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1. 发明申请

US20100209406A1 BACILLUS STRAINS AND METHODS FOR REDUCING E. COLI DISEASE AND ENHANCING PERFORMANCE 审中-公开
标题翻译：微生物菌株和减少大肠杆菌病和增强性能的方法
公开(公告)号：US20100209406A1
公开(公告)日：2010-08-19
申请号：US12573390
申请日：2009-10-05
申请人： Thomas G. Rehberger , Dorrie Sue Jordan-Parrott
发明人： Thomas G. Rehberger , Dorrie Sue Jordan-Parrott
IPC分类号： A61K35/74 , C12N1/20
CPC分类号： A61K35/742 , A23K10/18 , A23K50/30 , C12R1/07 , A61K2300/00
摘要： Bacillus strains that inhibit pathogenic swine E. coli and/or improve performance are provided. Inhibition of pathogenic swine E. coli decreases E. coli disease. At least one strain enhanced swine performance by improving average daily gain, feed efficiency, and feed intake. Preferred Bacillus strains are of species that are included on the GRAS list. Bacillus species are sporeformers and therefore are highly stable and can be fed to swine.
摘要翻译：提供了抑制致病性猪大肠杆菌和/或改善性能的芽孢杆菌菌株。致病性猪大肠杆菌的抑制减少大肠杆菌病。至少一种通过提高平均日增重，饲料效率和饲料摄入量来提高猪的表现。优选的芽孢杆菌菌株是GRAS列表中包含的物种。芽孢杆菌种是孢子形成物，因此是高度稳定的，可以喂给猪。

2. 发明授权

US07618640B2 Method and composition for reducing E. coli disease and enhancing performance 有权
标题翻译：减少大肠杆菌病的方法和组合，提高表现
公开(公告)号：US07618640B2
公开(公告)日：2009-11-17
申请号：US11129767
申请日：2005-05-13
申请人： Thomas G. Rehberger , Dorrie Sue Jordan-Parrott
发明人： Thomas G. Rehberger , Dorrie Sue Jordan-Parrott
IPC分类号： A61K39/02 , G01N33/53
CPC分类号： A61K35/742 , A23K10/18 , A23K50/30 , C12R1/07 , A61K2300/00
摘要： Bacillus strains that inhibit pathogenic swine E. coli and/or improve performance are provided. Inhibition of pathogenic swine E. coli decreases E. coli disease. At least one strain enhanced swine performance by improving average daily gain, feed efficiency, and feed intake. Preferred Bacillus strains are of species that are included on the GRAS list. Bacillus species are sporeformers and therefore are highly stable and can be fed to swine.
摘要翻译：提供了抑制致病性猪大肠杆菌和/或改善性能的芽孢杆菌菌株。致病性猪大肠杆菌的抑制减少大肠杆菌病。至少一种通过提高平均日增重，饲料效率和饲料摄入量来提高猪的表现。优选的芽孢杆菌菌株是GRAS列表中包含的物种。芽孢杆菌种是孢子形成物，因此是高度稳定的，可以喂给猪。

3. 发明申请

US20120315258A1 BACILLUS STRAINS AND METHODS FOR REDUCING E. COLI DISEASE AND ENHANCING PERFORMANCE 有权
标题翻译：微生物菌株和减少大肠杆菌病和增强性能的方法
公开(公告)号：US20120315258A1
公开(公告)日：2012-12-13
申请号：US13494468
申请日：2012-06-12
申请人： Thomas G. Rehberger , Dorrie Sue Jordan-Parrott
发明人： Thomas G. Rehberger , Dorrie Sue Jordan-Parrott
IPC分类号： A61K35/74 , A61P3/00
CPC分类号： A61K35/742 , A23K10/18 , A23K50/30 , C12R1/07 , A61K2300/00
摘要： Bacillus strains that inhibit pathogenic swine E. coli and/or improve performance are provided. Inhibition of pathogenic swine E. coli decreases E. coli disease. At least one strain enhanced swine performance by improving average daily gain, feed efficiency, and feed intake. Preferred Bacillus strains are of species that are included on the GRAS, i.e., generally recognized as safe, list. Bacillus species are sporeformers and therefore are highly stable and can be fed to swine.
摘要翻译：提供了抑制致病性猪大肠杆菌和/或改善性能的芽孢杆菌菌株。致病性猪大肠杆菌的抑制减少大肠杆菌病。至少一种通过提高平均日增重，饲料效率和饲料摄入量来提高猪的表现。优选的芽孢杆菌属菌株是包含在GRAS中的物种，即通常被认为是安全的。芽孢杆菌种是孢子形成物，因此是高度稳定的，可以喂给猪。

