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1. 发明授权

US08847166B2 Imaging device using gamma rays, image signal processor, and image processing method for gamma ray measurement data 有权
标题翻译：使用γ射线的成像装置，图像信号处理器和用于伽马射线测量数据的图像处理方法
公开(公告)号：US08847166B2
公开(公告)日：2014-09-30
申请号：US13991386
申请日：2011-11-15
申请人： Tomonori Fukuchi , Shinji Motomura , Shin'ichiro Takeda , Shuichi Enomoto
发明人： Tomonori Fukuchi , Shinji Motomura , Shin'ichiro Takeda , Shuichi Enomoto
IPC分类号： G06T7/00 , G01T1/29 , G01T1/164
CPC分类号： G06T7/0012 , A61B6/037 , G01T1/1642 , G01T1/2985
摘要： To simultaneously image a plurality types of tracer molecules for a Compton image and a PET image. Provided is an imaging device comprising: a first Compton camera (10) for receiving one gamma ray emitted from an imaging target (900) administered by first probe having positron emitting nuclei and second probe having gamma ray emission nuclei; and a second Compton camera (20) which is arranged opposite to the first Compton camera (10) and receives another gamma ray emitted from the imaging target (900). The imaging device is also provided with: an imaging processor for distinguishing and reconstructing a PET image and a Compton image in accordance with the combination of the Compton cameras which detected the gamma rays; and a display for displaying the PET image and the Compton image in association respectively with the first and the second probes.
摘要翻译：为了同时成像用于康普顿图像和PET图像的多种类型的示踪剂分子。提供了一种成像装置，包括：第一康普顿相机（10），用于接收从具有正电子发射核的第一探针施加的成像靶（900）发射的一个伽马射线，以及具有伽马射线发射核的第二探针; 以及第二康普顿相机（20），其布置成与所述第一康普普森相机（10）相对，并且接收从所述成像目标（900）发射的另一伽马射线。成像装置还具有：成像处理器，用于根据检测到伽马射线的康普顿相机的组合来区分和重建PET图像和康普顿图像; 以及用于显示分别与第一和第二探针相关联的PET图像和Compton图像的显示器。

2. 发明申请

US20130334429A1 IMAGING DEVICE USING GAMMA RAYS, IMAGE SIGNAL PROCESSOR, AND IMAGE PROCESSING METHOD FOR GAMMA RAY MEASUREMENT DATA 有权
标题翻译：使用伽马射线成像装置，图像信号处理器和用于伽马射线测量数据的图像处理方法
公开(公告)号：US20130334429A1
公开(公告)日：2013-12-19
申请号：US13991386
申请日：2011-11-15
申请人： Tomonori Fukuchi , Shinji Motomura , Shin'ichiro Takeda , Shuichi Enomoto
发明人： Tomonori Fukuchi , Shinji Motomura , Shin'ichiro Takeda , Shuichi Enomoto
IPC分类号： G06T7/00 , G01T1/29
CPC分类号： G06T7/0012 , A61B6/037 , G01T1/1642 , G01T1/2985
摘要： To simultaneously image a plurality types of tracer molecules for a Compton image and a PET image. Provided is an imaging device comprising: a first Compton camera (10) for receiving one gamma ray emitted from an imaging target (900) administered by first probe having positron emitting nuclei and second probe having gamma ray emission nuclei; and a second Compton camera (20) which is arranged opposite to the first Compton camera (10) and receives another gamma ray emitted from the imaging target (900). The imaging device is also provided with: an imaging processor for distinguishing and reconstructing a PET image and a Compton image in accordance with the combination of the Compton cameras which detected the gamma rays; and a display for displaying the PET image and the Compton image in association respectively with the first and the second probes.
摘要翻译：为了同时成像用于康普顿图像和PET图像的多种类型的示踪剂分子。提供了一种成像装置，包括：第一康普顿相机（10），用于接收从具有正电子发射核的第一探针施加的成像靶（900）发射的一个伽马射线，以及具有伽马射线发射核的第二探针; 以及第二康普顿相机（20），其布置成与所述第一康普普森相机（10）相对，并且接收从所述成像目标（900）发射的另一伽马射线。成像装置还具有：成像处理器，用于根据检测到伽马射线的康普顿相机的组合来区分和重建PET图像和康普顿图像; 以及用于显示分别与第一和第二探针相关联的PET图像和Compton图像的显示器。

