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1. 发明申请

US20100069767A1 SYSTEM AND METHOD FOR ANALYZING COMPLEX CURVATURE OF ECG CURVES 有权
标题翻译：用于分析ECG曲线复合曲线的系统和方法
公开(公告)号：US20100069767A1
公开(公告)日：2010-03-18
申请号：US12517120
申请日：2007-11-28
申请人： Thomas Bork Hardahl , Claus Graff , Mads Peter Andersen , Egon Toft , Johannes Jan Struijk , Joel Q. Xue
发明人： Thomas Bork Hardahl , Claus Graff , Mads Peter Andersen , Egon Toft , Johannes Jan Struijk , Joel Q. Xue
IPC分类号： A61B5/0402
CPC分类号： A61B5/0452 , A61B5/7239 , G06K9/0053
摘要： The present invention relates to a system and a method for analysis of ECG curvature, which system involves a mathematical analysis, which analysis comprises the following features where a number of different parameters are isolated and stored in computer means, where a first number of parameters are selected from at least one main group, where the selected parameters are combined in at least a first mathematical analysis. It is the object of the invention to improve mathematical analysis of ECG curvature particular for complex parts of the curvature such as notches or concavities. It is a further object of the invention to improve automatic quantification of symmetry, flatness and durations of ECG curvature. This can be achieved if the parameters are selected from groups of symmetry, flatness, duration and/or complexity, which parameters are used as input to an algorithm, where concavity intervals are evaluated on subsegments of the ECG segment and form the basis of up- and downwards concavity quantification, where the system based on an algorithm detects and quantifies concavity on ECG curvatures. Herby can be achieved that a complex curvature can be analysed and the complex curvature might indicate symptoms of diseases which are very difficult to read on ECG curvature by existing technology. This can lead to a more precise analysis where existing systems might by analysing the curvature give a first indication of a symptom. By then performing an analysis of the complex part of the curvature, further symptoms might be indicated.
摘要翻译：本发明涉及一种用于分析ECG曲率的系统和方法，该系统涉及数学分析，该分析包括以下特征，其中许多不同参数被隔离并存储在计算机装置中，其中第一数量的参数是从至少一个主组中选择，其中所选参数在至少第一数学分析中组合。本发明的目的是改进对曲率复杂部分（例如凹口或凹陷）特别的ECG曲率的数学分析。本发明的另一个目的是提高ECG曲率的对称性，平坦度和持续时间的自动量化。如果从对称组，平面度，持续时间和/或复杂度组中选择参数，则可以实现这些参数，哪些参数被用作算法的输入，其中在ECG分段的子段上评估凹陷间隔，并且向下凹陷量化，其中基于算法的系统检测和量化ECG曲率上的凹度。可以实现Herby，可以分析复杂的曲率，复杂曲率可能表明现有技术在ECG曲率上难以读取的疾病症状。这可以导致更精确的分析，其中现有系统可能通过分析曲率给出症状的第一指示。然后对曲率的复杂部分进行分析，可能会显示进一步的症状。

2. 发明授权

US08260406B2 System and method for analyzing complex curvature of ECG curves 有权
标题翻译：用于分析ECG曲线复曲率的系统和方法
公开(公告)号：US08260406B2
公开(公告)日：2012-09-04
申请号：US12517120
申请日：2007-11-28
申请人： Thomas Bork Hardahl , Claus Graff , Mads Peter Andersen , Egon Toft , Johannes Jan Struijk , Joel Q. Xue
发明人： Thomas Bork Hardahl , Claus Graff , Mads Peter Andersen , Egon Toft , Johannes Jan Struijk , Joel Q. Xue
IPC分类号： A61B5/04
CPC分类号： A61B5/0452 , A61B5/7239 , G06K9/0053
摘要： A system and a method for analysis of ECG curvature, which system involves a mathematical analysis comprising the following features where a number of different parameters are isolated and stored in a computer, where a first number of parameters are selected from at least one main group, where the selected parameters are combined in at least a first mathematical analysis. It is the object of the invention to improve mathematical analysis of ECG curvature particular for complex parts of the curvature such as notches or concavities. This can be achieved by selecting parameters from groups of symmetry, flatness, duration and/or complexity, using the parameters as input to an algorithm, where concavity intervals are evaluated on subsegments of the ECG segment and form the basis of up and downwards concavity quantification, where the system based on an algorithm detects and quantifies concavity on ECG curvatures.
摘要翻译：一种用于分析ECG曲率的系统和方法，该系统包括数学分析，其包括以下特征，其中将多个不同参数隔离并存储在计算机中，其中从至少一个主组中选择第一数量的参数，其中所选参数在至少第一数学分析中组合。本发明的目的是改进对曲率复杂部分（例如凹口或凹陷）特别的ECG曲率的数学分析。这可以通过使用参数作为算法的输入来选择对称组，平坦度，持续时间和/或复杂度的参数来实现，其中在ECG片段的子段上评估凹陷间隔并形成上下凹凸量化的基础，其中基于算法的系统检测并量化ECG曲率上的凹度。

