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1. 发明授权

US07854918B2 Composition for medical use having improved water-solubility of peptide and metal-labeling efficiency and preparation for medical use comprising metal-labeled peptide 有权
标题翻译：具有改进的肽的水溶性和金属标记效率的用于医疗用途的组合物和包含金属标记的肽的用于医疗用途的制剂
公开(公告)号：US07854918B2
公开(公告)日：2010-12-21
申请号：US10591252
申请日：2005-03-23
申请人： Takayoshi Kawaguchi , Ikuya Seki , Marino Maemura
发明人： Takayoshi Kawaguchi , Ikuya Seki , Marino Maemura
IPC分类号： A61K51/00 , A61M36/14
CPC分类号： A61K51/08 , A61K9/0019 , A61K9/19 , A61K47/183 , A61K47/22 , A61K51/121 , C07K1/13
摘要： By preliminarily dissolving a basic organic compound in an aqueous solvent in which a peptide usable in metal-labeling is to be dissolved, the solubility of the peptide is improved and thus metal-labeling can be carried out without heating. A composition for medical use containing a peptide usable in metal-labeling and a basic organic compound acceptable as a pharmaceutical additive can be utilized as a preparation useful in image diagnosis, radiotherapy and so on.
摘要翻译：通过将碱性有机化合物预先溶解于可溶解金属标记的肽的水性溶剂中，可以提高肽的溶解性，可以不加热进行金属标记。可以使用含有可用于金属标记的肽的医疗用组合物和作为药物添加剂可接受的碱性有机化合物作为用于图像诊断，放射治疗等的制剂。

2. 发明申请

US20070160532A1 Composition for medical use having improved water-solubility of peptide and metal-labeling efficiency and preparation for medical use comprising metal-labeled peptide 有权
标题翻译：具有改进的肽的水溶性和金属标记效率的用于医疗用途的组合物和包含金属标记的肽的用于医疗用途的制剂
公开(公告)号：US20070160532A1
公开(公告)日：2007-07-12
申请号：US10591252
申请日：2005-03-23
申请人： Takayoshi Kawaguchi , Ikuya Seki , Marino Maemura
发明人： Takayoshi Kawaguchi , Ikuya Seki , Marino Maemura
IPC分类号： A61K51/00 , A61K49/10 , C07K7/08
CPC分类号： A61K51/08 , A61K9/0019 , A61K9/19 , A61K47/183 , A61K47/22 , A61K51/121 , C07K1/13
摘要： By preliminarily dissolving a basic organic compound in an aqueous solvent in which a peptide usable in metal-labeling is to be dissolved, the solubility of the peptide is improved and thus metal-labeling can be carried out without heating. A composition for medical use containing a peptide usable in metal-labeling and a basic organic compound acceptable as a pharmaceutical additive can be utilized as a preparation useful in image diagnosis, radiotherapy and so on.
摘要翻译：通过将碱性有机化合物预先溶解于可溶解金属标记的肽的水性溶剂中，可以提高肽的溶解性，可以不加热进行金属标记。可以使用含有可用于金属标记的肽的医疗用组合物和作为药物添加剂可接受的碱性有机化合物作为用于图像诊断，放射治疗等的制剂。

3. 发明授权

US07220827B2 Compound binding to leukocytes and medicinal composition containing the compound in labeled state as the active ingredient 失效
标题翻译：化合物与白细胞结合，含有标记状态的化合物作为活性成分的药物组合物
公开(公告)号：US07220827B2
公开(公告)日：2007-05-22
申请号：US10528771
申请日：2003-09-26
申请人： Ikuya Seki , Takayoshi Kawaguchi , Yoshifumi Shirakami
发明人： Ikuya Seki , Takayoshi Kawaguchi , Yoshifumi Shirakami
IPC分类号： A61K38/04
CPC分类号： C07K7/06 , A61K38/08 , A61K49/14 , A61K51/088 , C07K7/02 , Y02A50/409
摘要： A compound that comprises Met-Leu-Phe or Nle-Leu-Phe serving as the leukocyte-binding site of a formyl peptide receptor (FPR), a binding part comprising Ser or Thr that increases the binding ratio to monocytes and lymphocytes in all leukocytes, a group that can be labeled with a radioactive metal or a paramagnetic metal, and spacers binding the three moieties together shows binding properties specific to all leukocytes, i.e., neutrophils, monocytes and lymphocytes both in vivo and in vitro. Owing to this characteristic, this compound is highly useful in SPECT image diagnosis, PET image diagnosis, MRI image diagnosis and the like, for imaging sites of inflammation.
摘要翻译：包含作为甲酰肽受体（FPR）的白细胞结合位点的Met-Leu-Phe或Nle-Leu-Phe的化合物，包含Ser或Thr的结合部分，其增加与所有白细胞中的单核细胞和淋巴细胞的结合比，可以用放射性金属或顺磁金属标记的基团，以及将三个部分结合在一起的间隔物在体内和体外都显示出对所有白细胞，即嗜中性粒细胞，单核细胞和淋巴细胞特异性的结合特性。由于该特征，该化合物在SPECT图像诊断，PET图像诊断，MRI图像诊断等中对于炎症成像部位是非常有用的。

