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1. 发明授权

US09314749B2 Mixing device, mixing tube, drug solution injecting system, and drug solution mixing method 有权
标题翻译：混合装置，混合管，药液注射系统和药液混合法
公开(公告)号：US09314749B2
公开(公告)日：2016-04-19
申请号：US13639814
申请日：2011-03-28
申请人： Takanobu Yagi , Young Kwang Park , Mitsuo Umezu
发明人： Takanobu Yagi , Young Kwang Park , Mitsuo Umezu
IPC分类号： A61M37/00 , B01F5/00 , A61J1/20 , A61M5/145 , A61M5/168 , B01F3/08 , A61M5/00 , A61M39/22
CPC分类号： B01F5/0068 , A61J1/20 , A61K49/005 , A61K49/0071 , A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/16827 , A61M5/19 , A61M39/223 , A61M2206/16 , B01F3/0865 , B01F5/0057 , B01F2215/0032
摘要： To provide a mixing device, a mixing tube, a drug solution injecting system, and a drug solution mixing method capable of evenly and efficiently mixing a plurality of kinds of drug solutions. The mixing device according to the present invention includes: a swirling flow generating chamber; a first inflow opening for introducing a first drug solution into the swirling flow generating chamber in a direction parallel to a central axis of the swirling flow; a second inflow opening for introducing a second drug solution into the swirling flow generating chamber so as to generate a swirling flow of the second drug solution having a specific gravity lower than that of the first drug solution; an outflow opening for discharging a mixed drug solution; and a narrowing chamber which is interposed between the swirling flow generating chamber and the outflow opening and has a space continuously narrowed toward the outflow opening.
摘要翻译：提供能够均匀有效地混合多种药物溶液的混合装置，混合管，药液注射系统和药物溶液混合方法。根据本发明的混合装置包括：旋流产生室; 第一流入开口，用于将第一药液沿平行于旋流的中心轴的方向引入旋流产生室; 第二流入口，用于将第二药液引入旋流产生室，以产生比第一药物溶液的比重低的第二药液的旋流; 用于排出混合药液的流出口; 以及狭窄室，其设置在旋流产生室和流出口之间，并且具有朝向流出开口连续变窄的空间。

2. 发明申请

US20130028841A1 MIXING DEVICE, MIXING TUBE, DRUG SOLUTION INJECTING SYSTEM, AND DRUG SOLUTION MIXING METHOD 有权
标题翻译：混合装置，混合管，药物溶液注射系统和药物溶液混合方法
公开(公告)号：US20130028841A1
公开(公告)日：2013-01-31
申请号：US13639814
申请日：2011-03-28
申请人： Takanobu Yagi , Young Kwang Park , Mitsuo Umezu
发明人： Takanobu Yagi , Young Kwang Park , Mitsuo Umezu
IPC分类号： B01F5/04 , A61B6/00 , A61K49/00
CPC分类号： B01F5/0068 , A61J1/20 , A61K49/005 , A61K49/0071 , A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/16827 , A61M5/19 , A61M39/223 , A61M2206/16 , B01F3/0865 , B01F5/0057 , B01F2215/0032
摘要： To provide a mixing device, a mixing tube, a drug solution injecting system, and a drug solution mixing method capable of evenly and efficiently mixing a plurality of kinds of drug solutions. The mixing device according to the present invention includes: a swirling flow generating chamber; a first inflow opening for introducing a first drug solution into the swirling flow generating chamber in a direction parallel to a central axis of the swirling flow; a second inflow opening for introducing a second drug solution into the swirling flow generating chamber so as to generate a swirling flow of the second drug solution having a specific gravity lower than that of the first drug solution; an outflow opening for discharging a mixed drug solution; and a narrowing chamber which is interposed between the swirling flow generating chamber and the outflow opening and has a space continuously narrowed toward the outflow opening.
摘要翻译：提供能够均匀有效地混合多种药物溶液的混合装置，混合管，药液注射系统和药物溶液混合方法。根据本发明的混合装置包括：旋流产生室; 第一流入开口，用于将第一药液沿平行于旋流的中心轴的方向引入旋流产生室; 第二流入口，用于将第二药液引入旋流产生室，以产生比第一药物溶液的比重低的第二药液的旋流; 用于排出混合药液的流出口; 以及狭窄室，其设置在旋流产生室和流出口之间，并且具有朝向流出开口连续变窄的空间。