3. 发明授权

US08227759B2 Semiconductor radiation detection apparatus 有权
标题翻译：半导体辐射检测仪
公开(公告)号：US08227759B2
公开(公告)日：2012-07-24
申请号：US12607348
申请日：2009-10-28
申请人： Tomonori Fukuchi , Shinji Motomura , Shuichi Enomoto , Yousuke Kanayama
发明人： Tomonori Fukuchi , Shinji Motomura , Shuichi Enomoto , Yousuke Kanayama
IPC分类号： G01T1/24
CPC分类号： G01T1/2928
摘要： The apparatus has an energy calculation section 32 that calculates energy deposit values of interactions based on signals obtained from segmented electrodes 11, 12 provided on two opposite surfaces of a semiconductor crystal, a reference waveform storing section 33 that stores beforehand waveforms that will be obtained from the segmented electrodes when a single interaction occurs for multiple positions in the crystal, a waveform synthesis section 34 that synthesizes reference waveforms corresponding to arbitrary two points in the crystal as candidate points of interaction at a ratio equal to a ratio of their energy deposit values, and a comparison section 35 that compares a measured waveform and the synthesized waveforms. The candidate points from which the synthesized waveform most similar to the measured waveform is obtained is determined to be the positions of interactions. Thus, even in cases where multiple interactions occur, the positions of the interactions can be detected.
摘要翻译：该装置具有能量计算部32，该能量计算部32基于从设置在半导体晶体的两个相对面的分割电极11,12获得的信号来计算相互作用的能量存储值，基准波形存储部33预先存储将从当晶体中的多个位置发生单个相互作用时的分段电极;波形合成部分34，其以与等于其能量沉积值的比率的比率合成与晶体中的任意两个点相对应的参考波形作为候选交互点，比较测量波形和合成波形的比较部分35。获得与测量波形最相似的合成波形的候选点被确定为相互作用的位置。因此，即使在发生多次相互作用的情况下，也可以检测相互作用的位置。

4. 发明授权

US09024262B2 Pet device and imaging method therefor 有权
标题翻译：宠物装置及其成像方法
公开(公告)号：US09024262B2
公开(公告)日：2015-05-05
申请号：US14236847
申请日：2012-08-01
申请人： Tomonori Fukuchi , Shuichi Enomoto
发明人： Tomonori Fukuchi , Shuichi Enomoto
IPC分类号： G01T1/20 , G01T1/29 , A61B6/03
CPC分类号： G01T1/2985 , A61B6/037
摘要： In the present invention, to conduct multiple molecular imaging in a PET device, both a first probe and a second probe, each of which has a nuclide that emits unique gamma rays as a result of gamma decay after beta decay, are administered to a subject to be imaged, and then the image capturing is performed by a multiple probe PET device (100). The multiple probe PET device (100) is provided with a group of PET gamma ray detectors (10) and an energy-resolving gamma ray detector (20), and, when an imaging processor (30) executes image reconstruction based on a pair-annihilation detection signal from the group of PET gamma ray detectors (10), images are reconstructed differently according to the energy values of the unique gamma rays. Imaging can also be carried out using a nuclide that does not emit any unique gamma ray and a nuclide that emits a unique gamma ray.
摘要翻译：在本发明中，为了在PET装置中进行多分子成像，第一探针和第二探针两者均具有作为β衰变后伽马衰变的结果发射独特的γ射线的核素，进行成像，然后通过多探针PET装置（100）进行图像拍摄。多探针PET装置（100）设置有一组PET伽马射线检测器（10）和能量分辨伽马射线检测器（20），并且当成像处理器（30）基于成对处理器执行图像重建时，来自PET伽马射线探测器组（10）的湮灭检测信号根据独特伽马射线的能量值不同地重建图像。成像还可以使用不发射任何独特的伽马射线的核素和发射独特伽玛射线的核素进行。

5. 发明申请

US20140175293A1 PET DEVICE AND IMAGING METHOD THEREFOR 有权
标题翻译： PET装置及其成像方法
公开(公告)号：US20140175293A1
公开(公告)日：2014-06-26
申请号：US14236847
申请日：2012-08-01
申请人： Tomonori Fukuchi , Shuichi Enomoto
发明人： Tomonori Fukuchi , Shuichi Enomoto
IPC分类号： G01T1/29 , A61B6/03
CPC分类号： G01T1/2985 , A61B6/037
摘要： In the present invention, to conduct multiple molecular imaging in a PET device, both a first probe and a second probe, each of which has a nuclide that emits unique gamma rays as a result of gamma decay after beta decay, are administered to a subject to be imaged, and then the image capturing is performed by a multiple probe PET device (100). The multiple probe PET device (100) is provided with a group of PET gamma ray detectors (10) and an energy-resolving gamma ray detector (20), and, when an imaging processor (30) executes image reconstruction based on a pair-annihilation detection signal from the group of PET gamma ray detectors (10), images are reconstructed differently according to the energy values of the unique gamma rays. Imaging can also be carried out using a nuclide that does not emit any unique gamma ray and a nuclide that emits a unique gamma ray.
摘要翻译：在本发明中，为了在PET装置中进行多分子成像，第一探针和第二探针两者均具有作为β衰变后伽马衰变的结果发射独特的γ射线的核素，进行成像，然后通过多探针PET装置（100）进行图像拍摄。多探针PET装置（100）设置有一组PET伽马射线检测器（10）和能量分辨伽马射线检测器（20），并且当成像处理器（30）基于成对处理器执行图像重建时，来自PET伽马射线探测器组（10）的湮灭检测信号根据独特伽马射线的能量值不同地重建图像。成像还可以使用不发射任何独特的伽马射线的核素和发射独特伽玛射线的核素进行。