4. 发明申请

US20060057064A1 Compound binding to leukocytes and medicinal composition containing the compound in labeled state as the active ingredient 失效
标题翻译：化合物与白细胞结合，含有标记状态的化合物作为活性成分的药物组合物
公开(公告)号：US20060057064A1
公开(公告)日：2006-03-16
申请号：US10528771
申请日：2003-09-26
申请人： Ikuya Seki , Takayoshi Kawaguchi , Yoshifumi Shirakami
发明人： Ikuya Seki , Takayoshi Kawaguchi , Yoshifumi Shirakami
IPC分类号： A61K51/00 , A61K38/12
CPC分类号： C07K7/06 , A61K38/08 , A61K49/14 , A61K51/088 , C07K7/02 , Y02A50/409
摘要： A compound binding to leukocytes, which comprises Met-Leu-Phe or Nle-Leu-Phe serving as the leukocyte-binding site of a formyl peptide receptor (FPR), a binding part comprising Ser or Thr elevating the binding ratios to monocytes and lymphocytes in all leukocytes, a group which can be labeled with a radioactive metal or a paramagnetic metal, and a spacer binding them shows binding properties specific to all leukocytes, i.e., neutrophils, monocytes and lymphocytes both in vivo and in vitro and can be labeled with a radioactive metal or a paramagnetic metal. Owing to these characteristics, this compound is highly useful in SPECT image diagnosis, PET image diagnosis, MRI image diagnosis and so on wherein imaging is performed in a site with vigorous leukocyte infiltration accompanied by an immune reaction in an individual.
摘要翻译：与白细胞结合的化合物，其包含作为甲酰基肽受体（FPR）的白细胞结合位点的Met-Leu-Phe或Nle-Leu-Phe，包含Ser或Thr的结合部分提高与单核细胞和淋巴细胞的结合比在所有的白细胞中，可以用放射性金属或顺磁性金属标记的基团和结合它们的间隔基团显示出对体内和体外所有白细胞，即嗜中性粒细胞，单核细胞和淋巴细胞特异性的结合特性，并且可以用放射性金属或顺磁性金属。由于这些特征，该化合物在SPECT图像诊断，PET图像诊断，MRI图像诊断等中非常有用，其中在具有伴随着个体的免疫反应的剧烈白细胞浸润的部位进行成像。

5. 发明授权

US07804965B2 Microphone system and microphone apparatus 失效
标题翻译：麦克风系统和麦克风设备
公开(公告)号：US07804965B2
公开(公告)日：2010-09-28
申请号：US11242085
申请日：2005-10-04
申请人： Takayoshi Kawaguchi , Hiroyuki Yasui
发明人： Takayoshi Kawaguchi , Hiroyuki Yasui
IPC分类号： H04B3/00 , H04H20/47 , H04R5/00
CPC分类号： H04R3/005 , H04N7/147 , H04N7/15
摘要： A microphone system including a main unit for controlling the entire system and microphones having cascade connections from the main unit assuming the main-unit side upstream and the opposite side downstream. The microphone includes communication control means for controlling data transmitted between the main unit and microphones, sound input means for converting collected sound into a digital signal, echo cancellation means for eliminating an echo component in the sound signal, and sound-information generation means for updating the sound information by adding the sound signal of the self-microphone to the sound information of the downstream microphones and upstream transmitting the up data including the updated sound information. The microphone transmits the down data transmitted from the main unit to the down-most microphone in sequence in accordance with the cascade connection and transmits the up data from the down-most microphone to the main unit in reverse sequence.
摘要翻译：一种麦克风系统，包括用于控制整个系统的主单元和具有来自主单元的级联连接的麦克风，假设主单元侧上游和相对侧下游。麦克风包括用于控制在主单元和麦克风之间传输的数据的通信控制装置，用于将收集的声音转换为数字信号的声音输入装置，用于消除声音信号中的回声分量的回声消除装置，以及用于更新的声音信息产生装置通过将自发麦克风的声音信号添加到下游麦克风的声音信息和向上游发送包括更新的声音信息的上行数据的声音信息。麦克风根据级联连接将从主机发送的下行数据顺序发送到最低级的麦克风，并将倒数据从最低级麦克风反向传送到主机。