3. 发明申请

US20130109967A1 LEAK DETECTING SENSOR AND CHEMICAL LIQUID INJECTION SYSTEM 有权
标题翻译：泄漏检测传感器和化学液体注射系统
公开(公告)号：US20130109967A1
公开(公告)日：2013-05-02
申请号：US13453108
申请日：2012-04-23
申请人： Young-Kwang Park , Takanobu Yagi , Seiichi Ono , Tomoyuki Kawabe , Tatsuya Ito
发明人： Young-Kwang Park , Takanobu Yagi , Seiichi Ono , Tomoyuki Kawabe , Tatsuya Ito
IPC分类号： H01L31/16 , A61M5/00
CPC分类号： H01L31/16 , A61B1/043 , A61B5/0059 , A61M5/007 , A61M5/14546 , A61M5/16831 , A61M2205/15 , A61M2205/3306
摘要： To provide a leak detecting sensor capable of favorably detecting a leak of a chemical liquid regardless of orientation in fixing to a patient. The leak detecting sensor has a plurality of light-emitting elements 11 each emitting light to be applied to the patient, and a single light-receiving element receiving the light emitted by the plurality of light-emitting elements and reflected by the patient. The plurality of light-emitting elements are placed to surround the single light-receiving element.
摘要翻译：提供一种泄漏检测传感器，其能够有利地检测化学液体的泄漏，而不管方向固定在患者身上。泄漏检测传感器具有多个发光元件11，每个发光元件11发射要施加到患者的光，以及接收由多个发光元件发射并由患者反射的光的单个光接收元件。多个发光元件被放置成围绕单个光接收元件。

4. 发明授权

US09968409B2 System for diagnosing bloodflow characteristics, method thereof, and computer software program 有权
公开(公告)号：US09968409B2
公开(公告)日：2018-05-15
申请号：US14240725
申请日：2012-08-27
申请人： Takanobu Yagi , Young-Kwang Park
发明人： Takanobu Yagi , Young-Kwang Park
IPC分类号： G06G7/50 , A61B19/00 , A61B5/055 , A61B5/026 , G06T19/00 , A61B6/00 , G06F19/00 , A61B5/00 , A61B34/00 , A61B34/10 , A61B90/00 , A61B8/06 , A61B5/02
CPC分类号： A61B34/10 , A61B5/02014 , A61B5/026 , A61B5/055 , A61B5/7275 , A61B5/7435 , A61B6/504 , A61B6/507 , A61B8/06 , A61B17/083 , A61B17/12118 , A61B34/25 , A61B90/37 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61B2576/02 , A61F2/82 , A61F2/95 , G06F17/5009 , G06F19/00 , G06F19/321 , G06T17/00 , G06T19/00 , G06T2210/24 , G06T2210/41 , G16H30/20 , G16H50/50
摘要： This system is a system for analyzing blood flow of a target vascular site by means of simulation, having a fluid analysis unit, by a computer, for determining state quantities of blood flow at each position of a lumen of the target vascular site by means of computation by imposing computational conditions including boundary conditions relating to the blood flow to three-dimensional shape data of the target vascular site; a three-dimensional shape modification unit for modifying the three dimensional shape data by simulating a surgical treatment method and for outputting the three-dimensional shape data after the modification; and a comparison display unit for displaying computed results of before and after the modification of the three-dimensional shape for comparing the results, by causing the fluid analysis unit to re-compute the state quantities based on the three-dimensional shape data after the modification.

