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1. 发明申请

US20090270189A1 Dynamic Damper 有权
标题翻译：动态阻尼器
公开(公告)号：US20090270189A1
公开(公告)日：2009-10-29
申请号：US11992197
申请日：2006-09-21
申请人： Tsutomu Kawakatsu , Shouichi Nakao , Susumu Suzuki , Takao Kurihara
发明人： Tsutomu Kawakatsu , Shouichi Nakao , Susumu Suzuki , Takao Kurihara
IPC分类号： F16F15/10 , F16F15/12 , F16F7/00
CPC分类号： F16F15/1442 , Y10T464/50
摘要： A dynamic damper in which the inner diameter (D2) of a first hole part formed at the axial one end part of a body part overlapped with a weight part in the radial direction is set smaller than the inner diameter (D3) of a second hole part formed at the axial other end part of the body part not overlapped with the weight part in the radial direction and tightened with a band member (D3>D2). The outer diameter (D1) of a drive shaft to be press-fitted into the first and second hole parts is set larger than the inner diameter (D2) of the first hole part and the inner diameter (D3) of the second hole part (D1>D3>D2).
摘要翻译：一种动力阻尼器，其中形成在与径向重叠部分重叠的主体部分的轴向一端部处的第一孔部的内径（D2）设定为小于第二孔的内径（D3）形成在主体部分的轴向另一端部处的部分不与重量部分在径向方向上重叠并且用带部件（D3> D2）紧固。压入第一孔部和第二孔部的驱动轴的外径（D1）被设定为大于第一孔部的内径（D2）和第二孔部的内径（D3） D1> D3> D2）。

2. 发明授权

US07946925B2 Dynamic damper 有权
标题翻译：动态阻尼器
公开(公告)号：US07946925B2
公开(公告)日：2011-05-24
申请号：US11992197
申请日：2006-09-21
申请人： Tsutomu Kawakatsu , Shouichi Nakao , Susumu Suzuki , Takao Kurihara
发明人： Tsutomu Kawakatsu , Shouichi Nakao , Susumu Suzuki , Takao Kurihara
IPC分类号： F16F7/104
CPC分类号： F16F15/1442 , Y10T464/50
摘要： A dynamic damper in which the inner diameter (D2) of a first hole part formed at the axial one end part of a body part overlapped with a weight part in the radial direction is set smaller than the inner diameter (D3) of a second hole part formed at the axial other end part of the body part not overlapped with the weight part in the radial direction and tightened with a band member (D3>D2). The outer diameter (D1) of a drive shaft to be press-fitted into the first and second hole parts is set larger than the inner diameter (D2) of the first hole part and the inner diameter (D3) of the second hole part (D1>D3>D2).
摘要翻译：一种动力阻尼器，其中形成在与径向重叠部分重叠的主体部分的轴向一端部处的第一孔部的内径（D2）设定为小于第二孔的内径（D3）形成在主体部分的轴向另一端部处的部分不与重量部分在径向方向上重叠并且用带部件（D3> D2）紧固。压入第一孔部和第二孔部的驱动轴的外径（D1）被设定为大于第一孔部的内径（D2）和第二孔部的内径（D3） D1> D3> D2）。

3. 发明授权

US07718403B2 Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process 有权
标题翻译：通过DNA聚合过程产生的全基因组和整个转录组文库的扩增和分析
公开(公告)号：US07718403B2
公开(公告)日：2010-05-18
申请号：US10795667
申请日：2004-03-08
申请人： Emmanuel Kamberov , Tong Sun , Eric Bruening , Jonathon H. Pinter , Irina Sleptsova , Takao Kurihara , Vladimir L. Makarov
发明人： Emmanuel Kamberov , Tong Sun , Eric Bruening , Jonathon H. Pinter , Irina Sleptsova , Takao Kurihara , Vladimir L. Makarov
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12N15/1093 , C12N15/10 , C12Q1/686 , C40B40/06 , C40B50/06 , C12Q2525/161 , C12Q2525/179 , C12Q2525/15
摘要： The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
摘要翻译：本发明涉及用于全基因组扩增和全转录组扩增的多种方法和组合物。在本发明的特定方面，存在扩增包含文库产生步骤之后是文库扩增步骤的基因组的方法。在具体实施方案中，文库产生步骤使用特异性引物混合物和DNA聚合酶，其中特异性引物混合物被设计为消除混合物内其它引物自我杂交和/或杂交的能力，但有效且频繁引发核酸模板。

