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    • 3. 发明申请
    • TISSUE PROCESSING APPARATUS WITH FLUID SUCTION FEATURES AND METHODS RELATING TO COLLECTING AND PROCESSING HUMAN BIOLOGICAL MATERIAL
    • 具有流体吸收特征的组织加工装置和与收集和加工人体生物材料相关的方法
    • US20160008407A1
    • 2016-01-14
    • US14863007
    • 2015-09-23
    • The GID Group, Inc.
    • William W. CiminoAdam J. KatzRamon Llull
    • A61K35/35A61K45/06A61K35/12A61M1/00C12N5/077
    • A61K35/12A61K35/35A61K45/06A61M1/0001A61M1/0094A61M2202/08A61M2205/75C12M27/02C12M45/09C12N5/0653
    • A portable apparatus for collection and processing of human biological material containing adipose, such as extracted during a lipoplasty procedure, is useful for multi-step processing to prepare a concentrated product (e.g., stromal vascular fraction) or a fat graft composition. The apparatus has a container with an internal containment volume with a tissue retention volume and a filtrate volume separated by a filter and with a tapered portion to a collection volume for collecting concentrate product. The apparatus has fluid suction features including a suction port and a conduit providing fluid communication from the suction port to a location within the filtrate volume within a tapered portion of the internal containment volume, and optionally including a second suction port and a second conduit to a different location in the filtrate volume with the second conduit being configured to permit elevation adjustment within the filtrate volume. Methods include use of the fluid suction features during collection of human biological material and/or post collection.
    • 用于收集和加工含有脂肪的人体生物材料的便携式装置,例如在脂肪成形术过程中提取的,可用于多步骤加工以制备浓缩产物(例如基质血管部分)或脂肪移植组合物。 该装置具有容器,其具有内部容纳体积,其具有组织保持体积,并且由过滤器分离出的滤液体积,并具有锥形部分,用于收集浓缩物产品的收集容积。 该装置具有流体抽吸特征,包括吸入口和导管,其提供从吸入口到内部容纳体积的锥形部分内的滤液体积内的位置的流体连通,并且可选地包括第二吸入口和第二管道 滤液体积中的不同位置,第二导管被配置为允许滤液体积内的高度调节。 方法包括在人体生物材料收集和/或收集后采用流体抽吸特征。
    • 4. 发明授权
    • Tissue processing apparatus and method for processing adipose tissue
    • 用于处理脂肪组织的组织处理装置和方法
    • US09296984B2
    • 2016-03-29
    • US14403861
    • 2013-09-05
    • THE GID GROUP, INC.
    • William W. CiminoRamon LlullAdam J. Katz
    • C12M1/33C12M1/00
    • C12M45/02C12M47/04C12N5/0653C12N2509/10
    • A portable apparatus useful for collection and processing of human biological material containing adipose, such as extracted during a lipoplasty procedure to prepare a concentrated product (e.g., stromal vascular fraction) or a fat graft composition. The apparatus has a container with a containment volume with a tissue retention volume and a filtrate volume separated by a filter and with a tapered portion to a collection volume for collecting concentrate product. Inlet and suction ports provide access to the tissue retention volume and filtrate volume, respectively, and an extraction port provides versatile access for removal of target processed concentrate material or fat graft material, which access may be via a lumen through a rotatable mixer shaft. Access ports may be configured for access only from above the container. The apparatus may include a tissue collector disposed in the disuse retention volume to engage and collect collagen or other stringy tissue. A method of processing adipose tissue to concentrate leuko stromal vascular cells includes multi-step processing using a portable container.
    • 一种用于收集和加工含有脂肪的人类生物材料的便携式装置,例如在脂肪成形术过程中提取以制备浓缩产物(例如基质血管部分)或脂肪移植组合物。 该装置具有容器,其具有容纳体积,具有组织保持体积,滤液体积由过滤器分离,并具有锥形部分,用于收集浓缩物产品的收集容积。 入口和吸入口分别提供对组织保持体积和滤液体积的访问,并且提取端口提供用于去除目标处理的浓缩物质或脂肪移植材料的通用途径,其可通过可旋转的混合器轴通过管腔进入。 访问端口可以被配置为仅从容器上方访问。 该装置可以包括设置在废弃保留体积中的组织收集器,以接合和收集胶原蛋白或其它丝状组织。 处理脂肪组织以浓缩白细胞基质血管细胞的方法包括使用便携式容器的多步骤处理。
    • 5. 发明申请
    • METHOD AND APPARATUS FOR PROCESSING ADIPOSE TISSUE
    • 用于加工ADIPOSE组织的方法和装置
    • US20140363891A1
    • 2014-12-11
    • US14370694
    • 2013-01-11
    • THE GID GROUP, INC.
    • Ramon LlullAdam J. KatzWilliam W. Cimino
    • C12N5/077
    • A61K35/12A61K35/35A61K45/06A61M1/0001A61M1/0094A61M2202/08A61M2205/75C12M27/02C12M45/09C12N5/0653
    • A portable apparatus for collection and processing of human biological material, such as containing adipose extracted during a lipoplasty procedure, is useful for multi-step processing to prepare a concentrated product (e.g., stromal vascular fraction) or a fat graft composition. The apparatus has a container with a containment volume with a tissue retention volume and a filtrate volume separated by a filter and with a tapered portion to a collection volume for collecting concentrate product. Inlet and suction ports provide access to the tissue retention volume and filtrate volume, respectively, and an extraction port provides versatile access for removal of target processed concentrate material or fat graft material, which access may be via a lumen through a rotatable mixer shaft. Access ports may be configured for access only from above the container. A method of processing adipose tissue to concentrate leuko stromal vascular cells includes multi-step processing using a portable container.
