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1. 发明授权

US08709339B2 Apparatus and method for sterilizing vessel with electron beam 有权
标题翻译：用电子束灭菌容器的设备和方法
公开(公告)号：US08709339B2
公开(公告)日：2014-04-29
申请号：US13788205
申请日：2013-03-07
申请人： Toshiya Kobayashi , Mitsuomi Narita , Tomohiko Sugimori , Tsunehiko Yokoi , Yukinobu Nishino , Masami Hayashi , Hideki Nishikawa , Yukihiro Yamamoto , Tokuo Nishi
发明人： Toshiya Kobayashi , Mitsuomi Narita , Tomohiko Sugimori , Tsunehiko Yokoi , Yukinobu Nishino , Masami Hayashi , Hideki Nishikawa , Yukihiro Yamamoto , Tokuo Nishi
IPC分类号： A61L2/00 , G01N23/00 , A01N1/02 , A61K41/00 , A61L9/22
CPC分类号： A01N1/0294 , A61K41/00 , A61L2/00 , A61L2/087 , A61L2/202 , A61L9/22 , A61L2202/10 , A61L2202/23 , B65B55/08 , B67C7/0073
摘要： To prevent electrical charging inside a resin material as well as a surface of a resin vessel at a time of sterilizing the resin vessel by being irradiated with electron beam, a bottle support unit is mounted to a lower end portion of a cylindrical rotating shaft rotatably supported by a rotating wheel. The bottle support unit includes a pair of griper members by which a mouth portion of a bottle is gripped. A ground electrode is disposed to be capable of being inserted into the interior of the resin vessel through a mouth portion thereof, and the interior of the resin vessel is irradiated with the electron beam in a state of the ground electrode being inserted into the resin vessel.
摘要翻译：为了防止在通过照射电子束对树脂容器进行灭菌时树脂材料以及树脂容器的表面进行充电，将瓶支撑单元安装在可旋转地支撑的圆筒形旋转轴的下端部通过旋转轮。瓶支撑单元包括一对夹持构件，通过该一对夹持构件夹持瓶的口部。接地电极被设置成能够通过其口部插入树脂容器的内部，并且在接地电极被插入到树脂容器中的状态下用电子束照射树脂容器的内部。

2. 发明授权

US08415645B2 Apparatus and method for sterilizing vessel with electron beam 有权
标题翻译：用电子束灭菌容器的设备和方法
公开(公告)号：US08415645B2
公开(公告)日：2013-04-09
申请号：US12657491
申请日：2010-01-21
申请人： Toshiya Kobayashi , Mitsuomi Narita , Tomohiko Sugimori , Tsunehiko Yokoi , Yukinobu Nishino , Masami Hayashi , Hideki Nishikawa , Yukihiro Yamamoto , Tokuo Nishi
发明人： Toshiya Kobayashi , Mitsuomi Narita , Tomohiko Sugimori , Tsunehiko Yokoi , Yukinobu Nishino , Masami Hayashi , Hideki Nishikawa , Yukihiro Yamamoto , Tokuo Nishi
IPC分类号： G01N23/00 , A61N5/00 , H01J43/00 , H01J7/24
CPC分类号： A01N1/0294 , A61K41/00 , A61L2/00 , A61L2/087 , A61L2/202 , A61L9/22 , A61L2202/10 , A61L2202/23 , B65B55/08 , B67C7/0073
摘要： It is aimed to prevent electrical charging inside a resin material as well as a surface of a resin vessel at a time of sterilizing the resin vessel by being irradiated with electron beam. A bottle support unit is mounted to a lower end portion of a cylindrical rotating shaft rotatably supported by a rotating wheel. The bottle support unit includes a pair of griper members by which a mouth portion of a bottle is gripped. The bottle rotated and conveyed in a state supported by the bottle support unit is irradiated with the electron beam from an electron beam irradiator to thereby sterilize the bottle. A ground electrode is disposed to be capable of being inserted into the interior of the resin vessel through a mouth portion thereof, and the interior of the resin vessel is irradiated with the electron beam in a state of the ground electrode being inserted into the resin vessel. Since extra electrons or ions generated by the irradiation to the resin vessel with the electron beam flow outside, the charge amount of the resin vessel is alleviated.
摘要翻译：其目的在于通过照射电子束来防止树脂材料以及树脂容器的表面在对树脂容器进行灭菌时的充电。瓶支撑单元安装到由旋转轮可旋转地支撑的圆筒形旋转轴的下端部。瓶支撑单元包括一对夹持构件，通过该一对夹持构件夹持瓶的口部。在由瓶支撑单元支撑的状态下旋转和输送的瓶子被来自电子束照射器的电子束照射，从而对瓶子进行杀菌。接地电极被设置成能够通过其口部插入树脂容器的内部，并且在接地电极被插入到树脂容器中的状态下用电子束照射树脂容器的内部。由于通过向电子束照射到树脂容器而产生的额外的电子或离子流过外部，因此可以减轻树脂容器的电荷量。

