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1. 发明授权

US09180258B2 Autoinjector 有权
标题翻译：自动进样器
公开(公告)号：US09180258B2
公开(公告)日：2015-11-10
申请号：US13581564
申请日：2011-03-03
申请人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20 , A61M5/24
CPC分类号： A61M5/3287 , A61M5/2033 , A61M5/24 , A61M5/3202 , A61M5/3204 , A61M5/3234 , A61M5/326 , A61M2005/202 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2407 , A61M2005/2496 , A61M2005/3267
摘要： An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate housing arranged to contain a syringe, a proximal end (P) with an orifice, wherein the syringe is slidably arranged with respect to the housing. A drive spring upon activation pushes the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), and operates the syringe to supply the dose of medicament (M). An activating means locks the drive spring in a compressed state. The housing distal and a proximal portions are connected by a hinge, and are rotatable about the hinge between an aligned position and a maximum opening angle. A loading bay for holding the syringe is arranged in the proximal portion.
摘要翻译：提供了一种用于施用剂量的液体药物（M）的自动注射器，其具有布置成容纳注射器的细长壳体，具有孔口的近端（P），其中所述注射器相对于所述壳体可滑动地布置。激活时的驱动弹簧将针从壳体内的覆盖位置推入通过孔口并通过近端（P）的前进位置，并操作注射器以供应剂量的药物（M）。激活装置将驱动弹簧锁定在压缩状态。壳体远端和近端部分通过铰链连接，并且可以在对准位置和最大开启角度之间围绕铰链旋转。用于保持注射器的装载隔间布置在近端部分中。

2. 发明授权

US09155837B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09155837B2
公开(公告)日：2015-10-13
申请号：US13580216
申请日：2011-03-03
申请人： Thomas Mark Kemp , Douglas Jennings , Peter Scudamore , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Peter Scudamore , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/24 , A61M5/32
CPC分类号： A61M5/3204 , A61M5/2033 , A61M5/24 , A61M5/3202 , A61M5/3234 , A61M5/326 , A61M2005/202 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2407 , A61M2005/2496 , A61M2005/3267
摘要： An auto-injector with an interlock mechanism for defining an operation sequence in a manner to allow a lateral trigger button to be operated when a proximal end of the auto-injector is pressed against an injection site. A detector is arranged inside an elongate housing of the auto-injector at the proximal end and slidable in longitudinal direction and biased by a detector spring. A dog is arranged at the trigger button and wherein at least one longitudinal bar is provided, at least one of the bars slidable in longitudinal direction and coupled to the detector for distal movement. A recess for the dog is provided in the bar for allowing the trigger button to be pressed when the detector means is being pushed into the auto-injector and wherein otherwise the dog is engaged with the bar in a manner to prevent the trigger button from being pressed.
摘要翻译：一种具有互锁机构的自动注射器，用于当自动注射器的近端压靠注射部位时，以允许横向触发按钮被操作的方式限定操作顺序。检测器位于近端的自动注射器的细长壳体的内侧，并可在纵向方向上滑动并被检测器弹簧偏压。在触发按钮上布置有狗，并且其中提供至少一个纵向杆，所述杆中的至少一个在纵向方向上可滑动并且联接到所述检测器用于远端运动。在所述杆中设置用于所述狗的凹槽，用于当所述检测器装置被推入所述自动注射器中时允许所述触发按钮被按压，并且其中所述狗以与所述杆接合以防止所述触发按钮成为按下。

