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1. 发明授权

US08540664B2 Probablistic pharmacokinetic and pharmacodynamic modeling 有权
公开(公告)号：US08540664B2
公开(公告)日：2013-09-24
申请号：US13260073
申请日：2010-03-24
申请人： Timothy Robertson , Yashar Behzadi
发明人： Timothy Robertson , Yashar Behzadi
IPC分类号： A61M5/168 , G08B1/08
CPC分类号： A61M5/1723 , G06F19/00 , G06F19/3456
摘要： The subject matter disclosed herein provides a response to a dose of a substance and/or controls the administration of the dose. In one aspect, there is provided a system. The system may include a processor and at least one memory configured to provide a response determinator. The response determinator may receive therapeutic and wellness data. Moreover, the response determinator may determine a response based on the received therapeutic and wellness data. The response may represent a reaction to a substance integrated with an ingestible event marker. The determined response may be provided to, for example, a therapy controller. Related systems, methods, and articles of manufacture are also described.

2. 发明申请

US20110009715A1 INGESTIBLE EVENT MARKER DATA FRAMEWORK 审中-公开
标题翻译：不可思议的事件标记数据框架
公开(公告)号：US20110009715A1
公开(公告)日：2011-01-13
申请号：US12522249
申请日：2009-07-02
申请人： David O' Reilly , Erika Karplus , Andrew Thompson , George Savage , Mark Zdeblick , Timothy Robertson , Lawrence Arne , Yashar Behzadi , Gregory Moon , Patrick Beaulieu
发明人： David O' Reilly , Erika Karplus , Andrew Thompson , George Savage , Mark Zdeblick , Timothy Robertson , Lawrence Arne , Yashar Behzadi , Gregory Moon , Patrick Beaulieu
IPC分类号： A61B5/07
CPC分类号： A61B5/07 , A61B5/0022 , A61B5/021 , G06F19/3418 , G06F19/3456
摘要： The ingestible event marker data framework provides a uniform, comprehensive framework to enable various functions and utilities related to ingestible event marker data (IEM data). The functions and utilities include data and/or information having an aspect of data derived from, collected by, aggregated by, or otherwise associated with, an ingestion event.
摘要翻译：可摄入事件标记数据框架提供统一的全面框架，以实现与可摄取事件标记数据（IEM数据）相关的各种功能和实用程序。功能和实用程序包括具有从摄取事件导出，收集，聚合或以其他方式与之相关的数据的方面的数据和/或信息。

3. 发明申请

US20100280366A1 CONTINUOUS FIELD TOMOGRAPHY SYSTEMS AND METHODS OF USING THE SAME 审中-公开
标题翻译：连续的田间计量系统及其使用方法
公开(公告)号：US20100280366A1
公开(公告)日：2010-11-04
申请号：US12522537
申请日：2009-05-12
申请人： Lawrence Arne , Orlando Banos , Yashar Behzadi , Olivier Colliou , Benedict Costello , Robert Leichner , Gregory Moon , Timothy Robertson , George Savage , Todd Thompson , Mark Zdeblick
发明人： Lawrence Arne , Orlando Banos , Yashar Behzadi , Olivier Colliou , Benedict Costello , Robert Leichner , Gregory Moon , Timothy Robertson , George Savage , Todd Thompson , Mark Zdeblick
IPC分类号： A61B5/05
CPC分类号： A61B5/046 , A61B5/0006 , A61B5/0031 , A61B5/0422 , A61B5/0536 , A61B5/0538 , A61B5/4519 , A61B5/743 , A61B5/7435 , A61B6/503 , A61B8/0883
摘要： Continuous field tomography systems are provided. Aspects of systems include a data aggregating module configured to receive both continuous field tomography data and non-continuous field physiological data and produce an aggregated data product from these disparate types of data. Also provided are methods of using systems of the invention in a variety of different applications, including diagnostic and therapeutic applications. The systems and methods of the invention find use in a variety of different applications, such as cardiac related applications.
摘要翻译：提供连续场断层摄影系统。系统的方面包括数据聚合模块，其配置为接收连续场断层摄影数据和非连续场生理数据，并从这些不同类型的数据产生聚合数据产物。还提供了在各种不同应用中使用本发明的系统的方法，包括诊断和治疗应用。本发明的系统和方法可用于各种不同的应用，例如心脏相关应用。

4. 发明授权

US08545436B2 Body-associated receiver and method 有权
公开(公告)号：US08545436B2
公开(公告)日：2013-10-01
申请号：US13336956
申请日：2011-12-23
申请人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
发明人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
IPC分类号： A61M5/168
CPC分类号： A61M5/1723 , A61B5/0006 , A61B5/0028 , A61B5/02055 , A61B5/0404 , A61B5/04085 , A61B5/0428 , A61B5/053 , A61B5/11 , A61B5/1112 , A61B5/145 , A61B5/14532 , A61B5/4094 , A61B2560/0209 , A61B2560/0412 , A61B2560/0468 , A61B2562/0219 , A61M5/1452 , A61M5/172 , G06F19/34 , G06F19/3418 , H04B13/005
摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.

