件结合到支架中，其中这些元件将相邻的金属支架元件连接在中间空间上并且具有优化的几何形状。在一种配置中，金属元件是由螺旋缠绕的蛇形线形成支架的结果，其在线的相邻螺旋形绕组之间具有间隔空间。聚合物连接元件被设计成当支架经受压实或弯曲时在支架的外径和支架的内径之间的空间内折叠。还可以使用其它支架形式，例如多个，单独间隔开的环形或互连的支架元件。

7. 发明申请

US20220331089A1 ELASTIC STENT GRAFT 有权
公开(公告)号：US20220331089A1
公开(公告)日：2022-10-20
申请号：US17741774
申请日：2022-05-11
申请人： W. L. Gore & Associates, Inc.
发明人： Edward H. Cully , Jeffrey B. Duncan , Ryan D. Kariniemi , Thomas E. Kariniemi , Jeffrey J. Kustusch , Jared S. Nelson
IPC分类号： A61F2/07 , A61L31/04
摘要： A stent graft including (1) a stent having a wall having at least one opening, an outer surface, and an inner surface and (2) a covering of a composite material having a least one expanded fluoropolymer membrane and an elastomer is provided. The cover can be used to cover the outer and/or the inner surface of the stent. The expanded fluoropolymer membrane contains serpentine fibrils. In exemplary embodiments, the fluoropolymer is polytetrafluoroethylene. The composite material may be axially and/or circumferentially wrapped around the stent. The composite material is fold-free throughout its operating diameter range and exhibits a sharp increase in stiffness at a predetermined diameter. The stent graft can be designed to have a stop point in either a radial or axial direction. The stent graft can advantageously be implanted undersized with respect to a nominal diameter without having material infolding.

8. 发明授权

US11357611B2 Elastic stent graft 有权
公开(公告)号：US11357611B2
公开(公告)日：2022-06-14
申请号：US16248490
申请日：2019-01-15
申请人： W. L. Gore & Associates, Inc.
发明人： Edward H. Cully , Jeffrey B. Duncan , Ryan D. Kariniemi , Thomas E. Kariniemi , Jeffrey J. Kustusch , Jared S. Nelson
IPC分类号： A61M21/02 , A61B5/00 , A61B5/11 , A61F2/07 , A61L31/04
摘要： A stent graft including a stent having a wall having at least one opening, an outer surface, and an inner surface and a covering of a composite material having a least one expanded fluoropolymer membrane and an elastomer is provided. The cover can be used to cover the outer and/or the inner surface of the stent. The expanded fluoropolymer membrane contains serpentine fibrils. In exemplary embodiments, the fluoropolymer is polytetrafluoroethylene. The composite material may be axially and/or circumferentially wrapped around the stent. The composite material is fold-free throughout its operating diameter range and exhibits a sharp increase in stiffness at a predetermined diameter. The stent graft can be designed to have a stop point in either a radial or axial direction. The stent graft can advantageously be implanted undersized with respect to a nominal diameter without having material infolding.

9. 发明授权

US09895243B2 Stent having adjacent elements connected by narrow flexible webs 有权
公开(公告)号：US09895243B2
公开(公告)日：2018-02-20
申请号：US14801486
申请日：2015-07-16
申请人： W. L. Gore & Associates, Inc.
发明人： Ryan D. Kariniemi , Jeffrey J. Kustusch , Mark J. Ulm
IPC分类号： A61F2/07 , A61F2/89 , A61F2/86 , A61F2/915 , A61F2/82
CPC分类号： A61F2/89 , A61F2/07 , A61F2/86 , A61F2/915 , A61F2002/828 , A61F2002/91558 , A61F2210/0066 , A61F2210/0076 , A61F2220/005 , A61F2230/0069 , A61F2240/001 , A61F2250/0018 , A61F2250/002 , A61F2250/0029 , A61F2250/0068
摘要： A stent incorporating flexible, preferably polymeric, connecting elements into the stent wherein these elements connect adjacent metallic stent element(s) across an intervening space and have optimized geometries. In one configuration the metallic elements are the result of forming the stent from a helically wound serpentine wire having intervening spaces between adjacent helical windings of the wire. The polymeric connecting elements are designed to fold within the space between the outer diameter of the stent and the inner diameter of the stent when the stent is subjected to compaction or bending. Other stent forms such as multiple, individual spaced-apart ring-shaped or interconnected stent elements may also be used.

10. 发明申请

US20140135897A1 Elastic Stent Graft 有权
标题翻译：弹性支架移植
公开(公告)号：US20140135897A1
公开(公告)日：2014-05-15
申请号：US13755481
申请日：2013-01-31
申请人： W. L. GORE & ASSOCIATES, INC.
发明人： Edward H. Cully , Jeffrey B. Duncan , Ryan D. Kariniemi , Thomas E. Kariniemi , Jeffrey J. Kustusch , Jared S. Nelson
IPC分类号： A61F2/07
CPC分类号： A61F2/07 , A61F2002/072 , A61L31/048 , C08L27/18
摘要： A stent graft including (1) a stent having a wall having at least one opening, an outer surface, and an inner surface and (2) a covering of a composite material having a least one expanded fluoropolymer membrane and an elastomer is provided. The cover can be used to cover the outer and/or the inner surface of the stent. The expanded fluoropolymer membrane contains serpentine fibrils. In exemplary embodiments, the fluoropolymer is polytetrafluoroethylene. The composite material may be axially and/or circumferentially wrapped around the stent. The composite material is fold-free throughout its operating diameter range and exhibits a sharp increase in stiffness at a predetermined diameter. The stent graft can be designed to have a stop point in either a radial or axial direction. The stent graft can advantageously be implanted undersized with respect to a nominal diameter without having material infolding.
摘要翻译：一种覆膜支架，其包括（1）具有至少一个开口的壁的支架，外表面和内表面，以及（2）具有至少一个膨胀的含氟聚合物膜和弹性体的复合材料的覆盖物。盖可用于覆盖支架的外表面和/或内表面。膨胀的含氟聚合物膜含有蛇纹石原纤维。在示例性实施方案中，含氟聚合物是聚四氟乙烯。复合材料可以围绕支架轴向和/或周向缠绕。复合材料在其整个工作直径范围内是无折叠的，并且在预定直径处表现出刚度的急剧增加。支架移植物可以设计成在径向或轴向方向上具有停止点。支架移植物可以有利地相对于标称直径而不是材料折叠地被植入到尺寸不足的地方。

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