    • 用于收集和处理人类生物材料的便携式装置,例如在脂肪成形术过程中提取的含脂肪,可用于制备浓缩产物(例如基质血管部分)或脂肪移植组合物的多步骤加工。 该装置具有容器,其具有容纳体积,具有组织保持体积,滤液体积由过滤器分离,并具有锥形部分,用于收集浓缩物产品的收集容积。 入口和吸入口分别提供对组织保持体积和滤液体积的访问,并且提取端口提供用于去除目标处理的浓缩物质或脂肪移植材料的通用途径,其可通过可旋转的混合器轴通过管腔进入。 访问端口可以被配置为仅从容器上方访问。 处理脂肪组织以浓缩白细胞基质血管细胞的方法包括使用便携式容器的多步骤处理。
    • 7. 发明申请
    • TISSUE PROCESSING APPARATUS WITH FILTER PIERCEABLE TO REMOVE PRODUCT AND METHOD FOR PROCESSING ADIPOSE TISSUE
    • 具有可移除产品的过滤器的组织加工设备和用于加工ADIPOSE组织的方法
    • US20150368603A1
    • 2015-12-24
    • US14839650
    • 2015-08-28
    • The GID Group, Inc.
    • William W. CiminoAdam J. KatzRamon Llull
    • C12M1/26C12M1/00
    • C12M33/04A61L27/227A61L27/3683A61L27/3834B01D29/6476C12M33/14C12M47/00C12M47/04
    • A portable apparatus for collection and processing of human biological material, such as containing adipose extracted during a lipoplasty procedure, is useful for multi-step processing to prepare a concentrated product (e.g., stromal vascular fraction). The apparatus has a container with a containment volume with a tissue retention volume and a filtrate volume separated by a filter and with a tapered portion to a collection volume for collecting concentrate product. Inlet and suction ports provide access to the tissue retention volume and filtrate volume, respectively, and an extraction port provides versatile access for removal of target processed concentrate material. Advancing a hollow member such as a hypodermic needle through the extraction port and into the collection volume pierces the filter with the hollow member, providing a safety feature to prevent reuse of the apparatus. Access ports may be configured for access only from above the container. A method of processing adipose tissue to concentrate stromal vascular cells includes multi-step processing using a portable container.
    • 用于收集和处理人类生物材料的便携式装置,例如在脂肪成形术过程中提取的含脂肪,可用于制备浓缩产物(例如基质血管部分)的多步骤加工。 该装置具有容器,其具有容纳体积,具有组织保持体积,滤液体积由过滤器分离,并具有锥形部分,用于收集浓缩物产品的收集容积。 入口和抽吸口分别提供对组织保留体积和滤液体积的访问,并且提取端口提供了用于去除目标处理的浓缩物质的通用途径。 通过提取口推进诸如皮下注射针的中空构件并进入收集容积中用中空构件刺穿过滤器,从而提供安全特征以防止再次使用该装置。 访问端口可以被配置为仅从容器上方访问。 加工脂肪组织以浓缩基质血管细胞的方法包括使用便携式容器的多步骤处理。
    • 8. 发明申请
    • TISSUE PROCESSING APPARATUS WITH MIXING DEVICE AND METHOD FOR PROCESSING ADIPOSE TISSUE
    • 具有混合装置的组织加工装置和用于加工ADIPOSE组织的方法
    • US20150352256A1
    • 2015-12-10
    • US14832773
    • 2015-08-21
    • The GID Group, Inc.
    • William W. CiminoAdam J. KatzRamon Llull
    • A61L27/36A61L27/38A61L27/22B01D29/64
    • C12M33/04A61L27/227A61L27/3683A61L27/3834B01D29/6476C12M33/14C12M47/00C12M47/04
    • A portable apparatus for collection and processing of human biological material, such as containing adipose extracted during a lipoplasty procedure, is useful for multi-step processing to prepare a concentrated product (e.g., stromal vascular fraction) or a fat graft composition. The apparatus has a container with a containment volume with a tissue retention volume and a filtrate volume separated by a filter and with a tapered portion to a collection volume for collecting concentrate product. The apparatus includes a mixing device disposed at least in part within the tissue retention volume, and wherein the mixing device has a rotatable shaft extending from outside of to inside of the internal containment volume and has at least one mixing member that is disposed in the tissue retention volume with at least a portion disposed in the tapered portion of the internal containment volume and that is connected with the shaft to move through the tissue retention volume when the shaft is rotated.
    • 用于收集和处理人类生物材料的便携式装置,例如在脂肪成形术过程中提取的含脂肪,可用于制备浓缩产物(例如基质血管部分)或脂肪移植组合物的多步骤加工。 该装置具有容器,其具有容纳体积,具有组织保持体积,滤液体积由过滤器分离,并具有锥形部分,用于收集浓缩物产品的收集容积。 所述装置包括至少部分地设置在所述组织保持容积内的混合装置,并且其中所述混合装置具有从所述内部容纳容积的内部的内部延伸的可旋转的轴,并且具有设置在所述组织中的至少一个混合构件 保持体积,其至少一部分设置在内部容纳体积的锥形部分中,并且当轴旋转时与轴连接以移动通过组织保持体积。