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1. 发明申请

US20120088227A1 Devices and Process for Separating Plasma From a Blood Sample 审中-公开
标题翻译：从血液样品中分离血浆的装置和方法
公开(公告)号：US20120088227A1
公开(公告)日：2012-04-12
申请号：US13082646
申请日：2011-04-08
申请人： Tomas Gruebl , Michael Heinrich , Roger Sandoz , Emad Sarofim , Hans-Peter Wahl
发明人： Tomas Gruebl , Michael Heinrich , Roger Sandoz , Emad Sarofim , Hans-Peter Wahl
IPC分类号： B01D43/00 , C12Q1/70
CPC分类号： G01N33/491 , B01L3/5023 , B01L2200/028 , B01L2300/043 , B01L2300/0681 , B01L2300/069 , B01L2400/0406
摘要： The present invention pertains to a device for separating plasma from a blood sample comprising a stacked structure which is provided with a first portion including a separating member having a first surface for applying or receiving the blood sample, wherein the separating member is adapted to permit the passage of plasma but to inhibit the passage of cells, and a second portion including an absorptive member for absorbing the plasma, which has a second surface in contact with the separating member for receiving the plasma, wherein the absorptive member is adapted to generate a capillary pressure so as to draw plasma from the separating member to the absorptive member. The first portion is fixed to the backing member in a manner to be removed without destroying the absorptive member. The absorptive member is fixed to the backing member in a manner to be removed without destroying the absorptive member.
摘要翻译：本发明涉及一种用于从血液样品分离血浆的装置，包括层叠结构，该层叠结构设置有包括具有用于施加或接收血液样本的第一表面的分离构件的第一部分，其中分离构件适于允许等离子体通过，但是抑制细胞通过，第二部分包括用于吸收等离子体的吸收部件，该第二部分具有与用于接收等离子体的分离部件接触的第二表面，其中吸收部件适于产生毛细管压力以将等离子体从分离构件吸入吸收构件。第一部分以不被破坏吸收构件的方式被移除而固定到背衬构件上。吸收构件以不会破坏吸收构件的方式被移除而固定到背衬构件上。

2. 发明申请

US20080210171A1 Milking parlor 审中-公开
标题翻译：挤奶厅
公开(公告)号：US20080210171A1
公开(公告)日：2008-09-04
申请号：US11904488
申请日：2007-09-27
申请人： Thomas Mader , Michael Heinrich , Otto Krone , Peter Kaever , Reinhard Frenser , Magnus Wiethoff , Matthias Ahrens , Klaus Fleck
发明人： Thomas Mader , Michael Heinrich , Otto Krone , Peter Kaever , Reinhard Frenser , Magnus Wiethoff , Matthias Ahrens , Klaus Fleck
IPC分类号： A01J5/00
CPC分类号： A01K1/12
摘要： A milking parlor, milking module, and a closing unit comprising at least two closing members to optionally release or close a corresponding number of openings in a milking parlor floor which serves as a standing area. The closing members are disposed to be rotatable about a rotational axis at least between a closed position and an open position, wherein the open position allows at least one animal-related treatment means to be guided through said opening. Said rotational axis is disposed in a central region between the closing members.
摘要翻译：挤奶室，挤奶模块和关闭单元，其包括至少两个关闭构件，以选择性地释放或关闭用作站立区域的挤奶厅底板中的相应数量的开口。关闭构件设置成可以至少在关闭位置和打开位置之间围绕旋转轴线旋转，其中打开位置允许至少一个动物相关治疗装置被引导通过所述开口。所述旋转轴线设置在封闭构件之间的中心区域中。

