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1. 发明授权

US4469593A Blood purification apparatus 失效
标题翻译：血液净化装置
公开(公告)号：US4469593A
公开(公告)日：1984-09-04
申请号：US473574
申请日：1983-03-09
申请人： Toshikazu Ishihara , Tomoyuki Kitano , Kenji Maeda , Toru Shinzato
发明人： Toshikazu Ishihara , Tomoyuki Kitano , Kenji Maeda , Toru Shinzato
IPC分类号： A61M1/16 , A61M1/34 , A61M1/36 , B01D13/00
CPC分类号： A61M1/16 , A61M1/34 , A61M1/3406 , A61M1/3427 , A61M1/3437 , A61M1/3451 , A61M1/3609 , A61M1/361 , A61M1/3669 , A61M1/342
摘要： A blood purification apparatus includes an extracorporeal circulation system, a blood purifier provided in the system for purifying blood by dialysis or filtration through a semipermeable membrane, a circulation blood volume measuring instrument for measuring changes in a circulating blood volume within a patient's body, a control section comprising a memory for storing a program for a pattern of changes in the circulating blood volume during blood purification, the program being matched to the condition of a patient, and a regulator connected to the extracorporeal circulation system and the control section, for controlling the circulating blood volume, the regulator being controlled by the control section on the basis of the circulating blood volume measured during blood purification and the programmed amount. In this apparatus, optimum blood purification is carried out while maintaining the circulating blood volume at a prescribed level.
摘要翻译：一种血液净化装置，包括体外循环系统，通过半透膜进行透析或过滤而提供血液净化的血液净化装置，用于测定患者体内的循环血液量的变化的循环血液量测定装置，该部分包括用于存储用于在血液净化期间循环血液量的变化模式的程序的存储器，该程序与患者的状况相匹配，以及连接到体外循环系统和控制部分的调节器，用于控制循环血液量，调节器由控制部分根据血液净化期间测量的循环血液量和编程量控制。在该装置中，在将循环血量保持在规定水平的同时进行最佳的血液净化。

2. 发明授权

US08950027B2 Respiratory tract widening tool and respiratory tract widening unit provided therewith 有权
标题翻译：呼吸道加宽工具和呼吸道加宽单元
公开(公告)号：US08950027B2
公开(公告)日：2015-02-10
申请号：US13518140
申请日：2010-12-21
申请人： Keiichi Yamamoto , Yuzuru Kitahara , Yasuyo Maruyama , Toru Shinzato
发明人： Keiichi Yamamoto , Yuzuru Kitahara , Yasuyo Maruyama , Toru Shinzato
IPC分类号： A61F5/56
CPC分类号： A61F5/56 , A61F5/055
摘要： A respiratory tract widening tool capable of reliably managing a respiratory tract in a supine posture and freely changing the posture, and a respiratory tract widening unit provided therewith are provided.
摘要翻译：一种呼吸道加宽工具，其能够以仰卧姿态可靠地管理呼吸道并且自由地改变姿势，并且提供了一种呼吸道加宽单元。

3. 发明授权

US08419646B2 Blood pressure estimation apparatus and blood pressure estimation method 有权
标题翻译：血压估计装置及血压估计方法
公开(公告)号：US08419646B2
公开(公告)日：2013-04-16
申请号：US12935741
申请日：2009-04-09
申请人： Masatoshi Saito , Sakae Omura , Toru Shinzato
发明人： Masatoshi Saito , Sakae Omura , Toru Shinzato
IPC分类号： A61B5/02
CPC分类号： A61B5/021 , A61B5/02108 , A61B5/7239 , A61B7/04 , A61M1/16 , A61M1/3639 , A61M2230/04
摘要： To provide a non-invasive blood pressure estimation apparatus, which can accurately estimate systolic blood pressure from blood flow sound of a dialysis patient and continuously estimate systolic blood pressure by continuously picking up the blood flow sound. A blood pressure estimation apparatus creates a standard pulse curve by relating a start point and end point of a rising phase of a pulse wave to diastolic blood pressure and systolic blood pressure, respectively, creates a correspondence curve between blood flow sound power and estimated blood pressure by contrasting the standard pulse curve with the blood flow sound power curve obtained from blood flow sound at a shut site, with the two curves plotted on the same time axis, derives a systolic blood pressure estimation linear function from the correspondence curve, inputs a measured maximum value of the blood flow sound power into the linear function, and thereby estimates systolic blood pressure.
摘要翻译：提供可以准确地估计透析患者的血流声音的收缩压的无创血压估计装置，并通过连续地取出血流声来连续地估计收缩压。血压估计装置通过将脉搏波的上升相位的起点和终点分别与舒张压和收缩压相关联来创建标准脉搏曲线，从而产生血流声功率与估计血压之间的对应曲线通过将标准脉冲曲线与从关闭位置的血流声音获得的血流声功率曲线进行对比，并将两条曲线绘制在同一时间轴上，从对应曲线得到收缩压估计线性函数，输入测量值血流声功率的最大值进入线性函数，从而估计收缩压。

