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1. 发明授权

US11705826B2 Capacitive coupler for high voltage step-down 有权
公开(公告)号：US11705826B2
公开(公告)日：2023-07-18
申请号：US17487655
申请日：2021-09-28
申请人： Tyler D. Smith , John Patterson , Clinton W. Ewell
发明人： Tyler D. Smith , John Patterson , Clinton W. Ewell
IPC分类号： H02M7/04 , H02M7/219
CPC分类号： H02M7/05 , H02M7/219
摘要： Systems and methods for a capacitive coupler for high-voltage step-down include an actively-controlled current-steering circuit connected in series with a current-limiting capacitor in order to transform a higher and potentially variable AC voltage to a lower regulated DC voltage. The actively-controlled current-steering circuit includes a switching element which, during operation, is predominantly either fully open or fully closed, and comparatively spends only a small fraction of operating time in a transition-state between the open and closed positions.

2. 发明申请

US20220109377A1 CAPACITIVE COUPLER FOR HIGH VOLTAGE STEP-DOWN 有权
公开(公告)号：US20220109377A1
公开(公告)日：2022-04-07
申请号：US17487655
申请日：2021-09-28
申请人： Tyler D. Smith , John Patterson , Clinton W. Ewell
发明人： Tyler D. Smith , John Patterson , Clinton W. Ewell
IPC分类号： H02M7/04 , H02M7/219
摘要： Systems and methods for a capacitive coupler for high-voltage step-down include an actively-controlled current-steering circuit connected in series with a current-limiting capacitor in order to transform a higher and potentially variable AC voltage to a lower regulated DC voltage. The actively-controlled current-steering circuit includes a switching element which, during operation, is predominantly either fully open or fully closed, and comparatively spends only a small fraction of operating time in a transition-state between the open and closed positions.

3. 发明授权

US08683351B2 Chat user interface for threaded text chat systems 有权
标题翻译：用于线程文本聊天系统的聊天用户界面
公开(公告)号：US08683351B2
公开(公告)日：2014-03-25
申请号：US10973124
申请日：2004-10-26
申请人： Li-Te Cheng , Bryan W. Clark , Susanne C. Hupfer , John Patterson , Steven I. Ross
发明人： Li-Te Cheng , Bryan W. Clark , Susanne C. Hupfer , John Patterson , Steven I. Ross
IPC分类号： G06F3/00
CPC分类号： G06F3/0482 , G06Q10/107
摘要： A chat user interface for threaded text chat systems. The user interface can include a canvas view in which multiple portions of a threaded text tree for a chat session can be rendered separately and concurrently. The user interface further can include a chat participant view, a chat input view and an outline view of an ongoing chat session. Notably, selections of a threaded text tree rendered in the canvas view can be configured for zooming so that certain parts of the threaded text tree can be viewed more readily than other parts of the threaded text tree. Moreover, as new text entries are provided to any branch of the threaded text tree, visual indicators can be activated in the canvas view to alert an end user to the location of the new text entries. Finally, the canvas view can accommodate both imported external objects, such as graphics or links to Web pages, and also a white board region into which notations can be applied by an end user during the course of a chat session.
摘要翻译：用于线程文本聊天系统的聊天用户界面。用户界面可以包括画布视图，其中用于聊天会话的线程文本树的多个部分可以单独地并且同时呈现。用户界面还可以包括聊天参与者视图，聊天输入视图和正在进行的聊天会话的大纲视图。值得注意的是，可以将在画布视图中呈现的线程文本树的选择配置为缩放，以便线程文本树的某些部分可以比线程文本树的其他部分更容易查看。此外，当新文本条目提供给线程文本树的任何分支时，可以在画布视图中激活可视指示符，以向终端用户提醒新文本条目的位置。最后，画布视图可以容纳两个导入的外部对象，例如图形或到Web页面的链接，以及白板区域，在聊天会话过程中终端用户可以使用符号。