3. 发明申请

US20130150800A1 Auto-Injector 有权
标题翻译：自动进样器
公开(公告)号：US20130150800A1
公开(公告)日：2013-06-13
申请号：US13580216
申请日：2011-03-03
申请人： Thomas Mark Kemp , Douglas Jennings , Peter Scudamore , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Peter Scudamore , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/32
CPC分类号： A61M5/3204 , A61M5/2033 , A61M5/24 , A61M5/3202 , A61M5/3234 , A61M5/326 , A61M2005/202 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2407 , A61M2005/2496 , A61M2005/3267
摘要： The invention relates to an auto-injector with an interlock mechanism for defining an operation sequence of the auto-injector (1) in a manner to allow a lateral trigger button (16) to be operated only when a proximal end (P) of the auto-injector (1) is pressed against an injection site, wherein a detector means (18) is arranged inside an elongate housing (2) of the auto-injector (1) at the proximal end (P), the detector means (18) slidable in longitudinal direction and biased by a detector spring (19) into a position with the detector means (18) protruding beyond the proximal end (P), wherein a dog (16.2) is arranged at the trigger button (16) and wherein at least one longitudinal bar (18.1, 21) is provided, at least one of the bars (21) slidable in longitudinal direction and coupled to the detector means (18) for joint movement at least in distal direction (D), wherein a recess (21.1) for the dog (16.2) is provided in the bar (21) for allowing the trigger button (16) to be pressed when the detector means (18) is being pushed into the auto-injector (1) and wherein otherwise the dog (16.2) is engaged with the bar (21) in a manner to prevent the trigger button (16) from being pressed.
摘要翻译：本发明涉及一种具有互锁机构的自动注射器，该互锁机构用于以仅允许侧向触发按钮（16）的近端（P）运行的方式来限定自动注射器（1）的操作顺序，自动注射器（1）被压靠在注射部位上，其中检测器装置（18）布置在近端（P）的自动注射器（1）的细长壳体（2）的内部，检测器装置（18））能够在纵向方向上滑动并被检测器弹簧（19）偏压到探测器装置（18）突出超出近端（P）的位置，其中，一个狗（16.2）布置在触发按钮（16）处，并且其中提供至少一个纵向杆（18.1,21），所述杆（21）中的至少一个可在纵向方向上滑动并联接到所述检测器装置（18），用于至少在远端方向（D）进行接合运动，其中凹部用于狗（16.2）的（21.1）设置在杆（21）中，用于允许触发按钮（16）被按压，在检测器装置（18）被推入自动注射器（1）中，并且其中，狗（16.2）以防止触发按钮（16）被按压的方式与杆（21）接合。

4. 发明申请

US20130138048A1 AUTOINJECTOR 有权
公开(公告)号：US20130138048A1
公开(公告)日：2013-05-30
申请号：US13581564
申请日：2011-03-03
申请人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
IPC分类号： A61M5/32
CPC分类号： A61M5/3287 , A61M5/2033 , A61M5/24 , A61M5/3202 , A61M5/3204 , A61M5/3234 , A61M5/326 , A61M2005/202 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2407 , A61M2005/2496 , A61M2005/3267
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament (M), comprising: an elongate housing arranged to contain a syringe, the housing having a distal end (D) and a proximal end (P) with an orifice, wherein the syringe is slidably arranged with respect to the housing, a drive spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), and operating the syringe to supply the dose of medicament (M), and activating means arranged to lock the drive spring in a compressed state and capable of releasing the drive spring for injection, wherein the elongate housing comprises a distal portion and a proximal portion connected by a hinge, the portions rotatable about the hinge between an aligned position and a maximum opening angle, wherein the drive spring may be compressed by rotating the portions towards the maximum opening angle, wherein the activating means are arranged to lock the drive spring in the compressed state when the portions are rotated at least almost to the maximum opening angle and wherein a loading bay for holding the syringe is arranged in the proximal portion.
摘要翻译：本发明涉及一种用于施用剂量的液体药物（M）的自动注射器，其包括：布置成容纳注射器的细长壳体，所述壳体具有远端（D）和近端（P），所述近端具有孔，其中所述注射器相对于所述壳体可滑动地布置;驱动弹簧，其能够在启动时：将所述针从所述壳体内的覆盖位置推入到穿过所述孔口并经过所述近端（P）的前进位置，并且操作所述注射器提供剂量的药物（M），以及激活装置，其布置成将所述驱动弹簧锁定在压缩状态并且能够释放用于注射的驱动弹簧，其中所述细长壳体包括远端部分和近端部分铰链，所述部分可以在对准位置和最大开启角度之间围绕所述铰链旋转，其中所述驱动弹簧可以通过将所述部分朝向最大开启角度旋转而被压缩，其中所述动作当所述部分至少几乎旋转到最大开启角度时，所述静止装置被布置成将所述驱动弹簧锁定在压缩状态，并且其中用于保持所述注射器的装载间隔布置在所述近端部分中。