3. 发明授权

US5193285A Mechanical shape sensor and data recorder 失效
标题翻译：机械形状传感器和数据记录仪
公开(公告)号：US5193285A
公开(公告)日：1993-03-16
申请号：US739110
申请日：1991-08-01
申请人： Michael Heinrich , Eric-Jan Ginder
发明人： Michael Heinrich , Eric-Jan Ginder
IPC分类号： A47C31/12 , A61B5/107 , G01B5/207
CPC分类号： G01B5/207 , A47C31/126 , A61B5/1078
摘要： A mechanical shape sensor measures and provides a two-dimensional representation of the contour of a person's thighs and buttocks or the dorsal and lateral surfaces of a person's trunk for facilitating the fabrication of custom contoured seat cushions such as for use in a wheelchair. The mechanical shape sensor is integrated in a chair-like base capable of multiple adjustments to accommodate a range of dimensions and sizes of persons being measured. The mechanical shape sensor converts the three-dimensional contoured support surface of a person seated on an array of movable support elements into a two-dimensional format which is recorded on a data sheet in a form which is easily transmitted via telecommunications link to a central locatin for fabricating a custom contoured seat cushion. Each of the moveable support elements is coupled to a position marker in the data recorder. The position markers are disposed adjacent a pressure-sensitive data sheet inserted in the data recorder for engaging the data sheet and imprinting data points thereon when urged toward the data sheet by an impression-forming mechanism comprised of a pair of opposed rollers which are manually displaced in unison over the position markers. Each data point represents the depth of contour of the seat cushion at a given location with a person seated thereon. The data sheet is then removed from the data recorder for use in fabricating a custom contoured seat cushion.
摘要翻译：机械形状传感器测量和提供人的大腿和臀部或人的躯干的背侧和侧面的轮廓的二维表示，以便于制造用于轮椅的定制轮廓座垫。机械形状传感器集成在能够进行多次调整的椅子状基座中，以适应所测量人员的尺寸和尺寸。机械形状传感器将坐在可移动支撑元件阵列上的人的三维轮廓支撑表面转换成以通过电信链路容易地发送到中心位置的形式记录在数据表上的二维格式用于制造定制的轮廓座垫。每个可移动支撑元件耦合到数据记录器中的位置标记。位置标记物被设置在与数据记录器中插入的压敏数据表相邻，用于接合数据表并在通过由一对相对的辊组成的压印形成机构向数据表压印数据点时，压印数据点被手动移位在位置标记上一致。每个数据点表示坐在其上的人在给定位置处的座垫的轮廓深度。然后将数据表从数据记录器中取出，用于制造定制的轮廓座垫。

4. 发明授权

US5102195A Seating system 失效
标题翻译：座位系统
公开(公告)号：US5102195A
公开(公告)日：1992-04-07
申请号：US502867
申请日：1990-05-18
申请人： Peter Axelson , Michael Heinrich , Ann Lasko-Harvill , Michael W. Silverman
发明人： Peter Axelson , Michael Heinrich , Ann Lasko-Harvill , Michael W. Silverman
IPC分类号： A47C7/02 , A47C7/42 , A61G5/10 , A61G5/12
CPC分类号： A61G5/12 , A61G5/1043 , A61G5/1048 , A61G5/1067 , A61G5/1091 , A61G5/121 , Y10S297/04
摘要： A seating system includes seat and back internal support frames disposed within respective foam-filled seat and back cushions which each have an outer fabric cover. The back assembly is provided with a pair of quick-release clip locks, while the seat assembly includes a plurality of support hooks in combination with mounting brackets and locking mechanisms to facilitate quick mounting and removal of the seat from a support frame such as a wheelchair base. The seat and back assemblies are coupled together in a pivoting manner by means of a handle assembly which allows the seat to be compactly folded and easily carried when removed from a support base. The back inner support frame includes upper and lower support subassemblies pivotally coupled by means of a hinge joint which allows for extension of the lumbar region when the upper support subassembly is moved rearwardly to a reclined position. The seat and back support surfaces are contoured for user comfort and support while a lower, aft portion of the back cusion is provided with a plurality of corrugations to facilitate its flexure. The internal support frame includes telescoping members to allow the internal frame to fit a range of user sizes while the hinge joint in the lower portion of the back assembly may: (1) be locked in a fixed orientation; (2) incorporate forward and aft stops to limit pivoting displacement of the upper back; or (3) have a selected neutral position to which the upper back is biased.
摘要翻译：座椅系统包括设置在相应的充满泡沫的座椅和后靠垫中的座椅和后部内部支撑框架，每个椅子和后部衬垫均具有外部织物罩。后组件设置有一对快速释放夹锁，而座椅组件包括与安装支架和锁定机构组合的多个支撑钩，以便于座椅从诸如轮椅的支撑框架的快速安装和移除基础。座椅和后组件通过手柄组件以枢转的方式联接在一起，该手柄组件允许座椅被紧凑地折叠并且当从支撑座移除时容易携带。后部内部支撑框架包括通过铰链接头可枢转地联接的上部和下部支撑子组件，当铰链接头上部支撑组件向后移动到倾斜位置时允许延伸腰部区域。座椅和后支撑表面的轮廓是为了使用者的舒适和支撑，而后部凹陷的较低的后部设置有多个波纹以便于其弯曲。内部支撑框架包括伸缩构件，以允许内部框架适应一定范围的使用者尺寸，而后部组件的下部中的铰链接头可以：（1）以固定的方向被锁定; （2）包括前后挡块，以限制上背部的转动位移; 或（3）具有上背部被偏置的选定中性位置。