3. 发明申请

US20100202918A1 Apparatus and method for sterilizing vessel with electron beam 有权
标题翻译：用电子束灭菌容器的设备和方法
公开(公告)号：US20100202918A1
公开(公告)日：2010-08-12
申请号：US12657491
申请日：2010-01-21
申请人： Toshiya Kobayashi , Mitsuomi Narita , Tomohiko Sugimori , Tsunehiko Yokoi , Yukinobu Nishino , Masami Hayashi , Hideki Nishikawa , Yukihiro Yamamoto , Tokuo Nishi
发明人： Toshiya Kobayashi , Mitsuomi Narita , Tomohiko Sugimori , Tsunehiko Yokoi , Yukinobu Nishino , Masami Hayashi , Hideki Nishikawa , Yukihiro Yamamoto , Tokuo Nishi
IPC分类号： A61L2/08 , A61L2/26 , G21G5/00
CPC分类号： A01N1/0294 , A61K41/00 , A61L2/00 , A61L2/087 , A61L2/202 , A61L9/22 , A61L2202/10 , A61L2202/23 , B65B55/08 , B67C7/0073
摘要： It is aimed to prevent electrical charging inside a resin material as well as a surface of a resin vessel at a time of sterilizing the resin vessel by being irradiated with electron beam. A bottle support unit is mounted to a lower end portion of a cylindrical rotating shaft rotatably supported by a rotating wheel. The bottle support unit includes a pair of griper members by which a mouth portion of a bottle is gripped. The bottle rotated and conveyed in a state supported by the bottle support unit is irradiated with the electron beam from an electron beam irradiator to thereby sterilize the bottle. A ground electrode is disposed to be capable of being inserted into the interior of the resin vessel through a mouth portion thereof, and the interior of the resin vessel is irradiated with the electron beam in a state of the ground electrode being inserted into the resin vessel. Since extra electrons or ions generated by the irradiation to the resin vessel with the electron beam flow outside, the charge amount of the resin vessel is alleviated.
摘要翻译：其目的在于通过照射电子束来防止树脂材料以及树脂容器的表面在对树脂容器进行灭菌时的充电。瓶支撑单元安装到由旋转轮可旋转地支撑的圆筒形旋转轴的下端部。瓶支撑单元包括一对夹持构件，通过该一对夹持构件夹持瓶的口部。在由瓶支撑单元支撑的状态下旋转和输送的瓶子被来自电子束照射器的电子束照射，从而对瓶子进行杀菌。接地电极被设置成能够通过其口部插入树脂容器的内部，并且在接地电极被插入到树脂容器中的状态下用电子束照射树脂容器的内部。由于通过向电子束照射到树脂容器而产生的额外的电子或离子流过外部，因此可以减轻树脂容器的电荷量。

