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1. 发明授权

US11304609B2 Body-worn sensor for characterizing patients with heart failure 有权
公开(公告)号：US11304609B2
公开(公告)日：2022-04-19
申请号：US15985404
申请日：2018-05-21
申请人： TOSENSE, INC.
发明人： Matthew Banet , Susan Meeks Pede , Marshal Singh Dhillon , Kenneth Robert Hunt
IPC分类号： A61B5/0205 , A61B5/00 , A61B5/0531 , A61B5/25 , A61B5/282 , A61B5/11
摘要： The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.

2. 发明授权

US10426357B2 Body-worn sensor for characterizing patients with heart failure 有权
公开(公告)号：US10426357B2
公开(公告)日：2019-10-01
申请号：US15804880
申请日：2017-11-06
申请人： TOSENSE, INC.
发明人： Matthew Banet , Susan Meeks Pede , Marshal Singh Dhillon , Kenneth Robert Hunt
IPC分类号： A61B5/0205 , A61B5/0408 , A61B5/053 , A61B5/00 , A61B5/11
摘要： The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.

3. 发明授权

US10258286B2 Floormat physiological sensor 有权
公开(公告)号：US10258286B2
公开(公告)日：2019-04-16
申请号：US14988671
申请日：2016-01-05
申请人： TOSENSE, INC.
发明人： Matthew Banet , Marshal Singh Dhillon , Susan Meeks Pede , Lauren Nicole Miller Hayward , Arthur Deptala , Jonas Dean Cochran
IPC分类号： A61B5/00 , A61B5/0205 , A61B5/022 , A61B5/0245 , A61B5/053 , A61B5/1455 , G06F19/00
摘要： A stand-on physiological sensor (e.g. floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ECG waveforms. The sensor is similar in configuration to a common bathroom scale and includes electrodes that take electrical measurements from a patient's feet to generate bioimpedance waveforms, which are analyzed digitally to extract various other parameters, as well as a cuff-type blood pressure system that takes physical blood pressure measurements at one of the patient's feet. Blood pressure can also be calculated/derived from the bioimpedance waveforms. Measured parameters are transmitted wirelessly to facilitate remote monitoring of the patient for heart failure, chronic heart failure, end-stage renal disease, cardiac arrhythmias, and other degenerative diseases.

4. 发明授权

US10004460B2 Floormat physiological sensor 有权
公开(公告)号：US10004460B2
公开(公告)日：2018-06-26
申请号：US14988663
申请日：2016-01-05
申请人： TOSENSE, INC.
发明人： Matthew Banet , Marshal Singh Dhillon , Susan Meeks Pede , Lauren Nicole Miller Hayward , Arthur Deptala , Jonas Dean Cochran
IPC分类号： A61B5/0205 , A61B5/00 , A61B5/022 , A61B5/1455 , A61B5/0245 , A61B5/024
CPC分类号： A61B5/6892 , A61B5/002 , A61B5/0205 , A61B5/022 , A61B5/02233 , A61B5/02444 , A61B5/0245 , A61B5/0537 , A61B5/14552 , A61B5/4872 , A61B5/4875 , A61B5/7275 , A61B5/7282 , A61B5/742
摘要： A stand-on physiological sensor (e.g. floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ECG waveforms. The sensor is similar in configuration to a common bathroom scale and includes electrodes that take electrical measurements from a patient's feet to generate bioimpedance waveforms, which are analyzed digitally to extract various other parameters, as well as a cuff-type blood pressure system that takes physical blood pressure measurements at one of the patient's feet. Blood pressure can also be calculated/derived from the bioimpedance waveforms. Measured parameters are transmitted wirelessly to facilitate remote monitoring of the patient for heart failure, chronic heart failure, end-stage renal disease, cardiac arrhythmias, and other degenerative diseases.

5. 发明申请

US20170188959A1 FLOORMAT PHYSIOLOGICAL SENSOR 审中-公开
公开(公告)号：US20170188959A1
公开(公告)日：2017-07-06
申请号：US14988671
申请日：2016-01-05
申请人： TOSENSE, INC.
发明人： Matthew Banet , Marshal Singh Dhillon , Susan Meeks Pede , Lauren Nicole Miller Hayward , Arthur Deptala , Jonas Dean Cochran
IPC分类号： A61B5/00 , A61B5/024
CPC分类号： A61B5/6892 , A61B5/002 , A61B5/0205 , A61B5/02233 , A61B5/0245 , A61B5/0537 , A61B5/14552 , A61B5/4872 , A61B5/4875 , A61B5/7275 , A61B5/7282 , A61B5/742 , G06F19/00
摘要： A stand-on physiological sensor (e.g. floormat) measures vital signs and various hemodynamic parameters, including blood pressure and ECG waveforms. The sensor is similar in configuration to a common bathroom scale and includes electrodes that take electrical measurements from a patient's feet to generate bioimpedance waveforms, which are analyzed digitally to extract various other parameters, as well as a cuff-type blood pressure system that takes physical blood pressure measurements at one of the patient's feet. Blood pressure can also be calculated/derived from the bioimpedance waveforms. Measured parameters are transmitted wirelessly to facilitate remote monitoring of the patient for heart failure, chronic heart failure, end-stage renal disease, cardiac arrhythmias, and other degenerative diseases.

