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1. 发明授权

US06841374B1 Enhanced immunogen for inactivated vaccine for infection with Japanese encephalitis viruses and process for producing the same 失效
标题翻译：用于日本脑炎病毒感染的灭活疫苗的增强免疫原及其生产方法
公开(公告)号：US06841374B1
公开(公告)日：2005-01-11
申请号：US09555704
申请日：1999-06-02
申请人： Toyokazu Ishikawa , Hironori Yoshii , Toshiyuki Onishi , Tadashi Imagawa , Masahide Ishibashi
发明人： Toyokazu Ishikawa , Hironori Yoshii , Toshiyuki Onishi , Tadashi Imagawa , Masahide Ishibashi
IPC分类号： A61K39/12 , C12N7/02 , C12N7/06
CPC分类号： C12N7/00 , A61K39/12 , A61K2039/5252 , A61K2039/70 , C12N2770/24134 , C12N2770/24151 , C12N2770/24163 , Y02A50/39
摘要： The present invention provides a novel inactivated virus particle and a reinforced immunogen which have a reinforced titer about twice to about 10 times that of a conventional vaccine, as well as a method for producing the same. The inactivated virus particle is produced by inactivating and then purifying a culture by physical means. The inactivated virus particle of the present invention is useful in a diagnostic agent for infectious disease caused by a group of Japanese encephalitis virus.
摘要翻译：本发明提供了一种新型灭活病毒颗粒和增强免疫原，其具有约为常规疫苗的约2倍至约10倍的增强滴度，以及其制备方法。灭活的病毒颗粒是通过灭活然后通过物理方法纯化培养物产生的。本发明的灭活病毒颗粒可用于由一组日本脑炎病毒引起的感染性疾病的诊断剂。

2. 发明授权

US08492532B2 Attenuated chimeric flavivirus bearing attenuated japanese encephalitis virus gene as backbone 失效
标题翻译：减毒的日本脑炎病毒基因的减毒嵌合黄病毒为骨架
公开(公告)号：US08492532B2
公开(公告)日：2013-07-23
申请号：US12292518
申请日：2008-11-20
申请人： Kouichi Morita , Takeshi Nabeshima , Shinichi Miyake , Toshiyuki Onishi , Isao Fuke , Toyokazu Ishikawa , Hideo Goda , Masahide Ishibashi , Michiaki Takahashi
发明人： Kouichi Morita , Takeshi Nabeshima , Shinichi Miyake , Toshiyuki Onishi , Isao Fuke , Toyokazu Ishikawa , Hideo Goda , Masahide Ishibashi , Michiaki Takahashi
IPC分类号： C12N7/00 , A61K39/12
CPC分类号： A61K39/12 , A61K2039/5254 , C12N7/00 , C12N2770/24134 , C12N2770/24161 , Y02A50/386 , Y02A50/388 , Y02A50/39 , Y02A50/394 , Y02A50/396
摘要： A nucleic acid molecule containing nucleotide sequences that encode the capsid protein, pre-membrane protein and non-structural protein of Japanese encephalitis virus, and a nucleotide sequence that encodes the envelop protein of a second flavivirus, wherein the nucleotide sequence(s) that encode(s) the pre-membrane protein and/or non-structural protein of Japanese encephalitis virus contain(s) nucleotide mutations that produce one or more amino acid mutations that attenuate the virus.
摘要翻译：含有编码日本脑炎病毒的衣壳蛋白，膜前蛋白质和非结构蛋白质的核苷酸序列的核酸分子和编码第二黄病毒的包膜蛋白的核苷酸序列，其中编码的核苷酸序列日本脑炎病毒的膜前蛋白质和/或非结构蛋白质含有产生一种或多种减弱病毒的氨基酸突变的核苷酸突变。

