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1. 发明授权

US4654132A Separation and purification of biomembrane proteins 失效
标题翻译：生物膜蛋白的分离和纯化
公开(公告)号：US4654132A
公开(公告)日：1987-03-31
申请号：US758247
申请日：1985-07-24
申请人： Toshio Takagi , Masahiro Fukuda , Kazuo Ohbu
发明人： Toshio Takagi , Masahiro Fukuda , Kazuo Ohbu
IPC分类号： C12P21/00 , A61K35/00 , A61K35/23 , A61K38/46 , B01D57/02 , C07K1/26 , C12N9/14 , C12P21/02 , G01N27/447 , C07K3/14
CPC分类号： C07K1/26 , C12N9/14 , C12P21/02 , G01N27/44747
摘要： A method for separating and purifying a biomembrane protein from biomembrane by subjecting the biomembrane to gel electrophoresis in the presence of at least one anionic surfactant having the general formula (I):RO--XO).sub.m (YO).sub.n SO.sub.3 M (I)wherein R represents an alkyl group having 6 to 22 carbon atoms or an alkylphenyl group having 6 to 22 carbon atoms, X and Y independently represent a hydrocarbon residue having 1 to 4 carbon atoms, m and n independently represent a number of from zero to 40 provided that m+n is 4 to 40, and M represents an alkali metal, an alkaline earth metal, an amine, or ammonium.Thus, the desired biomembrane protein can be separated and purified with a high purity without denaturing the protein and also without impairing the biological function thereof.
摘要翻译：一种通过在至少一种具有通式（I）的阴离子表面活性剂：RO-XO）m（YO）n SO 3 M（I）的存在下使生物膜进行凝胶电泳从生物膜中分离和纯化生物膜蛋白的方法，其中R表示具有6至22个碳原子的烷基或具有6至22个碳原子的烷基苯基，X和Y独立地表示具有1至4个碳原子的烃基，m和n独立地表示0至40的数，条件是m + n为4〜40，M为碱金属，碱土金属，胺或铵。因此，可以高纯度地分离和纯化所需的生物膜蛋白质，而不使蛋白质变性，并且也不损害其生物学功能。

2. 发明授权

US4287102A Detergent composition 失效
标题翻译：洗涤剂组成
公开(公告)号：US4287102A
公开(公告)日：1981-09-01
申请号：US131636
申请日：1980-03-19
申请人： Nobuyuki Miyajima , Nobuo Johna , Naoki Mizushima , Kazuo Ohbu
发明人： Nobuyuki Miyajima , Nobuo Johna , Naoki Mizushima , Kazuo Ohbu
IPC分类号： A23L1/00 , A61K8/40 , A61K8/46 , A61Q5/02 , C11D1/14 , C11D1/75 , C11D1/83
CPC分类号： C11D1/83 , A23L5/57 , A61K8/40 , A61K8/466 , A61Q5/02 , C11D1/75 , A61K2800/596
摘要： A detergent composition, suitable for use in washing vegetables and dishes and shampooing human hair, having both good detergency and little hand roughening action is presented. This detergent composition contains:(a) a water-soluble salt of olefin sulfonic acid having 12 to 16 carbon atoms and(b) a tertiary amine oxide having the formula ##STR1## wherein R.sup.1 is an alkyl group of 10 to 14 carbon atoms, and R.sup.2 and R.sup.3 are independently an alkyl or hydroxyalkyl group, of 1 to 3 carbon atoms. The contents of each of said components (a) and (b) in the composition being within the range of from 2 to 20% by weight, and the mol ratio of the component (a) to the component (b) being within the range of from 1.5/1 to 0.5/1, and the pH of an aqueous solution of the detergent composition being within the range of from 7.3 to 8.0 at the concentration when it is used in washing vegetables and dishes.
摘要翻译：本发明提供一种洗涤剂组合物，其适用于洗涤蔬菜和菜肴以及洗发人的头发，具有良好的去污力和少量的粗糙化作用。该洗涤剂组合物包含：（a）具有12至16个碳原子的烯烃磺酸的水溶性盐和（b）具有式“IMAGE”的叔胺氧化物，其中R 1是10至14个碳原子的烷基，且R 2和R 3独立地为具有1至3个碳原子的烷基或羟烷基。组合物中所述组分（a）和（b）中的每一种的含量在2至20重量％的范围内，组分（a）与组分（b）的摩尔比在范围内为1.5 / 1〜0.5 / 1，洗涤剂组合物的水溶液的pH在7.3〜8.0的范围内，其浓度用于洗涤蔬菜和菜肴时。