4. 发明授权

US5011607A Hemodiafiltration system 失效
标题翻译：血液透析过滤系统
公开(公告)号：US5011607A
公开(公告)日：1991-04-30
申请号：US534221
申请日：1990-06-07
申请人： Toru Shinzato
发明人： Toru Shinzato
IPC分类号： A61M1/14 , A61M1/16 , A61M1/34 , B01D61/24 , B01D61/28 , B01D61/30 , B01D61/32 , B01D61/58
CPC分类号： B01D61/58 , A61M1/16 , A61M1/1649 , A61M1/3427 , A61M1/3413 , B01D61/243 , Y10S210/929
摘要： A hemodiafiltration system which enables concurrent performance, in a single system, of hemodialysis and hemofiltration includes a dialyzer, consisting of a casing and at least one semipermeable membrane accommodated therein for dialyzing and purifying body fluid such as blood, plasma, etc., through contacting of the body fluid and dialyzate via the semipermeable membrane, and pumps for causing the dialyzate to flow through the dialyzer. A controller repeatedly changes the difference between the inflow amount of the dialyzate into the dialyzer per unit time and the outflow amount of the same from the dialyzer per unit time from a positive value to a negative value and then from negative to positive, whereby the repeated operation of taking or sucking out aqueous component or constituent and accompanying waste molecules from the body fluid followed by infusing or forcing a compensatory amount of dialyzate into the body fluid is made possible.
摘要翻译：一种血液透析过滤系统，其能够在单一系统中同时进行血液透析和血液滤过，包括透析器，包括壳体和容纳在其中的至少一个半透膜，用于通过接触透析和净化体液，例如血液，血浆等的体液和通过半透膜的透析液，以及用于使透析液流过透析器的泵。控制器将每单位时间的透析器的透析液的流入量与透析器的每单位时间的流出量从正值重复变化为负值，然后从负值变化为正，由此重复从体液中取出或吸出含水组分或组分以及伴随的废物分子，然后将补偿量的透析液注入体液中的操作成为可能。

5. 发明申请

US20130158461A1 HEMODIALYSIS SYSTEM 有权
标题翻译： HEMODIALYSIS系统
公开(公告)号：US20130158461A1
公开(公告)日：2013-06-20
申请号：US13808288
申请日：2011-07-14
申请人： Masatomi Sasaki , Toru Shinzato , Masayo Maruyama , Masamiki Miwa
发明人： Masatomi Sasaki , Toru Shinzato , Masayo Maruyama , Masamiki Miwa
IPC分类号： A61M1/30
CPC分类号： A61M1/30 , A61M1/16 , A61M1/1613 , A61M1/3609
摘要： A hemodialysis system includes a body fluid volume calculating unit, a dialysis condition input unit with which blood flow velocity and dialysis fluid flow velocity in hemodialysis treatment performed after specific hemodialysis treatment can be input and input values of the blood flow velocity and the dialysis fluid flow velocity can be adjusted, a dialysis dose calculating unit configured to calculate, when the blood flow velocity and the dialysis fluid flow velocity are input to the dialysis condition input unit, by analyzing a mathematical model concerning urea kinetics, a dialysis dose of the hemodialysis treatment from the input blood flow velocity and the input dialysis fluid flow velocity, a body fluid volume calculated by the body fluid volume calculating unit, and the like, and a dialysis dose display unit configured to display the hemodialysis dose calculated by the dialysis dose calculating unit.
摘要翻译：血液透析系统包括：体液体积计算部，透析条件输入部，能够输入在特定血液透析治疗后进行的血液透析治疗时的血流速度和透析液流速，血流速度和透析液流量的输入值可以调节速度，透析剂量计算单元被配置为当血液流速和透析液流速输入到透析条件输入单元时，通过分析关于尿素动力学的数学模型，计算血液透析治疗的透析剂量根据输入血流速度和输入透析液流速，由体液量计算单元计算的体液体积等，以及透析剂量显示单元，其被配置为显示由透析剂量计算单元计算出的血液透析剂量。