6. 发明授权

US09339201B2 Database and algorithm for evaluating efficacy of an electrophysiology procedure 有权
标题翻译：用于评估电生理过程功效的数据库和算法
公开(公告)号：US09339201B2
公开(公告)日：2016-05-17
申请号：US14048741
申请日：2013-10-08
申请人： TOSENSE, INC.
发明人： Matthew Banet , Gregory Kent Feld , Marshal Singh Dhillon , Adolfo Meza-Guinea , Susan Meeks Pede , Andrew Terry
IPC分类号： A61B5/04 , A61B5/00 , A61B5/024 , A61B5/044
CPC分类号： A61B5/04012 , A61B5/0006 , A61B5/0031 , A61B5/02405 , A61B5/044 , A61B5/6823 , A61B5/7246 , A61B5/7271 , G06F19/00
摘要： The present invention provides an improved, Internet-based system that seamlessly collects cardiovascular data from a patient before, during, and after a procedure for EP or an ID. During an EP procedure, the system collects information describing the patient's response to PES and the ablation process, ECG waveforms and their various features, HR and other vital signs, HR variability, cardiac arrhythmias, patient demographics, and patient outcomes. Once these data are collected, the system stores them on an Internet-accessible computer system that can deploy a collection of user-selected and custom-developed algorithms. Before and after the procedure, the system also integrates with body-worn and/or programmers that interrogate implanted devices to collect similar data while the patient is either ambulatory, or in a clinic associated with the hospital. A data-collection/storage module, featuring database interface, stores physiological and procedural information measured from the patient.
摘要翻译：本发明提供了一种改进的基于互联网的系统，其在EP或ID的过程之前，期间和之后从患者无缝地收集心血管数据。在EP程序期间，系统收集描述患者对PES和消融过程，ECG波形及其各种特征，HR和其他生命体征，HR变异性，心律失常，患者人口统计学和患者结果的反应的信息。收集这些数据后，系统将它们存储在可上网的计算机系统上，该计算机系统可以部署用户选择的和定制开发的算法的集合。在手术之前和之后，该系统还与身体穿着和/或程序员集成，询问植入的装置以收集类似的数据，同时患者是走动的，或在与医院相关的诊所中。具有数据库接口的数据收集/存储模块存储从患者测量的生理和程序信息。

7. 发明授权

US11357453B2 Neck-worn physiological monitor 有权
公开(公告)号：US11357453B2
公开(公告)日：2022-06-14
申请号：US14975571
申请日：2015-12-18
申请人： toSense, Inc.
发明人： Matthew Banet , Marshal Singh Dhillon , Susan Meeks Pede , Kenneth Robert Hunt
IPC分类号： A61B5/05 , A61B5/00 , A61B5/0537 , A61B5/0245 , A61B5/029 , A61B5/02 , A61B5/0205 , G16H40/63 , G16H50/20 , G16H10/65 , A61B5/1455 , A61B5/024 , A61B5/11 , A61B5/021 , A61B5/08
摘要： The invention provides a neck-worn sensor that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the sensor can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.

8. 发明授权

US11129537B2 Body-worn sensor for characterizing patients with heart failure 有权
公开(公告)号：US11129537B2
公开(公告)日：2021-09-28
申请号：US16588752
申请日：2019-09-30
申请人： TOSENSE, INC.
发明人： Matthew Banet , Susan Meeks Pede , Marshal Singh Dhillon , Kenneth Robert Hunt
IPC分类号： A61B5/0205 , A61B5/0531 , A61B5/00 , A61B5/25 , A61B5/282 , A61B5/11
摘要： The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.

9. 发明授权

US10993663B2 Neck-worn physiological monitor 有权
公开(公告)号：US10993663B2
公开(公告)日：2021-05-04
申请号：US15935576
申请日：2018-03-26
申请人： TOSENSE, INC.
发明人： Matthew Banet , Kenneth Robert Hunt , Marshal Singh Dhillon , Susan Meeks Pede
IPC分类号： A61B5/00 , A61B5/021 , A61B5/0205 , A61B5/0531 , A61B5/25 , A61B5/029
摘要： The invention provides a neck-worn sensor that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the sensor can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.

10. 发明授权

US10588528B2 Handheld physiological sensor 有权
公开(公告)号：US10588528B2
公开(公告)日：2020-03-17
申请号：US16278424
申请日：2019-02-18
申请人： TOSENSE, INC.
发明人： Matthew Banet , Marshal Singh Dhillon , Susan Meeks Pede , Lauren Nicole Miller Hayward , Arthur Deptala , Jonas Dean Cochran
IPC分类号： A61B5/0404 , A61B5/0408 , A61B5/0205 , A61B5/00 , A61B5/053 , A61B5/02 , A61B5/1455 , A61B5/024 , A61B5/08 , A61B5/022 , A61B5/0472 , A61B5/029 , A61B5/0245 , A61B5/0452 , A61B5/0456 , A61B5/021
摘要： A handheld device measures all vital signs and some hemodynamic parameters from the human body and transmits measured information wirelessly to a web-based system, where the information can be analyzed by a clinician to help diagnose a patient. The system utilizes our discovery that bio-impedance signals used to determine vital signs and hemodynamic parameters can be measured over a conduction pathway extending from the patient's wrist to a location on their thoracic cavity, e.g. their chest or navel. The device's form factor can include re-usable electrode materials to reduce costs. Measurements made by the handheld device, which use the belly button as a ‘fiducial’ marker, facilitate consistent, daily measurements, thereby reducing positioning errors that reduce accuracy of standard impedance measurements. In this and other ways, the handheld device provides an effective tool for characterizing patients with chronic diseases, such as heart failure, renal disease, and hypertension.

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