5. 发明授权

US09233214B2 Injection device 有权
标题翻译：注射装置
公开(公告)号：US09233214B2
公开(公告)日：2016-01-12
申请号：US13581566
申请日：2011-03-03
申请人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20 , A61M5/24
CPC分类号： A61M5/322 , A61M5/2033 , A61M5/24 , A61M5/3202 , A61M5/3204 , A61M5/3234 , A61M5/326 , A61M2005/202 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2407 , A61M2005/2496 , A61M2005/3267
摘要： An injection device includes a syringe with a hollow needle and a stopper for sealing the syringe and displacing a medicament stored in the syringe. An arrangement for transferring a translation of a drive means to a plunger for pushing against the stopper includes a release latch pivoted at one end and connected to either the drive means or the plunger. The other end of the release latch engages the other one of the drive means or the plunger. The non-pivoted end of the release latch disengages by rotation upon contact between a ramp and another component when the stopper has displaced most of a predefined medicament dose. The release latch is long enough to provide a clearance between the plunger and the drive means when engaged to allow the plunger, stopper and needle to be retracted inside the syringe or a housing after disengaging the release latch.
摘要翻译：注射装置包括具有中空针的注射器和用于密封注射器并使存储在注射器中的药物移位的止动件。用于将驱动装置的平移传递到用于推动止动件的柱塞的装置包括在一端枢转并连接到驱动装置或柱塞的释放闩锁。释放闩锁的另一端接合驱动装置或柱塞中的另一端。当止动器已经取代大部分预定的药物剂量时，释放闩锁的非转动端部通过斜面和另一部件之间的接触时的旋转而脱离。释放闩锁足够长以在接合时提供柱塞和驱动装置之间的间隙，以允许柱塞，止动器和针在分离释放闩锁之后在注射器或壳体内缩回。

6. 发明申请

US20130138049A1 INJECTION DEVICE 有权
标题翻译：注射装置
公开(公告)号：US20130138049A1
公开(公告)日：2013-05-30
申请号：US13581566
申请日：2011-03-03
申请人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Andrew Peter Scudamore , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20
CPC分类号： A61M5/322 , A61M5/2033 , A61M5/24 , A61M5/3202 , A61M5/3204 , A61M5/3234 , A61M5/326 , A61M2005/202 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2407 , A61M2005/2496 , A61M2005/3267
摘要： The invention relates to an injection device, comprising a syringe with a hollow needle and a stopper for sealing the syringe and displacing a medicament (M) stored in the syringe, the injection device further comprising a drive means, a plunger arranged for pushing against the stopper and an arrangement for transferring a translation of the drive means to the plunger, the arrangement comprising an elongate release latch member pivoted at one end which is connected to either the drive means or the plunger, the release latch member having another end for engaging the respective other one of the drive means or the plunger, wherein the release latch member is arranged to have its non-pivoted other end disengaged by rotation due to contact between at least one ramp and another component when the stopper has at least nearly displaced all of a predefined dose of the medicament (M), wherein a length of the release latch member is specified so as to provide a clearance between the plunger and the drive means when the release latch member is engaged in order to allow at least the plunger, the stopper and the hollow needle to be retracted at least far enough to hide the needle inside the syringe or inside a housing after disengaging the release latch member.
摘要翻译：本发明涉及一种注射装置，其包括具有中空针头的注射器和用于密封注射器并移动存储在注射器中的药物（M）的止动件，该注射装置还包括驱动装置，柱塞，止动器和用于将驱动装置的平移传递到柱塞的装置，该装置包括在连接到驱动装置或柱塞的一端枢转的细长释放闩锁构件，释放闩锁构件具有用于接合所述驱动装置或所述柱塞中的相应的另一个，其中所述释放闩锁构件被布置成使得当所述止动件至少几乎位移至少几乎全部时，所述释放闩锁构件由于至少一个斜坡和另一部件之间的接触而使其不可枢转的另一端由于旋转而脱离预定剂量的药物（M），其中指定释放闩锁构件的长度以便提供柱塞和当释放闩锁构件接合时，驱动装置是为了允许至少使柱塞，止动器和中空针缩回到至少足够远以在将释放闩锁构件分离之后将针隐藏在注射器内部或壳体内部。

