专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20100028973A1 METHOD FOR PROLIFERATING HEPATITIS VIRUS, HOLLOW FIBER FOR CULTURING HEPATITIS VIRUS-INFECTED CELLS, AND USE THEREOF 审中-公开
标题翻译：用于增殖乙型肝炎病毒的方法，用于培养乙型肝炎病毒感染细胞的中空纤维及其用途
公开(公告)号：US20100028973A1
公开(公告)日：2010-02-04
申请号：US12442695
申请日：2007-09-26
申请人： Tatsuya Yamaguchi , Masaya Segawa , Masashi Mizokami , Yasuhito Tanaka , Kunitada Shimotohno , Makoto Hijikata
发明人： Tatsuya Yamaguchi , Masaya Segawa , Masashi Mizokami , Yasuhito Tanaka , Kunitada Shimotohno , Makoto Hijikata
IPC分类号： C12N7/00
CPC分类号： C12Q1/045 , C12N7/00 , C12N2730/10151 , C12N2730/10152 , C12N2770/24251 , C12N2770/24252 , C12Q1/025
摘要： The present invention provides (i) a method for proliferating a hepatitis virus, the method including the steps of: infecting, with the hepatitis virus, cells packed into a lumen of a hollow fiber made of a permeabilized membrane; and culturing the cells or (ii) a method for proliferating a hepatitis virus, the method including the steps of: infecting cells with the hepatitis virus; packing the cells into a lumen of a hollow fiber made of a permeabilized membrane; and culturing the cells. This provides an experimental system for infecting in vitro culture cells with a hepatitis virus such as HBV or HCV and then proliferating the hepatitis virus.
摘要翻译：本发明提供（i）一种增加肝炎病毒的方法，其特征在于，包括以下步骤：用肝炎病毒感染填充在由透化膜构成的中空纤维的内腔中的细胞; 和（ii）增殖型肝炎病毒的方法，所述方法包括以下步骤：用所述肝炎病毒感染细胞; 将细胞包装到由透化膜制成的中空纤维的内腔中; 并培养细胞。这提供了用肝炎病毒如HBV或HCV感染体外培养细胞，然后增殖肝炎病毒的实验系统。

2. 发明授权

US07968518B2 Use of modified cyclosporins for the treatment of HCV disorders 有权
标题翻译：使用改良的环孢菌素治疗HCV疾病
公开(公告)号：US07968518B2
公开(公告)日：2011-06-28
申请号：US10570097
申请日：2004-09-02
申请人： Makoto Hijikata , Kunitada Shimotohno , Koichi Watashi
发明人： Makoto Hijikata , Kunitada Shimotohno , Koichi Watashi
IPC分类号： A61K38/12 , A61K39/29 , A61K38/13
CPC分类号： A61K38/13
摘要： Disclosed are non-immunosuppressive cyclophilin-binding cyclosporins, e.g., of formula (I, Ia or II) as defined herein, having useful properties in the prevention of Hepatitis C infections.
摘要翻译：披露了非免疫抑制亲环蛋白结合的环孢菌素，例如本文定义的式（I，Ia或II），具有预防丙型肝炎感染的有用性质。

3. 发明申请

US20070275884A1 Use of modified cyclosporins for the treatment of hcv disorders 有权
标题翻译：使用改性环孢菌素治疗hcv疾病
公开(公告)号：US20070275884A1
公开(公告)日：2007-11-29
申请号：US10570097
申请日：2004-09-02
申请人： Makoto Hijikata , Kunitada Shimotohno , Koichi Watashi
发明人： Makoto Hijikata , Kunitada Shimotohno , Koichi Watashi
IPC分类号： A61K38/13
CPC分类号： A61K38/13
摘要： Disclosed are non-immunosuppressive cyclophilin-binding cyclosporins, e.g. of formula (I, Ia or II) as defined herein, having useful properties in the prevention or treatment of Hepatitis C infections.
摘要翻译：公开了非免疫抑制性亲环蛋白结合环孢菌素，例如的式（I，Ia或II），其具有预防或治疗丙型肝炎感染的有用性质。

