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1. 发明授权

US08895771B2 Methods of making organic compounds by metathesis and hydrocyanation 有权
标题翻译：通过复分解和氢化法制备有机化合物的方法
公开(公告)号：US08895771B2
公开(公告)日：2014-11-25
申请号：US12422109
申请日：2009-04-10
申请人： Timothy W. Abraham , Hiroki Kaido , Choon Woo Lee , Richard L. Pederson , Yann Schrodi , Michael John Tupy , Alexandre A. Pletnev
发明人： Timothy W. Abraham , Hiroki Kaido , Choon Woo Lee , Richard L. Pederson , Yann Schrodi , Michael John Tupy , Alexandre A. Pletnev
IPC分类号： C07C253/10 , B01J31/22 , C07C6/04 , C11C3/04 , C07C45/44 , C07C227/10 , C07C51/08 , C07C51/353 , C07C67/333
CPC分类号： C07C253/10 , B01J31/2265 , B01J31/2278 , B01J2231/54 , B01J2531/821 , C07C6/04 , C07C45/44 , C07C51/08 , C07C51/353 , C07C67/08 , C07C67/31 , C07C67/313 , C07C67/333 , C07C67/347 , C07C227/04 , C07C227/10 , C07C2531/24 , C11C3/04 , Y02P20/127 , C07C57/03 , C07C57/42 , C07C59/01 , C07C59/325 , C07C69/533 , C07C229/08 , C07C255/19
摘要： The invention is directed to methods of making organic compounds by metathesis and hydrocyanation. The method of the invention may be used, for example, to make industrial important organic compounds such as diacids, diesters, acid-amines, acid-alcohols, acid-nitriles, ester-amines, ester-alcohols, and ester-nitriles.
摘要翻译：本发明涉及通过复分解和氢氰化制备有机化合物的方法。本发明的方法可用于例如制备工业上重要的有机化合物如二酸，二酯，酸 - 胺，酸 - 醇，酸 - 腈，酯 - 胺，酯 - 醇和酯 - 腈。

2. 发明申请

US20090259065A1 METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS AND HYDROCYANATION 有权
标题翻译：通过元素和水解制备有机化合物的方法
公开(公告)号：US20090259065A1
公开(公告)日：2009-10-15
申请号：US12422109
申请日：2009-04-10
申请人： Timothy W. Abraham , Hiroki Kaido , Choon Woo Lee , Richard L. Pederson , Yann Schrodi , Michael John Tupy , Alexandre A. Pletnev
发明人： Timothy W. Abraham , Hiroki Kaido , Choon Woo Lee , Richard L. Pederson , Yann Schrodi , Michael John Tupy , Alexandre A. Pletnev
IPC分类号： C07C253/10 , C07C229/12 , C07C69/67 , C07C69/675 , C07C211/03 , C07C59/01 , C07C55/02
CPC分类号： C07C253/10 , B01J31/2265 , B01J31/2278 , B01J2231/54 , B01J2531/821 , C07C6/04 , C07C45/44 , C07C51/08 , C07C51/353 , C07C67/08 , C07C67/31 , C07C67/313 , C07C67/333 , C07C67/347 , C07C227/04 , C07C227/10 , C07C2531/24 , C11C3/04 , Y02P20/127 , C07C57/03 , C07C57/42 , C07C59/01 , C07C59/325 , C07C69/533 , C07C229/08 , C07C255/19
摘要： The invention is directed to methods of making organic compounds by metathesis and hydrocyanation. The method of the invention may be used, for example, to make industrial important organic compounds such as diacids, diesters, acid-amines, acid-alcohols, acid-nitriles, ester-amines, ester-alcohols, and ester-nitriles.
摘要翻译：本发明涉及通过复分解和氢氰化制备有机化合物的方法。本发明的方法可用于例如制备工业上重要的有机化合物如二酸，二酯，酸 - 胺，酸 - 醇，酸 - 腈，酯 - 胺，酯 - 醇和酯 - 腈。