3. 发明申请

US20090104702A1 Attenuated chimeric flavivirus bearing attenuated Japanese encephalitis virus gene as backbone 失效
标题翻译：具有减毒的日本脑炎病毒基因的减毒嵌合黄病毒作为骨架
公开(公告)号：US20090104702A1
公开(公告)日：2009-04-23
申请号：US12292518
申请日：2008-11-20
申请人： Morita Kouichi , Takeshi Nabeshima , Shinichi Miyake , Toshiyuki Onishi , Isao Fuke , Toyokazu Ishikawa , Hideo Goda , Masahide Ishibashi , Michiaki Takahashi
发明人： Morita Kouichi , Takeshi Nabeshima , Shinichi Miyake , Toshiyuki Onishi , Isao Fuke , Toyokazu Ishikawa , Hideo Goda , Masahide Ishibashi , Michiaki Takahashi
IPC分类号： C12N15/87 , C12N15/11 , C12N15/00 , C12N7/00
CPC分类号： A61K39/12 , A61K2039/5254 , C12N7/00 , C12N2770/24134 , C12N2770/24161 , Y02A50/386 , Y02A50/388 , Y02A50/39 , Y02A50/394 , Y02A50/396
摘要： A nucleic acid molecule containing nucleotide sequences that encode the capsid protein, pre-membrane protein and non-structural protein of Japanese encephalitis virus, and a nucleotide sequence that encodes the envelop protein of a second flavivirus, wherein the nucleotide sequence(s) that encode(s) the pre-membrane protein and/or non-structural protein of Japanese encephalitis virus contain(s) nucleotide mutations that produce one or more amino acid mutations that attenuate the virus.
摘要翻译：含有编码日本脑炎病毒的衣壳蛋白，膜前蛋白质和非结构蛋白质的核苷酸序列的核酸分子和编码第二黄病毒的包膜蛋白的核苷酸序列，其中编码的核苷酸序列日本脑炎病毒的膜前蛋白质和/或非结构蛋白质含有产生一种或多种减弱病毒的氨基酸突变的核苷酸突变。

4. 发明授权

US07749734B2 Attenuated chimeric flavivirus bearing attenuated Japanese encephalitis virus gene as backbone 失效
标题翻译：具有减毒的日本脑炎病毒基因的减毒嵌合黄病毒作为骨架
公开(公告)号：US07749734B2
公开(公告)日：2010-07-06
申请号：US11793277
申请日：2005-12-22
申请人： Morita Kouichi , Takeshi Nabeshima , Shinichi Miyake , Toshiyuki Onishi , Isao Fuke , Toyokazu Ishikawa , Hideo Goda , Masahide Ishibashi , Michiaki Takahashi
发明人： Morita Kouichi , Takeshi Nabeshima , Shinichi Miyake , Toshiyuki Onishi , Isao Fuke , Toyokazu Ishikawa , Hideo Goda , Masahide Ishibashi , Michiaki Takahashi
IPC分类号： C12N7/01 , A61K39/12
CPC分类号： A61K39/12 , A61K2039/5254 , C12N7/00 , C12N2770/24134 , C12N2770/24161 , Y02A50/386 , Y02A50/388 , Y02A50/39 , Y02A50/394 , Y02A50/396
摘要： A nucleic acid molecule containing nucleotide sequences that encode the capsid protein, pre-membrane protein and non-structural protein of Japanese encephalitis virus, and a nucleotide sequence that encodes the envelop protein of a second flavivirus, wherein the nucleotide sequence(s) that encode(s) the pre-membrane protein and/or non-structural protein of Japanese encephalitis virus contain(s) nucleotide mutations that produce one or more amino acid mutations that attenuate the virus.
摘要翻译：含有编码日本脑炎病毒的衣壳蛋白，膜前蛋白质和非结构蛋白质的核苷酸序列的核酸分子和编码第二黄病毒的包膜蛋白的核苷酸序列，其中编码的核苷酸序列日本脑炎病毒的膜前蛋白质和/或非结构蛋白质含有产生一种或多种减弱病毒的氨基酸突变的核苷酸突变。