5. 发明授权

US07788336B2 Feedback system for visual content 有权
标题翻译：视觉内容反馈系统
公开(公告)号：US07788336B2
公开(公告)日：2010-08-31
申请号：US10880512
申请日：2004-07-01
申请人： Peter S. Ebert , Michael Heinrich , Ian J. Kimbell , Janaki P. Kumar , Steven Mann , Frederic E. Samson , Bernhard Schweizer , Zia Yusuf
发明人： Peter S. Ebert , Michael Heinrich , Ian J. Kimbell , Janaki P. Kumar , Steven Mann , Frederic E. Samson , Bernhard Schweizer , Zia Yusuf
IPC分类号： G06F15/16
CPC分类号： G06Q30/02
摘要： A feedback system for visual content is described that allows individual users to obtain feedback regarding selected visual content. A user of the system uploads any desired visual content, and associates the content with a feedback campaign having user-defined characteristics. The user also may associate feedback elements with the visual content, such as comments regarding the visual content or the type of feedback that is desired. The feedback system provides the visual content and feedback elements to selected other users, perhaps by sending a link to the other users via email. In this way, the receiving users may provide feedback regarding the visual content. In particular, the receiving users may generate a virtual note to be placed on a selected portion of the visual content, so as to provide comment specific to the selected portion. As a result, individual users are enabled to create and manage multiple feedback campaigns.
摘要翻译：描述了用于视觉内容的反馈系统，其允许个别用户获得关于所选视觉内容的反馈。系统的用户上传任何所需的视觉内容，并且将内容与具有用户定义特征的反馈活动相关联。用户还可以将反馈元素与视觉内容相关联，例如关于视觉内容的意见或期望的反馈的类型。反馈系统向选定的其他用户提供可视内容和反馈元素，可能通过电子邮件发送链接给其他用户。以这种方式，接收用户可以提供关于视觉内容的反馈。特别地，接收用户可以生成要放置在可视内容的所选部分上的虚拟音符，以便提供特定于所选部分的注释。因此，个人用户可以创建和管理多个反馈广告系列。

6. 发明申请

US20050192853A1 Feedback system for visual content 有权
标题翻译：视觉内容反馈系统
公开(公告)号：US20050192853A1
公开(公告)日：2005-09-01
申请号：US10880512
申请日：2004-07-01
申请人： Peter Ebert , Michael Heinrich , Ian Kimbell , Janaki Kumar , Steven Mann , Frederic Samson , Bernhard Schweizer , Zia Yusuf
发明人： Peter Ebert , Michael Heinrich , Ian Kimbell , Janaki Kumar , Steven Mann , Frederic Samson , Bernhard Schweizer , Zia Yusuf
IPC分类号： G06Q30/00 , G06F17/60
CPC分类号： G06Q30/02
摘要： A feedback system for visual content is described that allows individual users to obtain feedback regarding selected visual content. A user of the system uploads any desired visual content, and associates the content with a feedback campaign having user-defined characteristics. The user also may associate feedback elements with the visual content, such as comments regarding the visual content or the type of feedback that is desired. The feedback system provides the visual content and feedback elements to selected other users, perhaps by sending a link to the other users via email. In this way, the receiving users may provide feedback regarding the visual content. In particular, the receiving users may generate a virtual note to be placed on a selected portion of the visual content, so as to provide comment specific to the selected portion. As a result, individual users are enabled to create and manage multiple feedback campaigns.
摘要翻译：描述了用于视觉内容的反馈系统，其允许个别用户获得关于所选视觉内容的反馈。系统的用户上传任何所需的视觉内容，并且将内容与具有用户定义特征的反馈活动相关联。用户还可以将反馈元素与视觉内容相关联，例如关于视觉内容的意见或期望的反馈的类型。反馈系统向选定的其他用户提供可视内容和反馈元素，可能通过电子邮件发送链接给其他用户。以这种方式，接收用户可以提供关于视觉内容的反馈。特别地，接收用户可以生成要放置在可视内容的所选部分上的虚拟音符，以便提供特定于所选部分的注释。因此，个人用户可以创建和管理多个反馈广告系列。

