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1. 发明申请

US20100261863A1 MULTIBRANCHED POLYOXYALKYLENE COMPOUND AND PRODUCING METHOD THEREOF 有权
标题翻译：多支化聚氧乙烯化合物及其制备方法
公开(公告)号：US20100261863A1
公开(公告)日：2010-10-14
申请号：US12750844
申请日：2010-03-31
申请人： Tsuyoshi TAKEHANA , Ken-ichiro NAKAMOTO , Chika ITOH
发明人： Tsuyoshi TAKEHANA , Ken-ichiro NAKAMOTO , Chika ITOH
IPC分类号： C08G65/00 , C07D207/46 , C07C69/96 , C07C255/13 , C07C209/48 , C07C217/00 , C08G63/00 , C08F20/00 , C08F26/00
CPC分类号： C08G65/33337 , A61K47/34 , C08G65/2609 , C08G65/2648 , C08G65/3322 , C08G65/3326 , C08G65/33303 , C08G65/33372 , C08G65/33389 , C08G65/3346 , C08G2650/26 , C08G2650/60
摘要： A multibranched polyoxyalkylene compound represented by the following formula (1): CH2-L1-(OA1)n-L2-X CH(OA2)mOR1 CH(OA2)mOR1 CH(OA2)mOR1 CH2(OA2)mOR1 (1) wherein R1 is the same or different and is a hydrocarbon group having 1 to 24 carbon atoms, OA1 and OA2 are the same or different and are an oxyalkylene group having 2 to 4 carbon atoms, n and m are the same or different and are an average number of moles of the oxyalkylene group added, n represents 0 to 1000, m is the same or different and represents 10 to 1000, X represents a functional group capable of reacting with an amino group, a mercapto group, an aldehyde group, a carboxyl group, a triple bond, or an azide group to form a chemical bond, and L1 and L2 are the same or different and are a single bond, an alkylene group, or an alkylene group in which at least one bond selected from an ester bond, a urethane bond, an amide bond, an ether bond, and an amino is interposed.
摘要翻译：由下式（1）表示的多分支聚氧化烯化合物：CH2-L1-（OA1）n-L2-XCH（OA2）mOR1CH（OA2）mOR1CH（OA2）mOR1 CH2（OA2）mOR1（1）相同或不同，为碳原子数为1〜24的烃基，OA1和OA2相同或不同，为碳原子数2〜4的氧化烯基，n和m相同或不同，为平均数的氧化烯基的摩尔数，n表示0〜1000，m相同或不同，表示10〜1000，X表示能够与氨基，巯基，醛基，羧基反应的官能团，三键或叠氮基以形成化学键，并且L1和L2相同或不同，为单键，亚烷基或亚烷基，其中至少一个选自酯键，氨基甲酸酯键，酰胺键，醚键和氨基。

2. 发明申请

US20100286361A1 PURIFICATION METHOD OF HIGH-MOLECULAR-WEIGHT POLYOXYALKYLENE DERIVATIVE 有权
标题翻译：高分子量聚氧乙烯衍生物的纯化方法
公开(公告)号：US20100286361A1
公开(公告)日：2010-11-11
申请号：US12750842
申请日：2010-03-31
申请人： Shuichi YOSHIMURA , Ken-ichiro NAKAMOTO , Chika ITOH
发明人： Shuichi YOSHIMURA , Ken-ichiro NAKAMOTO , Chika ITOH
IPC分类号： C08F6/28
CPC分类号： C08G65/30 , C08G65/329 , C08L2203/02
摘要： A purification method in which, from a specific polyoxyalkylene derivative having a molecular weight of 8,800 to 100,000, an impurity differing in the number of hydroxyl groups is separated, the method including steps (A), (B), (C), and (D). Step (A): a step in which an aprotic organic solvent is used in an amount at least 5 times by weight the amount of the polyoxyalkylene derivative to dissolve the polyoxyalkylene derivative therein and give a solution; step (B): a step in which an adsorbent comprising an oxide containing at least one of aluminum and silicon is added to the solution in an amount 0.5 to 5 times by weight the amount of the polyoxyalkylene derivative to thereby yield a slurry; step (C): a step in which the slurry is stirred at 25° C. or higher; step (D): a step in which the polyoxyalkylene derivative is recovered from the slurry.
摘要翻译：一种纯化方法，其特征在于，分子量为8,800〜100,000的特定的聚氧亚烷基衍生物分离出羟基数不同的杂质，包括步骤（A），（B），（C）和（C） D）。步骤（A）：使非质子性有机溶剂的使用量为聚氧亚烷基衍生物的量的至少5倍以溶解其中的聚氧化烯衍生物并得到溶液的步骤; 步骤（B）：将含有铝和硅中的至少一种的氧化物的吸附剂以0.5〜5倍量的量添加到溶液中，从而得到浆料的步骤; 步骤（C）：将浆料在25℃以上搅拌的步骤; 步骤（D）：从浆料中回收聚氧化烯衍生物的步骤。

3. 发明申请

US20100256423A1 METHOD FOR PRODUCING POLYOXYALKYLENE DERIVATIVE AND POLYOXYALKYLENE DERIVATIVE 有权
标题翻译：生产聚羟基甲基衍生物和聚氧乙烯衍生物的方法
公开(公告)号：US20100256423A1
公开(公告)日：2010-10-07
申请号：US12751150
申请日：2010-03-31
申请人： Satoshi MATSUO , Kazuhiro HASHIMOTO , Ken-ichiro NAKAMOTO , Chika ITOH
发明人： Satoshi MATSUO , Kazuhiro HASHIMOTO , Ken-ichiro NAKAMOTO , Chika ITOH
IPC分类号： C07C43/03 , C07C41/09
CPC分类号： C08G65/2609 , C08G65/2696
摘要： A method for producing a polyoxyalkylene derivative represented by the following general formula (1): Z(OA)n—OH]m (1) wherein Z is a residue of glycerin or diglycerin, OA is an oxyalkylene group having 2 to 4 carbon atoms, n is an average number of moles of the oxyalkylene group added and is 80 to 800, and m is 3 to 4,the method comprising steps (A), (B), (C), (D), (E), and (F) defined in the present description.
摘要翻译：制备由以下通式（1）表示的聚氧化烯衍生物的方法：Z（OA）n-OH] m（1）其中Z是甘油或二甘油的残基，OA是具有2至4个碳的氧化烯基原子，n是加成的氧化烯基的平均摩尔数，为80〜800，m为3〜4，该方法包括（A），（B），（C），（D），（E），和（F）在本说明书中定义。

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