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1. 发明申请

US20080009845A1 CRYOSURGICAL PROBE WITH ADJUSTABLE SLIDING APPARATUS 有权
标题翻译： CRYOSURGICAL探头与可调滑动装置
公开(公告)号：US20080009845A1
公开(公告)日：2008-01-10
申请号：US11857095
申请日：2007-09-18
申请人： THACH DUONG , Jay Eum
发明人： THACH DUONG , Jay Eum
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2017/00274 , A61B2017/0046 , A61B2018/00547 , A61B2018/0262 , A61B2090/3925
摘要： A cryosurgical probe assembly that includes a gas delivery assembly, including a stem and a fluid conduit subassembly bonded to the stem. The fluid conduit subassembly delivers and returns cooling fluid used for cryogenic cooling. The fluid conduit subassembly, comprises a shaft for providing a heat exchange surface for cryogenic ablation; a housing securely connected to said shaft; and, an insulation element slideably engaged with an inner surface of the shaft and slideably engaged with the stem. The cryosurgical probe assembly includes an adjustable sliding apparatus that includes a slider assembly securely attached to said insulation tube for slideably guiding the insulation tube along said shaft; and, a button assembly operatively connected to the slider assembly for allowing a user to actuate the slider assembly to provide a desired adjustment of the insulation tube relative to the shaft. A handle assembly is positioned about the housing.
摘要翻译：一种冷冻手术探针组件，其包括气体输送组件，其包括杆和结合到所述杆的流体导管子组件。流体导管子组件输送并返回用于低温冷却的冷却流体。流体导管子组件包括用于提供用于低温消融的热交换表面的轴; 牢固地连接到所述轴的壳体; 以及绝缘元件，其与所述轴的内表面可滑动地接合并且可滑动地与所述杆接合。冷冻手术探针组件包括一个可调节的滑动装置，其包括牢固地附接到所述绝缘管的滑动器组件，用于沿着所述轴可滑动地引导绝缘管; 以及可操作地连接到滑块组件的按钮组件，用于允许使用者致动滑块组件以提供相对于轴的绝缘管的期望调节。手柄组件围绕壳体定位。

2. 发明申请

US20060015093A1 Open system heat exchange catheters and methods of use 审中-公开
标题翻译：开放系统热交换导管及使用方法
公开(公告)号：US20060015093A1
公开(公告)日：2006-01-19
申请号：US11231263
申请日：2005-09-20
申请人： Jay Eum , Thach Duong
发明人： Jay Eum , Thach Duong
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B2018/00041 , A61B2018/046
摘要： Various embodiments of open system heat exchange catheters and methods of use are disclosed. The various catheters can be used with various ablative surgical devices. One specific exemplary use is in conjunction with cryosurgical probes involving ablation of the prostate, in which the integrity of the urethra is desired to be maintained. Other uses involve various heating ablative devices. In one embodiment an injection tube assembly is used to provide heat exchange fluid through the urethra to the bladder where it is then expelled via a suprapubic suction tube. In other embodiments a coaxial tube assembly is utilized which defines a passageway for either expelling the bladder fluid or for providing access to an endoscope. In other embodiments a double lumen assembly is utilized that defines a passageway for expelling bladder fluid.
摘要翻译：公开了开放系统热交换导管和使用方法的各种实施例。各种导管可以与各种烧蚀手术装置一起使用。一个具体的示例性用途是结合涉及前列腺消融的冷冻手术探针，其中期望保持尿道的完整性。其他用途涉及各种加热烧蚀装置。在一个实施例中，注射管组件用于将热交换流体通过尿道提供给膀胱，然后通过耻骨上吸管将其排出。在其它实施例中，使用同轴管组件，其限定用于排出膀胱流体或用于提供对内窥镜的通路的通道。在其他实施例中，利用限定用于排出膀胱流体的通道的双腔组件。