3. 发明授权

US08229551B2 Method of presenting electrocardiographic data 有权
标题翻译：呈现心电图数据的方法
公开(公告)号：US08229551B2
公开(公告)日：2012-07-24
申请号：US12624925
申请日：2009-11-24
申请人： Joel Q. Xue
发明人： Joel Q. Xue
IPC分类号： A61B5/0402
CPC分类号： A61B5/044 , A61B5/0452 , G06F19/00
摘要： A system and method of presenting physiological data in a component ring. The method includes receiving a plurality of leads of physiological data. Morphology features are extracted from the plurality of leads. The morphology features are graphed by presenting a component ring associated with each of the morphology features. The system includes at least two sensors configured to collect physiological data. A processor is configured to extract amplitudes of morphology features. A graphical user interface is configured to graphically display the morphology features in a plurality of component rings.
摘要翻译：在组件环中呈现生理数据的系统和方法。该方法包括接收生理数据的多个引线。从多个引线提取形态特征。通过呈现与每个形态特征相关联的分量环来绘制形态特征。该系统包括至少两个被配置成收集生理数据的传感器。处理器被配置为提取形态特征的振幅。图形用户界面被配置为以图形方式显示多个组件环中的形态特征。

4. 发明授权

US07702382B2 Multi-tier system for cardiology and patient monitoring data analysis 有权
标题翻译：多层系统用于心脏病学和病人监测数据分析
公开(公告)号：US07702382B2
公开(公告)日：2010-04-20
申请号：US11405151
申请日：2006-04-17
申请人： Joel Q. Xue , G. Ian Rowlandson
发明人： Joel Q. Xue , G. Ian Rowlandson
IPC分类号： A61B5/02
CPC分类号： A61B5/0452 , A61B5/0006 , G06F19/00 , G16H10/20
摘要： In a multi-tier patient monitoring data analysis system, an algorithm server is positioned as a middle tier between an acquisition device, such as a cardiograph or patient monitor that can be seen as a lower tier, and a storage device for a database, such as that of a central computer for a hospital or clinic that can be seen as an upper tier. The algorithm server gathers current data from the real time acquisition device and obtains previously stored ECG signal data from the database. The algorithm server contains ECG analysis algorithm(s) and runs one or more algorithms using the current and previously acquired ECG signal data. Analysis algorithms may also be run on the acquisition device. The system provides the rapid, extensive, and thorough ECG analysis that is critical to patient welfare.
摘要翻译：在多级患者监测数据分析系统中，算法服务器被定位为可以被视为较低层的采集设备（例如心电图仪或患者监护仪）和数据库的存储设备之间的中间层，例如像医院或诊所的中央计算机，可以看作是上层。算法服务器从实时采集设备收集当前数据，并从数据库获取以前存储的ECG信号数据。算法服务器包含ECG分析算法，并使用当前和之前获取的ECG信号数据运行一个或多个算法。分析算法也可以在采集设备上运行。该系统提供对患者福利至关重要的快速，广泛和彻底的心电图分析。

5. 发明申请

US20090228298A1 SYSTEM AND METHOD OF MORPHOLOGY FEATURE ANALYSIS OF PHYSIOLOGICAL DATA 审中-公开
标题翻译：生理数据的形态学特征分析系统与方法
公开(公告)号：US20090228298A1
公开(公告)日：2009-09-10
申请号：US12042192
申请日：2008-03-04
申请人： Joel Q. Xue
发明人： Joel Q. Xue
IPC分类号： G06Q50/00
CPC分类号： A61B5/0452 , A61B5/0456 , A61B5/0472 , G06K9/00536 , G06K9/6263 , G06Q50/22
摘要： A system and method of analyzing physiological data morphology includes a first physiological data source. A morphological segment detection module receives first physiological data from the first physiological data source and applies at least one algorithm to identify at least one morphological segment of the first physiological data. A segment feature rating module applies at least one algorithm to the at least one identified morphological segment to identify at least one segment feature to produce rating of the severity of the at least one segment feature.
摘要翻译：分析生理数据形态的系统和方法包括第一生理数据源。形态段检测模块从第一生理数据源接收第一生理数据，并应用至少一个算法来识别第一生理数据的至少一个形态段。段特征评估模块将至少一个算法应用于所述至少一个识别的形态段以识别至少一个段特征以产生所述至少一个段特征的严重性的等级。

