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    • 1. 发明申请
    • Ligational encoding of small molecules
    • 小分子的编码编码
    • US20060246450A1
    • 2006-11-02
    • US10549619
    • 2004-03-22
    • Thomas FranchSoeren JacobsenTorben RasmussenSoeren NeveHenrik PedersenAlex Gouliaev
    • Thomas FranchSoeren JacobsenTorben RasmussenSoeren NeveHenrik PedersenAlex Gouliaev
    • C12Q1/68C07H21/04C12P19/34
    • C07H21/04C12N15/1068C12P21/02C40B40/06C40B50/04
    • The invention relates to a method for synthesising a bifunctional complex comprising an encoded molecule and an identifier polynucleotide identifying the chemical entities having participated in the synthesis of the encoded molecule, said method comprising the steps of i) providing a) at least one template comprising one or more codons capable of hybridising to an anti-codon, wherein said template is optionally associated with one or more chemical entities, and b) a plurality of building blocks each comprising an anti-codon associated with one or more chemical entities, and ii) hybridising the anti-codon of one or more of the provided building blocks to the template, iii) covalently linking said anti-codons and/or linking the at least one template with the anti-codon of at least one building block, thereby generating an identifier polynucleotide capable of identifying chemical entities having participated in the synthesis of the encoded molecule, iv) separating the template from one or more of the anti-codons hybridised thereto, thereby generating an at least partly single stranded identifier polynucleotide associated with a plurality of chemical entities, v) generating a bifunctional complex comprising an encoded molecule and an identifier polynucleotide identifying the chemical entities having participated in the synthesis of the encoded molecule, wherein said encoded molecule is generated by reacting at least two of said plurality of chemical entities associated with the identifier polynucleotide, and wherein said at least two chemical entities are provided by separate building blocks.
    • 本发明涉及一种合成双功能复合物的方法,所述双功能复合物包含编码分子和识别已经参与编码分子合成的化学实体的标识多核苷酸,所述方法包括以下步骤:i)提供a)至少一个包含一个 或更多能够与抗密码子杂交的密码子,其中所述模板任选地与一个或多个化学实体相关联,以及b)多个结构单元,每个结构单元包含与一个或多个化学实体相关的抗密码子,以及ii) 将一个或多个所提供的构建块的抗密码子与模板杂交,iii)共价连接所述抗密码子和/或将至少一个模板与至少一个构建块的抗密码子连接,由此产生 能够识别已经参与编码分子的合成的化学实体的标识符多核苷酸,iv)将模板从一个或多个分离出来 更多的与其杂交的抗密码子,从而产生与多个化学实体相关联的至少部分单链标识多核苷酸,v)产生包含编码分子的双功能复合物和识别参与合成的化学实体的标识符多核苷酸 的编码分子,其中所述编码的分子通过使与所述标识多核苷酸相关联的所述多个化学实体中的至少两个反应而产生,并且其中所述至少两个化学实体由单独的构建块提供。
    • 3. 发明申请
    • CIGARETTE HOLDER FOR SMOKE DILUTION
    • 香烟喷雾器用于吸烟
    • US20110247639A1
    • 2011-10-13
    • US13129748
    • 2009-11-24
    • Torben Rasmussen
    • Torben Rasmussen
    • A24F47/00
    • A24F13/04
    • There is provided a smoke mouthpiece (1) for the dilution of smoke from a smoking element, such as a cigarette (11), to an exhaust region (7), comprising an internal longitudinal channel with openings at both ends and divided into 5 channel sections, wherein a first channel section (2) is provided in the first end of the smoking mouthpiece (1) with an opening for insertion of the smoking element (11), where a second channel section (3) for holding the smoking element (11) is in axial extension of the first channel section (2) with a smaller cross-section than the first channel section (2), where a third channel section (4) is in axial extension of the second channel section (3) to stop the end of the cigarette, where a fourth channel section (5) for diluting the smoke of the smoking element is in axial extension of the third channel section (4), where a fifth channel section (6) is provided at the other end of the smoking mouthpiece (1) in axial extension of the fourth channel section (5), wherein one or more air channels (8), (8′), (8″) are provided in the one or more channel sections for diluting the smoke of the smoking element with atmospheric air, said air channel(s) (8), (8′), (8″) ensure passage of atmospheric air from the first channel section (2) to the fourth channel section (5) when the smoking element (11) is in place in the second channel section.