3. 发明申请

US20050192565A1 Detachable cryosurgical probe with breakaway handle 有权
标题翻译：具有分离手柄的可拆卸冷冻手术探头
公开(公告)号：US20050192565A1
公开(公告)日：2005-09-01
申请号：US11116873
申请日：2005-04-28
申请人： Jay Eum , Thach Duong , Paul LaPine
发明人： Jay Eum , Thach Duong , Paul LaPine
IPC分类号： A61B17/00 , A61B18/02
CPC分类号： A61B18/02 , A61B2017/0046 , A61B2018/0262
摘要： The detachable cryosurgical probe includes a disposable probe assembly and a reusable probe assembly. The disposable probe assembly includes a breakaway collar which, when twisted away, activates a finger lock element which provides release of the disposable probe assembly from the reusable probe assembly. Additional features include a safety valve assembly for impeding cryogenic working fluid flow when the disposable probe assembly is detached from the reusable probe assembly and an electrical confirmation assembly for providing electrical confirmation that the disposable probe assembly is connected. Other embodiments include a sliding mechanism that allows for selectively positioning of the vacuum tube relative to the shaft to create an ice ball of the desired size and configuration.
摘要翻译：可拆卸的冷冻手术探针包括一次性探针组件和可重复使用的探针组件。一次性探针组件包括分离套环，当被扭转时，该开口套环激活手指锁定元件，其提供一次性探针组件从可重复使用的探针组件的释放。另外的特征包括一个安全阀组件，用于当一次性探头组件与可重复使用的探头组件分离时阻止低温工作流体流动;以及电气确认组件，用于提供一次性探头组件连接的电气确认。其它实施例包括允许真空管相对于轴选择性定位以产生所需尺寸和构造的冰球的滑动机构。

4. 发明申请

US20070005050A1 Heat exchange catheter and method of use 有权
标题翻译：换热导管及使用方法
公开(公告)号：US20070005050A1
公开(公告)日：2007-01-04
申请号：US11148454
申请日：2005-06-09
申请人： Thach Duong , Jay Eum , Jenny Liu
发明人： Thach Duong , Jay Eum , Jenny Liu
IPC分类号： A61B18/18
CPC分类号： A61F7/12 , A61F7/123 , A61F2007/126
摘要： An inlet flow of heat exchange fluid flows from an inflow housing inlet section, and through an inflow housing main section. It then flows through an inlet fluid passageway formed between an inner balloon and a discharge tube. The flow continues around a distal end of the inner balloon, thus becoming an outlet flow of the heat exchange fluid which is directed through an outlet fluid passageway formed between the inner balloon and an outer balloon, then through an outflow housing main section and finally discharged through an outflow housing outlet section. The inner balloon is in a position offset from the central axis of the catheter. The offset relationship enhances the fluid dynamic properties of the catheter. It provides an increased turbulence, which, in turn, maximizes the heat exchange efficiency.
摘要翻译：热交换流体的入口流从流入壳体入口部分流过流入壳体主体部分。然后流过形成在内气囊和放电管之间的入口流体通道。流动继续围绕内球囊的远端，从而变成热交换流体的出口流动，该热交换流体被引导通过形成在内球囊和外球囊之间的出口流体通道，然后通过流出壳体主区段并最终排出通过流出的外壳出口部分。内囊处于从导管的中心轴线偏移的位置。偏移关系增强了导管的流体动力学特性。它提供了增加的湍流，从而使热交换效率最大化。

5. 发明申请

US20060282039A1 Heat exchange catheter with multi-lumen tube having a fluid return passageway 有权
公开(公告)号：US20060282039A1
公开(公告)日：2006-12-14
申请号：US11417407
申请日：2006-05-04
申请人： Thach Duong , Jay Eum , Jenny Liu
发明人： Thach Duong , Jay Eum , Jenny Liu
IPC分类号： A61F7/12
CPC分类号： A61F7/12 , A61F2007/126
摘要： The catheter includes a multi-lumen tube having an outflow portion and an accessory portion. The accessory portion is integrally formed within an interior volume of the outflow portion. The accessory portion has a cross-section smaller than the outflow portion. The outflow portion is offset from the accessory portion such that they are integrally joined. The space between these portions defines a fluid return passageway and the space within the accessory portion defines an accessory passageway. A flexible outer sleeve cooperates with the multi-lumen tube to form a fluid inlet passageway. During operation, an inlet flow of warming fluid flows through the fluid inlet passageway formed between the outer sleeve and the multi-lumen tube. The flow continues around a distal end of the outflow portion of the multi-lumen tube, thus becoming an outlet flow of the warming fluid which is directed through the fluid return passageway.