4. 发明申请

US20070142631A1 ENZYME INHIBITON IMMUNOASSAY 失效
公开(公告)号：US20070142631A1
公开(公告)日：2007-06-21
申请号：US11673180
申请日：2007-02-09
申请人： Mitali Ghoshal , Gerald Sigler , Raymond Hui , Ronald Hawley , Eva Hoess , Erasmus Huber , John Patterson , Salvatore Salamone , Allan Dorn
发明人： Mitali Ghoshal , Gerald Sigler , Raymond Hui , Ronald Hawley , Eva Hoess , Erasmus Huber , John Patterson , Salvatore Salamone , Allan Dorn
IPC分类号： C07J17/00 , C07H15/22 , C07D473/04 , C07H15/24 , C07H15/20
CPC分类号： C07D405/12 , C07D307/88 , C07D473/08 , C07H15/20 , C07H15/22 , C07H15/24 , C07J17/00 , C07J19/005 , C07J41/0005 , C07J41/0055 , C07J43/003 , G01N33/53 , G01N33/535 , G01N33/5735 , G01N33/581 , G01N33/78 , G01N33/9453 , G01N2333/904
摘要： The present invention provides a method for the measurement of an analyte in biological samples whereby an uncompetitive inhibitor is coupled to a ligand and utilized in a homogeneous assay. The analyte can be a drug or drug derivative, hormone, polypeptide, or oligonucleotide. The present invention also provides novel compounds, assay reagents and packaged kits useful for performing such measurements.
摘要翻译：本发明提供了一种用于测量生物样品中分析物的方法，由此使非竞争性抑制剂与配体偶联并用于均匀测定。分析物可以是药物或药物衍生物，激素，多肽或寡核苷酸。本发明还提供了可用于进行这种测量的新型化合物，测定试剂和包装的试剂盒。

5. 发明申请

US20070049594A1 Novel compounds and compositions as cathepsin inhibitors 审中-公开
标题翻译：新型化合物和组合物作为组织蛋白酶抑制剂
公开(公告)号：US20070049594A1
公开(公告)日：2007-03-01
申请号：US11295890
申请日：2005-12-07
申请人： Michael Graupe , John Patterson , David Aldous , Sukanthini Thurairatnam , Andreas Timm , John Link , Jiayao Li , Stephen Pickett , Frank Halley , Justine Lai
发明人： Michael Graupe , John Patterson , David Aldous , Sukanthini Thurairatnam , Andreas Timm , John Link , Jiayao Li , Stephen Pickett , Frank Halley , Justine Lai
IPC分类号： A61K31/501 , A61K31/50 , A61K31/4965 , A61K31/497 , C07D417/02 , C07D413/02
CPC分类号： C07D207/273 , A61K31/5375 , A61K31/5377 , C07C317/44 , C07C323/60 , C07D205/08 , C07D207/24 , C07D213/40 , C07D223/10 , C07D223/12 , C07D263/32 , C07D263/56 , C07D271/06 , C07D271/10 , C07D277/26 , C07D277/64 , C07D285/08 , C07D295/185 , C07D413/04 , C07D413/12 , Y02A50/411
摘要： The present invention relates to novel selective cathepsin S inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.
摘要翻译：本发明涉及新的选择性组织蛋白酶S抑制剂，其药学上可接受的盐和N-氧化物，它们作为治疗剂的用途及其制备方法。

6. 发明申请

US20070001079A1 Multi-positionable notebook computer case 有权
公开(公告)号：US20070001079A1
公开(公告)日：2007-01-04
申请号：US10646092
申请日：2003-08-22
申请人： John Patterson
发明人： John Patterson
IPC分类号： A47F5/00
CPC分类号： A45C11/00 , A45C2011/003 , G06F1/1626 , G06F2200/1633
摘要： A carrying case for an electronic device, such as a tablet personal computer, is provided, and more specifically a case that allows a user to selectively position a display screen of the tablet personal computer by rotation coupled with angular support. The case is easily adapted for use with many types and models of personal electronic devices and may be utilized to view the display screen in a plurality of orientations.

