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1. 发明授权

US3962446A Analgesic compositions containing 2-cyanoalkylbenzomorphan derivatives and salts thereof 失效
标题翻译：含有2-氰基烷基苯并喃衍生物及其盐的止痛组合物
公开(公告)号：US3962446A
公开(公告)日：1976-06-08
申请号：US523412
申请日：1974-11-13
申请人： Toshio Atsumi , Kenji Kobayashi , Yoshiaki Takebayashi , Hisao Yamamoto
发明人： Toshio Atsumi , Kenji Kobayashi , Yoshiaki Takebayashi , Hisao Yamamoto
IPC分类号： A61K31/395 , A61K31/485
CPC分类号： A61K31/395
摘要： An analgesic composition comprising an analgesically effective amount of at least one 6,7-benzomorphan derivative of the formula: ##SPC1##Wherein R is a hydrogen atom, a hydroxyl group, a C.sup.1 - C.sup.3 alkoxy group or a C.sup.1 - C.sup.8 alkanoyloxy group; R.sub.1 is a hydrogen atom, a C.sup.1 - C.sup.5 alkyl group, a phenyl group, a halophenyl group, an alkylphenyl group wherein the alkyl moiety has 1 to 3 carbon atoms, an alkoxyphenyl group wherein the alkoxy moiety has 1 to 3 carbon atoms, a trifluoromethylphenyl group, an alkylthiophenyl group wherein the alkylthio moiety has 1 to 3 carbon atoms or a group of the formula (C.sub.m H.sub.2m.sub.-p.sub.+1) - (R.sub.9).sub.p wherein m is an integer of 1 - 6, p is an integer of 1 - 2 and R.sub.9 is a C.sup.1 - C.sup.3 alkoxy group; R.sub. 2 is a hydrogen atom or a C.sup.1 - C.sup.3 alkyl group; R.sub.3 is a hydrogen atom, a C.sup.1 - C.sup.3 alkyl group, a phenyl group or an alkoxyphenyl group wherein the alkoxy moiety has 1 to 3 carbon atoms; R.sub.4 is a hydrogen atom or a hydroxyl group, or R.sub.3 and R.sub.4 may form a C.sup.1 - C.sup.3 alkylidene group or a carbonyl group together with a carbon atom to which these substituents are bonded; R.sub.5 is a hydrogen atom or C.sup.1 - C.sup.3 alkyl group; R.sub.6 is a hydrogen atom or a methyl group; R.sub.7 and R.sub.8 are independently a hydrogen atom or a C.sup.1 - C.sup.2 alkyl group; and n is an integer of 0 - 2; or an acid addition salt thereof, and a pharmaceutically acceptable carrier or diluent, is disclosed.
摘要翻译：一种止痛组合物，其包含镇痛有效量的至少一种下式的6,7-苯并吗啉衍生物：WHEREIN R是氢原子，羟基，C1-C3烷氧基或C1-C8烷酰氧基; R1为氢原子，C1-C5烷基，苯基，卤代苯基，烷基部分为碳原子数1〜3的烷基苯基，烷氧基部分为碳原子数1〜3的烷氧基苯基，三氟甲基苯基，其中烷硫基部分具有1至3个碳原子的烷硫基苯基或式（CmH2m-p + 1） - （R9）p的基团，其中m是1-6的整数，p是整数1 - 2和R9是C1-C3烷氧基; R 2是氢原子或C 1 -C 3烷基; R3是氢原子，C1-C3烷基，苯基或烷氧基苯基，其中烷氧基部分具有1至3个碳原子; R4是氢原子或羟基，或者R3和R4可以与这些取代基结合的碳原子一起形成C1-C3亚烷基或羰基; R5是氢原子或C1-C3烷基; R6是氢原子或甲基; R 7和R 8独立地为氢原子或C 1 -C 2烷基; n为0-2的整数; 或其酸加成盐，以及药学上可接受的载体或稀释剂。

