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1. 发明申请

US20070264719A1 PARTIALLY PASSIVATED QUANTUM DOTS, PROCESS FOR MAKING, AND SENSORS THEREFROM 有权
标题翻译：部分被动量子功能，制造过程和传感器
公开(公告)号：US20070264719A1
公开(公告)日：2007-11-15
申请号：US11748200
申请日：2007-05-14
申请人： Swadeshmukul Santra , Subir Sabui , Paul Holloway , Heesun Yang
发明人： Swadeshmukul Santra , Subir Sabui , Paul Holloway , Heesun Yang
IPC分类号： G01N23/00
CPC分类号： G01N33/588 , B82Y15/00 , G01N21/648 , G01N21/6489 , G01N21/7703 , G01N2021/7786 , Y10S977/773 , Y10S977/813 , Y10S977/824 , Y10S977/834 , Y10T428/2991 , Y10T428/2998
摘要： A partially passivating core shell particle includes a luminescent nanocrystal core, and a partially passivating semiconducting core shell on a surface of the nanocrystal. The shell allows selected analytes to alter a luminescent response of the core shell particle. A quantum dot-based sensing system includes at least one partially passivating core shell particle, a light source for irradiating the partially passivating core shell particle, and a light detector for receiving emissions from the particle, wherein emissions from the core shell particle change in response to the presence of at least one analyte.
摘要翻译：部分钝化的核壳粒子包括发光纳米晶核和在纳米晶体的表面上的部分钝化的半导体核壳。壳体允许选择的分析物改变核壳颗粒的发光响应。基于量子点的感测系统包括至少一个部分钝化的核壳粒子，用于照射部分钝化的核壳粒子的光源和用于接收来自粒子的发射的光检测器，其中核壳粒子的发射响应变化至少存在一种分析物。

2. 发明申请

US20070269382A1 Nanoparticles and Their Use for Multifunctional Bioimaging 有权
标题翻译：纳米颗粒及其用于多功能生物成像
公开(公告)号：US20070269382A1
公开(公告)日：2007-11-22
申请号：US10590590
申请日：2005-05-02
申请人： Swadeshmukul Santra , Paul Holloway , Robert Mericle , Heesun Yang , Glenn Walter
发明人： Swadeshmukul Santra , Paul Holloway , Robert Mericle , Heesun Yang , Glenn Walter
IPC分类号： A61K49/18 , A61P43/00 , C12N5/06 , G01N21/76 , G01N33/533
CPC分类号： A61K49/0423 , A61K49/0002 , A61K49/0067 , A61K49/085 , A61K49/14 , A61K49/183 , B82Y5/00 , Y10S977/774
摘要： The present invention relates to fluorescent, radio-opaque and magnetic quantum nanoparticles, useful as multifunctional contrast agents or probes for in vivo bioimaging, and methods of their use. The invention provides for multifaceted bioimaging (e.g., intra-arterial pre-operative brain mapping and broad based in vivo diagnostic imaging), including imaging of various cell types, such as stem cells.
摘要翻译：本发明涉及可用作体内生物成像的多功能造影剂或探针的荧光，不透射线和磁性量子纳米粒子及其使用方法。本发明提供了多方面的生物成像（例如，动脉内术前脑图谱和广泛的体内诊断成像），包括各种细胞类型如干细胞的成像。

