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1. 发明申请

US20050084839A1 Method for selecting oocytes by using a response to LPA stimulation 审中-公开
标题翻译：通过使用对LPA刺激的反应来选择卵母细胞的方法
公开(公告)号：US20050084839A1
公开(公告)日：2005-04-21
申请号：US10876551
申请日：2004-06-28
申请人： Tomoko Takeshita , Takako Mizoguchi , Shuhei Hashiba , Jun Otomo
发明人： Tomoko Takeshita , Takako Mizoguchi , Shuhei Hashiba , Jun Otomo
IPC分类号： C12N15/09 , A01N1/02 , C12N5/00 , C12N5/075 , C12N5/10 , C12Q1/02
CPC分类号： C12N5/0612 , C12N5/0609
摘要： The selection of oocytes has largely relied on manual procedures, resulting in their lack of uniformity. Groups of oocytes are prepared and sorted, the current responses of these groups of oocytes upon exposure to lysophosphatidic acid (LPA) are measured, the response of G protein-coupled receptor (GPCR) is determined for each group of oocytes, and desirable groups of oocytes are selected on the basis of the response of GPCR. In this way, oocytes having a uniformly high response of GPCR can be selected.
摘要翻译：卵母细胞的选择在很大程度上取决于手工程序，导致其缺乏一致性。卵母细胞的组成和分选，测定了这些卵母细胞群暴露于溶血磷脂酸（LPA）后的当前反应，测定每组卵母细胞G蛋白偶联受体（GPCR）的反应，基于GPCR的反应选择卵母细胞。以这种方式，可以选择具有GPCR均匀高响应的卵母细胞。

2. 发明申请

US20130121879A1 Magnetic-Field Measurement Device 审中-公开
标题翻译：磁场测量装置
公开(公告)号：US20130121879A1
公开(公告)日：2013-05-16
申请号：US13810832
申请日：2011-07-19
申请人： Ryuzo Kawabata , Takako Mizoguchi , Akira Tsukamoto , Akihiko Kandori , Tomoko Yoshimura
发明人： Ryuzo Kawabata , Takako Mizoguchi , Akira Tsukamoto , Akihiko Kandori , Tomoko Yoshimura
IPC分类号： G01N33/543
CPC分类号： G01N33/54333 , G01N27/745
摘要： The disclosed magnetic immunoassay device, which performs magnetic immunoassays using antigen-antibody reactions, can perform speedy immunoassays without bound/free separation in the test samples. The device is also practical, being capable of stable magnetism measurement without magnetic shielding. The disclosed magnetic immunoassay device is provided with: an excitation coil that uses an AC magnetic field to magnetize a test sample containing a magnetic marker; a magnetism sensor that measures magnetism in the test sample and outputs a magnetism signal; and a displacement sensor for detecting changes in the distance between the test sample and the magnetism sensor. By optimally setting the bandwidth of a lock-in amplifier, which detects changes in the phase of the magnetism signal outputted by the magnetism sensor, and the rotational speed produced by a drive system, which moves the test sample at low speeds, the impact of environment magnetic noise is reduced, and correcting the magnetism signal using distance information obtained from the displacement sensor allows stable magnetism measurement.
摘要翻译：所公开的使用抗原 - 抗体反应进行磁性免疫测定的磁性免疫测定装置可以在测试样品中进行快速的免疫测定而无限制/自由分离。该装置也是实用的，能够在没有磁屏蔽的情况下进行稳定的磁测量。所公开的磁免疫测定装置具有：励磁线圈，其使用交流磁场来磁化含有磁性标记的测试样品; 磁传感器，其测量测试样品中的磁性并输出磁信号; 以及用于检测测试样本和磁传感器之间的距离变化的位移传感器。通过最佳地设置检测由磁传感器输出的磁信号的相位变化的锁定放大器的带宽和由低速移动测试样本的驱动系统产生的转速，环境磁噪声降低，并且使用从位移传感器获得的距离信息来校正磁信号，可以进行稳定的磁测量。