2. 发明授权

US3950346A Novel process for producing 2-ketoethylbenzomorphan derivatives and salts thereof 失效
标题翻译：生产2-乙基苯并吡喃衍生物的新方法及其制备方法
公开(公告)号：US3950346A
公开(公告)日：1976-04-13
申请号：US356807
申请日：1973-05-03
申请人： Toshio Atsumi , Kenji Kobayashi , Yoshiaki Takebayashi , Hisao Yamamoto
发明人： Toshio Atsumi , Kenji Kobayashi , Yoshiaki Takebayashi , Hisao Yamamoto
IPC分类号： C07D221/26
CPC分类号： C07D221/26
摘要： 2-Ketoethyl-6,7-benzomorphan derivatives of the formula: ##SPC1##And their pharmaceutically acceptable non-toxic salts, which are useful as non-addictive analgesics and pain-relieving agents and can be prepared by reacting the corresponding 6,7-benzomorphan derivative of the formula: ##SPC2##With a vinyl carbonyl compound of the formula: ##EQU1## [wherein R' is a hydrogen atom or a group of the formula: --OR" (wherein R" is a hydrogen atom, an alkanoyl group, an alkyl group, an aralkyl group, an alkoxycarbonylmethyl group or a tetrahydropyranyl group), R.sub.1 is a hydrogen atom, an alkyl group or a substituted or unsubstituted aryl group, R.sub.2 is a hydrogen atom or an alkyl group and A is an alkyl group, an alkoxy group, a substituted or unsubstituted aryl group or a substituted or unsubstituted amino group].

3. 发明授权

US3953441A Preparation of 2-benzoylalkylbenzomorphan 失效
标题翻译： 2-苯甲酰基烷基苯并咪唑的制备
公开(公告)号：US3953441A
公开(公告)日：1976-04-27
申请号：US150841
申请日：1971-06-07
申请人： Toshio Atsumi , Kenji Kobayashi , Yoshiaki Takebayashi , Hisao Yamamoto
发明人： Toshio Atsumi , Kenji Kobayashi , Yoshiaki Takebayashi , Hisao Yamamoto
IPC分类号： C07D211/70 , C07D221/26
CPC分类号： C07D221/26 , C07D211/70
摘要： A novel process for preparing 2-benzoylalkylbenzomorphan derivatives and salts thereof, represented by the formula ##SPC1##Wherein n, R, R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are as defined in the specification. The process comprises reacting a pyridinium derivative of the formula, ##SPC2##Wherein X is a halogen atom and Y' is an ethylenedioxy group; with a Grignard reagent of the formula, ##SPC3##Wherein R' is a hydrogen atom or a C.sub.1 -C.sub.3 alkoxy group and Z is a halogen atom, to yield a 1,2-dihydropyridine derivative of the formula; ##SPC4##And then reducing the said 1,2-dihydropyridine derivative to give a 1,2,5,6-tetrahydropyridine derivative of the formula, ##SPC5##Wherein Y is an oxygen atom or an ethylenedioxy group, and further cyclizing the obtained 1,2,5,6-tetrahydropyridine derivative.
摘要翻译：由式WHEREIN N，R，R1，R2，R3和R4表示的用于制备2-苯甲酰基烷基苯并喃衍生物及其盐的新方法如本说明书中所定义。该方法包括使下式的吡啶鎓衍生物WHEREIN X是卤素原子，Y'是亚乙二氧基; 与下式的格利雅试剂，其中R'是氢原子或C1-C3烷氧基，Z是卤素原子，得到下式的1,2-二氢吡啶衍生物; 然后减少所得的1,2-二氢吡啶衍生物，得到本发明的1,2,5,6-四氢吡啶衍生物，其中Y是氧原子或亚乙二氧基，进一步环化得到的1,2,5,6-四氢吡啶衍生物， 6-四氢吡啶衍生物。