    • 提供了一种用于将吸烟元件如香烟(11)的烟气稀释到排气区域(7)的烟嘴(1),其包括在两端具有开口并分成5个通道的内部纵向通道 其中第一通道部分(2)设置在吸嘴(1)的第一端,具有用于插入吸烟元件(11)的开口,其中用于保持吸烟元件的第二通道部分(3) 11)以比第一通道部分(2)更小的横截面在第一通道部分(2)的轴向延伸中,其中第三通道部分(4)在第二通道部分(3)的轴向延伸到 停止香烟的端部,其中用于稀释吸烟元件的烟雾的第四通道部分(5)处于第三通道部分(4)的轴向延伸部分,在另一端设置有第五通道部分(6) 的吸嘴(1)在第四通道部分的轴向延伸 (5),其中一个或多个空气通道(8),(8'),(8“)设置在所述一个或多个通道部分中,用于用大气空气稀释所述吸烟元件的烟雾, (8),(8'),(8“)确保当吸烟元件(11)在第二通道部分中就位时,大气从第一通道部分(2)到第四通道部分(5)的通过。
    • 4. 发明授权
    • Interchangeable different printing technologies modules for a web
printing assembly
    • 可互换的不同的印刷技术模块,用于卷筒纸印刷组件
    • US5697297A
    • 1997-12-16
    • US696926
    • 1996-08-16
    • Torben Rasmussen
    • Torben Rasmussen
    • B41F11/00B41F13/00B41F13/44B41F19/06B41F5/04
    • B41F19/062B41F11/00B41F13/0024B41F13/44B41P2217/11B41P2219/51
    • A highly flexible printing apparatus is provided comprising printing modules (A-F) and cassettes (8) containing different web processing means. Each of the cassettes (8) is adapted to be mounted on a selected printing module (A-F) to cooperate with the module (A-F) during production of printed matters and contains means for a specific web processing technology that will be provided by the selected printing module (A-F) when the cassette (8) has been mounted to it. The different cassettes (8) may contain web processing means of a great variety, such as offset printing means, dry offset printing means, letterpress printing means, serigraphy means, hot foil application means, flexographic means, raised printing means, punching means, means for printing electronically generated images, etc. With the new printing apparatus provided, a printing house will be able to produce printed matters in one single working process on a single printing apparatus as an operator of the printing apparatus is free to configurate the printing apparatus with web processing technologies in a desired order as needed for production of a specific printed matter. For example a cassette (8) intended for offset printing may contain a plate cylinder (9) and a blanket cylinder (10). When mounted on the printing module (A-F) these cylinders cooperate with the impression cylinder (5), the ink roller system (7), the moisture roller system (7), and the other means of the printing module (A-F) to do offset printing.
