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    • 1. 发明申请
    • Solubilized Composition
    • 溶解组合物
    • US20120010169A1
    • 2012-01-12
    • US13257691
    • 2010-03-09
    • Takashi TeshigawaraKei WatanabeHidefumi Araki
    • Takashi TeshigawaraKei WatanabeHidefumi Araki
    • A61K8/58A61Q19/00
    • C08L71/02A61K8/04A61K8/39A61K8/86A61K8/891A61Q19/00C08G77/14C08K5/5419C08L83/06C08L83/04
    • This invention provides a solubilized composition in which a carboxy-modified silicone is solubilized in a large amount and stably. The solubilized composition is characterized by consisting of (a) one or more nonionic surfactant(s), having a weighted average of the HLB value of 10 to 15, selected from polyoxyethylene alkyl ether type nonionic surfactant represented by the following formula (I) or (II): wherein R1 represents a branched chain alkyl group having 8 to 18 carbon atoms; a represents an integer satisfying 3≦a≦40; any one or more of R2, R3 and R4 are each a branched chain alkyl group having 8 to 18 carbon atoms and the other(s) is a hydroxy group; and b, c and d each represent an integer satisfying 3≦b+c+d≦40,(b) a carboxy-modified silicone, and(c) water, andwherein the amount of (b) the carboxy-modified silicone is three times or less the weight of (a) the nonionic surfactant(s).
    • 本发明提供一种溶解组合物,其中羧基改性的硅氧烷大量且稳定地溶解。 该溶解组合物的特征在于:(a)一种或多种HLB值加权平均值为10〜15的非离子表面活性剂,其选自由下式(I)表示的聚氧乙烯烷基醚型非离子表面活性剂或 (II)表示:其中R1表示碳原子数为8〜18的支链烷基; a表示满足3&nlE的整数; a≦̸ 40; R 2,R 3和R 4中的任何一个或多个各自为具有8至18个碳原子的支链烷基,而另一个为羟基; b,c和d分别表示满足3≦̸ b + c + d≦̸ 40,(b)羧基改性硅氧烷和(c)水的整数,其中(b)羧基改性硅氧烷的量为 (a)非离子表面活性剂的重量的三倍或更少。
    • 2. 发明申请
    • Solubilized Composition
    • 溶解组合物
    • US20120027712A1
    • 2012-02-02
    • US13257352
    • 2010-03-09
    • Takashi TeshigawaraHidefumi ArakiKei Watanabe
    • Takashi TeshigawaraHidefumi ArakiKei Watanabe
    • A61K8/58A61Q5/00A61Q7/00A61Q19/00
    • C08L71/02A61K8/39A61K8/585A61K8/86A61K8/891A61Q19/00C08K5/5419C08K5/549C08L83/04
    • This invention provides a solubilized composition in which a cyclic or straight silicone oil is solubilized in a large amount and stably. The solubilized composition is characterized by comprising (a) a polyoxyethylene alkyl ether type nonionic surfactant represented by the following formula (I): R1—O—(CH2CH2O)a—H  (I) wherein R1 represents a branched chain alkyl group having 8 to 18 carbon atoms; a represents an integer satisfying 3≦a≦20, (b) one or more silicone(s) selected from a cyclic silicone represented by the following formula (II) and a short chain straight silicone represented by the following formula (III): [(CH3)HSi—O—]m  (II) (CH3)3Si—O—[Si(CH3)2O]nSi(CH3)3  (III) wherein m represents an integer satisfying 3≦m≦7; and n represents an integer satisfying 0≦n≦7, and (c) water.
    • 本发明提供一种溶解组合物,其中环状或直链硅油大量且稳定地溶解。 该溶解组合物的特征在于:(a)由下式(I)表示的聚氧乙烯烷基醚型非离子表面活性剂:R1-O-(CH2CH2O)a-H(Ⅰ),其中R1表示支链烷基, 18个碳原子; a表示满足3&nlE的整数; a≦̸ 20,(b)选自由下式(II)表示的环状硅氧烷中的一种或多种硅酮和由下式(III)表示的短链直链硅氧烷:[ (CH3)HSi-O-] m(II)(CH3)3Si-O- [Si(CH3)2O] nSi(CH3)3(Ⅲ)其中m表示满足3&nlE的整数; m& n表示满足0&nlE的整数; n≦̸ 7,(c)水。