4. 发明授权

US5285471A Spread spectrum receiving device 失效
标题翻译：扩频接收装置
公开(公告)号：US5285471A
公开(公告)日：1994-02-08
申请号：US993378
申请日：1992-12-18
申请人： Takao Kurihara
发明人： Takao Kurihara
IPC分类号： H04B1/707 , H04L27/30 , H03D3/18 , H04L27/06
CPC分类号： H04B1/709 , H04B1/707
摘要： A spread spectrum receiving device is disclosed, in which data demodulation is effected in such a way that a received signal is divided into two parts, from which a COS PN code chip signal and a SIN PN code chip signal are obtained; that these chip signals are A/D-converted by means of A/D converters and then given to digital correlators; and that correlation outputs thus obtained are combined to synthesize a final correlation output. Further there are disposed a plurality of steering gates on the input side of the A/D converters. The a/D conversion can be effected in the neighborhood of a point, where the level of PN code chip waveforms is stable, owing to the fact that the steering gates are controlled by control signals obtained by processing the correlation outputs or output of the A/D conversion. In this way it is made unnecessary to raise the sampling frequency for the A/D conversion and to increase the number of stages of shift registers in the digital correlators.
摘要翻译：公开了一种扩展频谱接收装置，其中以这样一种方式实现数据解调，使得接收信号被分成两部分，从中获得COS PN码片信号和SIN PN码片信号; 这些芯片信号通过A / D转换器进行A / D转换，然后给予数字相关器; 并且将由此获得的相关输出组合以合成最终的相关输出。此外，在A / D转换器的输入侧设置多个转向门。由于通过处理A相关输出或输出的相关输出或输出获得的控制信号来控制转向门，因此可以在PN码片波形的电平稳定的点附近实现a / D转换 / D转换。以这种方式，不必提高A / D转换的采样频率并增加数字相关器中的移位寄存器的级数。

5. 发明申请

US20050202490A1 Methods and compositions for generating and amplifying DNA libraries for sensitive detection and analysis of DNA methylation 有权
标题翻译：用于产生和扩增DNA文库以灵敏检测和分析DNA甲基化的方法和组合物
公开(公告)号：US20050202490A1
公开(公告)日：2005-09-15
申请号：US11071864
申请日：2005-03-03
申请人： Vladimir Makarov , Emmanuel Kamberov , Tong Sun , Jonathon Pinter , Brendan Tarrier , Eric Bruening , Takao Kurihara , Tim Tesmer , Joseph M'Mwirichia
发明人： Vladimir Makarov , Emmanuel Kamberov , Tong Sun , Jonathon Pinter , Brendan Tarrier , Eric Bruening , Takao Kurihara , Tim Tesmer , Joseph M'Mwirichia
IPC分类号： C12N15/10 , C12P19/34 , C12Q1/68
CPC分类号： C12Q1/6869 , C12N15/1072 , C12Q1/6827 , C12Q1/6855 , C12Q2525/301 , C12Q2525/191 , C12Q2521/331 , C12Q2523/125
摘要： The present invention regards a variety of methods and compositions for obtaining epigenetic information, such as DNA methylation patterns, through the preparation, amplification and analysis of Methylome libraries. In several aspects of the present invention, there are methods based on methylation-dependent enrichment or depletion of genomic DNA isolated from cellular and cell-free sources. In additional embodiments, there are methods and compositions for single-step high throughput preparations of Methylome libraries.
摘要翻译：本发明涉及通过Methylome文库的制备，扩增和分析来获得表观遗传信息的各种方法和组合物，例如DNA甲基化模式。在本发明的几个方面，存在基于从细胞和无细胞来源分离的基因组DNA的甲基化依赖性富集或消耗的方法。在另外的实施方案中，存在Methylome文库的单步高通量制剂的方法和组合物。