    • PCT No.PCT / DK95 / 00175 Sec。 371日期:1996年8月16日 102(e)日期1996年8月16日PCT提交1995年4月26日PCT公布。 第WO95 / 29813号公报 日期:1995年11月9日提供了一种高灵活性的打印装置,其包括包含不同纸幅处理装置的打印模块(A-F)和纸盒(8)。 每个盒(8)适于安装在所选择的打印模块(AF)上,以在印刷品的生产期间与模块(AF)配合,并且包含用于通过所选择的打印提供的特定卷筒纸处理技术的装置 当盒(8)已经安装到其上时,模块(AF)。 不同的盒(8)可以包含各种纸幅处理装置,例如胶版印刷装置,干胶版印刷装置,凸版印刷装置,印刷装置,热箔涂布装置,柔版印刷装置,凸起印刷装置,冲孔装置 用于印刷电子产生的图像等。在提供新的印刷设备的情况下,打印机将能够在单个印刷设备的一个单一工作过程中生产印刷品,因为印刷设备的操作者可以自由地配置印刷设备 网页处理技术按照特定印刷品生产所需的顺序进行。 例如,用于胶印的盒(8)可以包含印版滚筒(9)和橡皮滚筒(10)。 当安装在打印模块(AF)上时,这些气缸与压印滚筒(5),墨辊系统(7),湿气辊系统(7)以及打印模块(AF)的其他装置配合来进行偏移 打印。
    • 6. 发明授权
    • Modular moulding tools for use in a machine for manufacturing shells or
thin-walled blanks from pulp material
    • 用于从纸浆材料制造壳体或薄壁坯料的机器中的模块化模制工具
    • US06149772A
    • 2000-11-21
    • US227823
    • 1999-01-11
    • Torben Rasmussen
    • Torben Rasmussen
    • B29C41/38D21J5/00D21J7/00D21J3/00
    • D21J7/00D21J5/00
    • The mutually associated moulding tools, such as a suction mould and an associated pressing-and-depositing mould, neither of which are shown, comprise a baseplate (1) with a modularly divided, rectangular area (2) provided with perforations (3), on which area (2) it is possible to secure, e.g. by means of screws, a number of closely adjacent modular mould parts (A,B) with a rectangular outline, each of the modular mould parts (A,B) serving to produce an article (C,D,E) to be separated from the pulp-material shell having been produced in a subsequent operation. With this arrangement, it is possible to keep the cost of manufacturing the moulding tools and the time required for re-arranging them at such low levels, that even small series of articles (C,D,E) may be manufactured profitably.
    • 相互关联的模制工具,例如抽吸模具和相关联的压力和沉积模具,其中都未示出,其包括具有模块化划分的矩形区域(2)的基板(1),其具有穿孔(3), 在哪个区域(2)可以固定,例如 通过螺钉,多个紧密相邻的具有矩形轮廓的模块化模具部件(A,B),每个模块化模具部件(A,B)用于生产待分离的制品(C,D,E) 纸浆材料壳已经在随后的操作中生产。 通过这种布置,可以将制造成型工具的成本和将其重新布置所需的时间保持在如此低的水平,即使可以有利地制造小系列的制品(C,D,E)。
    • 7. 发明授权
    • Method for processing a continuous web extending along a predetermined
path
    • 用于处理沿预定路径延伸的连续卷材的方法
    • US5711225A
    • 1998-01-27
    • US687536
    • 1996-07-30
    • Torben Rasmussen
    • Torben Rasmussen
    • B41F13/04B41F13/54
    • B41F13/04B41P2217/52
    • A method and a cylinder arrangement for a printing apparatus is provided in which printing plates (16,17) or punching plates (16,17) of different lengths may selectively be mounted on the same plate cylinder (12,13), and wherein a web (10) to be printed or punched may be moved past the cylinder (12,13) at a substantially constant speed. Two or more formats (18,19) may be interlaced on the web (10). The formats (18, 19) may be of different lenghts in the longitudinal direction of the web (10). Adjustment means for adjusting web length between printing units or between contact points between the web (10) and plates (16,17) within the same printing unit are not needed.
    • PCT No.PCT / DK95 / 00043 Sec。 371日期:1996年7月30日 102(e)日期1996年7月30日PCT提交1995年1月30日PCT公布。 第WO95 / 20488号公报 日期1995年8月3日提供了一种用于打印设备的方法和气缸装置,其中可以选择性地将不同长度的印版(16,17)或冲压板(16,17)安装在同一印版滚筒(12,13)上 ),并且其中要打印或冲压的卷材(10)可以以基本恒定的速度移动经过滚筒(12,13)。 两个或多个格式(18,19)可以在网(10)上交错。 格式(18,19)在幅材(10)的纵向上可以具有不同的长度。 不需要用于调节印刷单元之间的幅材长度或在同一印刷单元内的幅材(10)和板(16,17)之间的接触点之间的调节装置。