3. 发明申请

US20050053538A1 Method of producing nanosized oxide powders 失效
标题翻译：生产纳米氧化物粉末的方法
公开(公告)号：US20050053538A1
公开(公告)日：2005-03-10
申请号：US10656717
申请日：2003-09-04
申请人： Paul Holloway , Mostafa Abboudi
发明人： Paul Holloway , Mostafa Abboudi
IPC分类号： C01B13/18 , C01F17/00 , C01G1/02 , C01G15/00 , C01G49/00 , C01G49/06 , C09K11/62 , C09K11/77 , H01B1/08 , H01B1/12
CPC分类号： B82Y30/00 , C01B13/18 , C01B13/185 , C01F17/0043 , C01G1/02 , C01G15/00 , C01G49/00 , C01P2002/54 , C01P2002/72 , C01P2004/03 , C01P2004/62 , C01P2004/64 , C01P2006/12 , C09K11/623 , C09K11/7769 , H01B1/08 , H01B1/122 , Y10S977/775 , Y10S977/777 , Y10S977/811
摘要： A method of forming metal oxide powders includes the steps of solid state mixing of at least one metal nitrate salt and at least one reducing organic acid. The mixture is heated to form a metal oxide powder. A metal oxide precursor intermediate can be formed and then heated to form the metal oxide powder.
摘要翻译：形成金属氧化物粉末的方法包括至少一种金属硝酸盐和至少一种还原性有机酸固态混合的步骤。将混合物加热以形成金属氧化物粉末。可以形成金属氧化物前体中间体，然后加热以形成金属氧化物粉末。

4. 发明授权

US07548059B2 Pipeline inspection tool with spirally arranged sensor blocks 有权
标题翻译：管道检测工具，螺旋排列的传感器块
公开(公告)号：US07548059B2
公开(公告)日：2009-06-16
申请号：US11238686
申请日：2005-09-29
申请人： Ronald J. Thompson , Thomas Cook , George Kucherenko , Paul Holloway
发明人： Ronald J. Thompson , Thomas Cook , George Kucherenko , Paul Holloway
IPC分类号： G01N27/72 , G01R33/12
CPC分类号： F16L55/40 , G01N27/902
摘要： A pipeline inspection tool has a spirally arranged series of blocks, with each block having a magnet and at least one magnetic flux sensor. An axially extending support may be provided which terminates in mounts and the series of blocks may be mounted between the mounts. The support may be arranged so as to permit bending of said series of blocks but resist torsion of said series of blocks. A supporting tendon may extend from a second of the mounts through a first opening in each block around a tendon supporting pulley of the first of the mounts and back through a second opening in each block to the second mount. A compression spring surrounding each arm of the tendon between the tendon support and the series of blocks. The magnet of each block may be arranged such that a like pole of each magnet is at one side of the series of blocks. The poles of each magnet may be longitudinally elongated and the longitudinally elongated poles may be directed along an axis of said tool. The magnetic flux sensors of each block may be between the poles of the magnet of each block.
摘要翻译：管道检查工具具有螺旋排列的块系列，每个块具有磁体和至少一个磁通量传感器。可以提供轴向延伸的支撑件，其终止于安装件，并且一系列块体可以安装在安装件之间。支撑件可以布置成允许所述一系列块的弯曲，但是抵抗所述一系列块的扭转。支撑腱可以从第二个安装座延伸穿过每个块中的第一开口围绕第一安装件的腱支撑滑轮并且通过每个块中的第二开口延伸到第二安装件。围绕腱支撑件和一系列块之间的腱的每个臂的压缩弹簧。每个块的磁体可以被布置成使得每个磁体的相似极在该一系列块的一侧。每个磁体的磁极可以纵向伸长，并且纵向细长的磁极可以沿着所述工具的轴线定向。每个块的磁通量传感器可以在每个块的磁体的极之间。

5. 发明授权

US08939942B2 Needle protection assembly 有权
标题翻译：针保护组件
公开(公告)号：US08939942B2
公开(公告)日：2015-01-27
申请号：US12988366
申请日：2009-04-14
申请人： Frederic Perot , Laurent Barrelle , Kevin David Neale , Bruno Baney , Paul Holloway
发明人： Frederic Perot , Laurent Barrelle , Kevin David Neale , Bruno Baney , Paul Holloway
IPC分类号： A61M5/32 , A61M5/00
CPC分类号： A61M5/326 , A61M5/3272 , A61M2005/3247 , A61M2005/3267
摘要： The application relates to a needle protection assembly (1) comprising:—a supporting element (18) and a needle shield (8),—one locking element (20) located within said needle protection assembly (1) and not accessible to the user,—urging means (24) for displacing said needle shield (8),—a peg (19) located on said supporting element (18) or on said needle shield (8), and a cam (9) located on said needle shield (8) or on said supporting element (18), and—said locking element (20) is not formed by said peg (19) and cam (9). The respective longitudinal axis of the needle shield (8) and of the locking element (20) are merged when said needle shield (8) is in its before use or in use positions, and they form an angle (a) when said needle shield (8) is in its after use position.
摘要翻译：本申请涉及一种针保护组件（1），其包括：支撑元件（18）和针护罩（8）， - 位于所述针保护组件（1）内的一个锁定元件（20），并且用户不可访问，用于移动所述针护罩（8）的楔形装置（24）， - 位于所述支撑元件（18）或所述针护罩（8）上的钉（19）和位于所述针护罩（8）或所述支撑元件（18）上，并且所述锁定元件（20）不由所述钉（19）和凸轮（9）形成。当所述针护罩（8）处于其使用前或使用位置时，针护罩（8）和锁定元件（20）的相应纵向轴线被合并，并且当所述针护罩（8）处于使用后位置。