3. 发明申请

US20130085417A1 DEGREE OF HARDNESS MEASUREMENT SYSTEM AND DEGREE OF HARDNESS MEASUREMENT METHOD 有权
标题翻译：硬度测量系统的程度和硬度测量方法的程度
公开(公告)号：US20130085417A1
公开(公告)日：2013-04-04
申请号：US13559149
申请日：2012-07-26
申请人： Akihiko KANDORI , Kuniomi Ogata , Ryuzo Kawabata , Yuko Sano , Takako Mizoguchi
发明人： Akihiko KANDORI , Kuniomi Ogata , Ryuzo Kawabata , Yuko Sano , Takako Mizoguchi
IPC分类号： A61B5/103
CPC分类号： A61B5/103 , A61B5/0053 , A61B5/02007 , A61B5/442 , A61B2562/0219 , G01N2203/00 , G01N2203/0075 , G01N2203/0076
摘要： For measuring hardness of an object, a measurement apparatus is pushed against the object and a degree of hardness calculation system calculates hardness based on information from the measurement apparatus. The measurement apparatus includes an acceleration sensor which outputs first information of acceleration of a contact area of the measurement apparatus, and a second sensor, such as a magnetic sensor or a pressure sensor, which outputs second information based on pressure applied to the contact area. The degree of hardness calculation system generates a second-derivative waveform by twice differentiating a waveform based on the output of the second sensor, compares the second-derivative waveform and the information of acceleration from the acceleration sensor, and calculates hardness of the object based on the comparison result.
摘要翻译：为了测量物体的硬度，将测量装置推压到物体上，并且一定程度的硬度计算系统基于来自测量装置的信息来计算硬度。测量装置包括：加速度传感器，其输出测量装置的接触区域的加速度的第一信息;以及第二传感器，例如磁传感器或压力传感器，其基于施加到接触区域的压力输出第二信息。硬度计算系统通过基于第二传感器的输出对波形进行二次微分而产生二次微分波形，从加速度传感器比较二次微分波形和加速度信息，并基于比较结果。

4. 发明授权

US09468581B2 Compression depth calculation system and compression depth calculation method 有权
标题翻译：压缩深度计算系统和压缩深度计算方法
公开(公告)号：US09468581B2
公开(公告)日：2016-10-18
申请号：US13883765
申请日：2011-11-28
申请人： Akihiko Kandori , Kuniomi Ogata , Ryuzo Kawabata , Yuko Sano , Takako Mizoguchi
发明人： Akihiko Kandori , Kuniomi Ogata , Ryuzo Kawabata , Yuko Sano , Takako Mizoguchi
IPC分类号： A61H31/00 , A61B5/103 , A61B5/00
CPC分类号： A61H31/00 , A61B5/0053 , A61B5/103 , A61B5/4848 , A61H31/005 , A61H2201/5007 , A61H2201/5023 , A61H2201/5043 , A61H2201/5058 , A61H2201/5061 , A61H2201/5064 , A61H2201/5071 , A61H2201/5084 , A61H2201/5092 , A61H2203/04 , A61H2203/0443 , A61H2203/0456 , A61H2205/00 , A61H2205/08 , A61H2205/084 , A61H2230/04
摘要： A compression depth calculation system is configured to calculate the compression depth which is a magnitude of depression of the compressed object generated by the compression and includes a measuring apparatus to be mounted on the object, and a compression depth calculating apparatus is configured to calculate the compression depth on the basis of information from the measuring apparatus. The compression depth calculation apparatus calculates a coefficient of transformation on the basis of a second-order differential waveform created for the information acquired from a magnetic sensor and acceleration information acquired from an acceleration sensor, creates a displacement waveform of a compressed portion by multiplying the acquired information by the coefficient of transformation, and calculates the compression depth on the basis of the displacement waveform.
摘要翻译：压缩深度计算系统被配置为计算由压缩产生的压缩对象的压下量的压缩深度，并且包括要安装在对象上的测量装置，并且压缩深度计算装置被配置为计算压缩基于来自测量装置的信息的深度。压缩深度计算装置基于对从磁传感器获取的信息创建的二阶微分波形和从加速度传感器获取的加速度信息计算变换系数，通过将所获取的加权信息乘以压缩部分的位移波形信息，并根据位移波形计算压缩深度。