3. 发明授权

US4259216A Process for producing liquid detergent composition 失效
标题翻译：生产液体洗涤剂组合物的方法
公开(公告)号：US4259216A
公开(公告)日：1981-03-31
申请号：US131637
申请日：1980-03-19
申请人： Nobuyuki Miyajima , Nobuo Johna , Naoki Mizushima , Kazuo Ohbu
发明人： Nobuyuki Miyajima , Nobuo Johna , Naoki Mizushima , Kazuo Ohbu
IPC分类号： C11D11/00 , C11D1/14 , C11D1/29 , C11D1/75 , C11D1/83 , C11D17/00
CPC分类号： C11D1/83 , C11D3/3418 , C11D1/143 , C11D1/29 , C11D1/75
摘要： A production process of a liquid detergent composition having both good detergency and little hand roughening action is presented. This liquid detergent composition can be produced by mixing an anionic surface active agent and a semi-polar nonionic surface active agent, each in the stage of an aqueous solution, and then, adding a specified arylsulfonic acid to this mixture in such a manner that the produced liquid detergent composition contains 6 to 25% by weight of the anionic surface active agent, 2 to 8% by weight of the semi-polar nonionic surface active agent and 0.2 to 3.0% by weight of the arylsulfonic acid.
摘要翻译：本发明提供了具有良好去污力和少量手工粗糙作用的液体洗涤剂组合物的生产方法。这种液体洗涤剂组合物可以通过在水溶液的阶段中混合阴离子表面活性剂和半极性非离子表面活性剂，然后向该混合物中加入特定的芳基磺酸来制备，制备的液体洗涤剂组合物含有6至25重量％的阴离子表面活性剂，2至8重量％的半极性非离子表面活性剂和0.2至3.0重量％的芳基磺酸。

4. 发明授权

US4029591A Liquid detersive bleaching composition 失效
标题翻译：液体洗涤漂白组合物
公开(公告)号：US4029591A
公开(公告)日：1977-06-14
申请号：US615393
申请日：1975-09-22
申请人： Kazuo Ohbu , Yuichi Takada , Shigemi Nakamura
发明人： Kazuo Ohbu , Yuichi Takada , Shigemi Nakamura
IPC分类号： C11D1/29 , C11D3/395 , C11D7/54
CPC分类号： C11D1/29 , C11D3/3956
摘要： A liquid detersive bleaching composition which comprises 3 to 10 wt.% of sodium hypochlorite (in terms of the amount of available chlorine), 0.5 to 3 wt.% of caustic alkali, 0.3 to 7 wt.% of polyoxyethylene alkylphenyl ether sulfate (a) having the formula (I) and 0.1 to 5 wt.% of polyoxyethylene alkylphenyl ether sulfate sulfonate (b) having the formula (II), wherein the molar ratio of (a) to (b) is in the range of from 20/80 to 85/15 and the total amount of (a) and (b) is in the range of from more than 0.5 wt.% to less than 10 wt.%.Formula (I): ##STR1## (wherein R represents straight-chain or branched-chain alkyl group having 5 to 15 carbon atoms, m is an integer ranging from 3 to 15, and M represents Na or K.)formula (II): ##STR2## (wherein R' represents straight-chain or branched-chain alkyl group having 5 to 15 carbon atoms, n is an integer ranging from 3 to 15, and M represents Na or K.)
摘要翻译：一种液体洗涤漂白组合物，其包含3至10重量％的次氯酸钠（以可用氯的量计），0.5-3重量％的苛性碱，0.3至7重量％的聚氧乙烯烷基苯基醚硫酸盐（a ）和0.1〜5重量％的具有式（II）的聚氧乙烯烷基苯基醚硫酸酯磺酸酯（b），其中（a）与（b）的摩尔比在20 / 80〜85/15，（a）和（b）的总量在大于0.5重量％至小于10重量％的范围内。

