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    • 8. 发明申请
    • IMPLANTS AND METHODS FOR RESHAPING HEART VALVES
    • 用于修复心脏瓣膜的植入物和方法
    • US20110257741A1
    • 2011-10-20
    • US13088189
    • 2011-04-15
    • Shahram MoaddebEmanuel ShaoulianSamuel M. ShaolianMichael R. HensonRichard S. RheeSteven C. Anderson
    • Shahram MoaddebEmanuel ShaoulianSamuel M. ShaolianMichael R. HensonRichard S. RheeSteven C. Anderson
    • A61F2/24
    • A61F2/2442A61B17/3468A61B2017/00243A61F2/2451A61F2002/249A61F2210/0076
    • Tissue shaping methods and devices are provided for reinforcing and/or remodeling heart valves. In certain embodiments, magnetic tissue shaping devices are implanted in tissue adjacent heart valve leaflets. The devices are mutually attractive or repulsive so as to remodel the heart tissue and improve heart valve function. In certain other embodiments, one or more tissue shaping devices including shape memory material are implanted in a patient's body within or on tissue adjacent a heart valve leaflet. The shape memory material can be activated within the patient in a less invasive or non-invasive manner, such as by applying energy percutaneously or external to the patient's body. The shape memory tissue shaping devices are implanted in a first configuration and then activated to remember a second configuration that displaces tissue so as to remodel the heart valve geometry and improve heart valve function. In certain other embodiments, a brace is crimped to the base of a heart valve leaflet to support the leaflet and improve valve closure.
    • 提供组织成形方法和装置用于加强和/或改造心脏瓣膜。 在某些实施例中,将磁组织成形装置植入在心脏瓣膜小叶附近的组织中。 这些装置是相互吸引或排斥的,以便改造心脏组织并改善心脏瓣膜功能。 在某些其他实施例中,包括形状记忆材料的一个或多个组织成形装置植入在心脏瓣膜附近的组织内或组织附近的患者体内。 形状记忆材料可以以较少侵入性或非侵入性方式在患者体内被激活,例如通过经皮或外部施加能量到患者身体。 形状记忆组织成形装置以第一配置植入,然后被激活以记住置换组织的第二配置,以便改造心脏瓣膜几何形状并改善心脏瓣膜功能。 在某些其他实施例中,支架卷曲到心脏瓣膜小叶的底部以支撑小叶并改善瓣膜关闭。
    • 9. 发明申请
    • Dynamically adjustable vascular stent
    • 动态调节血管支架
    • US20080004692A1
    • 2008-01-03
    • US11477152
    • 2006-06-28
    • Michael R. HensonShahram MoaddebSamuel M. Shaolian
    • Michael R. HensonShahram MoaddebSamuel M. Shaolian
    • A61F2/06
    • A61F2/88A61B17/12022A61B17/12118A61B2017/00867A61B2017/1205A61F2002/30098A61F2002/301A61F2210/0033A61F2210/0038
    • Methods and devices are provided for providing a protective framework for treating an aneurysm with embolic coils and preventing mitigation of the embolic coils from the aneurysm. A dynamically remodelable stent having a first and a second configuration is delivered into the blood vessel patient, such as a human or other animal, and positioned adjacent an ostium of an aneurysm while in the first, linear configuration. The dynamically remodelable stent may then be activated to assume a second, expanded configuration and thereby provide a protective framework spanning the neck of the aneurysm during and after delivery of embolic devices, such as embolic coils, to the aneurysm. The stent can be activated within the body of a patient in a minimally invasive or non-invasive manner such as by applying energy percutaneously or external to the patient's body. The energy may include, for example, acoustic energy, radio frequency energy, light energy and magnetic energy. In certain embodiments, the stent include a shape memory material that is responsive to changes in temperature and/or exposure to a magnetic field.
    • 提供了用于提供用于治疗具有栓塞线圈的动脉瘤的保护框架并且防止来自动脉瘤的栓塞线圈的方法和装置。 具有第一和第二构型的动态可重塑支架被递送到诸如人或其他动物的血管患者中,并且在第一线性构型中位于动脉瘤的口附近。 动态可重塑支架然后可以被激活以呈现第二扩张构型,从而在栓塞装置(例如栓塞线圈)输送到动脉瘤期间和之后提供横跨动脉瘤颈部的保护框架。 支架可以以微创或非侵入性方式在患者体内激活,例如通过经皮或外部施加能量到患者身体。 能量可以包括例如声能,射频能量,光能和磁能。 在某些实施例中,支架包括响应温度变化和/或暴露于磁场的形状记忆材料。
    • 10. 发明授权
    • Thrombectomy system and method
    • 血栓切除系统及方法
    • US08343167B2
    • 2013-01-01
    • US12187227
    • 2008-08-06
    • Michael R. Henson
    • Michael R. Henson
    • A61B17/22
    • A61B17/221A61B2017/00867A61B2017/22034A61B2017/2217
    • Disclosed is a clot and foreign body removal system, including a catheter with at least one lumen. Located within the catheter is a clot capture wire that is connected to a hub at the proximal end. In one embodiment, the clot capture wire includes a coil made out of an elastic or superelastic material, preferably nitinol. The elasticity or superelasticity of the coil allows it to be deformed within the catheter and to then reform its original coil configuration when the coil is moved outside of the catheter lumen. In another embodiment the coil is a biphasic, shape memory coil, which changes shape upon heating, energy application, or passing an electric current. Once the coil configuration has been established, the coil can be used to ensnare and corkscrew a clot or blockage in a vessel. A clot is extracted from the vessel by moving the clot capture coil and catheter proximally until the clot can be removed completely or released into a different vessel that does not perfuse a critical organ. Foreign bodies are similarly captured by deploying the coil distal to the foreign body and moving the clot capture coil proximally until the foreign body is trapped within the coil. By removing the device from the body, the foreign material is also removed.
    • 公开了一种血块和异物去除系统,包括具有至少一个内腔的导管。 位于导管内的是在近端连接到轮毂的血块捕获线。 在一个实施方案中,凝块捕获线包括由弹性或超弹性材料制成的线圈,优选镍钛诺。 线圈的弹性或超弹性允许其在导管内变形,然后当线圈移动到导管腔体外部时改变其原始线圈构型。 在另一个实施例中,线圈是双相形状记忆线圈,其在加热,能量施加或通过电流时改变形状。 一旦建立了线圈配置,线圈就可以用于在容器内锁住和开瓶凝块或堵塞。 通过将凝块捕获线圈和导管向近端移动直到凝块可以完全去除或释放到不灌注关键器官的不同容器中,从血管中提取凝块。 类似地通过将线圈远离外来部署线圈并将血块捕获线圈向近侧移动,直到异物被捕获在线圈内,类似地捕获异物。 通过从体内取出装置,也会去除异物。