5. 发明申请

US20090022643A1 SO3 REDUCTION CATALYST FOR PURIFYING AN EXHAUST GAS, PREPARATION PROCESS THEREOF, AND EXHAUST GAS PURIFYING METHOD USING THE CATALYST 审中-公开
标题翻译：用于净化排气的SO3还原催化剂，其制备方法和使用催化剂的排气净化方法
公开(公告)号：US20090022643A1
公开(公告)日：2009-01-22
申请号：US11908902
申请日：2005-04-06
申请人： Katsumi Nochi , Masanao Yonemura , Kozo Iida , Yoshiaki Obayashi , Shigeru Nojima , Toshiyuki Onishi
发明人： Katsumi Nochi , Masanao Yonemura , Kozo Iida , Yoshiaki Obayashi , Shigeru Nojima , Toshiyuki Onishi
IPC分类号： B01D53/50 , B01J23/46 , B01J21/08 , B01J27/25 , B01J27/10 , B01J27/08 , B01J27/053 , B01J27/24 , B01J31/12 , B01J23/28 , B01J23/30 , B32B3/12
CPC分类号： B01D53/8628 , B01D53/8609 , B01J21/063 , B01J21/066 , B01J23/46 , B01J23/462 , B01J23/468 , B01J23/652 , B01J23/6525 , B01J23/6527 , B01J35/0073 , B01J35/04 , B01J37/0211 , Y10T428/24149
摘要： To provide an SO3 reduction catalyst for purifying an exhaust gas capable of efficiently reducing the amount of SO3 that is present in a combustion exhaust gas and is a starting substance of S-containing substances such as acid ammonium sulfate causing deterioration of performance of the catalyst or corrosion of apparatuses disposed downstream of the catalyst, or capable of controlling the generation of SO3 in the catalyst itself; a preparation process of the catalyst; and an exhaust gas purifying method using the catalyst.In the catalyst for purifying a combustion exhaust gas containing nitrogen oxides, 50 wt. % or greater of the amount of Ru and/or Ir to be supported is adjusted to fall within a depth of 150 μm from the surface layer of a substrate; and the catalyst is prepared by immersing the substrate in a metal colloid solution of Ru and/or Ir to be supported or an aqueous solution containing at least one compound selected from compounds of Ru and/or Ir to be supported.
摘要翻译：提供一种用于净化排气的SO 3还原催化剂，其能够有效地减少燃烧废气中存在的SO 3的量，并且是含有S的物质如酸式硫酸铵的起始物质，导致催化剂的性能降低，或者设置在催化剂下游的装置的腐蚀，或能够控制催化剂本身中SO 3的产生; 催化剂的制备方法; 和使用该催化剂的排气净化方法。在用于净化含有氮氧化物的燃烧废气的催化剂中，要负载的Ru和/或Ir的量的％或更多的量被调节为落在离衬底的表面层150μm的深度内; 并将催化剂浸渍在待负载的Ru和/或Ir的金属胶体溶液中，或含有至少一种选自待负载的Ru和/或Ir化合物的化合物的水溶液中。

6. 发明授权

US07241255B2 Method and apparatus for attaching a hook-and-loop fastener to a carton with a lid 失效
标题翻译：用于将钩环紧固件附接到具有盖的纸箱的方法和装置
公开(公告)号：US07241255B2
公开(公告)日：2007-07-10
申请号：US11187485
申请日：2005-07-22
申请人： Toshiyuki Onishi
发明人： Toshiyuki Onishi
IPC分类号： B31B1/90
CPC分类号： B31B50/00 , B31B50/8144 , B65D2313/02
摘要： A pair of hook-and-loop fasteners are attached onto a carton for securing a lid thereof. First fasteners are provided spaced apart along a first exfoliation sheet. Second fasteners adapted to mate and engage with the first fasteners are provided spaced apart along a second exfoliation sheet. The first sheet is deflected over a first knife edge to peel-off a first fastener and engage it onto a second fastener to form a fastener pair. The second sheet is deflected over a second knife edge to peel-off the second fastener of the pair from the second sheet and adhesively stick the fastener pair onto the carton.
摘要翻译：一对钩环紧固件被附接到纸箱上以固定其盖。第一紧固件沿着第一剥离片隔开设置。适于与第一紧固件配合和接合的第二紧固件沿第二剥离片隔开设置。第一片材偏转在第一刀刃上以剥离第一紧固件并将其接合到第二紧固件上以形成紧固件对。第二片材在第二刀刃上偏转以将该对的第二紧固件与第二片材剥离，并将紧固件对粘合到纸箱上。

7. 发明申请

US20070021284A1 Method and apparatus for attaching a hook-and-loop fastener to a carton with a lid 失效
公开(公告)号：US20070021284A1
公开(公告)日：2007-01-25
申请号：US11187485
申请日：2005-07-22
申请人： Toshiyuki Onishi
发明人： Toshiyuki Onishi
IPC分类号： B31B1/00
CPC分类号： B31B50/00 , B31B50/8144 , B65D2313/02
摘要： A pair of hook-and-loop fasteners are attached onto a carton for securing a lid thereof. First fasteners are provided spaced apart along a first exfoliation sheet. Second fasteners adapted to mate and engage with the first fasteners are provided spaced apart along a second exfoliation sheet. The first sheet is deflected over a first knife edge to peel-off a first fastener and engage it onto a second fastener to form a fastener pair. The second sheet is deflected over a second knife edge to peel-off the second fastener of the pair from the second sheet and adhesively stick the fastener pair onto the carton.