5. 发明授权

US4486334A Method for the preparation of an aqueous dispersion of pearlescent agent 失效
标题翻译：珠光剂水分散体的制备方法
公开(公告)号：US4486334A
公开(公告)日：1984-12-04
申请号：US362535
申请日：1982-03-26
申请人： Teruo Horiuchi , Nobuo Jona , Kazuo Ohbu , Naoki Mizushima
发明人： Teruo Horiuchi , Nobuo Jona , Kazuo Ohbu , Naoki Mizushima
IPC分类号： C11D3/40 , A61K8/00 , A61K8/02 , A61K8/37 , A61K8/41 , A61K8/46 , A61Q5/02 , A61Q19/10 , B01F3/08 , B01F17/00 , C09D17/00 , C09K19/00 , C11D3/20 , C11D9/26 , C11D17/00 , B01J13/00 , C09K3/34
CPC分类号： C11D3/0089 , A61K8/0295 , A61K8/375 , A61K8/416 , A61K8/463 , A61Q19/10 , A61Q5/02 , C09D17/003 , C09K19/00 , C11D17/0013 , C11D17/0026 , C11D3/2093 , Y10S516/04 , Y10S516/06
摘要： The invention provides a novel and improved method for the preparation of a highly concentrated aqueous dispersion of a pearlescent agent, which is typically an ethyleneglycol di(fatty acid) ester, capable of forming very thin leaf crystals exhibiting pearlescence to be used for imparting pleasant appearance to detergents, toiletries, such as hair shampoos, hair rinses and others, and the like admixed therewith. The method is performed by solubilizing the pearlescent agent in an aqueous solution of a surfactant, at least a substantial amount thereof being in the state of middle phase liquid crystals, at or above the melting point of the pearlescent agent and succeedingly cooling the above obtained mixture to room temperature whereby to crystallize the pearlescent agent in situ while the state of the middle phase liquid crystals of the surfactant is kept substantially unchanged.
摘要翻译：本发明提供了一种制备珠光剂的高浓度水分散体的新型改进方法，该珠光剂水性分散体通常是乙二醇二（脂肪酸）酯，能够形成呈现珠光的非常薄的叶状晶体，以用于赋予令人愉悦的外观洗发剂，洗发剂，如洗发剂，头发漂洗剂等混合。该方法通过将珠光剂溶解在表面活性剂的水溶液中，其至少大部分处于中间相液晶的状态，等于或高于珠光剂的熔点，然后将上述所得混合物达到室温，从而使表面活性剂的中间相液晶的状态基本保持不变，从而原位结晶珠光剂。

6. 发明授权

US3969375A Method of manufacturing salt of .alpha.-sulfofatty acid ester 失效
标题翻译：制备{60-磺基酸酯的盐的方法
公开(公告)号：US3969375A
公开(公告)日：1976-07-13
申请号：US524709
申请日：1974-11-18
申请人： Osamu Okumura , Takenobu Sakatani , Kazuo Ohbu , Masuzo Nagayama
发明人： Osamu Okumura , Takenobu Sakatani , Kazuo Ohbu , Masuzo Nagayama
IPC分类号： C07C67/00 , C07C301/00 , C07C303/06 , C07C303/32 , C07C309/17 , C11D1/28 , C07C143/12
CPC分类号： C07C303/06
摘要： A neutralized product containing salt of .alpha.-sulfofatty acid ester in high concentration can be produced by the method comprising the steps of (1) sulfonating fatty acid ester by contacting a gaseous mixture of sulfur trioxide (SO.sub.3) and an inert gas containing 1 - 15% by volume of SO.sub.3 with a film of a fatty acid ester, said ester having the formula RCH.sub.2 COOR' (wherein R is alkyl having 8 - 18 carbon atoms and R' is alkyl having 1 - 5 carbon atoms), under the conditions that the molar ratio of SO.sub.3 to said fatty acid ester is in the range of 1.0 - 1.5, the temperature is in the range of 50.degree. - 85.degree.C and the time of contact is in the range of 0.5 - 30 seconds; (2) contacting a film of the reaction product obtained by step (1) into contact with said gaseous mixture, under the conditions of a temperature in the range of 95 - 150.degree.C and a time of contact in the range of 3 - 120 seconds; and (3) instantly neutralizing the reaction product obtained by step (2) with a base selected from the group consisting of an aqueous solution of alkali metal hydroxide, ammonia water and ethanol amine while retaining the condition that the pH value is in the range of 6 - 10 and the temperature is less than 70.degree.C. This neutralized product is usable as the active ingredient a detergent without subjecting it to any further treatment.
摘要翻译：含有高浓度的α-磺基脂肪酸酯的中和产物可以通过以下方法制备：（1）通过使三氧化硫（SO 3）和含有1-15的惰性气体的气体混合物脂肪酸酯膜的SO 3体积％，所述具有式RCH 2 COOR'的酯（其中R是具有8-18个碳原子的烷基，R'是具有1-5个碳原子的烷基），在 SO 3与所述脂肪酸酯的摩尔比在1.0-1.5的范围内，温度在50-85℃的范围内，接触时间在0.5-30秒的范围内; （2）使步骤（1）获得的反应产物的膜与所述气体混合物接触，在95-150℃的温度和3〜120℃范围内的接触时间秒; 和（3）用碱金属氢氧化物水溶液，氨水和乙醇胺立即中和由步骤（2）获得的反应产物与碱金属氢氧化物，氨水和乙醇胺的水溶液，同时保持pH值在 6-10，温度低于70℃。该中和产物可用作活性成分，不用进行任何进一步的处理。

