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1. 发明授权

US4675641A Rating plug for molded case circuit breakers 失效
标题翻译：塑壳断路器额定插头
公开(公告)号：US4675641A
公开(公告)日：1987-06-23
申请号：US876499
申请日：1986-06-20
申请人： Thomas G. Hampton , James M. Mitsch , Joseph M. Palmieri , David S. Parker , James I. Smith
发明人： Thomas G. Hampton , James M. Mitsch , Joseph M. Palmieri , David S. Parker , James I. Smith
IPC分类号： H01H73/22 , H01H71/16 , H01H71/74 , H01H75/10
CPC分类号： H01H71/7409 , H01H2009/188 , H01H2069/016 , H01H2071/749 , H01H71/16
摘要： A selectable rating plug allows a standard molded case circuit breaker design to be used over a wide range of ampere ratings. The rating plug is used to control the thermal load on the thermally responsive trip element within the breaker. Movement of the thermally responsive element articulates the breaker trip mechanism in response to predetermined overload conditions to interrupt circuit current.
摘要翻译：可选择的额定插头允许在广泛的安培额定值范围内使用标准塑壳断路器设计。额定插头用于控制断路器内热响应跳闸元件的热负载。热响应元件的移动响应于预定的过载条件来断开断路器跳闸机构以中断电路电流。

2. 发明授权

US4706054A Thermal magnetic trip unit for molded case circuit breakers 失效
标题翻译：用于塑壳断路器的热磁脱扣器
公开(公告)号：US4706054A
公开(公告)日：1987-11-10
申请号：US907332
申请日：1986-09-15
申请人： Thomas G. Hampton , James M. Mitsch , Joseph M. Palmieri , David S. Parker , Donna C. DeRosier
发明人： Thomas G. Hampton , James M. Mitsch , Joseph M. Palmieri , David S. Parker , Donna C. DeRosier
IPC分类号： H01H71/40 , H01H9/00
CPC分类号： H01H71/405
摘要： A magnet piece and armature are arranged around a circuit breaker load strap having a bimetal strip attached thereto. The magnet piece is formed in a U-shaped configuration and is attached to the load strap. A corresponding U-shaped armature is pivotally mounted to the magnet piece in a partially overlapping relation. The U-shape armature presents a larger magnet pole surface to the magnet piece for enhanced magnetic interaction.
摘要翻译：磁体片和电枢围绕其上附着有双金属条的断路器负载带布置。磁体片形成为U形构造并且附接到负载带。相应的U形电枢以部分重叠的关系枢转地安装到磁体片上。 U形电枢对磁铁片呈现较大的磁极表面，以增强磁相互作用。

3. 发明授权

US06445941B1 Method and apparatus for non-invasively detecting, measuring, and recording electrocardiograms in conscious animals 有权
标题翻译：在有意识的动物中非侵入性地检测，测量和记录心电图的方法和装置
公开(公告)号：US06445941B1
公开(公告)日：2002-09-03
申请号：US09523770
申请日：2000-03-11
申请人： Thomas G. Hampton , Jose M. Otero
发明人： Thomas G. Hampton , Jose M. Otero
IPC分类号： A61B504
CPC分类号： A61B5/04085
摘要： A novel method and apparatus for obtaining the electrocardiogram (ECG) in small conscious animals, such as mice, without the need to anesthetize or instrument the animal, are described. The apparatus includes an array of conductive pads, embedded in a platform, the pads sized and spaced to advance contact between an animal's paws and the pads as the animal freely moves upon the platform. Electrical circuitry to the pads is configured to sense the parings of pads and paws that render an interpretable ECG signal and to activate or deactivate recording of the signals. The apparatus is suspended above a surface to minimize the range of motion of the animal without physical restraint. The method and apparatus of the present invention are intended to replace the use of anesthetics or invasive procedures to obtain ECGs in mice, to limit the range of motion of mice without physical restraint or harnessing, and to advance a common level of animal activity for animal-to-animal comparisons of cardiovascular function.
摘要翻译：描述了一种用于在小型有意识动物（例如小鼠）中获得心电图（ECG）的新方法和装置，而不需要麻醉或仪器仪器。该装置包括嵌入在平台中的导电垫片阵列，垫片的大小和间隔设置，以便随着动物在平台上自由移动而推动动物爪和垫之间的接触。焊盘的电路被配置为感测提供可解释的ECG信号并激活或停用信号记录的焊盘和爪的配对。该装置悬挂在表面上方以使动物的运动范围最小化，而不受身体限制。本发明的方法和装置旨在取代麻醉剂或侵入性方法在小鼠中获得ECG的用途，以限制小鼠的运动范围而不受身体限制或利用，并提高动物的动物活动的共同水平 - 动物比较心血管功能。