4. 发明申请

US20140030809A1 METHOD FOR PRODUCING EPITHELIAL STEM CELLS 有权
标题翻译：用于生产上皮干细胞的方法
公开(公告)号：US20140030809A1
公开(公告)日：2014-01-30
申请号：US14007133
申请日：2012-03-23
申请人： Makoto Hijikata , Hassan Hussein Aly , Tatsuya Yamaguchi
发明人： Makoto Hijikata , Hassan Hussein Aly , Tatsuya Yamaguchi
IPC分类号： C12N5/071
CPC分类号： C12N5/0672 , A61K35/36 , C07K2319/43 , C12N5/067 , C12N9/12 , C12N2500/90 , C12N2501/119 , C12N2501/12 , C12N2501/155 , C12N2501/405 , C12N2510/00 , C12N2533/30 , C12N2533/54 , C12Y207/11022
摘要： An object of this invention is to provide a method, etc., for efficiently proliferating a pluripotent epithelial somatic stem cell. A method for producing an epithelial somatic stem cell comprising Steps (A) and (B) below: (A) expressing a gene of a protein having an activity for causing a cell in G0 phase or G1 phase to enter S phase, in a cell population including an epithelial somatic stem cell; and (B) culturing the cell obtained in Step (A) in the presence of an extracellular growth factor.
摘要翻译：本发明的目的是提供一种用于有效增殖多能上皮体细胞干细胞的方法等。一种上皮体细胞干细胞的制造方法，其特征在于，包括以下步骤（A）和（B）：（A）在细胞中表达具有使G0期或G1期细胞进入S期的活性的蛋白质的基因人群包括上皮体细胞干细胞; 和（B）在细胞外生长因子的存在下培养步骤（A）中获得的细胞。

5. 发明授权

US09249394B2 Method for producing epithelial stem cells 有权
标题翻译：产生上皮干细胞的方法
公开(公告)号：US09249394B2
公开(公告)日：2016-02-02
申请号：US14007133
申请日：2012-03-23
申请人： Makoto Hijikata , Hassan Hussein Aly , Tatsuya Yamaguchi
发明人： Makoto Hijikata , Hassan Hussein Aly , Tatsuya Yamaguchi
IPC分类号： C12N5/00 , C12N5/071 , C12N9/12 , A61K35/36
CPC分类号： C12N5/0672 , A61K35/36 , C07K2319/43 , C12N5/067 , C12N9/12 , C12N2500/90 , C12N2501/119 , C12N2501/12 , C12N2501/155 , C12N2501/405 , C12N2510/00 , C12N2533/30 , C12N2533/54 , C12Y207/11022
摘要： An object of this invention is to provide a method, etc., for efficiently proliferating a pluripotent epithelial somatic stem cell. A method for producing an epithelial somatic stem cell comprising Steps (A) and (B) below: (A) expressing a gene of a protein having an activity for causing a cell in G0 phase or G1 phase to enter S phase, in a cell population including an epithelial somatic stem cell; and (B) culturing the cell obtained in Step (A) in the presence of an extracellular growth factor.
摘要翻译：本发明的目的是提供一种用于有效增殖多能上皮体细胞干细胞的方法等。一种上皮体细胞干细胞的制造方法，其特征在于，包括以下步骤（A）和（B）：（A）在细胞中表达具有使G0期或G1期细胞进入S期的活性的蛋白质的基因人群包括上皮体细胞干细胞; 和（B）在细胞外生长因子的存在下培养步骤（A）中获得的细胞。

6. 发明授权

US06510385B2 Navigation apparatus, navigation method, and information recording medium in which program for navigation is computer-readably recorded 失效
标题翻译：导航装置，导航方法和信息记录介质，其中用于导航的程序被计算机可读地记录
公开(公告)号：US06510385B2
公开(公告)日：2003-01-21
申请号：US10012457
申请日：2001-12-12
申请人： Makoto Hijikata
发明人： Makoto Hijikata
IPC分类号： G01C2130
CPC分类号： G01C21/3415
摘要： A navigation apparatus which can improve convenience of navigation by starting assisting of the movement without delay by inferring a predetermined route. This navigation apparatus includes a system controlling unit for setting a predetermined route which a vehicle travels, for inferring whether or not the vehicle deviates from a predetermined route and continues during travel of the vehicle along a predetermined route, when it is inferred that the vehicle deviates from the predetermined route, which then begins to set an inferred predetermined route where the vehicle should travel after deviating from the predetermined route.
摘要翻译：一种导航装置，其可以通过推断预定路线而不延迟地开始辅助运动来提高导航的便利性。该导航装置包括用于设定车辆行驶的预定路线的系统控制单元，用于推断车辆是否偏离预定路线，并且在车辆沿着预定路线行驶期间继续行驶，当推测出车辆偏离从预定路线开始，该预定路线开始设定推定的预定路线，其中车辆在偏离预定路线之后应行驶。

