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    • 5. 发明授权
    • Detecting and/or measuring a substance based on a resonance shift of photons orbiting within a microsphere
    • 基于在微球内循环的光子的共振移动来检测和/或测量物质
    • US07491491B2
    • 2009-02-17
    • US10096333
    • 2002-03-12
    • Steven ArnoldIwao Teraoka
    • Steven ArnoldIwao Teraoka
    • C12Q1/68
    • G02B6/241G01N21/7746G01N33/54313G02B6/2821Y10S977/924
    • Detecting and/or measuring a substance based on a resonance shift of photons orbiting within a microsphere of a sensor. Since the resonance of the microsphere has a large quality factor, the sensor is extremely sensitive. The sensor includes the microsphere coupled with at least one optical fiber. The surface of the microsphere includes receptors complementary to the substance. The at least one optical fiber can be provided with at least one additional microsphere having a surface free of the receptors. Resonance shifts observed in such an additional microsphere(s) can be attributed to factors unrelated to the presence of the substance. The resonance shift observed in the microsphere with the receptors can be compensated based on the resonance shift of the additional microsphere(s) to remove the influence of these other factors.
    • 基于在传感器的微球内旋转的光子的共振移动来检测和/或测量物质。 由于微球的共振具有较大的品质因数,所以传感器非常敏感。 传感器包括与至少一个光纤耦合的微球。 微球的表面包括与物质互补的受体。 所述至少一个光纤可以具有至少一个具有无受体表面的附加微球。 在这样的附加微球中观察到的共振位移可以归因于与物质的存在无关的因素。 在具有受体的微球中观察到的共振偏移可以基于附加微球的共振移动来补偿,以消除这些其它因素的影响。
    • 8. 发明申请
    • DETECTING AND/OR MEASURING A SUBSTANCE BASED ON A RESONANCE SHIFT OF PHOTONS ORBITING WITHIN A MICROSPHERE
    • 检测和/或测量基于与MICROSPHERE相连的光子的共振转换的物质
    • US20090190136A1
    • 2009-07-30
    • US12350000
    • 2009-01-07
    • Steven ArnoldIwao Teraoka
    • Steven ArnoldIwao Teraoka
    • G01N21/59
    • G02B6/241G01N21/7746G01N33/54313G02B6/2821Y10S977/924
    • Detecting and/or measuring a substance based on a resonance shift of photons orbiting within a microsphere of a sensor. Since the resonance of the microsphere has a large quality factor, the sensor is extremely sensitive. The sensor includes the microsphere coupled with at least one optical fiber. The surface of the microsphere includes receptors complementary to the substance. The at least one optical fiber can be provided with at least one additional microsphere having a surface free of the receptors. Resonance shifts observed in such an additional microsphere(s) can be attributed to factors unrelated to the presence of the substance. The resonance shift observed in the microsphere with the receptors can be compensated based on the resonance shift of the additional microsphere(s) to remove the influence of these other factors.
    • 基于在传感器的微球内旋转的光子的共振移动来检测和/或测量物质。 由于微球的共振具有较大的品质因数,所以传感器非常敏感。 传感器包括与至少一个光纤耦合的微球。 微球的表面包括与物质互补的受体。 所述至少一个光纤可以具有至少一个具有无受体表面的附加微球。 在这样的附加微球中观察到的共振位移可以归因于与物质的存在无关的因素。 在具有受体的微球中观察到的共振偏移可以基于附加微球的共振移动来补偿,以消除这些其它因素的影响。