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    • 3. 发明授权
    • Medical devices having MRI compatible metal alloys
    • 具有MRI兼容金属合金的医疗器械
    • US09327057B1
    • 2016-05-03
    • US14158444
    • 2014-01-17
    • University of Central Florida Research Foundation, Inc.
    • Rajan Vaidyanathan
    • A61L31/18A61F2/06A61L31/14A61L31/02A61N1/08
    • A61L31/022A61B10/0283A61L27/06A61L27/50A61L31/18A61L2400/12A61N1/08A61N1/086
    • An MRI compatible medical device includes a non-magnetic metal alloy portion having a bulk portion including a first and a second metal. A surface of the metal alloy portion includes an integral MRI heating resistant surface structure having a thickness ≧3 nanometers. The non-magnetic metal alloy portion is structurally different from the bulk portion and includes a lamellar nanostructure or microstructure. The MRI heating resistant surface structure can include (i) a matrix phase including the first and second metal having nanometer or micron scale particles, precipitates and/or inclusions that differ in chemical composition and physical characteristics of the matrix phase and are discontinuously distributed therein; (ii) a level of crystallinity at least 5% less than the bulk portion; and/or (iii) metal atoms different from the first and second metal having a concentration profile evidencing diffusion into the metal alloy portion.
    • MRI兼容的医疗装置包括具有包括第一和第二金属的本体部分的非磁性金属合金部分。 金属合金部分的表面包括具有≥3纳米厚度的整体MRI加热表面结构。 非磁性金属合金部分在结构上与本体部分不同,并且包括层状纳米结构或微结构。 MRI加热表面结构可以包括(i)包括具有纳米或微米级粒子的第一和第二金属的基质相,在基质相的化学组成和物理特性不同的且不连续分布的沉淀物和/或夹杂物; (ii)结晶度比本体部分少至少5%; 和/或(iii)不同于第一和第二金属的金属原子,其具有证明扩散到金属合金部分中的浓度分布。