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1. 发明授权

US08589106B2 Calibration of a handheld diabetes managing device that receives data from a continuous glucose monitor 有权
标题翻译：从连续葡萄糖监测器接收数据的手持式糖尿病管理装置的校准
公开(公告)号：US08589106B2
公开(公告)日：2013-11-19
申请号：US12975769
申请日：2010-12-22
申请人： Timothy Peter Engelhardt , Nikolaus Schmitt , Phillip E. Pash , David Duke , Abhishek Soni
发明人： Timothy Peter Engelhardt , Nikolaus Schmitt , Phillip E. Pash , David Duke , Abhishek Soni
IPC分类号： G01C19/00 , G01C25/00 , G01D18/00 , G01F25/00 , G06F19/00 , A61B5/05 , A61B5/00
CPC分类号： A61B5/14532 , G06F19/00 , G16H40/40
摘要： A method for calibrating a handheld diabetes managing device based on data generated by a continuous glucose monitor. The method can include sampling a current of the continuous glucose monitor at a sampling interval over a time period to generate a plurality of current samples for the time period. The method can also include determining a mean, median and standard deviation of the plurality of current samples. The blood glucose level of the patient can be measured at a first time and a calibration equation that associates the plurality of current samples with the estimated glucose level of the patient based on the measured blood glucose level and the plurality of current samples can be determined when the standard deviation is less than a first threshold and an absolute value of a difference between the mean and median is less than a second threshold.
摘要翻译：一种用于基于由连续葡萄糖监测器生成的数据来校准手持式糖尿病管理装置的方法。该方法可以包括在一段时间内以采样间隔对连续葡萄糖监测器的电流进行采样，以在该时间段内产生多个当前采样。该方法还可以包括确定多个当前样本的平均值，中值和标准偏差。可以在第一时间测量患者的血糖水平，并且可以基于测量的血糖水平和多个当前样本将多个当前样本与患者的估计葡萄糖水平相关联的校准方程可以在标准偏差小于第一阈值，平均值和中值之间的差的绝对值小于第二阈值。

2. 发明申请

US20120166126A1 CALIBRATION OF A HANDHELD DIABETES MANAGING DEVICE THAT RECEIVES DATA FROM A CONTINUOUS GLUCOSE MONITOR 有权
标题翻译：手持式糖尿病管理装置的校准从连续葡萄糖监测器接收数据
公开(公告)号：US20120166126A1
公开(公告)日：2012-06-28
申请号：US12975769
申请日：2010-12-22
申请人： Timothy Peter Engelhardt , Nikolaus Schmitt , Phillip E. Pash , David Duke , Abhishek Soni
发明人： Timothy Peter Engelhardt , Nikolaus Schmitt , Phillip E. Pash , David Duke , Abhishek Soni
IPC分类号： G06F19/00
CPC分类号： A61B5/14532 , G06F19/00 , G16H40/40
摘要： A method for calibrating a handheld diabetes managing device based on data generated by a continuous glucose monitor. The method can include sampling a current of the continuous glucose monitor at a sampling interval over a time period to generate a plurality of current samples for the time period. The method can also include determining a mean, median and standard deviation of the plurality of current samples. The blood glucose level of the patient can be measured at a first time and a calibration equation that associates the plurality of current samples with the estimated glucose level of the patient based on the measured blood glucose level and the plurality of current samples can be determined when the standard deviation is less than a first threshold and an absolute value of a difference between the mean and median is less than a second threshold.
摘要翻译：一种用于基于由连续葡萄糖监测器生成的数据来校准手持式糖尿病管理装置的方法。该方法可以包括在一段时间内以采样间隔对连续葡萄糖监测器的电流进行采样，以在该时间段内产生多个当前采样。该方法还可以包括确定多个当前样本的平均值，中值和标准偏差。可以在第一时间测量患者的血糖水平，并且可以基于测量的血糖水平和多个当前样本将多个当前样本与患者的估计葡萄糖水平相关联的校准方程可以在标准偏差小于第一阈值，平均值和中值之间的差的绝对值小于第二阈值。

3. 发明申请

US20120165639A1 STORAGE OF CALIBRATION DATA AT A CONTINUOUS GLUCOSE MONITOR 审中-公开
标题翻译：在连续葡萄糖监测仪上存储校准数据
公开(公告)号：US20120165639A1
公开(公告)日：2012-06-28
申请号：US12975792
申请日：2010-12-22
申请人： Timothy Peter Engelhardt , Guenter Handwerker , Mark Nierzwick , Gerhard Frisch , Phillip E. Pash
发明人： Timothy Peter Engelhardt , Guenter Handwerker , Mark Nierzwick , Gerhard Frisch , Phillip E. Pash
IPC分类号： A61B5/145
CPC分类号： G16H40/40
摘要： A method for storing data at a continuous glucose monitor is presented. The method includes measuring the blood glucose level of the patient. The method also includes receiving a plurality of physical attributes related to the glucose level of the patient. The method further includes determining calibration data based on the measured blood glucose level and at least one of the plurality of physical attribute samples, the calibration data configured to allow the handheld diabetes managing device to determine the estimated glucose level of the patient based on the plurality of physical attribute samples. Finally, the method includes transmitting the calibration data from the handheld diabetes managing device to the continuous glucose monitor for storage at the continuous glucose monitor. The calibration data and plurality of physical attribute samples can be retrieved by a separate device to determine an estimated glucose level of the patient.
摘要翻译：提出了一种在连续葡萄糖监测器上存储数据的方法。该方法包括测量患者的血糖水平。该方法还包括接收与患者的葡萄糖水平相关的多个物理属性。该方法还包括基于所测量的血糖水平和多个物理属性样本中的至少一个来确定校准数据，所述校准数据被配置为允许手持式糖尿病管理装置基于多个物理属性样本来确定患者的估计的葡萄糖水平的物理属性样本。最后，该方法包括将来自手持式糖尿病管理装置的校准数据传送到连续葡萄糖监测器，以便在连续葡萄糖监测器处储存。校准数据和多个物理属性样本可以由单独的装置检索以确定患者的估计的葡萄糖水平。

