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1. 发明授权

US06638233B2 Apparatus and methods for material capture and removal 有权
公开(公告)号：US06638233B2
公开(公告)日：2003-10-28
申请号：US09377884
申请日：1999-08-19
申请人： Tim Corvi , Stephen Boyd , Brett Follmer , John G. Stine , David W. Snow , Darren G. Doud
发明人： Tim Corvi , Stephen Boyd , Brett Follmer , John G. Stine , David W. Snow , Darren G. Doud
IPC分类号： A61B1000
CPC分类号： A61B10/0275 , A61B10/04
摘要： Catheters, kits, and methods are provided for removing material from a body lumen. The catheters and methods may be used in a variety of body lumens, including but not limited to coronary and other arteries. In general, the catheter has a cutting element that cuts material while the material is engaged by a material capture device on the catheter body. Preferably, the material capture device tensions the material during cutting, which reduces the amount of cutting force required. The material capture device typically follows a path that draws material into the catheter body. Preferably, but not necessarily, the material capture device may be arranged on the catheter body to advance along a path outwardly from the catheter body into the material and then inwardly towards the catheter body to tension the material. The cutting element on the catheter body moves between a first position and a second position to cut the material while in tension.

2. 发明授权

US08784333B2 Apparatus and methods for material capture and removal 有权
标题翻译：用于材料捕获和去除的装置和方法
公开(公告)号：US08784333B2
公开(公告)日：2014-07-22
申请号：US12357037
申请日：2009-01-21
申请人： Tim Corvi , Stephen Boyd , Brett Follmer , John G. Stine , David W. Snow , Darren G. Doud
发明人： Tim Corvi , Stephen Boyd , Brett Follmer , John G. Stine , David W. Snow , Darren G. Doud
IPC分类号： A61B10/00 , A61B17/22 , A61D1/02
CPC分类号： A61B10/0275 , A61B10/04
摘要： Catheters, kits, and methods are provided for removing material from a body lumen. The catheters and methods may be used in a variety of body lumens, including but not limited to coronary and other arteries. In general, the catheter has a cutting element that cuts material while the material is engaged by a material capture device on the catheter body. Preferably, the material capture device tensions the material during cutting, which reduces the amount of cutting force required. The material capture device typically follows a path that draws material into the catheter body. Preferably, but not necessarily, the material capture device may be arranged on the catheter body to advance along a path outwardly from the catheter body into the material and then inwardly towards the catheter body to tension the material. The cutting element on the catheter body moves between a first position and a second position to cut the material while in tension.
摘要翻译：提供导管，套件和方法用于从体腔去除材料。导管和方法可以用于各种体腔，包括但不限于冠状动脉和其他动脉。通常，导管具有切割材料，该切割元件在材料通过导管主体上的材料捕获装置接合时切割材料。优选地，材料捕获装置在切割期间张紧材料，这减少了所需的切割力的量。材料捕获装置通常遵循将材料拉入导管主体的路径。优选但不是必需的，材料捕获装置可以布置在导管主体上，以沿着从导管主体向外的路径前进到材料中，然后向内朝向导管主体拉伸材料。导管主体上的切割元件在第一位置和第二位置之间移动，以在张力下切割材料。

3. 发明申请

US20090187203A1 APPARATUS AND METHODS FOR MATERIAL CAPTURE AND REMOVAL 有权
公开(公告)号：US20090187203A1
公开(公告)日：2009-07-23
申请号：US12357037
申请日：2009-01-21
申请人： Tim Corvi , Stephen Boyd , Brett Follmer , John G. Stine , David W. Snow , Darren G. Doud
发明人： Tim Corvi , Stephen Boyd , Brett Follmer , John G. Stine , David W. Snow , Darren G. Doud
IPC分类号： A61B17/22
CPC分类号： A61B10/0275 , A61B10/04
摘要： Catheters, kits, and methods are provided for removing material from a body lumen. The catheters and methods may be used in a variety of body lumens, including but not limited to coronary and other arteries. In general, the catheter has a cutting element that cuts material while the material is engaged by a material capture device on the catheter body. Preferably, the material capture device tensions the material during cutting, which reduces the amount of cutting force required. The material capture device typically follows a path that draws material into the catheter body. Preferably, but not necessarily, the material capture device may be arranged on the catheter body to advance along a path outwardly from the catheter body into the material and then inwardly towards the catheter body to tension the material. The cutting element on the catheter body moves between a first position and a second position to cut the material while in tension.