6. 发明申请

US20110125033A1 BLOOD PRESSURE ESTIMATION APPARATUS AND BLOOD PRESSURE ESTIMATION METHOD 有权
标题翻译：血压估计装置和血压估计方法
公开(公告)号：US20110125033A1
公开(公告)日：2011-05-26
申请号：US12935741
申请日：2009-04-09
申请人： Masatoshi Saito , Sakae Omura , Toru Shinzato
发明人： Masatoshi Saito , Sakae Omura , Toru Shinzato
IPC分类号： A61B5/021
CPC分类号： A61B5/021 , A61B5/02108 , A61B5/7239 , A61B7/04 , A61M1/16 , A61M1/3639 , A61M2230/04
摘要： [Problem to be Solved] To provide a non-invasive blood pressure estimation apparatus which can accurately estimate systolic blood pressure from blood flow sound of a dialysis patient and can continuously estimate systolic blood pressure by continuously picking up the blood flow sound of the subject.[Solution] A blood pressure estimation apparatus creates a standard pulse curve by relating a start point and end point of a rising phase of a pulse wave to diastolic blood pressure and systolic blood pressure, respectively, creates a correspondence curve between blood flow sound power and estimated blood pressure by contrasting the standard pulse curve with the blood flow sound power curve obtained from blood flow sound at a shut site, with the two curves plotted on the same time axis, derives a systolic blood pressure estimation linear function from the correspondence curve, inputs a measured maximum value of the blood flow sound power into the linear function, and thereby estimates systolic blood pressure.
摘要翻译： [待解决的问题]提供一种能够从透析患者的血流声音准确地估计收缩压的无创血压估计装置，能够通过连续地取出对象的血流声音来连续地估计收缩压。 [解决方案]血压估计装置通过将脉搏波的上升相位的起始点和终点分别与舒张压和收缩压相关联来创建标准脉搏曲线，从而产生血流声功率与通过将标准脉搏曲线与在关闭位置处的血流声音获得的血流声功率曲线进行对比，并将两条曲线绘制在同一时间轴上，从对应曲线得出收缩压估计线性函数，将测得的血流声功率的最大值输入线性函数，从而估计收缩压。

7. 发明授权

US09199024B2 Hemodialysis system 有权
标题翻译：血液透析系统
公开(公告)号：US09199024B2
公开(公告)日：2015-12-01
申请号：US13808288
申请日：2011-07-14
申请人： Masatomi Sasaki , Toru Shinzato , Masayo Maruyama , Masamiki Miwa
发明人： Masatomi Sasaki , Toru Shinzato , Masayo Maruyama , Masamiki Miwa
IPC分类号： A61M1/16 , A61M1/30 , A61M1/36
CPC分类号： A61M1/30 , A61M1/16 , A61M1/1613 , A61M1/3609
摘要： A hemodialysis system includes a body fluid volume calculating unit, a dialysis condition input unit with which blood flow velocity and dialysis fluid flow velocity in hemodialysis treatment performed after specific hemodialysis treatment can be input and input values of the blood flow velocity and the dialysis fluid flow velocity can be adjusted, a dialysis dose calculating unit configured to calculate, when the blood flow velocity and the dialysis fluid flow velocity are input to the dialysis condition input unit, by analyzing a mathematical model concerning urea kinetics, a dialysis dose of the hemodialysis treatment from the input blood flow velocity and the input dialysis fluid flow velocity, a body fluid volume calculated by the body fluid volume calculating unit, and the like, and a dialysis dose display unit configured to display the hemodialysis dose calculated by the dialysis dose calculating unit.
摘要翻译：血液透析系统包括：体液体积计算部，透析条件输入部，能够输入在特定血液透析治疗后进行的血液透析治疗时的血流速度和透析液流速，血流速度和透析液流量的输入值可以调节速度，透析剂量计算单元被配置为当血液流速和透析液流速输入到透析条件输入单元时，通过分析关于尿素动力学的数学模型，计算血液透析治疗的透析剂量根据输入血流速度和输入透析液流速，由体液量计算单元计算的体液体积等，以及透析剂量显示单元，其被配置为显示由透析剂量计算单元计算出的血液透析剂量。

8. 发明申请

US20130025058A1 RESPIRATORY TRACT WIDENING TOOL AND RESPIRATORY TRACT WIDENING UNIT PROVIDED THEREWITH 有权
标题翻译：呼吸辅助工具及呼吸辅助装置
公开(公告)号：US20130025058A1
公开(公告)日：2013-01-31
申请号：US13518140
申请日：2010-12-21
申请人： Keiichi Yamamoto , Yuzuru Kitahara , Yasuyo Maruyama , Toru Shinzato
发明人： Keiichi Yamamoto , Yuzuru Kitahara , Yasuyo Maruyama , Toru Shinzato
IPC分类号： A61F5/56 , A47G9/10
CPC分类号： A61F5/56 , A61F5/055
摘要： A respiratory tract widening tool capable of reliably managing a respiratory tract in a supine posture and freely changing the posture, and a respiratory tract widening unit provided therewith are provided.
摘要翻译：一种呼吸道加宽工具，其能够以仰卧姿态可靠地管理呼吸道并且自由地改变姿势，并且提供具有呼吸道加宽单元。