6. 发明申请

US20060220640A1 Pipeline inspection tool 有权
标题翻译：管道检测工具
公开(公告)号：US20060220640A1
公开(公告)日：2006-10-05
申请号：US11238686
申请日：2005-09-29
申请人： Ronald Thompson , Thomas Cook , George Kucherenko , Paul Holloway
发明人： Ronald Thompson , Thomas Cook , George Kucherenko , Paul Holloway
IPC分类号： G01N27/82
CPC分类号： F16L55/40 , G01N27/902
摘要： A pipeline inspection tool has a spirally arranged series of blocks, with each block having a magnet and at least one magnetic flux sensor. An axially extending support may be provided which terminates in mounts and the series of blocks may be mounted between the mounts. The support may be arranged so as to permit bending of said series of blocks but resist torsion of said series of blocks. A supporting tendon may extend from a second of the mounts through a first opening in each block around a tendon supporting pulley of the first of the mounts and back through a second opening in each block to the second mount. A compression spring surrounding each arm of the tendon between the tendon support and the series of blocks. The magnet of each block may be arranged such that a like pole of each magnet is at one side of the series of blocks. The poles of each magnet may be longitudinally elongated and the longitudinally elongated poles may be directed along an axis of said tool. The magnetic flux sensors of each block may be between the poles of the magnet of each block.
摘要翻译：管道检查工具具有螺旋排列的块系列，每个块具有磁体和至少一个磁通量传感器。可以提供轴向延伸的支撑件，其终止于安装件，并且一系列块体可以安装在安装件之间。支撑件可以布置成允许所述一系列块的弯曲，但是抵抗所述一系列块的扭转。支撑腱可以从第二个安装座延伸穿过每个块中的第一开口围绕第一安装件的腱支撑滑轮并且通过每个块中的第二开口延伸到第二安装件。围绕腱支撑件和一系列块之间的腱的每个臂的压缩弹簧。每个块的磁体可以被布置成使得每个磁体的相似极在该一系列块的一侧。每个磁体的磁极可以纵向伸长，并且纵向细长的磁极可以沿着所述工具的轴线定向。每个块的磁通量传感器可以在每个块的磁体的极之间。