4. 发明申请

US20120063950A1 BACILLUS STRAINS USEFUL FOR ANIMAL ODOR CONTROL 有权
标题翻译：微生物菌株用于动物气味控制
公开(公告)号：US20120063950A1
公开(公告)日：2012-03-15
申请号：US13212424
申请日：2011-08-18
申请人： Marianne Cain Bellot , Keith J. Mertz , Thomas G. Rehberger
发明人： Marianne Cain Bellot , Keith J. Mertz , Thomas G. Rehberger
IPC分类号： A61L11/00
CPC分类号： A61L11/00 , A01K1/0152 , A01K1/0155 , C12N1/20 , C12R1/10 , C12R1/125
摘要： A composition is provided that includes Bacillus subtilis 2084 (NRRL B-50013) or a strain having all of the identifying characteristics of the Bacillus subtilis 2084 (NRRL B-50013), B. subtilis 27 (NRRL B-50105) or a strain having all of the identifying characteristics of the B. subtilis 27 (NRRL B-50105), and B. licheniformis 21 (NRRL B-50134) or a strain having all of the identifying characteristics of the B. licheniformis 21 (NRRL B-50134). Animal bedding that includes the Bacillus strains is also provided, as well as a method of making the animal bedding. Also provided are methods of controlling odors from animal waste. A method of making a composition including the Bacillus strains is also provided.
摘要翻译：提供了包含枯草芽孢杆菌2084（NRRL B-50013）或具有枯草芽孢杆菌2084（NRRL B-50013），枯草芽孢杆菌27（NRRL B-50105）的所有鉴定特征的菌株或具有枯草芽孢杆菌27（NRRL B-50105）和地衣芽孢杆菌21（NRRL B-50134）或具有地衣芽孢杆菌21（NRRL B-50134）的所有鉴定特征的菌株的所有鉴定特征。还提供了包括芽孢杆菌菌株的动物床上用品以及制作动物床上用品的方法。还提供了从动物废物中控制气味的方法。还提供了制备包含芽孢杆菌属菌株的组合物的方法。

5. 发明申请

US20080171102A1 METHODS OF MAKING AND USING LACTOBACILLUS STRAINS 有权
标题翻译：制备和使用乳杆菌菌株的方法
公开(公告)号：US20080171102A1
公开(公告)日：2008-07-17
申请号：US12055136
申请日：2008-03-25
申请人： Thomas G. Rehberger , Charles V. Maxwell
发明人： Thomas G. Rehberger , Charles V. Maxwell
IPC分类号： A23K1/00 , C12N1/20
CPC分类号： C12R1/225 , A23K10/18 , A23K50/00 , A23K50/30 , A23K50/60 , C12N1/20
摘要： Lactobacillus strains that have a genetic Profile I based on Apa I, Not I, and Xba I digests are provided. Preferably, the strains decrease level of at least one of coliforms and E. coli within the gastrointestinal tract of an animal. A direct-fed microbial that includes the strain is additionally provided. A method of feeding an animal the strain and a method of forming a direct fed microbial that includes the strain is also provided.
摘要翻译：提供了具有基于Apa I，Not I和Xba I消化物的遗传谱I的乳杆菌菌株。优选地，菌株在动物的胃肠道内降低大肠杆菌和大肠杆菌中的至少一种的水平。另外提供了包括该菌株的直接饲养的微生物。还提供了饲养动物的方法和形成包含该菌株的直接饲养的微生物的方法。