6. 发明申请

US20050021014A1 Closed system warming catheter and method of use 审中-公开
标题翻译：封闭系统升温导管及使用方法
公开(公告)号：US20050021014A1
公开(公告)日：2005-01-27
申请号：US10894789
申请日：2004-07-20
申请人： Jay Eum , Thach Duong
发明人： Jay Eum , Thach Duong
IPC分类号： A61B17/00 , A61B18/00 , A61B18/02 , A61B18/04 , A61B18/08 , A61B18/18 , A61F7/00 , A61F7/12
CPC分类号： A61B18/04 , A61B18/02 , A61B18/082 , A61B18/18 , A61B2017/00274 , A61B2018/00041 , A61B2018/00547 , A61B2018/0212 , A61B2018/0293 , A61B2018/046
摘要： An apparatus and method for warming the urethra of a patient during ablative surgery. In one embodiment, at least one ablative surgical device is inserted into a prostate region of the patient. A warming assembly is inserted through the patient's urethra and into the bladder. The warming assembly is operated to warm an outer surface thereof during operation of the ablative surgical devices. The urethra is warmed by the outer surface of the warming assembly to preserve living tissue thereof. In one embodiment, the portion of the warming assembly inserted through the patient's urethra is an electrical coil heated warming catheter subassembly. In another embodiment the inserted portion is a microwave heated tube warming catheter subassembly. Another embodiment comprises an RF heated warming catheter subassembly. An opening is preferably included to provide access for an endoscope or for fluid drainage.
摘要翻译：一种用于在烧蚀手术期间使患者的尿道变暖的装置和方法。在一个实施例中，至少一个烧蚀手术装置插入到患者的前列腺区域中。加热组件穿过患者的尿道插入膀胱。在烧蚀手术装置的操作期间，加热组件被操作以加热其外表面。尿道由加热组件的外表面加热以保持其生物组织。在一个实施例中，通过患者尿道插入的加热组件的部分是电线圈加热的加温导管子组件。在另一个实施例中，插入部分是微波加热管加温导管子组件。另一个实施例包括RF加热的加热导管子组件。优选地包括开口以提供用于内窥镜或流体排出的通路。

7. 发明授权

US06544176B2 Computer guided cryosurgery 有权
标题翻译：电脑导引冷冻手术
公开(公告)号：US06544176B2
公开(公告)日：2003-04-08
申请号：US09957306
申请日：2001-09-20
申请人： Paul W. Mikus , Jay Eum , Wilson S. Wong
发明人： Paul W. Mikus , Jay Eum , Wilson S. Wong
IPC分类号： A61B812
CPC分类号： A61B18/02 , A61B34/10 , A61B2017/00274 , A61B2018/00547 , A61B2090/378
摘要： The present invention is a system for placing cryoprobes in a treatment area of a human patient. The system includes a computer system for displaying an image of a treatment area, a template of suggested cryoprobe palcements in the treatment area and images of actual cryoprobes placed within treatment area. The computer system is programmed to perform the steps of: acquiring the image of the treatment area, determining desired dimensions of the treatment area based on the image of the treatment area, determining the optimal cryoprobe placements in the treatment area based on the determined desired dimensions to provide the template of suggested cryoprobe placement, acquiring the images of actual cryoprobes placed within the treatment area, and overlaying the template of suggested cyroprobe placements on the acquired images of actual cryoprobes. The resulting overlaying is provided on a display of the computer system, thereby allowing the surgeon to compare the actual cryoprobe palcements with the optimal cryoprobe placements as determined by the computer system.
摘要翻译：本发明是一种用于将低温球放置在人类患者的治疗区域中的系统。该系统包括用于显示处理区域的图像的计算机系统，处理区域中的建议的冷冻探针的模板以及放置在治疗区域内的实际冷冻人物的图像。计算机系统被编程以执行以下步骤：获取治疗区域的图像，基于治疗区域的图像确定治疗区域的期望尺寸，基于所确定的期望尺寸确定治疗区域中的最佳冷冻探针放置提供建议的冷冻探针放置的模板，获取放置在治疗区域内的实际冷冻人物的图像，并将建议的荧光探针放置模板叠加在所获取的实际冻结图像上。所得到的覆盖物被提供在计算机系统的显示器上，从而允许外科医生将实际的冷冻探针和与计算机系统确定的最佳冷冻探针放置进行比较。