7. 发明授权

US09457149B2 Back-end device for an auto-injector and auto-injector 有权
标题翻译：自动进样器和自动进样器的后端装置
公开(公告)号：US09457149B2
公开(公告)日：2016-10-04
申请号：US13996420
申请日：2011-12-21
申请人： Thomas Mark Kemp , Douglas Jennings , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Matthew Ekman
IPC分类号： A61M5/20 , A61M5/32 , A61M5/24 , A61M5/46
CPC分类号： A61M5/2033 , A61M5/20 , A61M5/24 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208 , A61M2005/2086
摘要： According to the invention, a back-end device of an auto-injector adapted to be attached to a packaged syringe comprises a plunger arranged to abut against a stopper of the packaged syringe to translate an injection needle of the packaged syringe in a proximal direction and to expel a dose of a medicament contained in the packaged syringe through the injection needle, a drive means capable of, upon release, driving the plunger in the proximal direction towards a proximal position, a rotary sleeve with a cam surface adapted to be engaged by a plunger follower formed to the plunger, a torsion spring arranged to exert a torque upon the rotary sleeve and a release element capable of, upon manual actuation, releasing the engagement of the plunger follower with the cam surface. The plunger follower is arranged to engage the cam surface to prevent the rotary sleeve from rotating with respect to the chassis in an initial state. Furthermore, in the initial state the plunger follower is arranged to engage the cam surface to prevent an axial translation of the plunger in the proximal direction. Upon release of the engagement of the plunger follower with the cam surface, the rotary sleeve is arranged to rotate within the chassis. The cam surface re-engages the plunger follower after a time delay determined by a rotation speed of the rotary sleeve. The time delay is set so as to allow the cam surface to re-engage the plunger follower after the plunger reaches the proximal position. The cam surface is arranged to withdraw the plunger from the proximal position in a distal direction by continued rotation of the rotary sleeve.

8. 发明申请

US20130267897A1 Back-End Device for an Auto-Injector and Auto-Injector 有权
标题翻译：自动进样器和自动进样器的后端装置
公开(公告)号：US20130267897A1
公开(公告)日：2013-10-10
申请号：US13996420
申请日：2011-12-21
申请人： Thomas Mark Kemp , Douglas Jennings , Matthew Ekman
发明人： Thomas Mark Kemp , Douglas Jennings , Matthew Ekman
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/20 , A61M5/24 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208 , A61M2005/2086
摘要： According to the invention, a back-end device of an auto-injector adapted to be attached to a packaged syringe comprises a plunger arranged to abut against a stopper of the packaged syringe to translate an injection needle of the packaged syringe in a proximal direction and to expel a dose of a medicament contained in the packaged syringe through the injection needle, a drive means capable of, upon release, driving the plunger in the proximal direction towards a proximal position, a rotary sleeve with a cam surface adapted to be engaged by a plunger follower formed to the plunger, a torsion spring arranged to exert a torque upon the rotary sleeve and a release element capable of, upon manual actuation, releasing the engagement of the plunger follower with the cam surface. The plunger follower is arranged to engage the cam surface to prevent the rotary sleeve from rotating with respect to the chassis in an initial state. Furthermore, in the initial state the plunger follower is arranged to engage the cam surface to prevent an axial translation of the plunger in the proximal direction. Upon release of the engagement of the plunger follower with the cam surface, the rotary sleeve is arranged to rotate within the chassis. The cam surface re-engages the plunger follower after a time delay determined by a rotation speed of the rotary sleeve. The time delay is set so as to allow the cam surface to re-engage the plunger follower after the plunger reaches the proximal position. The cam surface is arranged to withdraw the plunger from the proximal position in a distal direction by continued rotation of the rotary sleeve.
摘要翻译：根据本发明，适于附接到包装的注射器的自动注射器的后端装置包括柱塞，所述柱塞被布置成抵靠包装的注射器的塞子，以沿着近端方向平移包装的注射器的注射针，以通过所述注射针排出包装在所述包装注射器中的药物的剂量;驱动装置，其能够在释放时沿所述近端方向朝向近端位置驱动所述柱塞;旋转套筒，其具有适于被形成在柱塞上的柱塞随动件，设置成在旋转套筒上施加转矩的扭转弹簧和能够在手动致动时释放柱塞从动件与凸轮表面的接合的释放元件。柱塞从动件被布置成接合凸轮表面以防止旋转套筒在初始状态下相对于底盘旋转。此外，在初始状态下，柱塞从动件布置成接合凸轮表面以防止柱塞沿近端方向的轴向平移。当释放柱塞从动件与凸轮表面的接合时，旋转套筒被布置成在底盘内旋转。在由旋转套筒的旋转速度确定的时间延迟之后，凸轮表面重新接合柱塞从动件。时间延迟被设定为允许凸轮表面在柱塞到达近端位置之后重新接合柱塞从动件。凸轮表面布置成通过旋转套筒的持续旋转在远端方向上从近端位置缩回柱塞。