6. 发明申请

US20080082015A1 PRE-CONDITIONED ECG SYSTEM AND METHOD 审中-公开
标题翻译：预调心电图系统和方法
公开(公告)号：US20080082015A1
公开(公告)日：2008-04-03
申请号：US11538343
申请日：2006-10-03
申请人： Mark Kohls , Gordon Ian Rowlandson , Joel Q. Xue
发明人： Mark Kohls , Gordon Ian Rowlandson , Joel Q. Xue
IPC分类号： A61B5/04
CPC分类号： A61B5/0452 , A61B5/0456 , A61B2560/0276
摘要： A pre-conditioned ECG system and method includes a patient signaling device configured to alert the patient to minimize the patient's activity so that an ECG measurement may be taken, and further alerts the patient when the measurement is completed. The pre-conditioned ECG system and method also includes a pre-set buffer configured to hold a preset length of ECG data, and further configured to hold pre-set ECG parameters such as mean R-R interval, standard deviation of R-R interval, or simple rhythm analysis. The system and method may analyze the current 10 seconds of ECG data when the preset parameters are met or when selected parameters are met.
摘要翻译：预调节心电图系统和方法包括患者信号装置，其被配置为警告患者以最小化患者的活动，使得可以进行ECG测量，并且当测量完成时进一步警告患者。所述预处理ECG系统和方法还包括预置缓冲器，其被配置为保持预设长度的ECG数据，并且还被配置为保持预设的ECG参数，例如平均RR间隔，RR间期的标准偏差或简单节奏分析。当满足预设参数或满足选择的参数时，系统和方法可以分析当前10秒的ECG数据。

7. 发明申请

US20080082013A1 METHOD AND APPARATUS WITH REDUCED ELECTRODE SYSTEM SPECIFIC ECG INTERPRETATION 有权
标题翻译：具有减少电极系统特异性ECG解释的方法和装置
公开(公告)号：US20080082013A1
公开(公告)日：2008-04-03
申请号：US11536716
申请日：2006-09-29
申请人： Joel Q. Xue , Donald E. Brodnick
发明人： Joel Q. Xue , Donald E. Brodnick
IPC分类号： A61B5/04
CPC分类号： A61B5/0452
摘要： A method and apparatus for processing electrocardiographic signals of a patient. The apparatus comprises ten or fewer electrodes connected to a patient at at least one of the standard twelve lead ECG electrode positions. The apparatus further comprises a plurality of ECG interpretation algorithms, each of the algorithms specifically tailored for analyzing a twelve lead ECG comprising both measured and derived ECG leads. The method of the present invention comprises determining whether an ECG lead is measured or derived and selecting an ECG interpretation algorithm based upon this determination.
摘要翻译：一种用于处理患者的心电图信号的方法和装置。该装置包括在标准十二个导联ECG电极位置中的至少一个上连接到患者的十个或更少的电极。该装置还包括多个ECG解释算法，每个算法专门用于分析包括测量和导出的ECG导联的十二个导联ECG。本发明的方法包括确定是否测量或导出ECG导联，并且基于该确定选择ECG解释算法。