3. 发明申请

US20090264672A1 METHODS OF MAKING ORGANIC COMPOUNDS BY METATHESIS 有权
标题翻译：通过METATHESIS制备有机化合物的方法
公开(公告)号：US20090264672A1
公开(公告)日：2009-10-22
申请号：US12422096
申请日：2009-04-10
申请人： Timothy W. Abraham , Hiroki Kaido , Choon Woo Lee , Richard L. Pederson , Yann Schrodi , Michael John Tupy
发明人： Timothy W. Abraham , Hiroki Kaido , Choon Woo Lee , Richard L. Pederson , Yann Schrodi , Michael John Tupy
IPC分类号： C07C69/52 , C07C57/13
CPC分类号： C07C67/475 , B01J31/2265 , B01J31/2278 , B01J2231/543 , B01J2531/821 , C07C6/04 , C07C67/02 , C07C67/303 , C07C67/307 , C07C67/31 , C07C67/333 , C07C2531/22 , C07C2531/24 , C07F7/1884 , C07C11/02 , C07C69/65 , C07C69/734 , C07C69/533 , C07C69/593 , C07C69/73
摘要： Described are methods of making organic compounds by metathesis chemistry. The methods of the invention are particularly useful for making industrially-important organic compounds beginning with starting compositions derived from renewable feedstocks, such as natural oils. The methods make use of a cross-metathesis step with an olefin compound to produce functionalized alkene intermediates having a pre-determined double bond position. Once isolated, the functionalized alkene intermediate can be self-metathesized or cross-metathesized (e.g., with a second functionalized alkene) to produce the desired organic compound or a precursor thereto. The method may be used to make bifunctional organic compounds, such as diacids, diesters, dicarboxylate salts, acid/esters, acid/amines, acid/alcohols, acid/aldehydes, acid/ketones, acid/halides, acid/nitriles, ester/amines, ester/alcohols, ester/aldehydes, ester/ketones, ester/halides, ester/nitriles, and the like.
摘要翻译：描述的是通过复分解化学制备有机化合物的方法。本发明的方法特别可用于制备工业上重要的有机化合物，起始于可再生原料如天然油的组合物。该方法利用与烯烃化合物的交叉复分解步骤来制备具有预定双键位置的官能化烯烃中间体。一旦分离，官能化的烯烃中间体可以是自我化的或交叉的（例如用第二官能化的烯烃）产生所需的有机化合物或其前体。该方法可用于制备双官能有机化合物，例如二酸，二酯，二羧酸盐，酸/酯，酸/胺，酸/醇，酸/醛，酸/酮，酸/卤化物，酸/腈，酯/ 胺，酯/醇，酯/醛，酯/酮，酯/卤化物，酯/腈等。

4. 发明授权

US09120742B2 Methods of making organic compounds by metathesis 有权
标题翻译：通过复分解制备有机化合物的方法
公开(公告)号：US09120742B2
公开(公告)日：2015-09-01
申请号：US12422096
申请日：2009-04-10
申请人： Timothy W. Abraham , Hiroki Kaido , Choon Woo Lee , Richard L. Pederson , Yann Schrodi , Michael John Tupy
发明人： Timothy W. Abraham , Hiroki Kaido , Choon Woo Lee , Richard L. Pederson , Yann Schrodi , Michael John Tupy
IPC分类号： C07C69/52 , C07C57/13 , C07C67/333 , B01J31/22 , C07C6/04 , C07C67/307 , C07C67/31 , C07C67/475
CPC分类号： C07C67/475 , B01J31/2265 , B01J31/2278 , B01J2231/543 , B01J2531/821 , C07C6/04 , C07C67/02 , C07C67/303 , C07C67/307 , C07C67/31 , C07C67/333 , C07C2531/22 , C07C2531/24 , C07F7/1884 , C07C11/02 , C07C69/65 , C07C69/734 , C07C69/533 , C07C69/593 , C07C69/73
摘要： Described are methods of making organic compounds by metathesis chemistry. The methods of the invention are particularly useful for making industrially-important organic compounds beginning with starting compositions derived from renewable feedstocks, such as natural oils. The methods make use of a cross-metathesis step with an olefin compound to produce functionalized alkene intermediates having a pre-determined double bond position. Once isolated, the functionalized alkene intermediate can be self-metathesized or cross-metathesized (e.g., with a second functionalized alkene) to produce the desired organic compound or a precursor thereto. The method may be used to make bifunctional organic compounds, such as diacids, diesters, dicarboxylate salts, acid/esters, acid/amines, acid/alcohols, acid/aldehydes, acid/ketones, acid/halides, acid/nitriles, ester/amines, ester/alcohols, ester/aldehydes, ester/ketones, ester/halides, ester/nitriles, and the like.
摘要翻译：描述的是通过复分解化学制备有机化合物的方法。本发明的方法特别可用于制备工业上重要的有机化合物，起始于可再生原料如天然油的组合物。该方法利用与烯烃化合物的交叉复分解步骤来制备具有预定双键位置的官能化烯烃中间体。一旦分离，官能化的烯烃中间体可以是自我化的或交叉的（例如用第二官能化的烯烃）产生所需的有机化合物或其前体。酸/酸，酸/酮，酸/卤化物，酸/腈，酯/酯，酸/ 胺，酯/醇，酯/醛，酯/酮，酯/卤化物，酯/腈等。