7. 发明授权

US4235759A Liquid detergent compositions 失效
标题翻译：液体洗涤剂组合物
公开(公告)号：US4235759A
公开(公告)日：1980-11-25
申请号：US45134
申请日：1979-06-04
申请人： Kazuo Ohbu , Nobuo Johna , Ichiro Kashiwa
发明人： Kazuo Ohbu , Nobuo Johna , Ichiro Kashiwa
IPC分类号： C11D1/29 , C11D1/62 , C11D1/65 , C11D17/00
CPC分类号： C11D1/65 , C11D1/29 , C11D1/62
摘要： A liquid detergent composition which comprises an anionic surface active agent of polyoxyalkylene alkyl ether sulfate type and a cationic surface active agent of mono-long chain alkyl quaternary ammonium salt type at a mol ratio of the former to the latter in the range of from 8:1 to 1:1 is not only mild to the human skin but also capable of demonstrating superb detergency.
摘要翻译：一种液体洗涤剂组合物，其包含聚氧化烯烷基醚硫酸盐型的阴离子表面活性剂和单长烷基季铵盐型的阳离子表面活性剂，前者与后者的摩尔比为8： 1至1：1不仅对人体皮肤轻微，而且能够显示出极好的去污力。

8. 发明授权

US3951877A Heavy-duty granular detergent composition with sodium citrate builder 失效
标题翻译：具有柠檬酸钠助洗剂的重型颗粒洗涤剂组合物
公开(公告)号：US3951877A
公开(公告)日：1976-04-20
申请号：US378922
申请日：1973-07-13
申请人： Osamu Okumura , Kazuo Ohbu , Mitsuharu Kachi , Masuzo Nagayama
发明人： Osamu Okumura , Kazuo Ohbu , Mitsuharu Kachi , Masuzo Nagayama
IPC分类号： B01J2/28 , C11D1/02 , C11D3/02 , C11D3/20 , C11D3/08 , C11D1/14 , C11D1/22 , C11D3/04
CPC分类号： C11D17/06 , C11D1/02 , C11D3/046 , C11D3/2086
摘要： A heavy-duty granular detergent composition consisting of 10 to 60 wt. percent of sodium citrate, 5 to 40 wt. percent of non-soap anionic surfactants, 0.1 to 10 wt. percent of inorganic aluminum salts and additives for use in conventional detergents, the weight ratio of the citrate to the surfactants being 1/5 to 10/1.
摘要翻译：一种重垢颗粒洗涤剂组合物，其由10至60wt。柠檬酸钠的百分比为5〜40wt。百分比的非皂阴离子表面活性剂，0.1-10重量％百分比的用于常规洗涤剂的无机铝盐和添加剂，柠檬酸盐与表面活性剂的重量比为1/5至10/1。

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