5. 发明授权

US09724164B2 Blood-vessel bloodstream simulation system, method therefor, and computer software program 有权
公开(公告)号：US09724164B2
公开(公告)日：2017-08-08
申请号：US14240707
申请日：2012-08-27
申请人： Takanobu Yagi , Young-Kwang Park
发明人： Takanobu Yagi , Young-Kwang Park
IPC分类号： G06F17/50 , A61B19/00 , A61B5/055 , A61B5/026 , G06T19/00 , G06T17/00 , A61B5/00 , A61B17/08 , A61B17/12 , A61F2/82 , A61F2/95 , A61B34/00 , A61B90/00 , A61B6/00 , A61B8/06 , A61B5/02 , G06F19/00 , A61B34/10
CPC分类号： A61B34/10 , A61B5/02014 , A61B5/026 , A61B5/055 , A61B5/7275 , A61B5/7435 , A61B6/504 , A61B6/507 , A61B8/06 , A61B17/083 , A61B17/12118 , A61B34/25 , A61B90/37 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61B2576/02 , A61F2/82 , A61F2/95 , G06F17/5009 , G06F19/00 , G06F19/321 , G06T17/00 , G06T19/00 , G06T2210/24 , G06T2210/41 , G16H30/20 , G16H50/50
摘要： This system is a system for analyzing blood flow which imposes a boundary condition relating to the blood flow to three dimensional shape data of a target vascular site of a subject and divides a lumen of the target vascular site into meshes for obtaining state quantities of the blood flow at each mesh position by means of computation, having: a labeling unit, by a computer, for reading out the three dimensional shape data on the lumen of the target vascular site, and labeling a plurality of vascular elements included in the target vascular based on a size of the cross-sectional area of each of the vascular elements; wherein, the computation of the state quantities is carried out by varying a level of mesh detail for each vascular element based on the labeling according to the size of the cross-sectional area.

6. 发明申请

US20150032435A1 SYSTEM FOR DIAGNOSING BLOODFLOW CHARACTERISTICS, METHOD THEREOF, AND COMPUTER SOFTWARE PROGRAM 有权
标题翻译：用于诊断血液流变特性的系统，其方法和计算机软件程序
公开(公告)号：US20150032435A1
公开(公告)日：2015-01-29
申请号：US14240725
申请日：2012-08-27
申请人： Takanobu Yagi , Young-Kwang Park
发明人： Takanobu Yagi , Young-Kwang Park
IPC分类号： G06F19/00 , A61B5/026 , A61B5/00 , G06T17/00
CPC分类号： A61B34/10 , A61B5/02014 , A61B5/026 , A61B5/055 , A61B5/7275 , A61B5/7435 , A61B6/504 , A61B6/507 , A61B8/06 , A61B17/083 , A61B17/12118 , A61B34/25 , A61B90/37 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61B2576/02 , A61F2/82 , A61F2/95 , G06F17/5009 , G06F19/00 , G06F19/321 , G06T17/00 , G06T19/00 , G06T2210/24 , G06T2210/41 , G16H30/20 , G16H50/50
摘要： This system is a system for analyzing blood flow of a target vascular site by means of simulation, having a fluid analysis unit, by a computer, for determining state quantities of blood flow at each position of a lumen of the target vascular site by means of computation by imposing computational conditions including boundary conditions relating to the blood flow to three-dimensional shape data of the target vascular site; a three-dimensional shape modification unit for modifying the three dimensional shape data by simulating a surgical treatment method and for outputting the three-dimensional shape data after the modification; and a comparison display unit for displaying computed results of before and after the modification of the three-dimensional shape for comparing the results, by causing the fluid analysis unit to re-compute the state quantities based on the three-dimensional shape data after the modification.
摘要翻译：该系统是用于通过模拟来分析目标血管部位的血流量的系统，具有计算机的流体分析单元，用于通过目标血管部位的内腔的每个位置处的血流量的状态借助于通过将包括与血流相关的边界条件的计算条件施加到目标血管部位的三维形状数据来进行计算; 三维形状修改单元，用于通过模拟外科治疗方法并在修改之后输出三维形状数据来修改三维形状数据; 以及比较显示单元，用于显示用于比较结果的三维形状的修改之前和之后的计算结果，使得流体分析单元基于修改后的三维形状数据重新计算状态量。

7. 发明授权

US09905721B2 Leak detecting sensor and chemical liquid injection system 有权
公开(公告)号：US09905721B2
公开(公告)日：2018-02-27
申请号：US13453108
申请日：2012-04-23
申请人： Young-Kwang Park , Takanobu Yagi , Seiichi Ono , Tomoyuki Kawabe , Tatsuya Ito
发明人： Young-Kwang Park , Takanobu Yagi , Seiichi Ono , Tomoyuki Kawabe , Tatsuya Ito
IPC分类号： H01L31/16 , A61M5/00 , A61B5/00 , A61M5/145 , A61M5/168 , A61B1/04
CPC分类号： H01L31/16 , A61B1/043 , A61B5/0059 , A61M5/007 , A61M5/14546 , A61M5/16831 , A61M2205/15 , A61M2205/3306
摘要： To provide a leak detecting sensor capable of favorably detecting a leak of a chemical liquid regardless of orientation in fixing to a patient. The leak detecting sensor has a plurality of light-emitting elements 11 each emitting light to be applied to the patient, and a single light-receiving element receiving the light emitted by the plurality of light-emitting elements and reflected by the patient. The plurality of light-emitting elements are placed to surround the single light-receiving element.