7. 发明申请

US20050288336A1 Cysteine protease inhibitors 审中-公开
标题翻译：半胱氨酸蛋白酶抑制剂
公开(公告)号：US20050288336A1
公开(公告)日：2005-12-29
申请号：US10514804
申请日：2003-05-14
申请人： Michael Graupe , Agnes Lau , John Link , Yang Liu , Craig Mossman , John Patterson , Sheila Zipfel
发明人： Michael Graupe , Agnes Lau , John Link , Yang Liu , Craig Mossman , John Patterson , Sheila Zipfel
IPC分类号： A61K31/44 , A61K31/4436 , C07D213/56 , C07D263/56 , C07D271/10 , C07D413/12 , C07D417/12 , C07D498/04
CPC分类号： C07D263/56 , C07D271/10 , C07D413/12 , C07D417/12
摘要： The present invention is directed to compounds that are inhibitors of cysteine protease, in particular, cathepsins B, K, L, F, and S and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
摘要翻译：本发明涉及半胱氨酸蛋白酶，特别是组织蛋白酶B，K，L，F和S的抑制剂的化合物，因此可用于治疗由这些蛋白酶介导的疾病。本发明涉及包含这些化合物的药物组合物及其制备方法。

8. 发明申请

US20050060644A1 Real time variable digital paper 审中-公开
标题翻译：实时可变数字纸
公开(公告)号：US20050060644A1
公开(公告)日：2005-03-17
申请号：US10925533
申请日：2004-08-25
申请人： John Patterson
发明人： John Patterson
IPC分类号： G06F3/00 , G06F17/00 , G06K9/20 , G06K9/22
CPC分类号： G06K9/2054 , G06K9/222 , G06K2009/226 , G06K2209/01
摘要： Systems and methods to convert natural input to digital information by providing variable print on demand digital paper are disclosed. The systems and methods combine form design, a digital print shop, the capture of natural input, and the interpretation and validation of the digital representation of the captured natural input to provide a robust system that can be used to populate databases as well as feed workflow and back end processes. The form design combines custom templates with field definitions and variable data overlays that are merged with position coded patterns to print unique instances of digital forms such that each instance of a document occupies a coordinate space mutually exclusive with respect to the position code coordinate space of all other documents. The interpretation, recognition and validation programs combine to create an effective conversion of handwritten information to computer recognizable meaningful format.
摘要翻译：公开了通过提供可变打印数字纸将自然输入转换为数字信息的系统和方法。系统和方法将表单设计，数字印刷商店，自然输入的捕获以及捕获的自然输入的数字表示的解释和验证相结合，以提供可用于填充数据库以及馈送工作流程的强大系统和后端处理。表单设计将自定义模板与字段定义和可变数据覆盖相结合，这些字段定义和可变数据覆盖与位置编码模式合并，以打印数字形式的独特实例，使得文档的每个实例占据相对于所有字符的位置代码坐标空间相互排斥的坐标空间其他文件。解读，识别和验证程序相结合，可以有效地将手写信息转换为计算机可识别的有意义的格式。

9. 外观设计

USD410475S Polygonal indexable cutting insert 失效
公开(公告)号：USD410475S
公开(公告)日：1999-06-01
申请号：US93395
申请日：1998-09-10
申请人： Thomas Bernadic , John Patterson , Tony Lowe , Brendan Brockett
设计人： Thomas Bernadic , John Patterson , Tony Lowe , Brendan Brockett

10. 发明授权

US5818624A Mask for viewing reduced-size radiographic film, particularly mammography film 失效
标题翻译：用于观看尺寸较小的放射照相胶片，特别是乳房X线照相胶片的面膜
公开(公告)号：US5818624A
公开(公告)日：1998-10-06
申请号：US579298
申请日：1995-12-27
申请人： John Patterson , Raynor Sturgis , Hugh Walborn , Lawrence Wilhelm
发明人： John Patterson , Raynor Sturgis , Hugh Walborn , Lawrence Wilhelm
IPC分类号： G02B27/02 , G02B26/02
CPC分类号： G02B27/024
摘要： A radiographic film mask includes a planar sheet sized for receipt on an illuminated radiographic film examination box. The mask has two opaque sections and a transparent section. The transparent section is disposed on the sheet between the two opaque sections to form a radiographic film viewing area which has an area less than the entire area of the sheet. The sheet may include semi-transparent sections which border the viewing area and interconnect the opaque portions to provide reduced transmission of light along the marginal edges of the radiographic film.
摘要翻译：射线照相胶片掩模包括尺寸适于在照射的摄影胶片检查盒上接收的平面片。面具有两个不透明部分和一个透明部分。透明部分设置在两个不透明部分之间的片材上，以形成具有小于片材整个面积的面积的射线照相胶片观看区域。片材可以包括半透明部分，其与观察区域相邻并且互连不透明部分，以提供沿着放射线照相胶片边缘的光的减少的透射。

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