4. 发明授权

US3951984A 3-Benzazocine compounds 失效
标题翻译： 3-苯并吖嗪化合物
公开(公告)号：US3951984A
公开(公告)日：1976-04-20
申请号：US425717
申请日：1973-12-18
申请人： Michio Kimura , Takeshi Nakajima , Toshio Atsumi , Kenji Kobayashi , Yoshiaki Takebayashi , Shigeho Inaba , Hisao Yamamoto
发明人： Michio Kimura , Takeshi Nakajima , Toshio Atsumi , Kenji Kobayashi , Yoshiaki Takebayashi , Shigeho Inaba , Hisao Yamamoto
IPC分类号： C07D471/08 , C07D221/26
CPC分类号： C07D471/08
摘要： A 3-benzazocine compound of the formula: ##SPC1##Wherein R.sub.1, R.sub.3, R.sub.4, R.sub.5 and R.sub.8 are each hydrogen or lower alkyl, R.sub.2 is hydrogen, lower alkyl or phenyl and R.sub.6 and R.sub.7 are each lower alkyl, and its pharmaceutically acceptable acid addition salts, which are useful as analgesics and can be produced by reacting a tetrahydropyridine compound of the formula: ##SPC2##Wherein R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are each as defined above or its salt with a Lewis acid.
摘要翻译：下式的3-苯并吖嗪化合物：

5. 发明授权

US3966939A Novel 2-substituted 6,7-benzomorphan derivatives and salts thereof in analgesic compositions 失效
标题翻译：新颖的2-取代的6,7-苯并恶嗪衍生物及其盐在止痛组合物中
公开(公告)号：US3966939A
公开(公告)日：1976-06-29
申请号：US558655
申请日：1975-03-17
申请人： Kenji Kobayashi , Toshitsugu Fukumaru , Hiroyuki Mizote , Shigeho Inaba , Hisao Yamamoto
发明人： Kenji Kobayashi , Toshitsugu Fukumaru , Hiroyuki Mizote , Shigeho Inaba , Hisao Yamamoto
IPC分类号： A61K31/395 , A61K31/485
CPC分类号： A61K31/395
摘要： Novel 2-substituted 6,7-benzomorphan derivatives of the formula: ##SPC1##And acid addition salts thereof, which are useful as non-addicting analgesics, pain relieving agents and antitussives and can be prepared by reacting 6,7-benzomorphan derivatives of the formula: ##SPC2##With the reactive derivatives of alcohols of the formula: ##EQU1## [wherein R is a hydrogen atom, a hydroxyl group, an alkoxy group or an alkanoyloxy group; R.sub.1 is a hydrogen atom, an alkyl group, an alkoxyalkyl group or a substituted or unsubstituted aryl group; R.sub.3 is a hydrogen atom or a hydroxyl group; R.sub.4 is a hydrogen atom, an alkyl group or a substituted or unsubstituted aryl group, or R.sub.3 and R.sub.4 may form an alkylidene group or a carbonyl group together with the carbon atom to which these substituents are bonded; R.sub.2, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9 and R.sub.10 are each a hydrogen atom or an alkyl group; A is an alkylene group; and m is an integer of 0 to 2].
摘要翻译：具有下式的新颖的2-取代的6,7-苯并吗啉衍生物：

6. 发明授权

US3961066A 6,7-Benzomorphan derivatives 失效
标题翻译： 6,7-苯并吗啉衍生物
公开(公告)号：US3961066A
公开(公告)日：1976-06-01
申请号：US456268
申请日：1974-03-29
申请人： Toshitsugu Fukumaru , Kenji Kobayashi , Hiroyuki Mizote , Shigeho Inaba , Hisao Yamamoto
发明人： Toshitsugu Fukumaru , Kenji Kobayashi , Hiroyuki Mizote , Shigeho Inaba , Hisao Yamamoto
IPC分类号： A61K31/47 , A61P25/04 , C07D211/70 , C07D211/82 , C07D221/26
CPC分类号： C07D211/70 , C07D221/26 , Y02P20/55 , Y10S514/849
摘要： A novel 2-substituted-6,7-benzomorphan derivative of the formula: ##SPC1##And its acid addition salts, which are useful as non-addicting analgesics and antitussives and can be prepared by reacting a 2-unsubstituted-6,7-benzomorphan derivative of the formula: ##SPC2##With the reactive derivative of an alcohol of the formula:HOA',optionally followed by elimination of the protective group in the resulting product, wherein R.sub.1 is hydrogen, lower alkyl or acyl; R.sub.2 and R.sub.3 are each lower alkyl; A is lower alkyl, cyano(lower)alkyl, benzoyl(lower)alkyl, ar(lower)alkyl, lower alkenyl or cyclo(lower)alkyl(lower)alkyl; and A' is a group as mentioned in A or benzoyl(lower)alkyl of which the carbonyl group is masked with a suitable protective group.
摘要翻译：一种下式的新型2-取代-6,7-苯并吗啉衍生物：