5. 发明授权

US07507854B2 Impurity reduction in Olefin metathesis reactions 失效
标题翻译：烯烃复分解反应的杂质减少
公开(公告)号：US07507854B2
公开(公告)日：2009-03-24
申请号：US10924743
申请日：2004-08-23
申请人： Choon Woo Lee , Soon Hyeok Hong , Daniel P. Sanders , Robert H. Grubbs , Richard L. Pederson
发明人： Choon Woo Lee , Soon Hyeok Hong , Daniel P. Sanders , Robert H. Grubbs , Richard L. Pederson
IPC分类号： C07C69/52
CPC分类号： C07D303/04 , C07C6/04 , C07C67/293 , C07C2531/24 , C07D207/20 , C07C69/007 , C07C69/145 , C07C69/533
摘要： The present invention relates to the use of isomerization inhibitors in olefin metathesis reactions. The inhibitors are low molecular weight organic acids such as formic acid, acetic acid, benzoic acid, and the like.
摘要翻译：本发明涉及异构化抑制剂在烯烃复分解反应中的用途。抑制剂是低分子量有机酸，例如甲酸，乙酸，苯甲酸等。

6. 发明授权

US09249360B2 Compositions derived from metathesized natural oils and amines and methods of making 有权
标题翻译：衍生自复分解天然油和胺的组合物及其制备方法
公开(公告)号：US09249360B2
公开(公告)日：2016-02-02
申请号：US13176851
申请日：2011-07-06
申请人： Monika Mujkic , Deidra Cade , Choon Woo Lee , Michael S. Starch , Brian J. Swanton
发明人： Monika Mujkic , Deidra Cade , Choon Woo Lee , Michael S. Starch , Brian J. Swanton
IPC分类号： A61K8/92 , C10G3/00 , A61Q19/00 , C08L91/06
CPC分类号： A61K8/922 , A61K2800/10 , A61Q1/06 , A61Q5/00 , A61Q17/04 , A61Q19/00 , A61Q19/007 , C08L91/06 , C10G3/00 , C10G2300/1014 , C10G2300/1018 , C10G2300/20 , C10G2300/202 , Y02P30/20
摘要： Wax compositions derived from metathesized natural oils and amines and methods of making wax compositions from metathesized natural oils and amines are provided. The wax compositions comprise amidated metathesized natural oils formed from a metathesized natural oil and at least one amine. The methods comprise providing an amine and providing a metathesized natural oil. The methods further comprise mixing the amine and the metathesized natural oil in the presence of a basic catalyst or heat, causing a reaction between the amine and metathesized natural oil, therein forming the amidated metathesized natural oil.
摘要翻译：提供衍生自复分解天然油和胺的蜡组合物以及由复分解天然油和胺制备蜡组合物的方法。蜡组合物包含由复分解的天然油和至少一种胺形成的酰胺化的复分解的天然油。所述方法包括提供胺并提供复分解的天然油。所述方法还包括在碱性催化剂或热的存在下混合胺和复分解的天然油，引起胺和复分解天然油之间的反应，形成酰胺化的复分解天然油。

7. 发明申请

US20120010303A1 WAXES DERIVED FROM METATHESIZED NATURAL OILS AND AMINES AND METHODS OF MAKING 有权
标题翻译：衍生自自然天然油和氨基酸的盐和制备方法
公开(公告)号：US20120010303A1
公开(公告)日：2012-01-12
申请号：US13176851
申请日：2011-07-06
申请人： Monika Mujkic , Deidra Cade , Choon Woo Lee , Michael S. Starch , Brian J. Swanton
发明人： Monika Mujkic , Deidra Cade , Choon Woo Lee , Michael S. Starch , Brian J. Swanton
IPC分类号： A61K8/92
CPC分类号： A61K8/922 , A61K2800/10 , A61Q1/06 , A61Q5/00 , A61Q17/04 , A61Q19/00 , A61Q19/007 , C08L91/06 , C10G3/00 , C10G2300/1014 , C10G2300/1018 , C10G2300/20 , C10G2300/202 , Y02P30/20
摘要： Wax compositions derived from metathesized natural oils and amines and methods of making wax compositions from metathesized natural oils and amines are provided. The wax compositions comprise amidated metathesized natural oils formed from a metathesized natural oil and at least one amine. The methods comprise providing an amine and providing a metathesized natural oil. The methods further comprise mixing the amine and the metathesized natural oil in the presence of a basic catalyst or heat, causing a reaction between the amine and metathesized natural oil, therein forming the amidated metathesized natural oil.
摘要翻译：提供衍生自复分解天然油和胺的蜡组合物以及由复分解天然油和胺制备蜡组合物的方法。蜡组合物包含由复分解的天然油和至少一种胺形成的酰胺化的复分解的天然油。所述方法包括提供胺并提供复分解的天然油。所述方法还包括在碱性催化剂或热的存在下混合胺和复分解的天然油，引起胺和复分解天然油之间的反应，形成酰胺化的复分解天然油。