8. 发明授权

US06868294B2 Feedback control method in V-shaped characteristic system, and NH3 injection rate control method for NOx removal apparatus using the same 有权
标题翻译： V型特征系统中的反馈控制方法，以及使用其的NOx去除装置的NH 3注入速率控制方法
公开(公告)号：US06868294B2
公开(公告)日：2005-03-15
申请号：US10337828
申请日：2003-01-08
申请人： Susumu Kouno , Kenji Suzuki , Kazuko Takeshita , Kozo Iida , Toshiyuki Onishi , Akira Hattori
发明人： Susumu Kouno , Kenji Suzuki , Kazuko Takeshita , Kozo Iida , Toshiyuki Onishi , Akira Hattori
IPC分类号： F01N3/08 , B01D53/34 , B01D53/56 , B01D53/74 , B01D53/86 , B01D53/90 , B01D53/94 , G05B13/02
CPC分类号： B01D53/8631 , B01D53/90
摘要： In the NH3 injection rate control method for an NOx removal apparatus, operating area of the apparatus is divided into first area in which molar ratio of NH3 injection rate with respect to NOx flow rate at an inlet of the apparatus is smaller than molar ratio at minimum point where NOx concentration assumes minimum value and second area in which the molar ratio is equal to or larger than the minimum point molar ratio, and virtual NOx concentration with respect to the molar ratio is set according to virtual characteristic line which varies monotonically to stride across desired operating point without rising with increase of the molar ratio from the first area to the second area. Moreover, feedback control is implemented for adjusting the NH3 injection rate with respect to the NOx flow rate in direction that the virtual NOx concentration is brought close to the desired NOx concentration.
摘要翻译：在用于NOx去除装置的NH 3注入速率控制方法中，装置的操作区域被划分为第一区域，其中NH 3注入速率相对于装置入口处的NOx流量的摩尔比最小的摩尔比 NOx浓度为最小值的点和摩尔比等于或大于最小点摩尔比的第二区域，并且根据摩尔比的虚拟NOx浓度根据单调变化以跨越的虚拟特征线来设定所需工作点不随着从第一区域到第二区域的摩尔比的增加而上升。此外，实施反馈控制，以使虚拟NOx浓度接近期望的NOx浓度的方向相对于NOx流量调节NH 3注入速率。

9. 发明授权

US06412934B1 Ink jet printing method and apparatus 失效
标题翻译：喷墨打印方法和装置
公开(公告)号：US06412934B1
公开(公告)日：2002-07-02
申请号：US08511230
申请日：1995-08-04
申请人： Jiro Moriyama , Toshiyuki Onishi , Hiroshi Tajika , Toshiharu Inui , Hitoshi Sugimoto , Kiichiro Takahashi , Masao Kato , Minako Kato
发明人： Jiro Moriyama , Toshiyuki Onishi , Hiroshi Tajika , Toshiharu Inui , Hitoshi Sugimoto , Kiichiro Takahashi , Masao Kato , Minako Kato
IPC分类号： B41J217
CPC分类号： B41J2/2114
摘要： An ink jet printing method uses an ink jet ejecting portion for ejecting ink on a printing material and a print quality improving liquid ejecting portion for ejecting print quality improving liquid on the printing material. The application mode of the print quality improving liquid is different depending on the printing mode in which a printing operation is carried out.
摘要翻译：喷墨打印方法使用用于在打印材料上喷射油墨的喷墨喷射部分和用于在打印材料上喷射打印质量改进液体的打印质量改进液体喷射部分。打印质量改进液体的应用模式根据执行打印操作的打印模式而不同。

10. 发明授权

US06238172B1 Empty case centering device for a disk packaging apparatus 失效
标题翻译：用于盘包装设备的空盒定心装置
公开(公告)号：US06238172B1
公开(公告)日：2001-05-29
申请号：US09384492
申请日：1999-08-27
申请人： Toshiyuki Onishi
发明人： Toshiyuki Onishi
IPC分类号： B65B2524
CPC分类号： B65B43/54
摘要： An apparatus for positioning a case to be loaded with an optical disk, includes a pair of slide plates slidable in opposite, horizontal directions for moving a pair of positioning members (5A, 5B) rotatably connected to the ends of the slide plates. The positioning members are moved between a withdrawn rest position in which toe faces (6a) of the positioning members (5A, 5B) do not contact the case, and a locating position wherein the toe faces contact an outer circumference of a ridge of the case to precisely locate the case. The positioning members (5A, 5B) are driven between the withdrawn position and the locating position by a cam drive including a cam and a cam follower cooperating with each positioning member. The cam follower moves along the inclined surface of the cam provided at the case locating station.
摘要翻译：一种用于定位装有光盘的壳体的装置，包括一对滑动板，可在相反的水平方向上滑动，以便可移动地连接到滑板的端部的一对定位构件（5A，5B）。定位构件在定位构件（5A，5B）的趾面（6a）不与壳体接触的收回静止位置和定位位置之间移动，其中脚趾面接触壳体的脊的外周精确定位的情况。定位构件（5A，5B）通过包括与每个定位构件配合的凸轮和凸轮从动件的凸轮驱动器在缩回位置和定位位置之间被驱动。凸轮从动件沿着设置在壳体定位台处的凸轮的倾斜表面移动。

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