8. 发明申请

US20140343906A1 BLOOD-VESSEL BLOODSTREAM SIMULATION SYSTEM, METHOD THEREFOR, AND COMPUTER SOFTWARE PROGRAM 有权
标题翻译：血液瓶血液模拟系统，其方法和计算机软件程序
公开(公告)号：US20140343906A1
公开(公告)日：2014-11-20
申请号：US14240707
申请日：2012-08-27
申请人： Takanobu Yagi , Young-Kwang Park
发明人： Takanobu Yagi , Young-Kwang Park
IPC分类号： G06F19/00 , G06T17/00
CPC分类号： A61B34/10 , A61B5/02014 , A61B5/026 , A61B5/055 , A61B5/7275 , A61B5/7435 , A61B6/504 , A61B6/507 , A61B8/06 , A61B17/083 , A61B17/12118 , A61B34/25 , A61B90/37 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61B2576/02 , A61F2/82 , A61F2/95 , G06F17/5009 , G06F19/00 , G06F19/321 , G06T17/00 , G06T19/00 , G06T2210/24 , G06T2210/41 , G16H30/20 , G16H50/50
摘要： This system is a system for analyzing blood flow which imposes a boundary condition relating to the blood flow to three dimensional shape data of a target vascular site of a subject and divides a lumen of the target vascular site into meshes for obtaining state quantities of the blood flow at each mesh position by means of computation, having: a labeling unit, by a computer, for reading out the three dimensional shape data on the lumen of the target vascular site, and labeling a plurality of vascular elements included in the target vascular based on a size of the cross-sectional area of each of the vascular elements; wherein, the computation of the state quantities is carried out by varying a level of mesh detail for each vascular element based on the labeling according to the size of the cross-sectional area.
摘要翻译：该系统是用于分析血液流量的系统，其将与血流相关的边界条件施加到受试者的目标血管部位的三维形状数据，并将目标血管部位的内腔分成网孔，以获得血液的状态量通过计算，在每个网格位置处流动，具有：计算机的标签单元，用于读出目标血管部位的内腔上的三维形状数据，以及标记包括在目标血管基中的多个血管元件在每个血管元件的横截面面积的尺寸上; 其中，状态量的计算是通过根据横截面积的大小的标记来改变每个血管元件的网格细节的水平来进行的。