5. 发明授权

US09055893B2 Degree of hardness measurement system and degree of hardness measurement method 有权
标题翻译：硬度测量系统和硬度测量方法
公开(公告)号：US09055893B2
公开(公告)日：2015-06-16
申请号：US13559149
申请日：2012-07-26
申请人： Akihiko Kandori , Kuniomi Ogata , Ryuzo Kawabata , Yuko Sano , Takako Mizoguchi
发明人： Akihiko Kandori , Kuniomi Ogata , Ryuzo Kawabata , Yuko Sano , Takako Mizoguchi
IPC分类号： A61B5/117 , A61B5/103 , A61B5/00 , A61B5/02
CPC分类号： A61B5/103 , A61B5/0053 , A61B5/02007 , A61B5/442 , A61B2562/0219 , G01N2203/00 , G01N2203/0075 , G01N2203/0076
摘要： For measuring hardness of an object, a measurement apparatus is pushed against the object and a degree of hardness calculation system calculates hardness based on information from the measurement apparatus. The measurement apparatus includes an acceleration sensor which outputs first information of acceleration of a contact area of the measurement apparatus, and a second sensor, such as a magnetic sensor or a pressure sensor, which outputs second information based on pressure applied to the contact area. The degree of hardness calculation system generates a second-derivative waveform by twice differentiating a waveform based on the output of the second sensor, compares the second-derivative waveform and the information of acceleration from the acceleration sensor, and calculates hardness of the object based on the comparison result.
摘要翻译：为了测量物体的硬度，将测量装置推压到物体上，并且一定程度的硬度计算系统基于来自测量装置的信息来计算硬度。测量装置包括：加速度传感器，其输出测量装置的接触区域的加速度的第一信息;以及第二传感器，例如磁传感器或压力传感器，其基于施加到接触区域的压力输出第二信息。硬度计算系统通过基于第二传感器的输出对波形进行二次微分而产生二次微分波形，从加速度传感器比较二次微分波形和加速度信息，并基于比较结果。

6. 发明申请

US20130226049A1 COMPRESSION DEPTH CALCULATION SYSTEM AND COMPRESSION DEPTH CALCULATION METHOD 有权
标题翻译：压缩深度计算系统和压缩深度计算方法
公开(公告)号：US20130226049A1
公开(公告)日：2013-08-29
申请号：US13883765
申请日：2011-11-28
申请人： Akihiko Kandori , Kuniomi Ogata , Ryuzo Kawabata , Yuko Sano , Takako Mizoguchi
发明人： Akihiko Kandori , Kuniomi Ogata , Ryuzo Kawabata , Yuko Sano , Takako Mizoguchi
IPC分类号： A61H31/00
CPC分类号： A61H31/00 , A61B5/0053 , A61B5/103 , A61B5/4848 , A61H31/005 , A61H2201/5007 , A61H2201/5023 , A61H2201/5043 , A61H2201/5058 , A61H2201/5061 , A61H2201/5064 , A61H2201/5071 , A61H2201/5084 , A61H2201/5092 , A61H2203/04 , A61H2203/0443 , A61H2203/0456 , A61H2205/00 , A61H2205/08 , A61H2205/084 , A61H2230/04
摘要： It is an object to calculate a compression depth easily with high degree of accuracy. The present invention provides a compression depth calculation system 1000 configured to calculate the compression depth which is a magnitude of depression of the compressed object generated by the compression and includes a measuring apparatus 1 to be mounted on the object, and a compression depth calculating apparatus 2 configured to calculate the compression depth on the basis of information from the measuring apparatus 1. The compression depth calculation apparatus 2 calculates a coefficient of transformation on the basis of a second-order differential waveform created for the information acquired from a magnetic sensor 19 and acceleration information acquired from an acceleration sensor 13, creates a displacement waveform of a compressed portion by multiplying the acquired information by the coefficient of transformation, and calculates the compression depth on the basis of the displacement waveform.
摘要翻译：本发明的目的是以高精度计算压缩深度。本发明提供了一种压缩深度计算系统1000，其被配置为计算压缩深度，该压缩深度是由压缩产生的压缩对象的压下量，并且包括要安装在对象上的测量装置1和压缩深度计算装置2 被配置为基于来自测量装置1的信息来计算压缩深度。压缩深度计算装置2基于为从磁传感器19获取的信息创建的二阶差分波形和加速度来计算变换系数从加速度传感器13获取的信息通过将所获取的信息乘以变换系数来产生压缩部分的位移波形，并且基于位移波形来计算压缩深度。

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