6. 发明授权

US5157689A GOLD code generating device in a spread spectrum communication device 失效
标题翻译： GOLD码产生装置在扩频通信装置中
公开(公告)号：US5157689A
公开(公告)日：1992-10-20
申请号：US751819
申请日：1991-08-30
申请人： Takao Kurihara
发明人： Takao Kurihara
IPC分类号： H03K3/84 , G06F7/58 , H04J13/00 , H04J13/10
CPC分类号： H04J13/10 , G06F7/584 , H04B1/707 , H04J13/0029
摘要： A GOLD code generating device in an SSC device is disclosed, which is so constructed that, in the case where two kinds of GOLD codes are used in the SSC device by the CSK system, etc., in order to generate a GOLD code by means of two m sequence codes, a first GOLD code is generated by using an m sequence code generated by one of the m sequence code generators and another m sequence code generated by the other m sequence code generator, while a second GOLD code is generated by using an m sequence code obtained by delaying the m sequence code generated by the other m sequence code generator by a predetermined number of chips.
摘要翻译：公开了一种SSC装置中的GOLD代码生成装置，其结构是，在通过CSK系统等在SSC装置中使用两种GOLD代码的情况下，为了通过装置生成GOLD代码通过使用由m个序列码发生器中的一个生成的m个序列码和由另一个m序列码发生器产生的另一个m序列码产生第一个GOLD码，而通过使用第二个GOLD码生成第二个GOLD码通过将由另一个m序列码发生器产生的m个序列码延迟预定数量的码片而获得的m序列码。

7. 发明授权

US5128998A Head or arbitrary bit pulse generating circuit and sampling pulse generating circuit in a pseudo noise code generator 失效
标题翻译：头或任意位脉冲发生电路和伪噪声码发生器中的采样脉冲发生电路
公开(公告)号：US5128998A
公开(公告)日：1992-07-07
申请号：US585911
申请日：1990-09-21
申请人： Takao Kurihara
发明人： Takao Kurihara
IPC分类号： H03K3/84 , H04J13/00 , H04J13/10
CPC分类号： H04J13/0022 , H03K3/84 , H04J13/10
摘要： A pseudo noise code generator is disclosed, in which the shift register value of the pseudo noise code generator corresponding to the generation timing of a bit pulse or a sampling pulse is latched and the output of the latch is compared with the shift register value of the generator, the bit pulse or the sampling pulse being obtained, when they are in accordance with each other.
摘要翻译：公开了一种伪噪声码发生器，其中锁存与位脉冲或采样脉冲的生成定时对应的伪噪声码发生器的移位寄存器值，并将锁存器的输出与发生器，当它们彼此相符时获得位脉冲或采样脉冲。

8. 发明授权

US4943975A Spread spectrum communication receiver 失效
标题翻译：扩频通信接收机
公开(公告)号：US4943975A
公开(公告)日：1990-07-24
申请号：US256394
申请日：1988-10-07
申请人： Takao Kurihara , Masahiro Hamatsu , Masaharu Mori
发明人： Takao Kurihara , Masahiro Hamatsu , Masaharu Mori
IPC分类号： H04B1/707
CPC分类号： H04B1/7093 , H04B1/70712
摘要： A spread spectrum communication receiver is disclosed, which is provided with a correlator for correlating a received PN code contained in a received signal with a reference PN code contained in a reference signal generated on the receiver side, the output of which is given to pattern judgment means such as a matched filter, etc., and an operation of the initial synchronization of the two PN codes in the correlator is effected by using a judgment output obtained when the pattern of the output of the correlator is in accordance with a predetermined judgment pattern.
摘要翻译：公开了一种扩展频谱通信接收机，其具有相关器，用于将包含在接收信号中的接收PN码与包含在接收机侧产生的参考信号中的参考PN码进行相关，该参考信号的输出被提供给模式判断诸如匹配滤波器等的装置，并且通过使用当相关器的输出的图案符合预定的判断模式时获得的判断输出来实现相关器中的两个PN码的初始同步的操作。