6. 发明授权

US07384628B2 Lactic acid bacteria and its use in direct-fed microbials 有权
标题翻译：乳酸菌及其在直接饲养微生物中的应用
公开(公告)号：US07384628B2
公开(公告)日：2008-06-10
申请号：US10874777
申请日：2004-06-23
申请人： Thomas G. Rehberger , Elizabeth A. Galbraith
发明人： Thomas G. Rehberger , Elizabeth A. Galbraith
IPC分类号： A23K97/04 , A23L1/28 , A23L1/31 , A01N63/00 , C12N1/02 , C12N1/20
CPC分类号： A61K35/747 , A23K10/18 , A23K50/60 , Y10S426/807 , Y10S435/855 , A61K2300/00
摘要： A composition comprising lactic acid bacteria that are selected from at least one of Lactococcus lactis, Lactobacillus lactis, and Lactobacillus brevis. The composition is suitable for administration to animals. Upon administration to an animal, the composition provides at least one of the following (a) improves performance in the animal and (b) reduces scours in animals. Also provided is a method of treating an animal in which the composition is administered to the animal. A method of forming a direct-fed microbial is also provided. A culture including the lactic acid bacteria is grown in a liquid nutrient broth. The lactic acid bacteria are separated from the liquid nutrient broth. The lactic acid bacteria can be freeze dried.
摘要翻译：一种组合物，其包含选自乳酸乳球菌，乳酸乳杆菌和短乳杆菌中的至少一种的乳酸菌。该组合物适用于给予动物。在给予动物时，组合物提供以下至少一种（a）改善动物的性能，和（b）减少动物的冲洗。还提供了一种治疗其中向动物施用组合物的动物的方法。还提供了形成直接进料的微生物的方法。包含乳酸菌的培养物在液体营养肉汤中生长。从液体营养液中分离乳酸菌。乳酸菌可以冷冻干燥。

7. 发明授权

US08557234B1 Methods of controlling pit foam 有权
标题翻译：控制泡沫泡沫的方法
公开(公告)号：US08557234B1
公开(公告)日：2013-10-15
申请号：US13110529
申请日：2011-05-18
申请人： Mari Ellen Davis , Terry D. Parrott , Joshua M. Rehberger , Thomas G. Rehberger , Ardean Veldkamp , Daniel Petri
发明人： Mari Ellen Davis , Terry D. Parrott , Joshua M. Rehberger , Thomas G. Rehberger , Ardean Veldkamp , Daniel Petri
IPC分类号： A01N63/00
CPC分类号： A01N63/00
摘要： A method of controlling foam in a manure pit. In the method, one or more Bacillus strain(s) is administered in an effective amount to animals whose manure is stored in the manure pit. Also provided is a method of controlling foam in a manure storage unit. In the method, one or more Bacillus strain(s) is administered in an effective amount to the manure storage unit.
摘要翻译：一种控制粪便中泡沫的方法。在该方法中，将一种或多种芽孢杆菌菌株以有效量施用于将粪便储存在粪便坑中的动物。还提供了一种控制粪便存储单元中的泡沫的方法。在该方法中，将一种或多种芽孢杆菌菌株以有效量施用于粪便储存单元。