8. 发明申请

US20120030255A1 SYSTEMS AND METHODS FOR MODELING ELECTRICAL ACTIVITY OF AN ANATOMICAL STRUCTURE 有权
标题翻译：用于建立解剖结构电活动的系统和方法
公开(公告)号：US20120030255A1
公开(公告)日：2012-02-02
申请号：US13255136
申请日：2009-04-20
申请人： Joel Q. Xue , Weihua Gao , Yao Chen , Xiaodong Han
发明人： Joel Q. Xue , Weihua Gao , Yao Chen , Xiaodong Han
IPC分类号： G06F17/30
CPC分类号： A61B5/04012 , A61B5/044 , G06F19/00 , G16H50/50
摘要： A system for modeling electrical activity of an anatomical structure. The system includes a database that is configured to store cell set data corresponding to a group of cells of the anatomical structure. The cell set data includes a cell model that represents electrical activity of the group of cells. The cell model has a model parameter that relates to ion channels in the cells. The electrical activity represented by the cell model is at least partially based upon the model parameter. The system also includes a user interface that is configured to accept user inputs to change the model parameter and thereby change the electrical activity represented by the cell model to form a reconfigured cell model. The system also includes a display that is configured to display the user inputs and a processor that is configured to determine the electrical activity of the anatomical structure using the reconfigured cell model.
摘要翻译：用于建模解剖结构的电活动的系统。该系统包括被配置为存储与解剖结构的一组细胞相对应的细胞组数据的数据库。细胞组数据包括表示细胞组的电活动的细胞模型。细胞模型具有与细胞中的离子通道相关的模型参数。由细胞模型表示的电活动至少部分地基于模型参数。该系统还包括被配置为接受用户输入以改变模型参数并由此改变由小区模型表示的电活动以形成重新配置的小区模型的用户界面。该系统还包括被配置为显示用户输入的显示器和被配置为使用重新配置的单元模型来确定解剖结构的电活动的处理器。

9. 发明授权

US07813792B2 Method and apparatus for analyzing and editing ECG morphology and time series 有权
标题翻译：用于分析和编辑心电图形态学和时间序列的方法和装置
公开(公告)号：US07813792B2
公开(公告)日：2010-10-12
申请号：US11405150
申请日：2006-04-17
申请人： Joel Q. Xue , Paul P. Elko
发明人： Joel Q. Xue , Paul P. Elko
IPC分类号： A61B5/044 , A61B5/0464 , A61B5/046
CPC分类号： A61B5/0452
摘要： A method and apparatus for analyzing the QT interval characteristics of ECG signal data having a succession of waveforms produced by the beating of the heart. ECG signal data is obtained from a patient. The R-R interval and the QT intervals of the waveforms of the ECG signal data are determined. Waveforms of the ECG signal data having a stable heart rate are selected for use in determining the QT interval characteristics. Preferably, the waveforms selected are those having minimum R-R interval standard deviation and minimum R-R interval dispersion. The QT correction (QTc) is computed from the ECG signal data waveforms selected in the foregoing manner or on the basis of clinician editing. The R-R intervals, the QT intervals, and QTc for the heart beats of the selected waveforms are displayed for analysis and diagnosis purposes. The invention can also be used, in an analogous manner, to obtain and display other cardiac data from the ECG waveforms.
摘要翻译：一种用于分析具有通过心脏跳动产生的一系列波形的ECG信号数据的QT间期特征的方法和装置。从患者获得ECG信号数据。确定ECG信号数据的波形的R-R间隔和QT间隔。选择具有稳定心率的ECG信号数据的波形用于确定QT间期特征。优选地，所选择的波形是具有最小R-R间隔标准偏差和最小R-R间隔色散的波形。根据以上述方式选择的ECG信号数据波形或基于临床医师的编辑来计算QT校正（QTc）。显示所选波形的心跳的R-R间隔，QT间隔和QTc用于分析和诊断目的。本发明也可以以类似的方式用于从ECG波形获得和显示其他心脏数据。

10. 发明授权

US09603539B2 Systems and methods for modeling electrical activity of an anatomical structure 有权
公开(公告)号：US09603539B2
公开(公告)日：2017-03-28
申请号：US13255136
申请日：2009-04-20
申请人： Joel Q. Xue , Weihua Gao , Yao Chen , Xiaodong Han
发明人： Joel Q. Xue , Weihua Gao , Yao Chen , Xiaodong Han
IPC分类号： G06F19/00 , A61B5/0468 , A61B5/00 , A61B5/04 , A61H31/00 , A61B5/044
CPC分类号： A61B5/04012 , A61B5/044 , G06F19/00 , G16H50/50
摘要： A system for modeling electrical activity of an anatomical structure. The system includes a database that is configured to store cell set data corresponding to a group of cells of the anatomical structure. The cell set data includes a cell model that represents electrical activity of the group of cells. The cell model has a model parameter that relates to ion channels in the cells. The electrical activity represented by the cell model is at least partially based upon the model parameter. The system also includes a user interface that is configured to accept user inputs to change the model parameter and thereby change the electrical activity represented by the cell model to form a reconfigured cell model. The system also includes a display that is configured to display the user inputs and a processor that is configured to determine the electrical activity of the anatomical structure using the reconfigured cell model.

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