9. 发明授权

US4864525A Maximum length shift register sequence generator 失效
标题翻译：最大长度移位寄存器序列发生器
公开(公告)号：US4864525A
公开(公告)日：1989-09-05
申请号：US70491
申请日：1987-07-07
申请人： Takao Kurihara , Masahiro Hamatsu
发明人： Takao Kurihara , Masahiro Hamatsu
IPC分类号： H03K3/84 , H04L9/22
CPC分类号： H03K3/84 , H04L9/0662 , H04L2209/12
摘要： A maximum length shift register sequence generator comprises: (1) an input terminal for feedback (FB 0); (2) an input terminal to the steering gate of the first stage (FB 1); (3) an output terminal from the exclusive OR gate of the last stage (CAS); (4) a three state output terminal from a multiplexer circuit (FB 2); and (5) a control input terminal of a three state output multiplexer circuit (FBCNT); a plurality of which can be connected in cascade. It includes a flipflop circuit, whose data input is a feedback control signal (FBCNT) controlling within which maximum length shift register sequence generator the output of the multiplexer circuit should be fedback, when they are connected in cascade, and whose clock input is the strobe pulse (STB), the output of this flipflop circuit being the enable input of the three state output multiplexer circuit. It includes further a logical product gate (AND 0), whose inputs are two signals, one being a latch enable pulse ( LE ) for latching, (i) the initial state of the flipflop, (ii) the feedback state, (iii) the last stage selection state for the flipflops, the other being a chip select (CS), and a demultiplexer circuit distributing the output of this logical product gate (AND 0) to the latch circuits for latching the data (i).about.(iii) described above, depending on the two select signals (SEL 0.about.1).
摘要翻译：最大长度移位寄存器序列发生器包括：（1）用于反馈的输入端（FB 0）; （2）到第一级（FB 1）的转向门的输入端子; （3）来自最后级的异或门的输出端子（CAS）; （4）来自多路复用器电路（FB2）的三态输出端子; 和（5）三状态输出多路复用器电路（＆upbar＆F）的控制输入端子; 其多个可以级联连接。它包括一个触发器电路，其数据输入是一个反馈控制信号（＆amp; upbar＆F），控制其中最大长度移位寄存器序列发生器，多路复用器电路的输出应该反馈，当它们串联连接时，其时钟输入为选通脉冲（STB），该触发电路的输出是三态输出多路复用器电路的使能输入。它还包括逻辑积门（AND 0），其输入是两个信号，一个是用于锁存的锁存使能脉冲（LE），（i）触发器的初始状态，（ii）反馈状态，（iii）触发器的最后阶段选择状态，另一个是芯片选择（＆amp; upbar＆amp; C），以及将该逻辑积门（AND 0）的输出分配给锁存电路的解复用器电路，用于锁存数据（i）DIFFERENCE ），这取决于两个选择信号（SEL 0 DIFFERENCE 1）。

10. 发明申请

US20070054311A1 Amplification and analysis of whole genome and whole transcriptome libraries generated by a DNA polymerization process 审中-公开
标题翻译：通过DNA聚合过程产生的全基因组和整个转录组文库的扩增和分析
公开(公告)号：US20070054311A1
公开(公告)日：2007-03-08
申请号：US11593625
申请日：2006-11-06
申请人： Emmanuel Kamberov , Tong Sun , Eric Bruening , Jonathon Pinter , Irina Sleptsova , Takao Kurihara , Vladimir Makarov
发明人： Emmanuel Kamberov , Tong Sun , Eric Bruening , Jonathon Pinter , Irina Sleptsova , Takao Kurihara , Vladimir Makarov
IPC分类号： C12Q1/68 , C12P19/34
CPC分类号： C12N15/1093 , C12N15/10 , C12Q1/686 , C40B40/06 , C40B50/06 , C12Q2525/161 , C12Q2525/179 , C12Q2525/15
摘要： The present invention regards a variety of methods and compositions for whole genome amplification and whole transcriptome amplification. In a particular aspect of the present invention, there is a method of amplifying a genome comprising a library generation step followed by a library amplification step. In specific embodiments, the library generating step utilizes specific primer mixtures and a DNA polymerase, wherein the specific primer mixtures are designed to eliminate ability to self-hybridize and/or hybridize to other primers within a mixture but efficiently and frequently prime nucleic acid templates.
摘要翻译：本发明涉及用于全基因组扩增和全转录组扩增的多种方法和组合物。在本发明的特定方面，存在扩增包含文库产生步骤之后是文库扩增步骤的基因组的方法。在具体实施方案中，文库产生步骤使用特异性引物混合物和DNA聚合酶，其中特异性引物混合物被设计为消除混合物内其它引物自我杂交和/或杂交的能力，但有效且频繁引发核酸模板。

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