4. 发明申请

US20100326563A1 Method of eliminating static charge from resin vessel, method of sterilizing and filling resin vessel, method of filling and capping resin vessel, apparatus for eliminating static charge from resin vessel, and resin vessel sterilizing and filling system 有权
标题翻译：消除树脂容器静电的方法，树脂容器的灭菌和填充方法，树脂容器的填充和封盖方法，消除树脂容器静电装置，树脂容器灭菌和灌装系统
公开(公告)号：US20100326563A1
公开(公告)日：2010-12-30
申请号：US12803276
申请日：2010-06-23
申请人： Toshiya Kobayashi , Mitsuomi Narita , Tomohiko Sugimori , Tsunehiko Yokoi , Yukinobu Nishino , Masami Hayashi , Takashi Kadoya , Tokuo Nishi , Yukihiro Yamamoto , Takuya Onishi , Takahiro Kida , Kouichi Murata
发明人： Toshiya Kobayashi , Mitsuomi Narita , Tomohiko Sugimori , Tsunehiko Yokoi , Yukinobu Nishino , Masami Hayashi , Takashi Kadoya , Tokuo Nishi , Yukihiro Yamamoto , Takuya Onishi , Takahiro Kida , Kouichi Murata
IPC分类号： B65B3/04
CPC分类号： H05F1/00 , A61L2/087 , B67C7/0073 , H05F3/06
摘要： It is aimed to eliminate charges accumulated inside a wall structure of a resin vessel 2, which is sterilized by an electron beam irradiator 16, and an ionizer 134 disposed outside a filler 112 emits to the outer surface of the resin vessel 2 with negative ions having the same polarity as that of charges accumulated in the wall section of the resin vessel 2, while conveying the resin vessel 2 sterilized by the electron beam irradiator 16 to the filler 112, by which liquid fills the resin vessel 2. A filling nozzle 132 is connected to ground, and an ion flowing path is formed through a liquid column La filling the interior of the resin vessel 2 from the filling nozzle 132. The ions having the negative charges in a filling liquid L flow toward ground side of the ionizer 134, and on the other hand, ions having positive charges are attracted to the inner surface of the resin vessel 2 to thereby neutralize the charges remaining inside the wall structure of the resin vessel 2 with the ions having the positive charges.
摘要翻译：旨在消除由电子束照射器16灭菌的树脂容器2的壁结构中蓄积的电荷，并且设置在填充物112外部的电离器134以负离子发射到树脂容器2的外表面，与树脂容器2的壁部积聚的电荷的极性相同，同时将通过电子束照射器16灭菌的树脂容器2输送到填充剂112，由此填充树脂容器2.填充喷嘴132 连接到地面，并且通过从填充喷嘴132填充树脂容器2的内部的液柱La形成离子流动路径。在填充液L中具有负电荷的离子流向离子发生器134的接地侧，另一方面，具有正电荷的离子被吸引到树脂容器2的内表面，从而以离子h中和残留在树脂容器2的壁结构内的电荷积极收费。

5. 发明授权

US08505269B2 Method, apparatus and system of eliminating static charge and filling and sterilizing resin vessel 有权
标题翻译：消除静电荷和树脂容器灭菌的方法，设备和系统
公开(公告)号：US08505269B2
公开(公告)日：2013-08-13
申请号：US12803276
申请日：2010-06-23
申请人： Toshiya Kobayashi , Mitsuomi Narita , Tomohiko Sugimori , Tsunehiko Yokoi , Yukinobu Nishino , Masami Hayashi , Takashi Kadoya , Tokuo Nishi , Yukihiro Yamamoto , Takuya Onishi , Takahiro Kida , Kouichi Murata
发明人： Toshiya Kobayashi , Mitsuomi Narita , Tomohiko Sugimori , Tsunehiko Yokoi , Yukinobu Nishino , Masami Hayashi , Takashi Kadoya , Tokuo Nishi , Yukihiro Yamamoto , Takuya Onishi , Takahiro Kida , Kouichi Murata
IPC分类号： B65B3/04
CPC分类号： H05F1/00 , A61L2/087 , B67C7/0073 , H05F3/06
摘要： Charges accumulated inside a wall structure of a resin vessel, which is sterilized by an electron beam irradiator, and an ionizer disposed outside a filler emits to the outer surface of the resin vessel are eliminated with negative ions having the same polarity as that of charges accumulated in the wall section of the resin vessel, while conveying the resin vessel sterilized by the electron beam irradiator to the filler, by which liquid fills the resin vessel.
摘要翻译：通过电子束照射器灭菌的树脂容器的壁结构中积聚的电荷和设置在填充物外部的填充物的离子发生器被排出到具有与积累的电荷相同极性的负离子在树脂容器的壁部分中，同时将通过电子束照射器灭菌的树脂容器输送到填充剂，液体填充树脂容器。

