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1. 发明申请

US20100178342A1 Solid Pharmaceutical Preparation 审中-公开
标题翻译：固体药物制剂
公开(公告)号：US20100178342A1
公开(公告)日：2010-07-15
申请号：US12730831
申请日：2010-03-24
申请人： Ulrich Brauns , Thomas Friedl , Sabine Landerer
发明人： Ulrich Brauns , Thomas Friedl , Sabine Landerer
IPC分类号： A61K9/28 , A61K31/46 , A61P25/16 , A61P25/28 , B05D1/02
CPC分类号： A61K9/1652 , A61K9/1623 , A61K9/2018 , A61K9/2054 , A61K9/2813 , A61K9/2866 , A61K31/46
摘要： The invention relates to a solid pharmaceutical preparation containing one or more solid carriers and/or excipients and an active substance selected from among the Monoamine Neurotransmitter Re-uptake Inhibitors which have a 2,3-disubstituted tropane structure, the preparation thereof and use thereof for preparing a pharmaceutical composition for the treatment or prevention of central-nervous diseases or disorders.
摘要翻译：本发明涉及含有一种或多种固体载体和/或赋形剂的固体药物制剂和选自具有2,3-二取代托烷结构的单胺神经递质再摄取抑制剂的活性物质，其制备及其用途制备用于治疗或预防中枢神经疾病或病症的药物组合物。

2. 发明申请

US20050124651A1 Solid pharmaceutical preparation 审中-公开
标题翻译：固体药物制剂
公开(公告)号：US20050124651A1
公开(公告)日：2005-06-09
申请号：US10987831
申请日：2004-11-12
申请人： Ulrich Brauns , Thomas Friedl , Sabine Landerer
发明人： Ulrich Brauns , Thomas Friedl , Sabine Landerer
IPC分类号： A61K9/16 , A61K9/20 , A61K9/28 , A61K31/46
CPC分类号： A61K9/1652 , A61K9/1623 , A61K9/2018 , A61K9/2054 , A61K9/2813 , A61K9/2866 , A61K31/46
摘要： The invention relates to a solid pharmaceutical preparation containing one or more solid carriers and/or excipients and an active substance selected from among the Monoamine Neurotransmitter Re-uptake Inhibitors which have a 2,3-disubstituted tropane structure, the preparation thereof and use thereof for preparing a pharmaceutical composition for the treatment or prevention of central-nervous diseases or disorders.
摘要翻译：本发明涉及含有一种或多种固体载体和/或赋形剂的固体药物制剂和选自具有2,3-二取代托烷结构的单胺神经递质再摄取抑制剂的活性物质，其制备及其用途制备用于治疗或预防中枢神经疾病或病症的药物组合物。

3. 发明申请

US20110129538A1 PROCESS FOR PREPARING ORALLY ADMINISTERED DABIGATRAN FORMULATIONS 审中-公开
标题翻译：准备管理的DABIGATRAN制剂的方法
公开(公告)号：US20110129538A1
公开(公告)日：2011-06-02
申请号：US12934727
申请日：2009-03-24
申请人： Sabine Landerer , Thomas Friedl
发明人： Sabine Landerer , Thomas Friedl
IPC分类号： A61K9/14 , A61K31/4439
CPC分类号： A61K9/5089 , A61K9/1617 , A61K9/1652 , A61K9/4816 , A61K9/485 , A61K9/4866 , A61K31/4439
摘要： The invention relates to an improved process for preparing a new medicament formulation of the active substance dabigatran etexilate of formula I in the form of the methanesulphonic acid salt thereof, and this new medicament formulation as such.
摘要翻译：本发明涉及一种用于制备其甲磺酸盐形式的式I的活性物质达比加群酯的新药物制剂的改进方法，以及这种新的药物制剂。

4. 发明授权

US08590278B2 Method for the fluid-tight sealing of filled medicament capsules 有权
标题翻译：填充药物胶囊的流体密封方法
公开(公告)号：US08590278B2
公开(公告)日：2013-11-26
申请号：US13530618
申请日：2012-06-22
申请人： Josef Boldis , Sabine Landerer , Thorsten Neuhaus
发明人： Josef Boldis , Sabine Landerer , Thorsten Neuhaus
IPC分类号： A61J3/07 , B65B31/04
CPC分类号： A61J3/071 , A61J3/072 , A61J3/074
摘要： The present invention relates to a method, a device, and a control program for the fluid-tight sealing of capsules containing medicaments, wherein the capsules consist of at least one capsule body and a capsule cap which are set one into the other telescopically and provided with a tight band in the abutment region on the exterior side of the capsule, wherein the capsule components are filled with gas which has a changed temperature and/or a changed pressure in relation to the environment, and wherein a reduction of the difference in pressure in the capsule occurs via gaps between capsule body and capsule cap after the capsule components have been placed one inside the other. The capsules produced via the method according to the invention are disposable capsules and preferably contain a single dose of an orally administered pharmaceutical formulation in the form of a powder or a liquid.
摘要翻译：本发明涉及一种用于流体密封包含药物的胶囊的方法，装置和控制程序，其中胶囊由至少一个胶囊主体和胶囊盖组成，该胶囊主体和胶囊盖可伸缩地设置在另一个中，在胶囊的外侧上的邻接区域中具有紧密带，其中胶囊部件填充有相对于环境具有改变的温度和/或变化的压力的气体，并且其中压力差的减小在胶囊部件已经被放置在另一个内部之后，胶囊通过胶囊主体和胶囊盖之间的间隙发生。通过根据本发明的方法制备的胶囊是一次性胶囊，并且优选含有单剂量的粉末形式或液体形式的口服药物制剂。

5. 发明申请

US20100212261A1 Tight sealing of filled medicament capsules 审中-公开
标题翻译：填充药物胶囊密封
公开(公告)号：US20100212261A1
公开(公告)日：2010-08-26
申请号：US12667887
申请日：2008-07-08
申请人： Josef Boldis , Sabine Landerer , Thorsten Neuhaus
发明人： Josef Boldis , Sabine Landerer , Thorsten Neuhaus
IPC分类号： A61J3/07 , B65B31/00
CPC分类号： A61J3/071 , A61J3/072 , A61J3/074
摘要： The present invention relates to a method, a device, and a control program for the fluid-tight sealing of capsules containing medicaments, wherein the capsules consist of at least one capsule body and a capsule cap which are set one into the other telescopically and provided with a tight band in the abutment region on the exterior side of the capsule, wherein the capsule components are filled with gas which has a changed temperature and/or a changed pressure in relation to the environment, and wherein a reduction of the difference in pressure in the capsule occurs via gaps between capsule body and capsule cap after the capsule components have been placed one inside the other. The capsules produced via the method according to the invention are disposable capsules and preferably contain a single dose of an orally administered pharmaceutical formulation in the form of a powder or a liquid.
摘要翻译：本发明涉及一种用于流体密封包含药物的胶囊的方法，装置和控制程序，其中胶囊由至少一个胶囊主体和胶囊盖组成，该胶囊主体和胶囊盖可伸缩地设置在另一个中，在胶囊的外侧上的邻接区域中具有紧密带，其中胶囊部件填充有相对于环境具有改变的温度和/或变化的压力的气体，并且其中压力差的减小在胶囊部件已经被放置在另一个内部之后，胶囊通过胶囊主体和胶囊盖之间的间隙发生。通过根据本发明的方法制备的胶囊是一次性胶囊，并且优选含有单剂量的粉末或液体形式的口服药物制剂。

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