9. 发明授权

US09011387B2 Force transmission arrangement for auto-injector 有权
标题翻译：自动进样器的传动装置
公开(公告)号：US09011387B2
公开(公告)日：2015-04-21
申请号：US13580146
申请日：2011-02-16
申请人： Matthew Ekman , Timothy Donald Barrow-Williams , Thomas Mark Kemp
发明人： Matthew Ekman , Timothy Donald Barrow-Williams , Thomas Mark Kemp
IPC分类号： A61M5/20 , A61M5/32 , A61M5/315 , A61M5/46 , A61M5/48 , A61M5/24 , A61M5/31
CPC分类号： A61M5/3158 , A61M5/20 , A61M5/2033 , A61M5/315 , A61M5/3202 , A61M5/326 , A61M5/46 , A61M5/482 , A61M5/484 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2418 , A61M2005/3103 , A61M2005/3152 , A61M2005/3247 , A61M2205/581 , A61M2205/583
摘要： The invention relates to a transmission arrangement for controlling a force of a translation, the transmission arrangement comprising a drive collar (13) connectable to a translative drive means (11) and prevented from rotating with respect to a ground (12) of the drive means (11), a flange face of the drive collar (13) bearing against a mating flange face of a friction collar (20), the friction collar (20) slidable in longitudinal direction and rotationally constrained by engagement in a cam track (12.3), another flange face of the friction collar (20) bearing against a mating flange face of a plunger (8), the plunger (8) slidable in longitudinal direction and prevented from rotating.
摘要翻译：本发明涉及一种用于控制平移力的传动装置，该传动装置包括可连接到平移驱动装置（11）并被阻止相对于驱动装置（12）旋转的驱动套环（13）（11），所述驱动轴环（13）的凸缘面抵靠摩擦轴环（20）的配合凸缘面，所述摩擦轴环（20）可在纵向方向上滑动并通过接合在凸轮轨道（12.3）中而被旋转地限制，，所述摩擦轴环（20）的另一凸缘面抵靠着柱塞（8）的配合凸缘面，所述柱塞（8）可沿纵向方向滑动并防止旋转。

10. 发明授权

US08758304B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US08758304B2
公开(公告)日：2014-06-24
申请号：US13877160
申请日：2011-10-06
申请人： Thomas Mark Kemp , Matthew Ekman
发明人： Thomas Mark Kemp , Matthew Ekman
IPC分类号： A61M5/32
CPC分类号： A61M5/3287 , A61M5/2033 , A61M5/3202 , A61M5/326 , A61M2005/206 , A61M2005/208 , A61M2005/3247
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing, a syringe with a hollow needle and a bung for displacing the medicament, wherein the syringe is slidably arranged with respect to the housing, spring means for pushing the needle from a covered position inside the housing into an advanced position past the proximal end and for supplying the dose of medicament, activating means for locking and releasing the spring means. The spring means is a torsion spring grounded at one end in the housing and at the other end in a lead nut rotatable about a longitudinal axis but axially constrainable. The lead nut is arranged for translatively moving a piston rod by means of a lead screw thread. The piston rod is prevented from rotating relative to the housing and arranged to be coupled to the bung in order to push it forwards. The lead nut is engaged to the housing in an initial position prior to manual operation of the activating means in a manner to prevent rotation and disengaged from the housing by the activating means upon manual operation.The activating means is a trigger button, arranged at a distal end of the housing. Prior to manual operation the trigger button, the piston rod and the lead nut are coupled for joint translation in proximal direction. In the initial position the lead nut is engaged to the housing by at least one spline feature. The lead nut is arranged to disengage from the housing on translation in proximal direction from the initial position.
摘要翻译：本发明涉及一种用于给药液体药物的自动注射器，包括：细长壳体，具有中空针头的注射器和用于移动药物的栓塞，其中注射器相对于壳体可滑动地布置，弹簧用于将所述针从所述壳体内的覆盖位置推入超过所述近端的前进位置并用于供应所述剂量的药剂的启动装置，用于锁定和释放所述弹簧装置的启动装置。弹簧装置是扭转弹簧，其一端接合在壳体中，另一端处于可围绕纵向轴线旋转但可轴向限制的导螺母中。引导螺母布置成通过导螺纹来平移运动活塞杆。活塞杆被防止相对于壳体旋转并且被布置成联接到栓塞以向前推。在手动操作激活装置之前，引导螺母以初始位置接合到壳体，以防止在手动操作时由致动装置旋转和脱离外壳。激活装置是设置在壳体的远端处的触发按钮。在手动操作之前，触发按钮，活塞杆和引导螺母联接，以在近端方向进行联合平移。在初始位置，引导螺母通过至少一个花键特征与壳体接合。引导螺母布置成在近端方向上从初始位置平移脱离壳体。

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