4. 发明申请

US20060235334A1 Apparatus and methods for material capture and removal 审中-公开
公开(公告)号：US20060235334A1
公开(公告)日：2006-10-19
申请号：US11455995
申请日：2006-06-19
申请人： Tim Corvi , Stephen Boyd , Brett Follmer , John Stine , David Snow , Darren Doud
发明人： Tim Corvi , Stephen Boyd , Brett Follmer , John Stine , David Snow , Darren Doud
IPC分类号： A61B10/00
CPC分类号： A61B10/0275 , A61B10/04 , A61B17/320783 , A61B2017/320064 , A61B2017/320791
摘要： Catheters, kits, and methods are provided for removing material from a body lumen. The catheters and methods may be used in a variety of body lumens, including but not limited to coronary and other arteries. In general, the catheter has a cutting element that cuts material while the material is engaged by a material capture device on the catheter body. Preferably, the material capture device tensions the material during cutting, which reduces the amount of cutting force required. The material capture device typically follows a path that draws material into the catheter body. Preferably, but not necessarily, the material capture device may be arranged on the catheter body to advance along a path outwardly from the catheter body into the material and then inwardly towards the catheter body to tension the material. The cutting element on the catheter body moves between a first position and a second position to cut the material while in tension.

5. 发明授权

US06447525B2 Apparatus and methods for removing material from a body lumen 有权
标题翻译：从体腔去除材料的装置和方法
公开(公告)号：US06447525B2
公开(公告)日：2002-09-10
申请号：US09377894
申请日：1999-08-19
申请人： Brett Follmer , Stephen Boyd , Eric Willis
发明人： Brett Follmer , Stephen Boyd , Eric Willis
IPC分类号： A61B1722
CPC分类号： A61B10/06 , A61B17/3207 , A61B17/32075 , A61B17/320783 , A61B2017/003 , A61B2017/320791
摘要： Devices, methods, and kits for removing material from a body lumen. The devices and methods may be used in a variety of body lumens, including but not limited to coronary arteries and other blood vessels. In general, the device or catheter has a scoop-shaped cutting blade mounted on a catheter body for removing material from a body lumen. The cutting blade has a cutting edge that travels a curved path about a pivot point of the blade, preferably moving in an outward direction from the catheter body to engage the target material for removal. The scoop-shaped blade has a collection surface located behind the cutting edge to collect material removed from said body lumen. Advantageously, a scoop-shaped cutting blade according to the present invention facilitates material engagement and the collection surface may be used to bring material back into the catheter body as the blade begins to part-off material. The cutting blade is usually mounted to move in an inward direction towards the catheter body after the cutting edge has engaged the material. The cutting blade can also more easily engage occlusive material that is compressed against the body lumen wall.
摘要翻译：用于从体腔去除材料的装置，方法和试剂盒。装置和方法可以用于各种体腔，包括但不限于冠状动脉和其他血管。通常，装置或导管具有安装在导管主体上的勺形切割刀片，用于从体腔去除材料。切割刀片具有围绕叶片的枢转点行进弯曲路径的切割边缘，优选地从导管主体沿向外的方向移动以接合目标材料以便移除。勺形刀片具有位于切割边缘后面的收集表面，以收集从所述体腔移除的材料。有利地，根据本发明的勺形切割刀片有助于材料接合，并且收集表面可以用于当刀片开始分离材料时将材料返回到导管主体中。切割刀片通常安装成在切削刃已经接合材料之后沿向内的方向朝向导管主体移动。切割刀片还可以更容易地接合被压靠在体腔壁上的封闭材料。

6. 发明授权

US08911459B2 Debulking catheters and methods 有权
标题翻译：去污导管和方法
公开(公告)号：US08911459B2
公开(公告)日：2014-12-16
申请号：US13536497
申请日：2012-06-28
申请人： John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
发明人： John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
IPC分类号： A61B17/22 , A61B17/32 , A61B17/00 , A61B17/3207 , A61B10/02 , A61B10/04
CPC分类号： A61B17/320758 , A61B10/04 , A61B17/32075 , A61B17/320783 , A61B2010/0225 , A61B2017/00685 , A61B2017/320032 , A61B2017/320791
摘要： A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof.
摘要翻译：从血流腔去除材料的方法包括提供具有切割元件和开口的装置，所述切割元件可相对于所述开口移动。该方法然后包括将装置通过患者的血管系统推进到血流腔。最后，该方法包括相对于血液流动腔移动切割元件和开口，使得当切割元件和开口移动通过血流腔时，连续片材被切割元件切断并引导到开口中，连续切断的材料被引导到装置中以从患者身上取出。该方法可以包括提供具有可旋转切割器的装置，其在一些实施例中不平行于装置的纵向轴线，是可移动的，具有缩回和展开位置或其任何组合。

7. 发明授权

US08226674B2 Debulking catheters and methods 有权
标题翻译：去污导管和方法
公开(公告)号：US08226674B2
公开(公告)日：2012-07-24
申请号：US12757291
申请日：2010-04-09
申请人： John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
发明人： John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
IPC分类号： A61B17/22 , A61D1/02
CPC分类号： A61B17/320758 , A61B10/04 , A61B17/32075 , A61B17/320783 , A61B2010/0225 , A61B2017/00685 , A61B2017/320032 , A61B2017/320791
摘要： A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof. The method may further include forcing the opening toward the wall of the vascular site after the advancing step and before the moving step.
摘要翻译：从血流腔去除材料的方法包括提供具有切割元件和开口的装置，所述切割元件可相对于所述开口移动。该方法然后包括将装置通过患者的血管系统推进到血流腔。最后，该方法包括相对于血液流动腔移动切割元件和开口，使得当切割元件和开口移动通过血流腔时，连续片材被切割元件切断并引导到开口中，连续切断的材料被引导到装置中以从患者身上取出。该方法可以包括提供具有可旋转切割器的装置，其在一些实施例中不平行于装置的纵向轴线，是可移动的，具有缩回和展开位置或其任何组合。该方法还可以包括在推进步骤之后和移动步骤之前迫使开口朝向血管部位的壁。