7. 发明授权

US09450439B2 Secondary battery system and operating method of secondary battery 有权
标题翻译：二次电池系统和二次电池的操作方法
公开(公告)号：US09450439B2
公开(公告)日：2016-09-20
申请号：US14237909
申请日：2012-06-13
申请人： Hiroo Hongo , Koji Kudo , Kenichi Ishii , Kenji Kobayashi , Takayuki Nyu
发明人： Hiroo Hongo , Koji Kudo , Kenichi Ishii , Kenji Kobayashi , Takayuki Nyu
IPC分类号： H02J7/00 , H01M10/44 , H01M4/505 , H01M10/052 , H01M10/42
CPC分类号： H02J7/0068 , H01M4/505 , H01M10/052 , H01M10/44 , H01M2010/4271 , Y02E60/122 , Y02P70/54 , Y02T10/7011
摘要： A secondary battery has a progressively deteriorating SOC in which battery performance deteriorates when the secondary battery is stored, and is charged and discharged by a control device. An information processing device stores a preset first threshold smaller than the progressively deteriorating SOC of the secondary battery and a preset second threshold greater than the progressively deteriorating SOC, and separates the range from the minimum SOC to the maximum SOC of the secondary battery into, at least, two regions by setting the section from the first threshold to the second threshold as a boundary to thereby cause the control device to charge or discharge the secondary battery within any of the above regions.
摘要翻译：二次电池在存储二次电池时电池性能恶化的SOC逐渐恶化，并且通过控制装置进行充放电。信息处理装置存储比二次电池的逐渐劣化的SOC小的预设的第一阈值和大于逐渐恶化的SOC的预设的第二阈值，并且将从最小SOC到最小SOC的范围分离成至少两个区域通过将从第一阈值到第二阈值的部分设置为边界，从而使得控制装置在任何上述区域内对二次电池进行充电或放电。

8. 发明授权

US09047219B2 Storage system, storage control device, and storage control method 有权
标题翻译：存储系统，存储控制装置和存储控制方法
公开(公告)号：US09047219B2
公开(公告)日：2015-06-02
申请号：US13570398
申请日：2012-08-09
申请人： Hidejirou Daikokuya , Kazuhiko Ikeuchi , Takeshi Watanabe , Norihide Kubota , Atsushi Igashira , Kenji Kobayashi , Ryota Tsukahara
发明人： Hidejirou Daikokuya , Kazuhiko Ikeuchi , Takeshi Watanabe , Norihide Kubota , Atsushi Igashira , Kenji Kobayashi , Ryota Tsukahara
IPC分类号： G06F11/00 , G06F11/10 , G06F11/07 , G06F11/20
CPC分类号： G06F11/1092 , G06F11/0727 , G06F11/076 , G06F11/0772 , G06F11/2094
摘要： A control device manages a plurality of storage devices so that data to be recorded is redundantly recorded in different storage devices. An error monitoring unit monitors an occurrence of an error in each of the plurality of storage devices to register information indicative of error occurrence conditions in an error information storage unit for each storage device. When the use of one of the plurality of storage devices is stopped, a rebuild controller determines a timing to perform rebuild processing based on past error occurrence conditions in the storage devices other than the one storage device of the plurality of storage devices by referring to information registered in the error information storage unit.
摘要翻译：控制装置管理多个存储装置，使得要记录的数据被冗余地记录在不同的存储装置中。错误监视单元监视多个存储设备中的每一个中的错误的发生，以在每个存储设备的错误信息存储单元中注册表示错误发生状况的信息。当停止使用多个存储装置中的一个时，重建控制器通过参考信息，基于多个存储装置中的一个存储装置以外的存储装置中的过去的错误发生状况来确定执行重建处理的定时登记在错误信息存储单元中。