4. 发明申请

US20100047187A1 METHODS OF TREATING PARKINSON'S DISEASE USING HALOGENATED VOLATILE COMPOUNDS 有权
标题翻译：使用恶化挥发性化合物治疗帕金森病的方法
公开(公告)号：US20100047187A1
公开(公告)日：2010-02-25
申请号：US12530822
申请日：2008-03-17
申请人： Thomas G. Hampton
发明人： Thomas G. Hampton
IPC分类号： A61K9/12 , A61K31/08 , A61K33/00
CPC分类号： A61K31/02 , A61K31/075 , Y10S514/816
摘要： The present invention provides methods of using halogenated volatile compounds, e.g., halogenated ether, for treating a neurological disorder, e.g., Parkinson's disease.
摘要翻译：本发明提供了使用卤代挥发性化合物，例如卤代醚来治疗神经障碍例如帕金森病的方法。

5. 发明授权

US08222300B2 Methods of treating parkinson's disease using halogenated volatile compounds 有权
标题翻译：使用卤化挥发性化合物治疗帕金森病的方法
公开(公告)号：US08222300B2
公开(公告)日：2012-07-17
申请号：US12530822
申请日：2008-03-17
申请人： Thomas G. Hampton
发明人： Thomas G. Hampton
IPC分类号： A01N29/00 , A61K31/02
CPC分类号： A61K31/02 , A61K31/075 , Y10S514/816
摘要： The present invention provides methods of using halogenated volatile compounds, e.g., halogenated ether, for treating a neurological disorder, e.g., Parkinson's disease.
摘要翻译：本发明提供了使用卤代挥发性化合物，例如卤代醚来治疗神经障碍例如帕金森病的方法。

6. 发明授权

US06875418B2 Method of early detection of Duchenne muscular dystrophy and other neuromuscular disease 有权
标题翻译：早期发现杜氏肌营养不良症及其他神经肌肉疾病的方法
公开(公告)号：US06875418B2
公开(公告)日：2005-04-05
申请号：US10175691
申请日：2002-06-19
申请人： Thomas G. Hampton
发明人： Thomas G. Hampton
IPC分类号： A61K49/00 , A61B5/00
CPC分类号： A61K49/0004 , A61B5/4035
摘要： The mdx mouse is a model of Duchenne muscular dystrophy. The present invention describes that mdx mice exhibited clinically relevant cardiac phenotypes. A non-invasive method of recording electrocardiograms (ECGs) was used to a study mdx mice (n=15) and control mice (n=15). The mdx mice had significant tachycardia, consistent with observations in patients with muscular dystrophy. Heart-rate was nearly 15% faster in mdx mice than control mice (P
摘要翻译： mdx小鼠是Duchenne肌营养不良症的模型。本发明描述了mdx小鼠表现出临床相关的心脏表型。记录心电图（ECG）的非侵入性方法用于研究mdx小鼠（n = 15）和对照小鼠（n = 15）。 mdx小鼠具有显着的心动过速，与肌营养不良患者的观察结果一致。 mdx小鼠的心率比对照组高出近15％（P <0.01）。与对照小鼠相比，心电图显示mdx小鼠中速率校正的QT间期持续时间（QTc）显着缩短（P <0.05）。与对照小鼠相比，mdx基线时PR间期持续时间更短（P <0.05）。毒蕈碱拮抗剂阿托品在C57小鼠中显着增加心率和减少PR间期持续时间。矛盾的是，阿托品在所有mdx小鼠中显着降低心率和增加PR间期持续时间。药理学自主性阻断和压力反射敏感性检测显示，心肌率的自主神经系统调节失调，mdx小鼠副交感神经活动减少，交感神经活动增强。肌营养不良蛋白缺陷型小鼠的这些心电图发现为诊断，理解和治疗杜氏肌营养不良患者提供了新的基础。