5. 发明申请

US20120022443A1 Probablistic Pharmacokinetic and Pharmacodynamic Modeling 有权
标题翻译：概率药代动力学和药效学建模
公开(公告)号：US20120022443A1
公开(公告)日：2012-01-26
申请号：US13260073
申请日：2010-03-24
申请人： Timothy Robertson , Yashar Behzadi
发明人： Timothy Robertson , Yashar Behzadi
IPC分类号： A61M5/168 , G06N5/00
CPC分类号： A61M5/1723 , G06F19/00 , G06F19/3456
摘要： The subject matter disclosed herein provides a response to a dose of a substance and/or controls the administration of the dose. In one aspect, there is provided a system. The system may include a processor and at least one memory configured to provide a response determinator. The response determinator may receive therapeutic and wellness data. Moreover, the response determinator may determine a response based on the received therapeutic and wellness data. The response may represent a reaction to a substance integrated with an ingestible event marker. The determined response may be provided to, for example, a therapy controller. Related systems, methods, and articles of manufacture are also described.
摘要翻译：本文公开的主题提供对物质的剂量的响应和/或控制剂量的施用。在一个方面，提供了一种系统。该系统可以包括处理器和配置成提供响应确定器的至少一个存储器。响应确定器可以接收治疗和健康数据。此外，响应确定器可以基于接收到的治疗和健康数据来确定响应。该反应可能代表与可摄入事件标记物结合的物质的反应。所确定的响应可以被提供给例如治疗控制器。还描述了相关系统，方法和制品。

6. 发明授权

US09235683B2 Apparatus, system, and method for managing adherence to a regimen 有权
标题翻译：用于管理对方案的依从性的装置，系统和方法
公开(公告)号：US09235683B2
公开(公告)日：2016-01-12
申请号：US13292440
申请日：2011-11-09
申请人： Timothy Robertson , Gregory Moon , Arna Ionescu , Yashar Behzadi , David O'Reilly , Aaron Filner , Erika Karplus , Danielle Cojuangco , Sara Burgess
发明人： Timothy Robertson , Gregory Moon , Arna Ionescu , Yashar Behzadi , David O'Reilly , Aaron Filner , Erika Karplus , Danielle Cojuangco , Sara Burgess
IPC分类号： G06F3/048 , G06F19/00
CPC分类号： G06F19/3418 , G06F19/00 , G06F19/3456 , G16H15/00
摘要： A method of managing adherence to a regimen in a subscription based computer implemented healthcare information environment. The method includes receiving at a mobile device information from a receiver that a dose was ingested by a living subject. The mobile device comprises a processor, a memory and a display coupled to the processor. The method provides wirelessly communicating the information over a wireless network to a backend computer processing system and receiving from the computer at the backend processing system a personal information stream characterizing behavior of the living subject based on the received information over a predetermined period. An apparatus includes an adherence package including a foldable sheet, at least one of blister pack coupled to the foldable sheet, at least one ingestible device associated with a dose, and a perforation provided on the foldable sheet to enable removal of the at the least one blister pack.
摘要翻译：一种在基于订阅的计算机实施的医疗保健信息环境中管理对方案的依从性的方法。该方法包括在移动设备处接收来自接收者的信息，即由活体受试者摄入的剂量。移动设备包括处理器，存储器和耦合到处理器的显示器。该方法通过无线网络将信息无线地传送到后端计算机处理系统，并且在后端处理系统中从计算机接收基于所接收的信息在预定时段内表征活体的行为的个人信息流。一种装置包括粘附包装，其包括可折叠片材，耦合到可折叠片材的至少一个泡罩包装物，与剂量相关联的至少一个可摄取装置，以及设置在可折叠片材上的穿孔，以能够移除至少一个吸塑包装。

7. 发明授权

US08480616B2 Probablistic pharmacokinetic and pharmacodynamic modeling 有权
公开(公告)号：US08480616B2
公开(公告)日：2013-07-09
申请号：US13260073
申请日：2010-03-24
申请人： Timothy Robertson , Yashar Behzadi
发明人： Timothy Robertson , Yashar Behzadi
IPC分类号： A61M5/168 , G08B1/08
摘要： The subject matter disclosed herein provides a response to a dose of a substance and/or controls the administration of the dose. In one aspect, there is provided a system. The system may include a processor and at least one memory configured to provide a response determinator. The response determinator may receive therapeutic and wellness data. Moreover, the response determinator may determine a response based on the received therapeutic and wellness data. The response may represent a reaction to a substance integrated with an ingestible event marker. The determined response may be provided to, for example, a therapy controller. Related systems, methods, and articles of manufacture are also described.