7. 发明授权

US06448908B1 On-vehicle navigation system having route searching function 失效
标题翻译：具有路线搜索功能的车载导航系统
公开(公告)号：US06448908B1
公开(公告)日：2002-09-10
申请号：US09110397
申请日：1998-07-06
申请人： Makoto Hijikata
发明人： Makoto Hijikata
IPC分类号： G08G1123
CPC分类号： G08G1/096827 , G01C21/3484
摘要： An on-vehicle navigation system having a route searching function for automatically selecting a guiding route to a destination in consideration of run experiences of the user. Run experience data indicative of the run experience is formed every road unit which the vehicle has run and is stored, a plurality of traveling routes which a vehicle can run between a start point and the destination are searched for and weights of the road units in the traveling route and the corresponding run experience data is obtained from memory for each of the plurality of traveling routes in the route searching operation, the weight of each road unit in the traveling route is corrected by the corresponding run experience data for each of the plurality of traveling routes, a sum value of the corrected weights corresponding to the road units in the traveling route is calculated for each of the plurality of traveling routes, and a traveling route of which sum value is the minimum is selected from the plurality of traveling routes. The route including the roads which the user has run previously is preferentially selected as a guiding route, so that a route search which makes the most of the run experience of the user is performed.
摘要翻译：一种具有路线搜索功能的车载导航系统，用于考虑到用户的运行体验自动选择到目的地的引导路线。在车辆运行和存储的每个道路单元上形成表示运行经验的运行经验数据，搜索车辆可以在起点和目的地之间运行的多条行驶路线，并且搜索车辆中的道路单元的重量在路线搜索操作中，对于多个行驶路线中的每一个，从存储器获得行驶路线和相应的行驶经验数据，行驶路线中的每个道路单元的重量由相应的运行经验数据对于多个行驶路线中的每一个，计算行驶路线中与道路单位对应的修正权重的和值，并且从多个行驶路线中选择和值为最小的行驶路线。优先选择包括用户以前运行的道路的路线作为引导路线，从而进行充分利用用户的跑步体验的路线搜索。

8. 发明授权

US06356835B2 Map information display device for navigation apparatus 有权
标题翻译：导航仪地图信息显示装置
公开(公告)号：US06356835B2
公开(公告)日：2002-03-12
申请号：US09262738
申请日：1999-03-05
申请人： Katsuyoshi Hayashi , Kenichiro Yano , Makoto Hijikata
发明人： Katsuyoshi Hayashi , Kenichiro Yano , Makoto Hijikata
IPC分类号： G01C2100
CPC分类号： G01C21/3673
摘要： In a map information display device, the map data extracting unit extracts character data corresponding to characters from map data corresponding to the map, and the map data converting unit converts the map data including no character data to a bird's-eye-view map data. The character data converting unit selects designated character data from the extracted character data and converts the character data other than the designated character data to bird's-eye-view character data. Then, the combining unit combines the bird's-eye-view character data, the bird's-eye-view map data and the designated character data to produce combined bird's-eye-view data. Then, the display unit displays the map of bird's-eye-view using the combined bird's-eye-view data.
摘要翻译：在地图信息显示装置中，地图数据提取部从与地图对应的地图数据中提取与字符对应的字符数据，地图数据变换部将不包含字符数据的地图数据变换为鸟瞰图数据。字符数据转换单元从提取的字符数据中选择指定的字符数据，并将除了指定的字符数据之外的字符数据转换为鸟瞰视角字符数据。然后，组合单元将鸟瞰视角字符数据，鸟瞰图地图数据和指定字符数据组合，以产生组合鸟瞰数据。然后，显示单元使用组合的鸟瞰图数据显示鸟瞰图。