8. 发明申请

US20120330336A1 DEBULKING CATHETERS AND METHODS 有权
标题翻译：破坏导管和方法
公开(公告)号：US20120330336A1
公开(公告)日：2012-12-27
申请号：US13536497
申请日：2012-06-28
申请人： John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
发明人： John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
IPC分类号： A61B17/22
CPC分类号： A61B17/320758 , A61B10/04 , A61B17/32075 , A61B17/320783 , A61B2010/0225 , A61B2017/00685 , A61B2017/320032 , A61B2017/320791
摘要： A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof.
摘要翻译：从血流腔去除材料的方法包括提供具有切割元件和开口的装置，所述切割元件可相对于所述开口移动。该方法然后包括将装置通过患者的血管系统推进到血流腔。最后，该方法包括相对于血液流动腔移动切割元件和开口，使得当切割元件和开口移动通过血流腔时，连续片材被切割元件切断并引导到开口中，连续切断的材料被引导到装置中以从患者身上取出。该方法可以包括提供具有可旋转切割器的装置，其在一些实施例中不平行于装置的纵向轴线，是可移动的，具有缩回和展开位置或其任何组合。

9. 发明申请

US20100198240A1 DEBULKING CATHETERS AND METHODS 有权
标题翻译：破坏导管和方法
公开(公告)号：US20100198240A1
公开(公告)日：2010-08-05
申请号：US12757291
申请日：2010-04-09
申请人： John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
发明人： John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
IPC分类号： A61B17/22 , A61B17/06
CPC分类号： A61B17/320758 , A61B10/04 , A61B17/32075 , A61B17/320783 , A61B2010/0225 , A61B2017/00685 , A61B2017/320032 , A61B2017/320791
摘要： A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof. The method may further include forcing the opening toward the wall of the vascular site after the advancing step and before the moving step.
摘要翻译：从血流腔去除材料的方法包括提供具有切割元件和开口的装置，所述切割元件可相对于所述开口移动。该方法然后包括将装置通过患者的血管系统推进到血流腔。最后，该方法包括相对于血液流动腔移动切割元件和开口，使得当切割元件和开口移动通过血流腔时，连续片材被切割元件切断并引导到开口中，连续切断的材料被引导到装置中以从患者身上取出。该方法可以包括提供具有可旋转切割器的装置，其在一些实施例中不平行于装置的纵向轴线，是可移动的，具有缩回和展开位置或其任何组合。该方法还可以包括在推进步骤之后和移动步骤之前迫使开口朝向血管部位的壁。

10. 发明授权

US07708749B2 Debulking catheters and methods 有权
标题翻译：去污导管和方法
公开(公告)号：US07708749B2
公开(公告)日：2010-05-04
申请号：US11012876
申请日：2004-12-14
申请人： John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
发明人： John B. Simpson , Himanshu Patel , Greg Stine , Brett Follmer , Michael H. Rosenthal , Mehrdad Farhangnia
IPC分类号： A61B17/22 , A61D1/02
CPC分类号： A61B17/320758 , A61B10/04 , A61B17/32075 , A61B17/320783 , A61B2010/0225 , A61B2017/00685 , A61B2017/320032 , A61B2017/320791
摘要： A method of removing material from a blood flow lumen includes providing a device having a cutting element and an opening, the cutting element being movable relative to the opening. The method then includes advancing the device through a patient's vascular system to the blood flow lumen. Finally, the method involves moving the cutting element and the opening relative to the blood flow lumen so that a continuous piece of material is severed by the cutting element and directed into the opening as the cutting element and opening move through the blood flow lumen, the continuous piece of severed material being directed into the device for removal from the patient. The method may include providing a device having a rotatable cutter that, in some embodiments, is not parallel to the longitudinal axis of the device, is movable, has retracted and deployed positions, or any combination thereof. The method may further include forcing the opening toward the wall of the vascular site after the advancing step and before the moving step.
摘要翻译：从血流腔去除材料的方法包括提供具有切割元件和开口的装置，所述切割元件可相对于所述开口移动。该方法然后包括将装置通过患者的血管系统推进到血流腔。最后，该方法包括相对于血液流动腔移动切割元件和开口，使得当切割元件和开口移动通过血流腔时，连续片材被切割元件切断并引导到开口中，连续切断的材料被引导到装置中以从患者身上取出。该方法可以包括提供具有可旋转切割器的装置，其在一些实施例中不平行于装置的纵向轴线，是可移动的，具有缩回和展开位置或其任何组合。该方法还可以包括在推进步骤之后和移动步骤之前迫使开口朝向血管部位的壁。

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