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1. 发明授权

US06403067B1 Stable emulsions for cosmetic products 失效
标题翻译：化妆品稳定乳液
公开(公告)号：US06403067B1
公开(公告)日：2002-06-11
申请号：US09575483
申请日：2000-05-19
申请人： Thomas Schamper , Suman Kumar Chopra , Bhal Moghe , John Carl-Frederick Brahms , Mardoqueo Bustos , Peter Hilliard, Jr. , Marie Johansson , Claudo Ortiz , Christine Popoff
发明人： Thomas Schamper , Suman Kumar Chopra , Bhal Moghe , John Carl-Frederick Brahms , Mardoqueo Bustos , Peter Hilliard, Jr. , Marie Johansson , Claudo Ortiz , Christine Popoff
IPC分类号： A61K732
CPC分类号： A61Q15/00 , A61K8/06 , A61K8/894
摘要： Low water emulsions are described which are useful for antiperspirants and/or deodorants wherein the emulsions are made by combining (I) 15-33% of an external phase comprising: (a) 1-25% of an organic ester having a refractive index in the range of 1.43-1.60 and capable of releasing an antiperspirant active to achieve a specified conductivity; (b) a sufficient amount of a silicone copolyol to achieve a solids content of 0.25-10%; (c) a sufficient amount of a volatile silicone to achieve a total amount of the external phase as 15-33%; (c) 0-5% of a silicone elastomer (on an actives basis); and (d) 0-15% of at least one emollient; and (II) 67-85% of an internal phase comprising: (a) an effective amount of at least one cosmetically active ingredient; (b) a sufficient amount of a solvent component to dissolve the cosmetically active ingredient with a maximum amount being about 80%; (c) 0.5-15 % of water optionally containing up to 30% of an ionizable salt soluble in water; (d) 0-5 % of a non-ionic emulsifier; and (e) 0-10% ethanol; wherein: (1) the final refractive index of the composition is in the range of 1.42-1.52; and (2) the conductance of the composition is at least 250 micro Siemens/cm/ml at a loading of at least 7% by weight level of antiperspirant active.
摘要翻译：描述了可用于止汗剂和/或除臭剂的低水乳剂，其中乳液通过将（I）15-33％的外相组合制备，所述外相包含：（a）1-25％的具有折射率的有机酯范围为1.43-1.60，能够释放止汗活性物质达到规定的电导率; （b）足够量的硅氧烷共聚多元醇以获得0.25-10％的固体含量; （c）足量的挥发性硅酮，以达到外相总量的15-33％; （c）0-5％的硅氧烷弹性体（基于活性物质）; 和（d）至少一种润肤剂的0-15％; 和（II）67-85％的内相，其包含：（a）有效量的至少一种化妆品活性成分; （b）足够量的溶剂组分以最大量为约80％溶解化妆品活性成分; （c）0.5-15％的水，任选地含有最多30％的可溶于水的可电离盐; （d）0-5％的非离子乳化剂; 和（e）0-10％乙醇; 其中：（1）组合物的最终折射率在1.42-1.52的范围内; 和（2）组合物的电导率至少为250微西门子/厘米/毫升，以至少7重量％的止汗活性剂的负荷。

2. 发明授权

US06485716B1 High efficacy liquid gel product 失效
标题翻译：高效液体凝胶产品
公开(公告)号：US06485716B1
公开(公告)日：2002-11-26
申请号：US09971876
申请日：2001-10-05
申请人： Lin Fei , Suman Chopra , Eric Guenin , Peter Hilliard, Jr. , Jairajh Mattai , Neeta Patel
发明人： Lin Fei , Suman Chopra , Eric Guenin , Peter Hilliard, Jr. , Jairajh Mattai , Neeta Patel
IPC分类号： A61K732
CPC分类号： A61K8/894 , A61K8/042 , A61K8/046 , A61K8/26 , A61K8/31 , A61K8/33 , A61K8/34 , A61K8/375 , A61K8/891 , A61K2800/262 , A61Q15/00
摘要： The invention is a clear, elastomer-free, gel composition comprising: (a) 0.1-25 weight % of an antiperspirant active having a low metal to chloride ratio in the range of 0.9-1.3: 1; (b) 9-23.95 weight % of one or more volatile silicones having a flash point of 100 degrees C or less; (c) 0.05-0.5 weight % of a silicone surfactant having an HLB value≦8; (d) 30-70 weight % water; (e) 0-50 weight % selected water soluble organic solvents; and (f) 0-10 weight % of an emollient; wherein the composition is a liquid gel having a viscosity in the range of 5-50,000 centipoise and a ratio of oil phase to water phase in the range of 10:90 to 24:76.
摘要翻译：本发明是一种透明的，无弹性体的凝胶组合物，其包含：（a）0.1至25重量％的低金属与氯化物之比在0.9-1.3:1范围内的止汗活性剂; （b）9-23.95重量％的闪点为100℃以下的一种或多种挥发性有机硅; （c）0.05-0.5重量％的具有HLB值<= 8的硅氧烷表面活性剂; （d）30-70重量％的水; （e）0-50重量％选择的水溶性有机溶剂; 和（f）0-10重量％的润肤剂; 其中所述组合物是粘度在5-50,000厘泊范围内的液体凝胶，油相与水相的比例在10:90至24:76的范围内。

