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    • 1. 发明授权
    • Sustained-release aromatic and method of detecting micro-organism by using the same
    • 持续释放芳香剂及其使用方法检测微生物
    • US06576247B1
    • 2003-06-10
    • US08849421
    • 1999-03-08
    • Takeshi IkemotoHiroko NakatsugawaBun-ichi OkabeKazuo OginoJun-ichi MatsuiMinoru IwamotoAkira FujitaMasayoshi Inui
    • Takeshi IkemotoHiroko NakatsugawaBun-ichi OkabeKazuo OginoJun-ichi MatsuiMinoru IwamotoAkira FujitaMasayoshi Inui
    • A61K700
    • C12Q1/04A61K8/37A61K8/602A61K2800/57A61Q7/00A61Q13/00A61Q15/00
    • The present invention provides a sustained-release aromatic, characterized in that the aromatic comprises at least one perfume derivative as an active component selected from glycosides of perfumes, phosphoric acid ester derivatives of perfumes, amino acid derivatives of perfumes and carboxylic acid derivatives of perfumes, and contains no enzyme or acid which decomposes the perfume derivative, wherein the perfume derivative is decomposed by bacteria usually present on the skin or yeast to release a perfume component to exhibit aroma. The present invention also provides a method for the detection of micro-organisms using the aforesaid sustained-release aromatic. As the sustained-release aromatic of the present invention releases a perfume component only when it is decomposed by micro-organisms such as bacteria usually present on the skin or yeast, the amount of perfumes to be used can be extremely reduced. The sustained-release aromatic of the present invention is also excellent in keeping aroma. The stability with the passage of time of the sustained-release aromatic of the present invention is much better than that of the prior art because the perfume component is contained in the form of derivative. The sustained-release aromatic of the present invention is useful for applications on the skin, head skin or hair of human beings or animals, on clothes, or in drinks and foods, or as an indicator for detecting micro-organisms.
    • 本发明提供一种持续释放芳香族物质,其特征在于该芳香剂包含至少一种作为活性成分的香料衍生物,其选自香料糖苷,香料的磷酸酯衍生物,香料的氨基酸衍生物和香料的羧酸衍生物, 并且不含有分解香料衍生物的酶或酸,其中香料衍生物由通常存在于皮肤或酵母上的细菌分解以释放香料组分以显示香味。 本发明还提供了使用上述缓释芳香族物检测微生物的方法。 作为本发明的持续释放性芳香族物质,只有当通过微生物如通常存在于皮肤或酵母上的细菌分解时才释放香料成分,所以可以极大地减少使用的香料量。 本发明的持续释放芳香剂在保持香气的同时也是优异的。 由于香料成分以衍生物形式包含,所以本发明的持续释放芳香族物质的稳定性比现有技术更好。 本发明的持续释放的芳香剂可用于人或动物的皮肤,头皮或头发,衣服或饮料和食品中的应用,或用作检测微生物的指示剂。