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    • 7. 发明授权
    • Insulation resistance measurement device and insulation resistance measurement method
    • 绝缘电阻测量装置和绝缘电阻测量方法
    • US08860430B2
    • 2014-10-14
    • US13379515
    • 2010-05-18
    • Takafumi IshiiMasanobu Yoshidomi
    • Takafumi IshiiMasanobu Yoshidomi
    • G01R31/02G01R27/18G01R27/02G01R31/14
    • G01R27/025G01R27/18G01R31/025G01R31/14
    • An object is to detect an insulation failure of a DC circuit with high sensitivity and in safety by means of a simple detection circuit. An insulation resistance measurement device of this invention is a device for measuring an insulation resistance to ground of a DC source circuit and is provided with connection terminals for connections to a positive electrode and a negative electrode of a series power supply, switch elements connected between the connection terminals and the ground potential and configured to switch connections between the connection terminals and the ground potential, resistive elements connected through the switch elements between the connection terminals respectively, and the ground potential, and a voltage detection unit for detecting voltage drops in the resistive elements.
    • 目的是通过简单的检测电路来检测具有高灵敏度和安全性的直流电路的绝缘故障。 本发明的绝缘电阻测量装置是用于测量直流源电路的接地绝缘电阻的装置,并且设置有用于连接到串联电源的正极和负极的连接端子,连接在串联电源 连接端子和地电位,并且被配置为切换连接端子与接地电位之间的连接,分别通过连接端子之间的开关元件连接的电阻元件和接地电位;以及用于检测电阻中的电压降的电压检测单元 元素。
    • 10. 发明申请
    • PROPHYLACTIC/THERAPEUTIC AGENT FOR CANCER
    • 癌症的预防/治疗药物
    • US20090142345A1
    • 2009-06-04
    • US11908675
    • 2005-03-14
    • Shuji SatouTakafumi Ishii
    • Shuji SatouTakafumi Ishii
    • A61K39/395C07K16/00A61P35/00
    • C07K16/2851C07K16/30C07K2317/73C07K2317/76
    • The present invention provides a safe drug that targets a molecule specifically expressed in cancer cells, and that induces cancer cell growth inhibition. More specifically, the present invention provides a neutralizing antibody against a protein comprising the same or substantially the same amino acid sequence as that shown by SEQ ID NO:1, SEQ ID NO:3, SEQ ID NO:5, SEQ ID NO:7 or SEQ ID NO:9, or a partial peptide thereof or a salt thereof, and a prophylactic/therapeutic agent for cancers (for example, breast cancer, ovarian cancer, colorectal cancer, lung cancer, pancreatic cancer) and the like, apoptosis promoter, cancer cell growth suppressant, DDR1 antagonist and the like, comprising the neutralizing antibody.
    • 本发明提供了靶向在癌细胞中特异性表达的分子并且诱导癌细胞生长抑制的安全药物。 更具体地,本发明提供了针对蛋白质的中和抗体,其包含与SEQ ID NO:1,SEQ ID NO:3,SEQ ID NO:5,SEQ ID NO:7所示相同或基本相同的氨基酸序列 或其部分肽或其盐,以及癌症的预防/治疗剂(例如乳腺癌,卵巢癌,结肠直肠癌,肺癌,胰腺癌)等,凋亡启动子 ,癌细胞生长抑制剂,DDR1拮抗剂等,其包含中和抗体。