7. 发明授权

US4998354A Mechanical shape sensor 失效
标题翻译：机械形状传感器
公开(公告)号：US4998354A
公开(公告)日：1991-03-12
申请号：US540842
申请日：1990-06-20
申请人： Michael W. Silverman , Michael Heinrich , Clifford E. Brubaker , Colin A. McLaurin
发明人： Michael W. Silverman , Michael Heinrich , Clifford E. Brubaker , Colin A. McLaurin
IPC分类号： G01B5/207
CPC分类号： G01B5/207
摘要： Apparatus for measuring and providing a two-dimensional representation of the contour of a person's thighs and buttocks or the dorsal and lateral surfaces of a person's trunk facilitates the fabrication of custom contoured seat cushions such as for use by wheelchair users. The apparatus includes a frame having a rectangular matrix of compressible, resilient support elements with a generally flat upper surface. Attached to the upper surface of each support element is one end of a flexible, incompressible cable which is inserted through a conduit with a 90.degree. bend for directing the cable toward and beyond a side of the frame. Second end portions of the cable and conduit combinations are in parallel, planar alignment. The cable is free to move within and along the length of the conduit such that downward displacement of the upper surface of a support element and first end of a cable coupled thereto causes the cable's second end to be moved outward from the frame. By arranging the second end portions of the cables in a cyclic manner in accordance with the number of support elements in a given row within the matrix, the three-dimensional contoured support surface of a person sitting on the array of support elements is presented in two dimensions in a format which is easily recorded and reproduced for fabricating a custom contoured seat cushion.
摘要翻译：用于测量和提供人的大腿和臀部或人的躯干背面和侧面的轮廓的二维表示的装置有利于制造定制轮廓座垫，例如轮椅使用者使用。该装置包括具有矩形矩阵矩阵的框架，该矩形矩阵具有大致平坦的上表面的可压缩弹性支撑元件。每个支撑元件的上表面的一端是柔性不可压缩的电缆的一端，该电缆插入通过90°弯曲的导管，用于引导电缆朝向和超出框架的一侧。电缆和导管组合的第二端部是平行的平面对准。电缆可自由地在管道的长度内移动，使得支撑元件的上表面和耦合到其的电缆的第一端的向下移位导致电缆的第二端从框架向外移动。通过根据矩阵内的给定行中的支撑元件的数量以循环方式布置电缆的第二端部，坐在支撑元件阵列上的人的三维轮廓支撑表面呈现为两个尺寸可以容易地记录和再现，用于制造定制的轮廓座垫。

8. 发明申请

US20200147466A1 PORTABLE GAME RECEPTACLE TARGET FOR RECEIVING GAME PIECES 审中-公开
公开(公告)号：US20200147466A1
公开(公告)日：2020-05-14
申请号：US16191246
申请日：2018-11-14
申请人： Michael Heinrich
发明人： Michael Heinrich
IPC分类号： A63B67/06 , A63F7/00
摘要： People love fun fast paced family friendly party games having elements of skill and luck allowing everyone to get in on the fun. Fast paced game play can be a more hygienic alternative to beer pong with the receptacle target being portable, lightweight, durable, compactly storable, placeable for instance onto a table or a truck tailgate. Embodiments can be used as amusement games with players stacking game pieces on or tossing game pieces towards a receptacle target. Innovative elegant designs brings out the natural beauty of wood or other stylistic materials in a fun functional manner.