8. 发明授权

US07387204B2 Pull-up tray container 有权
标题翻译：上拉托盘容器
公开(公告)号：US07387204B2
公开(公告)日：2008-06-17
申请号：US10901535
申请日：2004-07-29
申请人： Choon Woo Lee
发明人： Choon Woo Lee
IPC分类号： B65D69/00
CPC分类号： A45C11/008 , B65D83/005 , Y10S206/804 , Y10S206/817
摘要： A cosmetic brush container has a cylindrical sidewall, a closed bottom, and an open top. A tray is carried within the container for axial movement relative to a longitudinal axis of the container from a lower storage position. A lid releasably fits over the top of the container. A rod extends between the tray and the lid. Brushes are carried in the container, with lower ends supported on the tray and bristles supported by the sidewall of the container. Lifting the lid causes the tray to move upward and the bristles of the brushes to move above the top of the container for access by a user.
摘要翻译：化妆刷容器具有圆柱形侧壁，封闭底部和敞开的顶部。在容器内承载托盘，用于相对于容器的纵向轴线从下部存储位置轴向移动。盖可拆卸地装配在容器的顶部上。杆在托盘和盖子之间延伸。刷子装在容器中，下端支撑在托盘上，刷毛由容器的侧壁支撑。提起盖子使得托盘向上移动并且刷子的刷毛在容器的顶部上方移动以供用户访问。

9. 发明授权

US08512722B2 Antimicrobial materials 有权
标题翻译：抗菌材料
公开(公告)号：US08512722B2
公开(公告)日：2013-08-20
申请号：US12842593
申请日：2010-07-23
申请人： Choon Woo Lee , Robert H. Grubbs , Mark Humayun
发明人： Choon Woo Lee , Robert H. Grubbs , Mark Humayun
IPC分类号： A01N25/10
CPC分类号： C09D5/14 , A01N33/12 , C08G73/0206 , C08G73/0226 , C09D5/1637 , C09D179/02 , D06M16/00 , Y10T428/31721 , Y10T428/31725 , A01N25/34 , A01N2300/00
摘要： The disclosure provides methods and materials suitable for preparing coating layers on substrates. The coatings comprise quaternary amine groups and therefore impart anti-bacterial properties to the substrate. In one embodiment, for example, there is provided a quaternary amine-containing polymeric coating comprising propylene and ethylene repeat units.
摘要翻译：本公开提供了适合于在基底上制备涂层的方法和材料。涂层包含季胺基，因此赋予基底抗菌性能。在一个实施方案中，例如，提供了包含丙烯和乙烯重复单元的含季铵的聚合物涂层。

10. 发明授权

US07034096B2 Ring-expansion of cyclic olefins metathesis reactions with an acyclic diene 有权
标题翻译：环烯烃与无环二烯的复分解反应的环扩展
公开(公告)号：US07034096B2
公开(公告)日：2006-04-25
申请号：US10371196
申请日：2003-02-19
申请人： Tae-Lim Choi , Choon Woo Lee , Hyunjin M. Kim , Robert H. Grubbs
发明人： Tae-Lim Choi , Choon Woo Lee , Hyunjin M. Kim , Robert H. Grubbs
IPC分类号： C08F4/44 , B01J31/38
CPC分类号： C07F7/1892 , B01J31/2265 , C08G61/08
摘要： This invention relates generally to synthetic procedures that include the step of ring-opening metathesis of cyclic olefins and reaction with an acyclic diene co-reactant to produce olefin macrocycles by ring expansion, or alternatively. The ring expansion of the cyclic olefin is provided by three types of sequential olefin metathesis (ring-opening, cross, and ring-closing olefin metathesis). More particularly, the invention pertains to synthesis of olefin macrocycles via olefin metathesis reactions using a Group 8 transition metal complex as the metathesis catalyst. Macrocycles provided herein have a variety of uses in the pharmaceutical, biomedical, organic synthesis and chemical industries, such as the production of crown ethers that are useful as metal complexing species.
摘要翻译：本发明一般涉及合成方法，其包括环烯烃的开环复分解步骤和与无环二烯共反应物反应以通过环扩展产生烯烃大环化合物的步骤。环烯烃的环扩展由三种顺序烯烃复分解（开环，交叉和闭环烯烃复分解）提供。更具体地，本发明涉及通过使用第8族过渡金属络合物作为复分解催化剂的烯烃复分解反应合成烯烃大环化合物。本文提供的大环在药物，生物医学，有机合成和化学工业中具有多种用途，例如可用作金属络合物质的冠醚的生产。

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