7. 发明授权

US08694086B2 Systems and methods for non-invasively recording ECG in conscious ambulatory subjects 有权
标题翻译：在意识动员科目中非侵入式记录心电图的系统和方法
公开(公告)号：US08694086B2
公开(公告)日：2014-04-08
申请号：US13359071
申请日：2012-01-26
申请人： Thomas G. Hampton
发明人： Thomas G. Hampton
IPC分类号： A61B5/0402 , A61B5/0432
CPC分类号： A61B5/0408 , A61B5/6888
摘要： An apparatus for non-invasively measuring an electrocardiogram (ECG) in a conscious ambulatory subject includes an electrically conductive platform. The electrically conductive platform establishes an electrical connection with the subject at one of a position forward (e.g., rostral to) or a position rearward (e.g., caudal to) the heart. An additional electrical connection is established at the other of a position forward (e.g., rostral to) or a position rearward (e.g., caudal to) on the subject. The position rearward to (e.g., caudal to) the heart can be the tail of the subject. The additional electrical connection can be established by a movable electrode, an electrically conductive ringlet, an additional electrically conductive platform, a region of conductive material, an electrically conductive dome, a food element, or one or more electrically conductive posts.
摘要翻译：用于非侵入式测量有意识的行走主体中的心电图（ECG）的装置包括导电平台。导电平台在向前（例如，朝向或向后）位置（例如，尾部到达心脏）的位置之一处建立与受试者的电连接。在对象的前方（例如，向前）或向后（例如，尾部）的位置的另一个处建立另外的电连接。心脏向后的（例如，尾部）的位置可以是受试者的尾巴。附加的电连接可以通过可移动电极，导电小环，附加导电平台，导电材料区域，导电圆顶，食物元件或一个或多个导电柱来建立。

8. 发明授权

US07065396B2 System and method for non-invasive monitoring of physiological parameters 有权
公开(公告)号：US07065396B2
公开(公告)日：2006-06-20
申请号：US10209103
申请日：2002-07-30
申请人： Thomas G. Hampton
发明人： Thomas G. Hampton
IPC分类号： A61B5/04
CPC分类号： A61B5/0006 , A61B5/0408
摘要： A method and apparatus for enabling the non-invasive acquisition of physiological parameters of a mammal, while allowing the mammal to move around a predetermined area is provided. In accordance with one example embodiment, a monitoring device for non-invasively acquiring physiological measurements of a mammal is provided. The device includes a first electrode configured to attach to an ear of the mammal in a manner suitable for obtaining a first electrical signal. A second electrode is configured to attach to a first alternate location of the mammal in a manner suitable for obtaining a second electrical signal. A third electrode is configured to attach to a second alternate location of the mammal in a manner suitable for obtaining a third electrical signal. The first electrode, second electrode, and third electrode are in communication with a signal receiver. Physiological parameters, such as those associated with electrocardiograms, can be obtained using the monitoring device.