8. 发明申请

US20120101430A1 Body-Associated Receiver and Method 有权
标题翻译：身体相关接收者和方法
公开(公告)号：US20120101430A1
公开(公告)日：2012-04-26
申请号：US13336956
申请日：2011-12-23
申请人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
发明人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
IPC分类号： A61M5/168 , H04B5/00
CPC分类号： A61M5/1723 , A61B5/0006 , A61B5/0028 , A61B5/02055 , A61B5/0404 , A61B5/04085 , A61B5/0428 , A61B5/053 , A61B5/11 , A61B5/1112 , A61B5/145 , A61B5/14532 , A61B5/4094 , A61B2560/0209 , A61B2560/0412 , A61B2560/0468 , A61B2562/0219 , A61M5/1452 , A61M5/172 , G06F19/34 , G06F19/3418 , H04B13/005
摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.
摘要翻译：提供可能是外部或可植入的接收器。本发明的接收机的方面包括存在一个或多个：高功率低功率模块; 中介模块; 电源模块，被配置为激活和去激活一个或多个电源给高功率处理块; 连接主站和从站的串行外设接口总线; 和多用途连接器。本发明的接收机可以被配置为接收电传送的信号。还提供了包括接收器的系统，以及使用它们的方法。另外公开了使用接收器来配合给药系统的系统和方法。

9. 发明授权

US08114021B2 Body-associated receiver and method 有权
标题翻译：身体相关的接收器和方法
公开(公告)号：US08114021B2
公开(公告)日：2012-02-14
申请号：US12673326
申请日：2009-12-15
申请人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
发明人： Timothy Robertson , Fataneh Omidvar , Yashar Behzadi , Lawrence Arne , Kenneth Rowberry , James Hutchison , Robert Leichner , George Savage , Andrew Thompson , Mark Zdeblick , Marc Kreidler , Hooman Hafezi , Robert Duck
IPC分类号： A61M5/20 , A61B5/00
CPC分类号： A61M5/1723 , A61B5/0006 , A61B5/0028 , A61B5/02055 , A61B5/0404 , A61B5/04085 , A61B5/0428 , A61B5/053 , A61B5/11 , A61B5/1112 , A61B5/145 , A61B5/14532 , A61B5/4094 , A61B2560/0209 , A61B2560/0412 , A61B2560/0468 , A61B2562/0219 , A61M5/1452 , A61M5/172 , G06F19/34 , G06F19/3418 , H04B13/005
摘要： Receivers, which may be external or implantable, are provided. Aspects of receivers of the invention include the presence of one or more of: a high power-low power module; an intermediary module; a power supply module configured to activate and deactivate one or more power supplies to a high power processing block; a serial peripheral interface bus connecting master and slave blocks; and a multi-purpose connector. Receivers of the invention may be configured to receive a conductively transmitted signal. Also provided are systems that include the receivers, as well as methods of using the same. Additionally systems and methods are disclosed for using a receiver for coordinating with dosage delivery systems.
摘要翻译：提供可能是外部或可植入的接收器。本发明的接收机的方面包括存在一个或多个：高功率低功率模块; 中介模块; 电源模块，被配置为激活和去激活一个或多个电源给高功率处理块; 连接主站和从站的串行外设接口总线; 和多用途连接器。本发明的接收机可以被配置为接收电传送的信号。还提供了包括接收器的系统，以及使用它们的方法。另外公开了使用接收器来配合给药系统的系统和方法。

10. 发明申请

US20120004527A1 Communication System Using an Implantable Device 有权
标题翻译：使用植入式设备的通信系统
公开(公告)号：US20120004527A1
公开(公告)日：2012-01-05
申请号：US13180539
申请日：2011-07-11
申请人： Todd Thompson , Mark Zdeblick , Yashar Behzadi , Benedict Costello , Timothy Robertson , Hooman Hafezi , George Savage
发明人： Todd Thompson , Mark Zdeblick , Yashar Behzadi , Benedict Costello , Timothy Robertson , Hooman Hafezi , George Savage
IPC分类号： A61B5/04 , A61M5/168 , A61N1/365
CPC分类号： A61B5/076 , A61B5/0028 , A61B5/073 , A61B5/14539 , A61B5/4839 , A61B2560/0214 , A61J3/007 , A61N1/37288 , G06F19/00 , G06F19/3418 , H01Q1/273
摘要： The system of the present invention includes an implantable device that can detect high and low frequency current signature. The implantable device can communicate with a communication device that includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, the communication device is activated.
摘要翻译：本发明的系统包括可以检测高频和低频电流签名的可植入装置。可植入装置可以与包括导电元件，电子部件和不同材料形式的部分电源的通信装置进行通信。当与导电流体接触时，通信装置被激活。

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