4. 发明授权

US08636661B2 Embeddable modules for measuring blood glucose levels 失效
标题翻译：用于测量血糖水平的可嵌入模块
公开(公告)号：US08636661B2
公开(公告)日：2014-01-28
申请号：US12477982
申请日：2009-06-04
申请人： Carol Batman , Blaine Edward Ramey , Timothy Peter Engelhardt , Michel A. Cadio , Steven Kent Moore , Ricky Lee Collins , Michael L. Brown
发明人： Carol Batman , Blaine Edward Ramey , Timothy Peter Engelhardt , Michel A. Cadio , Steven Kent Moore , Ricky Lee Collins , Michael L. Brown
IPC分类号： A61B5/00 , G06F13/12
CPC分类号： A61B5/0002 , A61B5/14532 , A61B5/1495 , A61B2560/0223 , A61B2560/0252 , A61B2560/0443 , A61B2560/045 , A61B2560/0456 , A61B2562/0295 , A61B2562/08 , A61B2562/085
摘要： An embeddable module for measuring a blood glucose level may be embedded in an external host and may comprise a host interface, a microcontroller, an ASIC, a temperature measuring element, and a measurement strip port. The host interface may permit electrical communication between the host and the microcontroller. The microcontroller and ASIC may communicate with each other and may work together to measure the blood glucose level of a blood sample. The measurement strip port may receive a removable measurement strip having the blood sample. The ASIC may communicate with the measurement strip port such that the ASIC may receive signals from the measurement strip port related to the blood glucose level of the blood sample. The temperature measuring element may be in electrical communication with the microcontroller and may measure the temperature of the module and transmit signals to the microcontroller related to the temperature of the module.
摘要翻译：用于测量血糖水平的可嵌入模块可以嵌入在外部主机中，并且可以包括主机接口，微控制器，ASIC，温度测量元件和测量带端口。主机接口可以允许主机和微控制器之间的电气通信。微控制器和ASIC可以彼此通信并且可以一起工作以测量血液样本的血糖水平。测量条端口可以接收具有血液样本的可拆卸测量条。 ASIC可以与测量条端口通信，使得ASIC可以从与血液样本的血糖水平相关的测量条端口接收信号。温度测量元件可以与微控制器电连通，并且可以测量模块的温度并将与模块的温度相关的信号传输到微控制器。

5. 发明申请

US20100312082A1 EMBEDDABLE MODULES FOR MEASURING BLOOD GLUCOSE LEVELS 失效
标题翻译：用于测量血糖水平的可嵌入模块
公开(公告)号：US20100312082A1
公开(公告)日：2010-12-09
申请号：US12477982
申请日：2009-06-04
申请人： Carol Batman , Blaine Edward Ramey , Timothy Peter Engelhardt , Michel Cadio , Steven Kent Moore , Ricky Lee Collins , Michael L. Brown
发明人： Carol Batman , Blaine Edward Ramey , Timothy Peter Engelhardt , Michel Cadio , Steven Kent Moore , Ricky Lee Collins , Michael L. Brown
IPC分类号： A61B5/145 , G06F13/12
CPC分类号： A61B5/0002 , A61B5/14532 , A61B5/1495 , A61B2560/0223 , A61B2560/0252 , A61B2560/0443 , A61B2560/045 , A61B2560/0456 , A61B2562/0295 , A61B2562/08 , A61B2562/085
摘要： An embeddable module for measuring a blood glucose level may be embedded in an external host and may comprise a host interface, a microcontroller, an ASIC, a temperature measuring element, and a measurement strip port. The host interface may permit electrical communication between the host and the microcontroller. The microcontroller and ASIC may communicate with each other and may work together to measure the blood glucose level of a blood sample. The measurement strip port may receive a removable measurement strip having the blood sample. The ASIC may communicate with the measurement strip port such that the ASIC may receive signals from the measurement strip port related to the blood glucose level of the blood sample. The temperature measuring element may be in electrical communication with the microcontroller and may measure the temperature of the module and transmit signals to the microcontroller related to the temperature of the module.
摘要翻译：用于测量血糖水平的可嵌入模块可以嵌入在外部主机中，并且可以包括主机接口，微控制器，ASIC，温度测量元件和测量带端口。主机接口可以允许主机和微控制器之间的电气通信。微控制器和ASIC可以彼此通信并且可以一起工作以测量血液样本的血糖水平。测量条端口可以接收具有血液样本的可拆卸测量条。 ASIC可以与测量条端口通信，使得ASIC可以从与血液样本的血糖水平相关的测量条端口接收信号。温度测量元件可以与微控制器电连通，并且可以测量模块的温度并将与模块的温度相关的信号传输到微控制器。

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