3. 发明授权

US07311898B2 High efficacy, low irritation aluminum salts and related products 有权
标题翻译：高效，低刺激性的铝盐及相关产品
公开(公告)号：US07311898B2
公开(公告)日：2007-12-25
申请号：US11080913
申请日：2005-03-15
申请人： Xiaozhong Tang , Lin Fei , Suman Chopra , Peter Hilliard, Jr.
发明人： Xiaozhong Tang , Lin Fei , Suman Chopra , Peter Hilliard, Jr.
IPC分类号： A61Q15/00 , A61K8/00 , A61K8/02
CPC分类号： A61K8/895 , A61K8/0229 , A61K8/046 , A61K8/26 , A61K8/44 , A61K8/894 , A61Q15/00
摘要： A zirconium-free aluminum salt which: (a) has an aluminum to chloride molar ratio in the range of 0.5-2.5:1; (b) comprises a nitrogen containing buffering material in an amount such that the ratio of nitrogen containing material to aluminum is the range of 0.05-0.26:1, and which nitrogen containing material is selected from the group consisting of a nitrogen containing buffering material of formula where n is a number in the range of 1-20, and each of R1, R2, and R3 is independently selected from the group consisting of hydrogen, methyl and ethyl; and (c) the salt has a pH in the range of 2-4 at a concentration of 15%; wherein the salt is free of any other halide scavenging material and has a value of at least 0.50 for the ratio calculated as: area of Peak 5/total area under Peak 2+Peak 3+Peak 4+Peak 5.
摘要翻译：一种无锆铝盐，其：（a）铝与氯的摩尔比在0.5-2.5:1的范围内; （b）包括含氮缓冲材料，其含量使得含氮材料与铝的比例为0.05-0.26:1，并且所述含氮材料选自含氮缓冲材料的氮其中n是1-20范围内的数字，并且R 1，R 2和R 3 3中的每一个独立地被选择由氢，甲基和乙基组成的组; 和（c）盐的浓度为15％时的pH在2-4范围内; 其中盐不含任何其它卤化物清除材料，并且对于以下计算的比率，其值为至少0.50：峰5的面积/峰2 +峰3 +峰4 +峰5之间的总面积。

4. 发明授权

US06375937B1 Antiperspirant salts for enhanced cosmetic products 失效
标题翻译：用于增强化妆品的止汗盐
公开(公告)号：US06375937B1
公开(公告)日：2002-04-23
申请号：US09693231
申请日：2000-10-20
申请人： Suman Chopra , Xiaozhong Tang , Peter Hilliard, Jr.
发明人： Suman Chopra , Xiaozhong Tang , Peter Hilliard, Jr.
IPC分类号： A61K737
CPC分类号： A61Q15/00 , A61K8/28 , A61K8/44
摘要： This invention comprises aluminum zirconium salts which have a metal to chloride molar ratio in the range of 0.9-1.2:1 and a glycine:zirconium molar ratio greater than 1.3:1 and antiperspirant compositions made with such salts.
摘要翻译：本发明包括具有0.9-1.2:1范围内的金属氯化物摩尔比和甘氨酸：锆摩尔比大于1.3:1的铝锆盐和由这些盐制成的止汗组合物。

5. 发明授权

US6007799A Clear cosmetic gel composition 失效
标题翻译：透明的化妆品凝胶组成
公开(公告)号：US6007799A
公开(公告)日：1999-12-28
申请号：US689814
申请日：1996-08-14
申请人： Wilson Lee , Kathy Potechin , Robert J. Bianchini , Peter Hilliard, Jr.
发明人： Wilson Lee , Kathy Potechin , Robert J. Bianchini , Peter Hilliard, Jr.
IPC分类号： A61K8/06 , A61K8/28 , A61K8/894 , A61K8/898 , A61Q15/00 , A61K7/32 , A61K7/00
CPC分类号： A61K8/064 , A61K8/042 , A61K8/28 , A61K8/894 , A61Q15/00 , A61K2800/262
摘要： Disclosed is a clear cosmetic gel composition in the form of a water-in-oil emulsion, and methods of forming and of using the composition. The composition has a water-based phase containing water, a cosmetically active ingredient, and at least one coupling agent; and an oil-based phase containing a material having a refractive index in the range of 1.40-1.50, silicone fluids and an alkoxylated, alkyl substituted siloxane surface active agent (e.g., dimethicone copolyol). The composition has a refractive index in a range of 1.4026 to 1.4150. Where the cosmetically active ingredient is an antiperspirant active ingredient, the composition can be an antiperspirant gel (e.g., soft gel) composition. In the refractive index range of the present invention, increased amounts of, e.g., antiperspirant active ingredient, and other high-refractive-index materials providing cosmetic benefits, can be incorporated in the water and oil phases of the composition while still achieving a clear composition. The composition can also include polypropylene glycols (e.g., tripropylene glycol), as part of the water-based phase, to provide a composition having reduced tackiness and reduced whitening (decreased residue); this composition is also mild (reduced skin irritation potential) relative to comparable commercial products.
摘要翻译：公开了一种油包水乳液形式的透明化妆品凝胶组合物，以及形成和使用该组合物的方法。所述组合物具有含水的水相，化妆品活性成分和至少一种偶联剂; 和含有折射率在1.40-1.50范围内的材料的油相，硅氧烷流体和烷氧基化烷基取代的硅氧烷表面活性剂（例如聚二甲基硅氧烷共聚醇）。该组合物的折射率在1.4026至1.4150的范围内。当化妆品活性成分是止汗活性成分时，组合物可以是止汗凝胶（例如软凝胶）组合物。在本发明的折射率范围内，可以在组合物的水相和油相中加入增加量的例如止汗活性成分和提供化妆品益处的其它高折射率材料，同时仍然获得清楚的组成。组合物还可以包括作为水相的一部分的聚丙二醇（例如三丙二醇），以提供具有降低的粘性和减少白化（减少的残余物）的组合物。相对于可比较的商品，该组合物也是轻度（降低皮肤刺激潜力）。

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