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    • 6. 发明授权
    • Lookup table device and signal conversion method
    • 查找表设备和信号转换方法
    • US5909185A
    • 1999-06-01
    • US945145
    • 1997-10-20
    • Hiroyuki MurataTakashi YokotaKatsuhiro Miura
    • Hiroyuki MurataTakashi YokotaKatsuhiro Miura
    • G06F5/00H03M7/30H03M7/00
    • H03M7/30
    • A lookup table device is provided which converts a digital input signal into a digital output signal previously defined with respect to the digital input signal. The lookup table device has a delimiter information storage unit 10 for storing delimiter information representing a delimiter in a section of the digital input signal corresponding to the digital output signal, a section deriving unit 12 for deriving a section to which a digital input signal belongs, based on the delimiter information stored in the delimiter information storage unit, when the digital input signal is inputted into the lookup table device, and a signal output unit 14 for outputting a digital output signal corresponding to the section derived by the section deriving unit.
    • PCT No.PCT / JP97 / 00443 Sec。 371日期:1997年10月20日 102(e)1997年10月20日的PCT 1997年2月19日提交PCT提供了一种查找表装置,其将数字输入信号转换为相对于数字输入信号预先定义的数字输出信号。 查找表装置具有定界符信息存储单元10,用于存储表示与数字输出信号相对应的数字输入信号的一部分中的定界符的定界符信息;导出数字输入信号所属区段的区间导出单元12; 基于存储在定界符信息存储单元中的定界符信息,当数字输入信号被输入查找表装置时,以及信号输出单元14,用于输出与由区间导出单元导出的区间对应的数字输出信号。
    • 7. 发明授权
    • CDNA Clones coding for human protein exhibiting a broad cellular
activity spectrum (human interleukin-4)
    • CDNA编码人类蛋白质的克隆显示出广泛的细胞活性谱(人白细胞介素-4)
    • US5552304A
    • 1996-09-03
    • US843958
    • 1986-03-25
    • Frank LeeTakashi YokotaKen-ichi AraiTimothy MosmannDonna Rennick
    • Frank LeeTakashi YokotaKen-ichi AraiTimothy MosmannDonna Rennick
    • A61K38/00C07K14/54C07K16/24C12N15/24C12N15/66C12N15/70C12N15/869C12P21/02C12N1/19C12N1/21C12N5/16C12N15/19
    • C12N15/70C07K14/5406C07K16/247C12N15/66A61K38/00C07K2319/02Y10S514/825Y10S514/885
    • Plasmid vectors are provided that carry cDNA clones coding for polypeptides exhibiting B-cell, T-cell and mast cell stimulatory activities, all of which are enhanced in the presence of other immune-reactive agents. The polypeptides also augment the activity of various CSF's, such as G-CSF and G/M-CSF, and depress proliferation of macrophages in the presence of M-CSF. The cDNA is derived from mRNA isolated from a mammalian cell source, such as T-cells typically after activation with a mitogen. The plasmid vector also contains DNA segments from the SV40 virus, permitting expression of the cDNA after transfection into a mammalian host cell, such as COS cells. Two expressed polypeptides of the present invention from different mammals are about 140 and 150 amino acids in length, including potential leader sequences. An E. coli culture containing a plasmid (pcD-2A-E3) carrying a mouse cDNA insert of the present invention was deposited with the American Type Culture Collection (A.T.C.C.) on Nov. 18, 1985, and designated accession number 53,330. Two additional E. coli cultures, each carrying plasmids with different human cDNA inserts of the present invention, were deposited with the A.T.C.C. as follows: pcD-2Fl-13 (pcD-46) was deposited on Nov. 26, 1985 and designated accession number 53,337 and pcD-125 was deposited on Mar. 7, 1986 and designated accession number 67,029.
    • 提供携带编码表现出B细胞,T细胞和肥大细胞刺激活性的多肽的cDNA克隆的质粒载体,所有这些都在其它免疫反应剂存在下增强。 多肽还增加各种CSF的活性,例如G-CSF和G / M-CSF,并且在M-CSF存在下抑制巨噬细胞的增殖。 cDNA源自哺乳动物细胞来源的mRNA,例如通常用丝裂原活化后的T细胞。 质粒载体还含有来自SV40病毒的DNA片段,其在转染到哺乳动物宿主细胞如COS细胞后能够表达cDNA。 来自不同哺乳动物的本发明的两种表达的多肽的长度为约140和150个氨基酸,包括潜在的前导序列。 含有携带本发明的小鼠cDNA插入片段的质粒(pcD-2A-E3)的大肠杆菌培养物于1985年11月18日保藏于美国典型培养物保藏中心(A.T.C.C.),指定登记号为53,330。 每个携带本发明不同人cDNA插入片段的质粒的两个另外的大肠杆菌培养物与A.T.C.C. 如下:pcD-2Fl-13(pcD-46)于1985年11月26日保藏,指定登记号为53,337,pcD-125于1986年3月7日保藏,指定登记号为67,029。