6. 发明申请

US20080246833A1 VIDEO CONFERENCING APPARATUS, CONTROL METHOD, AND PROGRAM 审中-公开
标题翻译：视频会议设备，控制方法和程序
公开(公告)号：US20080246833A1
公开(公告)日：2008-10-09
申请号：US12062335
申请日：2008-04-03
申请人： Hiroyuki YASUI , Takayoshi Kawaguchi
发明人： Hiroyuki YASUI , Takayoshi Kawaguchi
IPC分类号： H04N7/14
CPC分类号： H04N7/142 , H04N7/15
摘要： A video conferencing apparatus for video conferencing includes: a light emission control means for allowing a light emitting means for emitting a light that is included in a sound collecting means for collecting a sound to emit a light in a certain light emission pattern; a light emitting position detecting means for detecting a light emitting position that is a position of the light in an image obtained by imaging the light from the light emitting means included in the sound collecting means by a first imaging means for imaging; an arranging direction detecting means for detecting an arranging direction that is a direction in which the sound collecting means is arranged based on the light emitting position; and an imaging control means for controlling an imaging direction that is a direction in which a second imaging means for imaging an image takes an image, based on the arranging direction.
摘要翻译：一种用于视频会议的视频会议装置包括：发光控制装置，用于允许发光装置发射包含在声音采集装置中的光，用于收集声音以一定的发光图案发光; 发光位置检测装置，用于通过用于成像的第一成像装置来检测作为通过对包括在声音采集装置中的发光装置对光进行成像而获得的图像中的光的位置的发光位置; 布置方向检测装置，用于基于所述发光位置检测作为布置所述声音收集装置的方向的布置方向; 以及成像控制装置，用于基于排列方向来控制作为用于对图像拍摄的第二成像装置拍摄图像的方向的成像方向。

7. 发明申请

US20070040903A1 Camera controller and teleconferencing system 失效
标题翻译：相机控制器和电话会议系统
公开(公告)号：US20070040903A1
公开(公告)日：2007-02-22
申请号：US11505197
申请日：2006-08-16
申请人： Takayoshi Kawaguchi
发明人： Takayoshi Kawaguchi
IPC分类号： H04N7/14
CPC分类号： H04N7/15 , H04N7/147
摘要： A teleconferencing system includes: a camera system for imaging a plurality of persons; a voice collector for capturing voices generated by a plurality of persons; and a transmitter for multiplexing an image signal acquired from the camera system and a voice signal acquired from the voice collector and transmitting a multiplexed signal via a communication line. The camera system includes: a camera; a driver for changing the viewing direction of the camera; and a camera controller for controlling the driver. The camera controller includes: a face position detection unit; a registration unit; a timing unit; a drive control unit; and a hold time control unit.
摘要翻译：电话会议系统包括：用于对多个人进行成像的照相机系统; 用于捕获由多个人产生的声音的语音收集器; 以及发送器，用于复用从相机系统获取的图像信号和从语音收集器获取的语音信号，并经由通信线路发送多路复用的信号。相机系统包括：相机; 用于改变相机的观看方向的驱动器; 以及用于控制驾驶员的照相机控制器。相机控制器包括：脸部位置检测单元; 注册单位; 定时单元驱动控制单元; 和保持时间控制单元。

8. 发明申请

US20060106836A1 Data processing system, data processing device, data processing method, and computer program 审中-公开
标题翻译：数据处理系统，数据处理设备，数据处理方法和计算机程序
公开(公告)号：US20060106836A1
公开(公告)日：2006-05-18
申请号：US10517060
申请日：2003-05-27
申请人： Madoka Masugi , Noboru Shimada , Makoto Oka , Takayoshi Kawaguchi , Yoshihito Ishibashi , Hiroshi Abe , Nobutaka Toyoshima
发明人： Madoka Masugi , Noboru Shimada , Makoto Oka , Takayoshi Kawaguchi , Yoshihito Ishibashi , Hiroshi Abe , Nobutaka Toyoshima
IPC分类号： G06F17/00 , G06F7/00
CPC分类号： H04L63/0869 , G06F21/33 , G06F21/445 , G06F21/6218 , H04L63/0435 , H04L63/061 , H04L63/0823 , H04L63/104 , H04L63/126 , H04L63/166 , H04L63/20 , H04L2463/102
摘要： A privilege management system enabling effective privilege management, such as confirmation processing of service receiving privileges and so forth, is realized. A group attribute certificate which has, as stored information, group identification information corresponding to a group which is a set of certain devices or certain users, and also has affixed an electronic signature of an issuer, is issued to a service reception entity, and verification is performed by means of signature verification for of the group attribute certificate presented from the user device regarding whether or not there has been tampering, screening is performed regarding whether or not this is a service-permitted group based on group identification information stored in the group attribute certificate by using a group information database, and determination is made regarding whether or not service can be provided, based on the screening. Centralized privilege confirmation corresponding to various user sets or device sets can be made, so management of individual privilege information can be omitted, thereby enabling effective privilege management.
摘要翻译：实现了能够进行有效特权管理的特权管理系统，例如服务接收特权的确认处理等。作为存储信息的组属性证书被发布到服务接收实体，作为存储信息，与特定设备或某些用户的集合对应的组标识信息，并且还附加了发行者的电子签名，并且验证通过对从用户装置呈现的组属性证书的签名验证来执行是否存在篡改，基于存储在该组中的组标识信息来执行是否是服务允许组的筛选通过使用组信息数据库的属性证书，并且基于筛选确定是否可以提供服务。可以进行与各种用户集或设备集相对应的集中式权限确认，可以省略对各个特权信息的管理，从而实现有效的权限管理。