9. 发明授权

US09028461B2 Pull-on wear article and method for producing the same 有权
标题翻译：穿戴物品及其制造方法
公开(公告)号：US09028461B2
公开(公告)日：2015-05-12
申请号：US13976847
申请日：2011-12-22
申请人： Kenji Kobayashi , Hayami Ishikawa , Junichi Yamashita
发明人： Kenji Kobayashi , Hayami Ishikawa , Junichi Yamashita
IPC分类号： A61F13/496 , A61F13/514 , A61F13/49 , A61F13/15
CPC分类号： A61F13/49012 , A61F13/15593 , A61F13/15699 , A61F13/49011 , A61F13/4902 , A61F13/496 , Y10T156/1064
摘要： A pull-on wear article having a front portion that is adapted to be worn around the front side of a wearer, a crotch portion that is adapted to be worn along the wearer's crotch region, and a rear portion that is adapted to be worn around the wearer's rear side, which is formed into a pants form by bonding lateral side edges of the front portion and lateral side edges of the rear portion, wherein the front portion and the rear portion are each constituted by an outer cover in which an inner layer material and an outer layer material are laminated, the outer cover has plural single layer areas that are formed of the inner layer material or the outer layer material at intervals in the direction of length of the outer cover, and the laminate areas where the inner layer material and outer layer material are laminated have elasticity in the waist-surrounding direction of the outer cover.
摘要翻译：具有适于佩戴在穿戴者的前侧的前部的穿着物品，适于沿着穿着者裆部区域佩戴的裆部和适于佩戴在周围的后部穿戴者的后侧通过粘合后部的前部和侧边缘的侧边缘而形成裤形，其中前部和后部各自由外盖构成，其中内层材料和外层材料层叠，外盖具有由外层材料或外层材料沿着外盖的长度方向间隔地形成的多个单层区域，其中内层层压材料和外层材料在外罩的腰围方向具有弹性。

10. 发明授权

US08930748B2 Storage apparatus and controller 有权
标题翻译：存储设备和控制器
公开(公告)号：US08930748B2
公开(公告)日：2015-01-06
申请号：US13371503
申请日：2012-02-13
申请人： Kazuhiko Ikeuchi , Hidejirou Daikokuya , Chikashi Maeda , Norihide Kubota , Atsushi Igashira , Kenji Kobayashi , Ryouta Tsukahara
发明人： Kazuhiko Ikeuchi , Hidejirou Daikokuya , Chikashi Maeda , Norihide Kubota , Atsushi Igashira , Kenji Kobayashi , Ryouta Tsukahara
IPC分类号： G06F11/00 , G11B27/36 , G11B27/00 , G06F11/20
CPC分类号： G11B27/36 , G06F11/2082 , G06F11/2094 , G11B27/002
摘要： A storage apparatus includes a plurality of first storage mediums in which data is redundantly stored and a controller. The controller includes a formatting section which performs formatting in each of the plurality of first storage mediums, a detection section which detects a failure that has occurred in the plurality of first storage mediums, a control section which makes the formatting section stop the formatting at the time of the detection of the failure by the detection section and which rebuilds the data stored in the plurality of first storage mediums in which the failure has occurred in a second storage medium other than the plurality of first storage mediums, and a rebuild processing section which rebuilds the data stored in the plurality of first storage mediums in the second storage medium in accordance with instructions from the control section.
摘要翻译：存储装置包括冗余存储数据的多个第一存储介质和控制器。控制器包括格式化部分，其在多个第一存储介质中的每一个中执行格式化;检测部分，其检测在多个第一存储介质中发生的故障;控制部分，其使格式化部分停止在检测部分检测到故障的时间，以及重建存储在其中发生故障的多个第一存储介质中的数据在除了多个第一存储介质之外的第二存储介质中的数据;以及重建处理部分，根据来自控制部分的指令重建存储在第二存储介质中的多个第一存储介质中的数据。

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