6. 发明授权

US08373138B2 Vessel sterilization apparatus 有权
标题翻译：船舶灭菌装置
公开(公告)号：US08373138B2
公开(公告)日：2013-02-12
申请号：US12448308
申请日：2007-12-27
申请人： Yukinobu Nishino , Tokuo Nishi , Yukihiro Yamamoto
发明人： Yukinobu Nishino , Tokuo Nishi , Yukihiro Yamamoto
IPC分类号： H01J37/20
CPC分类号： B65B55/08 , A61L2/087 , B65B31/025 , B65B55/027 , G21K5/10
摘要： An irradiation surface of an electron beam irradiation device 28 is directed toward a vessel 2 conveyed by a vessel conveying device 24 to thereby irradiate the vessel 2 with the electron beam to sterilize the vessel, an irradiation chamber 30 is provided so as to surround the irradiation surface of the electron beam irradiation device 28 and the vessel 2 subjected to the irradiation, a discharge chamber 32 is provided on an outlet side of the irradiation chamber 30, and dry-air supply means 80 for supplying a dried aseptic air is connected to the irradiation chamber 30. By removing moisture within the irradiation chamber 30 which is irradiated with the electron beam, the changing of nitrogen oxide to nitric acid is suppressed to thereby prevent metal portions from corroding.
摘要翻译：电子束照射装置28的照射面朝向由容器输送装置24输送的容器2，从而用电子束照射容器2，对容器进行灭菌，照射室30设置成包围照射电子束照射装置28和经受照射的容器2的表面，在照射室30的出口侧设置有排出室32，并且将用于供给干燥的无菌空气的干燥空气供给装置80连接到照射室30.通过除去照射电子束的照射室30内的水分，可以抑制氮氧化物变为硝酸，从而防止金属部分腐蚀。

7. 发明授权

US08461550B2 Electron beam sterilizer 有权
标题翻译：电子束灭菌器
公开(公告)号：US08461550B2
公开(公告)日：2013-06-11
申请号：US13308619
申请日：2011-12-01
申请人： Yukinobu Nishino , Tokuo Nishi , Yukihiro Yamamoto
发明人： Yukinobu Nishino , Tokuo Nishi , Yukihiro Yamamoto
IPC分类号： G21K5/10 , B65B55/08 , A61L2/08
CPC分类号： A61L2/087 , A61L2202/121 , A61L2202/122 , G21K5/04 , G21K5/10
摘要： Plastic containers fed by an article feeder housed in a shield chamber are sterilized by being irradiated with an electron beam that is radiated from an irradiation window of an electron beam irradiation unit which is coupled to an opening of the shield chamber. In a maintenance mode, an adjustment irradiation box is detachably mounted on the electron beam irradiation unit in covering relation to the irradiation window of the electron beam irradiation unit. The adjustment irradiation box houses therein an electron beam receiver for receiving the electron beam radiated from the irradiation window, a cooling mechanism for cooling the electron beam receiver, and an exhaust mechanism for discharging an atmosphere in the adjustment irradiation box.
摘要翻译：由容纳在屏蔽室中的物品馈送器馈送的塑料容器通过照射从与屏蔽室的开口耦合的电子束照射单元的照射窗辐射的电子束来灭菌。在维护模式中，调整照射盒以与电子束照射单元的照射窗相关的方式可拆卸地安装在电子束照射单元上。调节照射箱内装有用于接受从照射窗辐射的电子束的电子束接收器，用于冷却电子束接收器的冷却机构，以及用于排出调节照射盒中的气氛的排气机构。

8. 发明申请

US20100252752A1 VESSEL STERILIZATION APPARATUS 审中-公开
标题翻译：血管消毒装置
公开(公告)号：US20100252752A1
公开(公告)日：2010-10-07
申请号：US12734710
申请日：2008-11-10
申请人： Yukinobu Nishino , Tokuo Nishi , Yukihiro Yamamoto
发明人： Yukinobu Nishino , Tokuo Nishi , Yukihiro Yamamoto
IPC分类号： A61L2/08
CPC分类号： B65G47/847 , A61L2/087 , A61L2202/122 , A61L2202/23 , B65B55/08 , B65G47/244
摘要： In an irradiation region A in which an electron beam irradiator emits an electron beam through an irradiating surface 12a of the electron beam irradiator, areas B and D are formed in which one surface of a rectangular resin bottle 8 is in parallel with the irradiating surface 12a. Grippers 6 are arranged to an outer peripheral portion of a rotary body 14 in a circumferential direction thereof at an equal interval, and the resin bottles 8 are conveyed with neck portions 8a thereof being held. Rotating means (52, 58, 62) that rotate the grippers 6 with respect to the rotary body 14 and forward/rearward moving means (18, 50) that keeps constant a distance from the irradiating surface 12a of the electron beam irradiator are provided. In the electron beam irradiation region A, by rotating the gripper 6 by the rotating means, the resin bottle 8 is moved while maintaining one surface of the rectangular resin bottle 8 to be in parallel with the flat irradiating surface 12a.
摘要翻译：在电子束照射器通过电子束照射器的照射面12a发射电子束的照射区域A中，形成区域B，D，其中矩形树脂瓶8的一个表面与照射表面12a平行。夹爪6以等间隔配置在旋转体14的圆周方向的外周部，树脂瓶8被保持颈部8a输送。提供使夹持器6相对于旋转体14旋转的旋转装置（52,58,62）以及与电子束照射器的照射面12a保持恒定距离的前后移动装置（18,50）。在电子束照射区域A中，通过旋转装置旋转夹持器6，使树脂瓶8移动，同时保持矩形树脂瓶8的一个表面与平坦照射表面12a平行。