9. 发明授权

US06899686B2 Method and apparatus for monitoring locomotion kinematics in ambulating animals 有权
标题翻译：监测动物体动运动学的方法和装置
公开(公告)号：US06899686B2
公开(公告)日：2005-05-31
申请号：US10245480
申请日：2002-09-17
申请人： Thomas G. Hampton , José Manuel Otero , Stephanie Praster
发明人： Thomas G. Hampton , José Manuel Otero , Stephanie Praster
IPC分类号： A61B5/103 , A61B5/117
CPC分类号： A61B5/1038 , A01K1/031 , A61H2203/03 , G06F19/00
摘要： A method and apparatus for recording and analyzing the gait of an animal is provided. The apparatus can take the form of a gait imaging system. The system includes a movable belt track upon which a subject can ambulate. An imaging device is disposed below the belt track to record contact between at least one limb of the subject and the belt track. The subject can ambulate along the belt track in a substantially stationary location above the imaging device as the belt track moves, and the imaging device can record the contact by the subject. A method of recording a gait of an ambulating subject is also provided. The method includes locating the subject on a movable belt track. The subject is motivated to ambulate along the movable belt track at about the same rate as the movable belt track, while the belt track is moving, such that the location of the subject does not substantially change. Contact made by at least one limb of the subject with the belt track is recorded with a recording device underneath the belt track. Additional kinematic analysis can occur of the subject's gait. The method of recording can further include transmission of the gait images to a computing apparatus. The computing apparatus can identify footprint image data, including filtering out unwanted noise. The computing apparatus can then carry out the kinematic analysis, including calculation of physiological information relating to the subject.
摘要翻译：提供了用于记录和分析动物的步态的方法和装置。该装置可以采取步态成像系统的形式。该系统包括可移动的带轨道，受试者可以在其上行走。成像装置设置在皮带轨道下方，以记录被检体的至少一个肢体和皮带轨道之间的接触。当皮带轨道移动时，被摄体可以在成像装置上方的基本静止的位置沿着皮带轨迹行进，并且成像装置可以记录受试者的接触。还提供了记录步行对象的步态的方法。该方法包括将物体定位在可移动带轨道上。受试者被激励以与可移动带轨道大致相同的速率沿着可移动带轨道行进，同时皮带轨道移动，使得被摄体的位置基本上不变化。由带轨道的至少一个肢体进行的接触记录在皮带轨道下面的记录装置。可以对受试者的步态进行额外的运动学分析。记录方法还可以包括将步态图像发送到计算装置。计算设备可以识别占用图像数据，包括滤除不想要的噪声。计算装置然后可以执行运动学分析，包括计算与被摄体有关的生理信息。

10. 发明申请

US20120190995A1 SYSTEMS AND METHODS FOR NON-INVASIVELY RECORDING ECG IN CONSCIOUS AMBULATORY SUBJECTS 有权
标题翻译：无意识记录心电图在系统和方法中的应用
公开(公告)号：US20120190995A1
公开(公告)日：2012-07-26
申请号：US13359071
申请日：2012-01-26
申请人： Thomas G. Hampton
发明人： Thomas G. Hampton
IPC分类号： A61B5/0432 , A61B5/0408
CPC分类号： A61B5/0408 , A61B5/6888
摘要： An apparatus for non-invasively measuring an electrocardiogram (ECG) in a conscious ambulatory subject includes an electrically conductive platform. The electrically conductive platform establishes an electrical connection with the subject at one of a position forward (e.g., rostral to) or a position rearward (e.g., caudal to) the heart. An additional electrical connection is established at the other of a position forward (e.g., rostral to) or a position rearward (e.g., caudal to) on the subject. The position rearward to (e.g., caudal to) the heart can be the tail of the subject. The additional electrical connection can be established by a movable electrode, an electrically conductive ringlet, an additional electrically conductive platform, a region of conductive material, an electrically conductive dome, a food element, or one or more electrically conductive posts.
摘要翻译：用于非侵入式测量有意识的行走主体中的心电图（ECG）的装置包括导电平台。导电平台在向前（例如，朝向或向后）位置（例如，尾部到达心脏）的位置之一处建立与受试者的电连接。在对象的前方（例如，向前）或向后（例如，尾部）的位置的另一个处建立另外的电连接。心脏向后的（例如，尾部）的位置可以是受试者的尾巴。附加的电连接可以通过可移动电极，导电小环，附加导电平台，导电材料区域，导电圆顶，食物元件或一个或多个导电柱来建立。

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