9. 发明申请

US20120075499A1 IMAGE PROCESSING APPARATUS, IMAGE PROCESSING METHOD, AND IMAGE PROCESSING PROGRAM 有权
标题翻译：图像处理设备，图像处理方法和图像处理程序
公开(公告)号：US20120075499A1
公开(公告)日：2012-03-29
申请号：US13236754
申请日：2011-09-20
申请人： Takayoshi Kawaguchi , Takuya Matsumoto
发明人： Takayoshi Kawaguchi , Takuya Matsumoto
IPC分类号： H04N5/235
CPC分类号： H04N5/2353 , H04N5/23245 , H04N5/2352 , H04N5/243 , H04N5/35536 , H04N5/35581
摘要： An image processing apparatus including: a pixel array section in which unit pixels, each having a photoelectric conversion element, are two-dimensionally arranged in a matrix; and a signal processing section determining a signal level by any one of a water gate mode determining the signal level in accordance with a first amount of electric charge based on an electric charge accumulated in the unit pixels, the electric charge more than or equal to a prescribed accumulated electric charge, in a first exposure period or a second amount of electric charge based on all the electric charges accumulated in the unit pixels in a second exposure period including the first exposure period and a multiple exposure mode determining the signal level in accordance with a plurality of amounts of electric charge based on all the electric charges accumulated in the unit pixels in a plurality of exposure periods.
摘要翻译：一种图像处理设备，包括：像素阵列部分，其中具有光电转换元件的单位像素被二维地排列成矩阵; 以及信号处理部，其基于积蓄在单位像素中的电荷，根据第一电荷量确定信号电平的水闸模式中的任一个来确定信号电平，电荷大于或等于在第一曝光期间或第二次电量的基础上，基于在包括第一曝光期间的第二曝光期间累积的全部电荷和根据第一曝光期间确定信号电平的多重曝光模式基于在多个曝光周期中累积在单位像素中的所有电荷的多个电荷量。

10. 发明授权

US08098843B2 Sound source direction detecting apparatus, sound source direction detecting method, and sound source direction detecting camera 失效
标题翻译：声源方向检测装置，声源方向检测方法和声源方向检测摄像机
公开(公告)号：US08098843B2
公开(公告)日：2012-01-17
申请号：US12284455
申请日：2008-09-22
申请人： Takayoshi Kawaguchi , Yasuhiro Kodama , Yohei Sakuraba
发明人： Takayoshi Kawaguchi , Yasuhiro Kodama , Yohei Sakuraba
IPC分类号： H04R3/00 , H04N7/00
CPC分类号： G01S3/801 , G01S3/8083 , G01S3/86
摘要： Disclosed herein is a sound source direction detecting apparatus including: a plurality of microphones configured to collect sounds from a sound source in order to form an audio frame; a frequency decomposition section configured to decompose the audio frame into frequency components; an error range determination section configured to determine the effects of noises collected together with the sounds as an error range relative to phases; a power level dispersion section configured to disperse power levels of the sounds for each of the frequency components decomposed by the frequency decomposition section, on the basis of the error range determined by the error range determination section; a power level addition section configured to add the power levels dispersed by the power level dispersion section; and a sound source direction detection section configured to detect the direction of the sound source based on the phase at which is located the highest of the power levels added by the power level addition section.
摘要翻译：这里公开了一种声源方向检测装置，包括：多个麦克风，被配置为从声源收集声音以形成音频帧; 频率分解部，被配置为将音频帧分解成频率分量; 误差范围确定部分，被配置为将与所述声音一起收集的噪声的影响确定为相对于相位的误差范围; 功率电平分散部，其基于由所述误差范围确定部确定的误差范围，分配由所述频率分解部分解的每个频率分量的声音的功率电平; 功率电平相加部分，被配置为添加由功率电平分散部分分散的功率电平; 以及声源方向检测部，被配置为基于位于功率电平相加部附加的最高功率电平的相位来检测声源的方向。

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