9. 发明授权

US06990923B2 Milker unit detacher for rotary milking parlor 失效
标题翻译：旋转挤奶厅的Milker单位拆卸机
公开(公告)号：US06990923B2
公开(公告)日：2006-01-31
申请号：US10929889
申请日：2004-08-30
申请人： Patrick M. Hein , Jeffrey S. Hanson , Michael Heinrich , Frank Hoelscher , Larry G. Larson , Peter Kaever , Karsten Schonrock
发明人： Patrick M. Hein , Jeffrey S. Hanson , Michael Heinrich , Frank Hoelscher , Larry G. Larson , Peter Kaever , Karsten Schonrock
IPC分类号： A01J5/00
CPC分类号： A01J5/017 , A01K1/123
摘要： A rotary milking parlor milker detacher having a pivoting support arm and retracting chain arrangement that is synchronized with a rotating platform position to move the detacher between a storage position, a presentation position, and a milking position to protect the detacher from damage and provide a superior ergonomic design that reduces operator fatigue and turnover.
摘要翻译：一种具有枢转支撑臂和回缩链条装置的旋转挤奶室挤奶器分离器，其与旋转平台位置同步，以在存储位置，呈现位置和挤奶位置之间移动分离器，以保护分离器免受损坏并提供优越性符合人体工学的设计，减少操作员的疲劳和更换。

10. 发明申请

US20050100891A1 Gene expression profile for KSHV infection and methods for treating same 审中-公开
标题翻译： KSHV感染的基因表达谱及其治疗方法
公开(公告)号：US20050100891A1
公开(公告)日：2005-05-12
申请号：US11019987
申请日：2004-12-23
申请人： Mattias Luukkonen , Ashlee Moses , Klaus Frueh , Jay Nelson , Yolanda Bell , Michael Heinrich , Kenneth Simmen
发明人： Mattias Luukkonen , Ashlee Moses , Klaus Frueh , Jay Nelson , Yolanda Bell , Michael Heinrich , Kenneth Simmen
IPC分类号： G01N33/53 , A61K31/00 , A61K31/07 , A61K31/337 , A61K31/704 , A61K38/21 , A61K45/00 , A61K45/06 , A61P31/22 , C12M1/00 , C12N15/09 , C12Q1/02 , C12Q1/68 , C12Q1/6837 , C12Q1/6883 , G01N21/77 , G01N21/78 , G01N33/58 , G01N37/00 , G06Q50/22 , C12Q1/70 , C12M1/34 , A61K38/16
CPC分类号： C12Q1/6883 , A61K31/00 , A61K31/337 , A61K31/704 , A61K38/212 , A61K45/06 , C12Q1/6837 , C12Q2600/158 , G06Q50/22 , Y02A90/22 , A61K2300/00
摘要： The present invention utilizes nucleic acid microarray technology to identify changes in the host endothelial cell transcription pattern that occurs during the latent and lytic phase of the KSHV life cycle. The production or activity of some genes up regulated during the lytic cycle were subsequently inhibited, and two such targets were shown to have a role in expression of late viral genes. Using this combined approach we have identified cellular pathways previously unknown to be important for KSHV infection, and present evidence for the efficiency of the novel antiviral approaches thus discovered. In addition, the present invention identifies a wide variety of endothelial cells genes and pathways that are involved in a variety of endothelial cell-mediated activity, including angiogenesis and transformation.
摘要翻译：本发明利用核酸微阵列技术鉴定在KSHV生命周期的潜伏期和裂解期期间发生的宿主内皮细胞转录模式的变化。随后抑制溶解循环中上调的一些基因的产生或活性，并且显示出两个这样的靶点在晚期病毒基因的表达中起作用。使用这种组合方法，我们已经确定以前未知对KSHV感染重要的细胞途径，并提供了因此发现的新型抗病毒方法的效率的证据。此外，本发明鉴定参与多种内皮细胞介导的活性的多种内皮细胞基因和途径，包括血管生成和转化。

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