9. 发明授权

US5089899A Recording medium playing apparatus which permits changes in the display position of a reproduced image 失效
标题翻译：允许改变再现图像的显示位置的记录介质播放装置
公开(公告)号：US5089899A
公开(公告)日：1992-02-18
申请号：US449193
申请日：1989-12-13
申请人： Satoru Nomura , Yoshihisa Nagai , Tetsuro Emi , Koji Miyashita , Hiroyuki Higuchi , Makoto Hijikata
发明人： Satoru Nomura , Yoshihisa Nagai , Tetsuro Emi , Koji Miyashita , Hiroyuki Higuchi , Makoto Hijikata
IPC分类号： H04N5/92 , G10K15/04 , G11B20/00 , H04N5/262 , H04N5/775 , H04N5/93 , H04N5/937 , H04N5/956 , H04N9/877
CPC分类号： H04N5/956 , H04N21/4334 , H04N5/262 , H04N5/44504 , H04N5/937 , H04N9/877 , H04N21/4104 , H04N21/488 , H04N5/775
摘要： An apparatus for playing a recording medium on which, in addition to a video format signal and a coded information signal, graphic codes including picture information are recorded as the subcode of the coded information signal. The apparatus is structured to generate, as a reading address data, data which varies sequentially by a predetermined value from a value determined in response to a command, and to write sequentially the graphic codes output from an extracting circuit into a memory and subsequently sequentially read out the graphic codes in the order of address indicated by the reading address data. With this feature, the position of the subcode image can be moved on the picture by the video format signal. According to another feature of the invention, the apparatus is structured such that a reading timing signal which has a time relationship determined by a command with respect to a sync signal contained in the video format signal demodulated by a demodulating circuit, and the graphic codes output from the extracting circuit are written into the memory and subsequently sequentially read out in a predetermined order by using the reading timing signal.
摘要翻译：一种用于播放记录介质的装置，除了视频格式信号和编码信息信号之外，还记录有包括图像信息的图形代码作为编码信息信号的子代码。该装置被构造为产生作为读取地址数据的数据，该数据根据响应于命令确定的值依次改变预定值，并且顺序地将从提取电路输出的图形代码写入到存储器中，并且随后顺序读取按照读取地址数据指示的地址顺序排列图形代码。利用该特征，可以通过视频格式信号在图像上移动子代码图像的位置。根据本发明的另一个特征，该装置被构造成使得具有由相对于由解调电路解调的视频格式信号中包含的同步信号的命令确定的时间关系的读取定时信号和图形代码输出从提取电路被写入存储器，然后通过使用读取定时信号以预定的顺序顺序地读出。

10. 发明授权

US5960919A Automatic transmission with a separator for removing oil from the surface of a rotary member 失效
标题翻译：具有用于从旋转构件的表面去除油的分离器的自动变速器
公开(公告)号：US5960919A
公开(公告)日：1999-10-05
申请号：US880919
申请日：1997-06-23
申请人： Fumitomo Yokoyama , Kazuhisa Ozaki , Akihiro Kuroyanagi , Makoto Hijikata , Katsuyuki Asaoka , Akihito Hongoya , Kagenori Fukumura , Atsushi Tabata , Yasuo Hojo
发明人： Fumitomo Yokoyama , Kazuhisa Ozaki , Akihiro Kuroyanagi , Makoto Hijikata , Katsuyuki Asaoka , Akihito Hongoya , Kagenori Fukumura , Atsushi Tabata , Yasuo Hojo
IPC分类号： B60R17/00 , F16H57/04 , F16D13/74
CPC分类号： F16H57/0423 , F16H57/0484 , Y10T74/19991 , Y10T74/2186
摘要： An automatic transmission including at least one rotary member; a rotary member enclosure enclosing the rotary member; and an oil reservoir arranged below the rotary member enclosure for collecting and reserving the oil. An oil separator is located facing the outer circumference of the rotary member for separating the oil adhering to the rotary member. Because the amount of oil left on the surface of the rotary member is reduced, the amount of oil recovered in the oil reservoir is accordingly increased and the level of the oil surface in the oil reservoir is prevented from falling.
摘要翻译：一种包括至少一个旋转构件的自动变速器; 围绕旋转构件的旋转构件外壳; 以及设置在旋转构件外壳下方用于收集和储存油的储油器。油分离器面对旋转构件的外周面，用于分离附着在旋转构件上的油。因为留在旋转构件表面上的油量减少，所以在储油器中回收的油的量相应地增加，并且防止储油器中的油面的水平下降。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式