9. 发明申请

US20100140507A1 ELECTRON BEAM STERILIZER 有权
标题翻译：电子束灭菌器
公开(公告)号：US20100140507A1
公开(公告)日：2010-06-10
申请号：US12450338
申请日：2008-03-05
申请人： Yukinobu Nishino , Tokuo Nishi , Yukihiro Yamamoto
发明人： Yukinobu Nishino , Tokuo Nishi , Yukihiro Yamamoto
IPC分类号： B65B55/08 , G21K5/10 , G21K5/08
CPC分类号： B65B55/08 , G21K5/02 , G21K5/04 , G21K5/08 , G21K5/10
摘要： Even in a case where a spark is generated in an electron beam irradiation device 28, all the vessels 2 now being conveyed are surely sterilized by the irradiation with the electron beam. The electron beam is emitted by heating filaments 42 arranged in a vacuum chamber 40, and the vessels 2 are irradiated with the electron beam taken out into atmosphere through a window foil 48 of an irradiation window 46 formed to an irradiation section 44. The vessels 2 are conveyed in a state of being held by vessel holding portions 36A and 36B of a vessel conveying device 24 and pass in front of the irradiation window 46. Although the electron beam irradiation is temporarily interrupted when a spark is generated, a length of the irradiation window 46 in a vessel conveying direction X is made larger than a vessel conveying distance in an interruption time.
摘要翻译：即使在电子束照射装置28中产生火花的情况下，现在被输送的所有容器2通过电子束的照射确实被灭菌。通过加热布置在真空室40中的细丝42发射电子束，并且通过形成于照射部分44的照射窗46的窗口薄片48将电子束照射到大气中。容器2 在由容器输送装置24的容器保持部36A，36B保持的状态下输送，并且在照射窗46的前方通过。虽然在发生火花时电子束照射暂时中断，但照射长度在容器输送方向X上的窗口46比在中断时间的容器输送距离大。

10. 发明授权

US08618503B2 Electron beam sterilizer 有权
标题翻译：电子束灭菌器
公开(公告)号：US08618503B2
公开(公告)日：2013-12-31
申请号：US12451535
申请日：2008-05-20
申请人： Yukinobu Nishino , Tokuo Nishi , Yukihiro Yamamoto
发明人： Yukinobu Nishino , Tokuo Nishi , Yukihiro Yamamoto
IPC分类号： A61L2/08 , G21K5/02
CPC分类号： A61L2/087 , A61L2202/23 , B65B55/08 , G21K5/02 , G21K5/10
摘要： An electron beam sterilizer has a bottle holder 28 provided with a rotation shaft 38, a neck gripper 70 mounted to a lower end of the rotation shaft 38, a rotating body 30 for rotating and moving the neck gripper 70 and a rotator revolver (segment gear 54, pinion gear 46, disc-shaped cam 66, etc.), and while conveying the resin bottle 2 in the state of being held, the resin bottle 2 is sterilized by irradiation with the electron beam through the irradiation window 19 of the electron beam irradiation device 18. The entire surface of the resin bottle 2 is completely sterilized by being rotated by the rotator during the movement in front of the irradiation window 19 and, thereafter, the rotator is inverted in position to return the neck gripper to thereby discharge the bottle.
摘要翻译：电子束灭菌器具有设置有旋转轴38的瓶保持器28，安装在旋转轴38的下端的颈部夹持器70，用于使颈部夹持器70旋转和移动的旋转体30和旋转轮（分段齿轮 54，小齿轮46，圆盘状凸轮66等），并且在保持树脂瓶2的状态下输送树脂瓶2时，通过电子束的照射通过电子的照射窗19对树脂瓶2进行灭菌光束照射装置18.树脂瓶2的整个表面通过旋转器在照射窗口19的前方移动期间被旋转而完全消毒，此后，旋转体在其位置反转以使颈部夹持器返回从而排出瓶子。

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