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1. 发明申请

US20050090500A1 Stable polymorph of N-(3-ethynylphenyl)-6, 7-bis (2-methoxyethoxy)-4-quinazolinamine hydrochloride, methods of production, and pharmaceutical uses thereof 有权
标题翻译： N-（3-乙炔基苯基）-6,7-双（2-甲氧基乙氧基）-4-喹唑啉胺盐酸盐的稳定多晶型物，生产方法及其制药用途
公开(公告)号：US20050090500A1
公开(公告)日：2005-04-28
申请号：US10992266
申请日：2004-11-18
申请人： Timothy Norris , Jeffrey Raggon , Richard Connell , James Moyer , Michael Morin , Shama Kajiji , Barbara Foster , Karen Ferrante , Sandra Silberman
发明人： Timothy Norris , Jeffrey Raggon , Richard Connell , James Moyer , Michael Morin , Shama Kajiji , Barbara Foster , Karen Ferrante , Sandra Silberman
IPC分类号： A61K31/517 , A61K45/06 , C07D239/94 , A61K31/498
CPC分类号： C07D239/94 , A61K31/517 , A61K45/06 , A61K2300/00
摘要： The present invention relates to a stable crystalline form of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride designated the B polymorph, its production in essentially pure form, and its use. The invention also relates to the pharmaceutical compositions containing the stable polymorph B form of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine as hydrochloride, as well other forms of the compound, and to methods of treating hyperproliferative disorders, such as cancer, by administering the compound.
摘要翻译：本发明涉及称为B多晶型物的N-（3-乙炔基苯基）-6,7-双（2-甲氧基乙氧基）-4-喹唑啉胺盐酸盐的稳定结晶形式，其基本上纯的形式及其用途。本发明还涉及含有作为盐酸盐的N-（3-乙炔基苯基）-6,7-双（2-甲氧基乙氧基）-4-喹唑啉胺的稳定多晶型物B形式的药物组合物，以及其它形式的化合物，以及通过施用化合物治疗过度增殖性疾病如癌症的方法。

2. 外观设计

USD776486S1 Portable apparatus for cooling and carrying articles 有权
标题翻译：用于冷却和携带物品的便携式设备
公开(公告)号：USD776486S1
公开(公告)日：2017-01-17
申请号：US29488565
申请日：2014-04-21
申请人： Barbara Foster
设计人： Barbara Foster
CPC分类号： F25B21/02 , F25D31/006 , F25D2331/805

3. 发明申请

US20100019640A1 PORTABLE APPARATUS FOR COOLING AND CARRYING ARTICLES 审中-公开
标题翻译：便携式装置冷藏和运送文章
公开(公告)号：US20100019640A1
公开(公告)日：2010-01-28
申请号：US12177198
申请日：2008-07-22
申请人： Barbara Foster
发明人： Barbara Foster
IPC分类号： A47B96/04
CPC分类号： F25B21/02 , F25D31/006 , F25D2331/805
摘要： Disclosed is a portable apparatus for cooling and carrying articles. The portable apparatus comprises a first enclosure, a second enclosure, a refrigeration system and a power source. The first enclosure includes a first inner space and the second enclosure includes a second inner space. The second enclosure is detachably attached to the first enclosure to configure a closed inner space by joining the first inner space and the second inner space. The closed inner space is capable of accommodating the articles therein. Further, the refrigeration system is disposed within at least one of the first enclosure and the second enclosure for cooling the closed inner space. Furthermore, the power source is detachably attached to at least one of the first enclosure and the second enclosure. The power source is capable of supplying power to the refrigeration system for cooling the closed inner space, thereby cooling the articles accommodated therein.
摘要翻译：公开了用于冷却和携带物品的便携式设备。便携式设备包括第一外壳，第二外壳，制冷系统和电源。第一外壳包括第一内部空间，第二外壳包括第二内部空间。第二外壳可拆卸地连接到第一外壳，以通过连接第一内部空间和第二内部空间来构造封闭的内部空间。封闭的内部空间能够容纳物品。此外，制冷系统设置在第一外壳和第二外壳中的至少一个中，用于冷却封闭的内部空间。此外，电源可拆卸地附接到第一外壳和第二外壳中的至少一个。电源能够向制冷系统供电以冷却封闭的内部空间，从而冷却容纳在其中的物品。

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