9. 发明申请

US20140316758A1 SYSTEM FOR DIAGNOSING BLOODFLOW CHARACTERISTICS, METHOD THEREOF, AND COMPUTER SOFTWARE PROGRAM 有权
标题翻译：用于诊断血液流变特性的系统，其方法和计算机软件程序
公开(公告)号：US20140316758A1
公开(公告)日：2014-10-23
申请号：US14240666
申请日：2012-08-27
申请人： Takanobu Yagi , Young-Kwang Park
发明人： Takanobu Yagi , Young-Kwang Park
IPC分类号： G06F17/50
CPC分类号： A61B34/10 , A61B5/02014 , A61B5/026 , A61B5/055 , A61B5/7275 , A61B5/7435 , A61B6/504 , A61B6/507 , A61B8/06 , A61B17/083 , A61B17/12118 , A61B34/25 , A61B90/37 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61B2576/02 , A61F2/82 , A61F2/95 , G06F17/5009 , G06F19/00 , G06F19/321 , G06T17/00 , G06T19/00 , G06T2210/24 , G06T2210/41 , G16H30/20 , G16H50/50
摘要： This system is a computer-based system for analyzing a blood flow at a target vascular site of a subject by means of a computer simulation, having a three-dimensional shape extraction unit, by a computer, for reading a captured image at the target vascular site and generating three-dimensional data representing a shape of a lumen of the target vascular site; a fluid dynamics analysis unit, by a computer, for determining state quantities (pressure and flow velocity) of blood flow at each position of the lumen of the target vascular site by means of computation by imposing boundary conditions relating to blood flow to the three-dimensional shape data; a blood flow characteristic determination unit for determining, from the state quantities of the blood flow determined by the fluid dynamics analysis unit, a wall shear stress vector at each position of the lumen wall surface of the target vascular site, determining relative relationship between a direction of the wall shear stress vector at a specific wall surface position and directions of wall shear stress vectors at wall surface positions surrounding the specific wall surface position, and from the morphology thereof, determining characteristics of the blood flow at the specific wall surface position and outputting the same as a determined result; and a display unit, by a computer, for displaying the determined result of the blood flow characteristic which is graphically superposed onto a three-dimensional shape model.
摘要翻译：该系统是一种基于计算机的系统，用于通过计算机模拟来分析受试者的目标血管部位的血流，该计算机仿真具有三维形状提取单元，由计算机读取目标血管的捕获图像并产生表示目标血管部位的内腔形状的三维数据; 计算机的流体动力学分析单元，用于通过将与血流有关的边界条件通过计算来确定目标血管部位的内腔的每个位置处的血流量的状态量（压力和流速）三维形状数据; 血流特性确定单元，用于根据由流体动力学分析单元确定的血流量的状态量确定在目标血管部位的管腔壁表面的每个位置处的壁剪切应力矢量，确定方向在围绕特定壁表面位置的壁表面位置处的特定壁表面位置处的壁剪切应力向量和壁剪切应力向量的方向，以及从其形态，确定特定壁表面位置处的血流特性并输出与确定结果相同; 以及显示单元，通过计算机显示图形地叠加在三维形状模型上的血流特性的确定结果。

10. 发明授权

US09814531B2 System for diagnosing bloodflow characteristics, method thereof, and computer software program 有权
公开(公告)号：US09814531B2
公开(公告)日：2017-11-14
申请号：US14240666
申请日：2012-08-27
申请人： Takanobu Yagi , Young-Kwang Park
发明人： Takanobu Yagi , Young-Kwang Park
IPC分类号： G06G7/50 , A61B19/00 , A61B5/055 , A61B5/026 , G06T19/00 , G06F17/50 , G06T17/00 , A61B5/00 , A61B17/08 , A61B17/12 , A61F2/82 , A61F2/95 , A61B34/00 , A61B90/00 , A61B6/00 , A61B8/06 , A61B5/02 , G06F19/00 , A61B34/10
CPC分类号： A61B34/10 , A61B5/02014 , A61B5/026 , A61B5/055 , A61B5/7275 , A61B5/7435 , A61B6/504 , A61B6/507 , A61B8/06 , A61B17/083 , A61B17/12118 , A61B34/25 , A61B90/37 , A61B2034/104 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61B2576/02 , A61F2/82 , A61F2/95 , G06F17/5009 , G06F19/00 , G06F19/321 , G06T17/00 , G06T19/00 , G06T2210/24 , G06T2210/41 , G16H30/20 , G16H50/50
摘要： This system is a computer-based system for analyzing a blood flow at a target vascular site of a subject by means of a computer simulation, having a three-dimensional shape extraction unit, by a computer, for reading a captured image at the target vascular site and generating three-dimensional data representing a shape of a lumen of the target vascular site; a fluid dynamics analysis unit, by a computer, for determining state quantities (pressure and flow velocity) of blood flow at each position of the lumen of the target vascular site by means of computation by imposing boundary conditions relating to blood flow to the three-dimensional shape data; a blood flow characteristic determination unit for determining, from the state quantities of the blood flow determined by the fluid dynamics analysis unit, a wall shear stress vector at each position of the lumen wall surface of the target vascular site, determining relative relationship between a direction of the wall shear stress vector at a specific wall surface position and directions of wall shear stress vectors at wall surface positions surrounding the specific wall surface position, and from the morphology thereof, determining characteristics of the blood flow at the specific wall surface position and outputting the same as a determined result; and a display unit, by a computer, for displaying the determined result of the blood flow characteristic which is graphically superposed onto a three-dimensional shape model.

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