8. 发明授权

US08404227B2 Bacillus strains useful for animal odor control 有权
公开(公告)号：US08404227B2
公开(公告)日：2013-03-26
申请号：US13212424
申请日：2011-08-18
申请人： Marianne Cain Bellot , Keith J. Mertz , Thomas G. Rehberger
发明人： Marianne Cain Bellot , Keith J. Mertz , Thomas G. Rehberger
IPC分类号： A01N63/00 , C12N1/20
CPC分类号： A61L11/00 , A01K1/0152 , A01K1/0155 , C12N1/20 , C12R1/10 , C12R1/125
摘要： A composition is provided that includes Bacillus subtilis 2084 (NRRL B-50013) or a strain having all of the identifying characteristics of the Bacillus subtilis 2084 (NRRL B-50013), B. subtilis 27 (NRRL B-50105) or a strain having all of the identifying characteristics of the B. subtilis 27 (NRRL B-50105), and B. licheniformis 21 (NRRL B-50134) or a strain having all of the identifying characteristics of the B. licheniformis 21 (NRRL B-50134). Animal bedding that includes the Bacillus strains is also provided, as well as a method of making the animal bedding. Also provided are methods of controlling odors from animal waste. A method of making a composition including the Bacillus strains is also provided.

9. 发明申请

US20120276058A1 METHANE REDUCING STRAINS AND METHODS OF USE 审中-公开
标题翻译：甲烷减少菌株及其使用方法
公开(公告)号：US20120276058A1
公开(公告)日：2012-11-01
申请号：US13456741
申请日：2012-04-26
申请人： Alexandra Helena Smith , Thomas G. Rehberger
发明人： Alexandra Helena Smith , Thomas G. Rehberger
IPC分类号： A61K35/74 , A61P3/00 , A61P1/14 , C12N1/20
CPC分类号： A23K50/10 , A23K10/16 , A23K10/18 , Y02P60/56
摘要： Strains and compositions of bacterium of the genus Propionibacterium are provided that reduce methane production in a ruminant animal. Strains and compositions can be used as a feed supplement. Also provided are methods for reducing methane production in a ruminant animal comprising the step of administering to the ruminant animal an effective amount of at least one strain of bacterium of the genus Propionibacterium.
摘要翻译：提供丙酸杆菌属细菌的菌株和组成，其可以减少反刍动物中的甲烷产生。菌株和组合物可用作饲料添加剂。还提供了用于降低反刍动物中甲烷产生的方法，包括向反刍动物施用有效量的至少一种丙酸杆菌属细菌菌株的步骤。

10. 发明授权

US08021655B2 Methods of feeding ruminants 有权
标题翻译：喂食反刍动物的方法
公开(公告)号：US08021655B2
公开(公告)日：2011-09-20
申请号：US12276007
申请日：2008-11-21
申请人： Thomas G. Rehberger , John P. O'Neill
发明人： Thomas G. Rehberger , John P. O'Neill
IPC分类号： A01N63/00
CPC分类号： C12R1/01 , A23K10/16 , A23K10/18 , A23K50/10 , C12N1/20
摘要： An isolated microorganism comprising a Propionibacteria strain is described. When the microorganism is fed to a ruminant, protein and fat levels in milk produced by the ruminant are increased, while body condition and milk production levels are maintained. When fed to the ruminant, the microorganism also has positive effects on various metabolic hormones and metabolites, e.g, an increase in energy balance, plasma non-esterified fatty acids levels, and plasma leptin level. Supplementation with propionibacteria reduced dry matter intake but did not affect milk production in the cows. Therefore, the propionibacteria of the invention made the cows more energy efficient as cows produced the same amount of milk, yet consumed less dry matter.
摘要翻译：描述了包含丙酸杆菌菌株的分离的微生物。当微生物饲喂反刍动物时，由反刍动物产生的乳汁中的蛋白质和脂肪水平增加，同时维持身体状况和产奶量。当喂养反刍动物时，微生物也对各种代谢激素和代谢物具有积极作用，例如能量平衡的增加，血浆未酯化的脂肪酸水平和血浆瘦素水平。补充丙酸杆菌减少干物质摄入量，但不影响奶牛的产奶量。因此，本发明的丙酸杆菌使得牛产生相同量的牛奶，同时消耗更少的干物质，使奶牛更节能。

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