8. 发明授权

US06694170B1 Computer guided surgery for prostatic nerve sparing 有权
标题翻译：电脑指导手术前列腺神经保护
公开(公告)号：US06694170B1
公开(公告)日：2004-02-17
申请号：US09981336
申请日：2001-10-16
申请人： Paul W. Mikus , Jay Eum , John C. Rewcastle , Jawahar M. Ali
发明人： Paul W. Mikus , Jay Eum , John C. Rewcastle , Jawahar M. Ali
IPC分类号： A61B505
CPC分类号： A61B18/02 , A61B34/10 , A61B2017/00274 , A61B2018/00547 , A61B2090/378 , Y10S128/92
摘要： The computer system is capable of acquiring and displaying images of the prostate of a patient for assisting a surgeon in placing ablative elements in the prostate of the patient. The computer system is programmed with software capable of: 1) determining the dimensions of the prostate; and, 2) determining the dimensions and location of a treatment zone. The treatment zone is determined to include only one neurovascular bundle of the prostate and exclude the other neurovascular bundle of the prostate. The system utilizes the determined dimensions of the prostate and treatment zone for computing the number and location of ablative elements needed to treat the treatment zone while minimizing any adverse effect on the patient's sexual function.
摘要翻译：计算机系统能够获取和显示患者的前列腺的图像，以帮助外科医生将烧伤元件放置在患者的前列腺中。计算机系统用软件编程，能够：1）确定前列腺的尺寸; 以及2）确定治疗区域的尺寸和位置。治疗区被确定为仅包括前列腺的一个神经血管束，并排除前列腺的另一个神经血管束。该系统利用前列腺和治疗区域的确定的尺寸来计算治疗区域所需的烧蚀元件的数量和位置，同时最小化对患者的性功能的任何不利影响。

9. 发明授权

US06485422B1 Computer guided cryosurgery 有权
标题翻译：电脑导引冷冻手术
公开(公告)号：US06485422B1
公开(公告)日：2002-11-26
申请号：US09699938
申请日：2000-10-30
申请人： Paul W. Mikus , Jay Eum , Wilson S. Wong
发明人： Paul W. Mikus , Jay Eum , Wilson S. Wong
IPC分类号： A61B800
CPC分类号： A61B18/02 , A61B34/10 , A61B2017/00274 , A61B2018/00547 , A61B2090/378
摘要： A system for assisting surgeons in performing cryosurgery of the prostate by calculating optimal positions for cryoprobes and providing display based templates for overlay over an ultrasound image display, and displaying actual cryoprobes ultrasound images together with template images so that the surgeon may compare suggested and actual placement of the cryoprobes, and adjust placement accordingly.
摘要翻译：一种用于协助外科医生通过计算低温人体的最佳位置并提供用于叠加在超声图像显示器上的基于显示器的模板来辅助外科医生进行前列腺冷冻手术的系统，以及显示实际的低温超声波图像和模板图像，使得外科医生可以比较建议和实际放置的冰球，并相应调整位置。

10. 发明授权

US6033413A Stent delivery system 失效
公开(公告)号：US6033413A
公开(公告)日：2000-03-07
申请号：US63118
申请日：1998-04-20
申请人： Paul W. Mikus , Jay Eum
发明人： Paul W. Mikus , Jay Eum
IPC分类号： A61F2/00 , A61F11/00
CPC分类号： A61F2/0009
摘要： A stent delivery system for use in placing a stent within the prostatic urethra and ensuring that the stent does not interfere with the closure of the bladder neck sphincter. The delivery system includes a catheter with an anchor which anchors the catheter within the urethra and ensures placement of the stent at a predetermined distance from the bladder neck sphincter. For use with shape memory stents, the catheter includes a warming fluid system in which the endoscope used in the procedure can act as a fluid supply line and as valve spool to control the flow or warming fluid to the stent.

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