6. 发明申请

US20140142016A1 SKIN CLEANSING AGENT COMPOSITION 有权
标题翻译：皮肤清洁剂组合物
公开(公告)号：US20140142016A1
公开(公告)日：2014-05-22
申请号：US14130792
申请日：2012-07-03
申请人： Atsushi Tomokuni , Tomonori Fukuchi
发明人： Atsushi Tomokuni , Tomonori Fukuchi
IPC分类号： A61K8/37 , A61K8/34 , A61K8/81 , A61Q19/10
CPC分类号： A61K8/37 , A61K8/34 , A61K8/345 , A61K8/8147 , A61K8/8158 , A61K8/8182 , A61K8/86 , A61Q1/14 , A61Q19/10
摘要： A skin cleansing agent composition of the present invention contains an isotropic liquid phase, which is a bicontinuous structure, and containing: 15 to 30 mass % of a nonionic surfactant having HLB of higher than 9 and equal to or lower than 20; 1 to 15 mass % of a nonionic surfactant having HLB of equal to or higher than 5 and equal to or lower than 9; 10 to 40 mass % of an oil agent exhibiting a viscosity at 30 degrees C. of equal to or lower than 30 mPa·s; 10 to 40 mass % of a water-soluble solvent having 3 or more of hydroxyl groups in single molecule; 10 to 30 mass % of a water-soluble solvent having 1 or 2 hydroxyl group(s) in single molecule; 0.05 to 1.0 mass % of a water-soluble polymer containing (meta)acrylic acid as a configuration unit and/or an acryloyl methyl taurate-vinylpyrrolidone copolymer; 0.001 to 2.0 mass % of a water-soluble inorganic salt and/or an organic salt having 1 to 8 carbon atoms; and water.
摘要翻译：本发明的皮肤清洁剂组合物含有双相结构的各向同性液相，含有15〜30质量％的HLB在9以上且20以下的非离子表面活性剂; 1〜15质量％的HLB为5以上且9以下的非离子表面活性剂; 10〜40质量％的在30℃下的粘度为30mPa·s以下的油剂; 10〜40质量％的单分子中具有3个以上羟基的水溶性溶剂; 10〜30质量％的单分子中具有1个或2个羟基的水溶性溶剂; 0.05质量％含有（甲基）丙烯酸作为结构单元的水溶性聚合物和/或丙烯酰甲基牛磺酸乙烯基吡咯烷酮共聚物; 0.001〜2.0质量％的水溶性无机盐和/或碳原子数1〜8的有机盐; 和水。

7. 发明授权

US09072674B2 Skin cleansing agent composition 有权
标题翻译：皮肤清洁剂组成
公开(公告)号：US09072674B2
公开(公告)日：2015-07-07
申请号：US14130792
申请日：2012-07-03
申请人： Atsushi Tomokuni , Tomonori Fukuchi
发明人： Atsushi Tomokuni , Tomonori Fukuchi
IPC分类号： C11D1/66 , C11D1/825 , C11D3/18 , A61K8/34 , A61Q1/14 , A61K8/37 , A61K8/86 , A61Q19/10 , A61K8/81
CPC分类号： A61K8/37 , A61K8/34 , A61K8/345 , A61K8/8147 , A61K8/8158 , A61K8/8182 , A61K8/86 , A61Q1/14 , A61Q19/10
摘要： A skin cleansing agent composition of the present invention contains an isotropic liquid phase, which is a bicontinuous structure, and containing: 15 to 30 mass % of a nonionic surfactant having HLB of higher than 9 and equal to or lower than 20; 1 to 15 mass % of a nonionic surfactant having HLB of equal to or higher than 5 and equal to or lower than 9; 10 to 40 mass % of an oil agent exhibiting a viscosity at 30 degrees C. of equal to or lower than 30 mPa·s; 10 to 40 mass % of a water-soluble solvent having 3 or more of hydroxyl groups in single molecule; 10 to 30 mass % of a water-soluble solvent having 1 or 2 hydroxyl group(s) in single molecule; 0.05 to 1.0 mass % of a water-soluble polymer containing (meta)acrylic acid as a configuration unit and/or an acryloyl methyl taurate-vinylpyrrolidone copolymer; 0.001 to 2.0 mass % of a water-soluble inorganic salt and/or an organic salt having 1 to 8 carbon atoms; and water.
摘要翻译：本发明的皮肤清洁剂组合物含有双相结构的各向同性液相，含有15〜30质量％的HLB在9以上且20以下的非离子表面活性剂; 1〜15质量％的HLB为5以上且9以下的非离子表面活性剂; 10〜40质量％的在30℃下的粘度为30mPa·s以下的油剂; 10〜40质量％的单分子中具有3个以上羟基的水溶性溶剂; 10〜30质量％的单分子中具有1个或2个羟基的水溶性溶剂; 0.05质量％含有（甲基）丙烯酸作为结构单元的水溶性聚合物和/或丙烯酰甲基牛磺酸乙烯基吡咯烷酮共聚物; 0.001〜2.0质量％的水溶性无机盐和/或碳原子数为1〜8的有机盐; 和水。

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