9. 发明申请

US20060155318A1 Hole-forming pin for inserting indwelling needle and jig for installing the pin 审中-公开
标题翻译：用于插入留置针的孔形销和用于安装销的夹具
公开(公告)号：US20060155318A1
公开(公告)日：2006-07-13
申请号：US10522197
申请日：2003-07-24
申请人： Toru Shinzato , Shigeki Toma , Yoshihiko Sano , Toshiaki Masuda , Futoshi Yamaguchi , Kazuyoshi Harada , Nobuo Takagi , Masahisa Tanimoto
发明人： Toru Shinzato , Shigeki Toma , Yoshihiko Sano , Toshiaki Masuda , Futoshi Yamaguchi , Kazuyoshi Harada , Nobuo Takagi , Masahisa Tanimoto
IPC分类号： A61B17/34
CPC分类号： A61M25/0637
摘要： A pin for forming a hole for inserting an indwelling needle for minimize a load exerted to a living body, and a jig for installing the hole-forming pin from a skin surface are provided. The pin for forming a hole for inserting an indwelling needle A for holding the indwelling pin from the skin surface to a blood vessel includes a column-shaped insertion part 1 having a curved surface at the distal end thereof, an insertion stop part 2 provided at the proximal end of the insertion part 1, and wings 4 connected to the insertion stop part 2 via flexible joint branches 3, and a jig for mounting the hole-forming pin A includes a main body 6, a sliding body 7 that is built in the main body 6 for sliding in the longitudinal direction of the main body, supporting means 10 for supporting the indwelling needle insertion hole-forming pin at the distal end(s) of the sliding body 7 and/or the main body 6 of the jig for installing the pin are provided, and pin for forming a hole for inserting an indwelling needle A is installing from the skin surface toward the blood vessel by the sliding movement of the sliding body 7.
摘要翻译：用于形成用于插入留置针的孔以最小化施加到生物体的负载的销和用于从皮肤表面安装孔形销的夹具。用于将用于将留置针保持在皮肤表面的留置针A的孔形成用于血管的销包括：在其前端具有弯曲表面的柱状插入部1，设置在其上的插入停止部2 插入部1的近端，以及通过挠性接头分支3与插入止挡部2连接的翼部4，并且用于安装孔形销A的夹具包括主体6，内置的滑动体7 用于在主体的纵向滑动的主体6，用于在滑动体7的远端和/或夹具的主体6上支撑留置针插入孔形成销的支撑装置10 设置销，并且通过滑动体7的滑动，从皮肤表面向血管安装用于形成用于插入留置针A的孔的销。

10. 发明授权

US5370123A Blood clarification apparatus 失效
标题翻译：血液澄清仪
公开(公告)号：US5370123A
公开(公告)日：1994-12-06
申请号：US147445
申请日：1993-11-05
申请人： Toru Shinzato
发明人： Toru Shinzato
IPC分类号： A61B5/00 , A61B5/0215 , A61M1/14 , A61M1/16 , A61M1/36 , A61M25/00
CPC分类号： A61M1/3639 , A61B5/0215 , A61M1/16 , A61M2025/0003 , A61M2205/3344 , A61M2205/3351 , A61M2230/30
摘要： A blood clarification device wherein a means for measuring blood pressure comprises (a) a needle-detector which is much thinner than the puncture needle and capable of being smoothly inserted into a blood vessel from outside through an inner aperture of the puncture needle, (b) an insertion aperture, for allowing fluid-tight insertion of the needle-detector, positioned on a wall of the blood supply passage in the vicinity of the puncture needle, and (c) a pressure transducer for detecting the blood pressure inside the blood vessel transmitted thereto via the needle-detector. In a blood clarification apparatus of the present invention, blood pressure inside a blood vessel is transmitted to a pressure transducer via a needle-detector during dialysis/filtration operation and blood pressure of a patient is detected continuously and automatically by the pressure transducer. A counterplan such as control of water-removing-rate or supplying-supplementary-fluid-rate based on the detected blood pressure is automatically carried out, so that safety of dialysis/filtration operation can be effectively improved.
摘要翻译：一种血液净化装置，其中，用于测量血压的装置包括（a）比所述穿刺针更薄的针检测器，并且能够从外部通过穿刺针的内孔平滑地插入血管，（b ）插入孔，用于允许位于穿刺针附近的血液供应通道的壁上的针检测器的流体密封插入，以及（c）用于检测血管内的血压的压力传感器通过针检测器向其传送。在本发明的血液净化装置中，通过透析·过滤动作，通过针检测器将血管内的血压传递给压力传感器，并通过压力传感器自动检测患者的血压。自动执行基于检测到的血压控制除水率或补充液体比率的计划，从而可以有效地提高透析/过滤操作的安全性。

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