7. 发明申请

US20070212791A1 Differential reflection spectroscopy system and method for detecting explosives and other target materials 有权
标题翻译：差示反射光谱系统及爆炸物和其他目标材料的检测方法
公开(公告)号：US20070212791A1
公开(公告)日：2007-09-13
申请号：US11401791
申请日：2006-04-11
申请人： Rolf Hummel , Ann Fuller , Claus Schollhorn , Paul Holloway
发明人： Rolf Hummel , Ann Fuller , Claus Schollhorn , Paul Holloway
IPC分类号： G01N21/62
CPC分类号： G01N21/31 , G01N21/33 , G01N21/35 , G01N21/3563 , G01N21/55 , G01N33/227 , G01N2001/022 , G01N2021/1793 , G01N2021/3133 , Y10T436/170769 , Y10T436/173076
摘要： A system and method for identifying explosive or other target materials includes the steps of irradiating a first location and a second location spaced apart from the first location from a sample suspected of including explosives with ultraviolet, visible or infrared light, measuring reflected light emanated from the first sample location (R1) and reflected light emanated from the second sample location (R2), and calculating a normalized difference in reflectivity (ΔR/ R), wherein R=(R1+R2)/2 is an average reflectivity. A differential reflection spectrum (DRS) is then generated for the sample where ΔR=R2−R1 is the difference of the reflectivities of the first and the second sample location. One or more explosives if present are identified in the sample based on comparing the DRS for said sample to at least one reference DRS.
摘要翻译：用于识别爆炸物或其他目标材料的系统和方法包括以下步骤：将与第一位置隔开的第一位置和与怀疑包括具有紫外线，可见光或红外光的爆炸物的样品的第二位置照射，测量从第一采样位置（R 1> 1）和从第二采样位置（R 2> 2发出）的反射光，并计算归一化反射率差（ΔR/ O OYYLE =“ 其中 R =（R 1 + R 2/2）/ 2是平均反射率。然后为样品产生差分反射光谱（DRS），其中ΔR= R 2 -R 1 1是第一和第二样品位置的反射率的差。基于将所述样品的DRS与至少一个参考DRS进行比较，在样品中鉴定存在的一种或多种爆炸物。

8. 发明申请

US20050068632A1 High resolution multi-lens imaging device 失效
标题翻译：高分辨率多镜头成像装置
公开(公告)号：US20050068632A1
公开(公告)日：2005-03-31
申请号：US10670679
申请日：2003-09-25
申请人： Paul Holloway , Mark Davidson , Olga Shenderova , Gary McGuire , David Tanner , Arthur Hebard
发明人： Paul Holloway , Mark Davidson , Olga Shenderova , Gary McGuire , David Tanner , Arthur Hebard
IPC分类号： G02B13/06 , H04N5/225 , G02B27/10
CPC分类号： H04N5/23238 , G02B13/06 , H04N5/2251 , H04N5/2254
摘要： An imaging device (30) can include a plurality of lenses (51, 52, 53, 54) mounted on a multi-dimensional support structure (32), a plurality of optical detectors (40) corresponding to the plurality of lenses for capturing an optical signal from at least two lenses among the plurality of lenses, and a processor (34) for combining the optical signal from at least two lenses to form an image and electronically controlling the field of view and a resolution of the image. The plurality of lenses each can include an array of sub-wavelength apertures or a plurality of photon sieve lenses (36).
摘要翻译：成像装置（30）可以包括安装在多维支撑结构（32）上的多个透镜（51,52,53,54），对应于多个透镜的多个光学检测器（40），用于捕获来自多个透镜中的至少两个透镜的光信号以及用于组合来自至少两个透镜的光信号以形成图像并且电子地控制图像的视场和分辨率的处理器（34）。多个透镜各自可以包括亚波长孔径阵列或多个光子筛透镜（36）。

9. 发明申请

US20110270198A1 NEEDLE PROTECTION ASSEMBLY 有权
标题翻译：针头保护装置
公开(公告)号：US20110270198A1
公开(公告)日：2011-11-03
申请号：US12988366
申请日：2009-04-14
申请人： Frederic Perot , Laurent Barrelle , Kevin David Neale , Bruno Baney , Paul Holloway
发明人： Frederic Perot , Laurent Barrelle , Kevin David Neale , Bruno Baney , Paul Holloway
IPC分类号： A61M5/32
CPC分类号： A61M5/326 , A61M5/3272 , A61M2005/3247 , A61M2005/3267
摘要： The application relates to a needle protection assembly (1) comprising:—a supporting element (18) and a needle shield (8),—one locking element (20) located within said needle protection assembly (1) and not accessible to the user,—urging means (24) for displacing said needle shield (8),—a peg (19) located on said supporting element (18) or on said needle shield (8), and a cam (9) located on said needle shield (8) or on said supporting element (18), and—said locking element (20) is not formed by said peg (19) and cam (9). The respective longitudinal axis of the needle shield (8) and of the locking element (20) are merged when said needle shield (8) is in its before use or in use positions, and they form an angle (a) when said needle shield (8) is in its after use position.
摘要翻译：本申请涉及一种针保护组件（1），其包括：支撑元件（18）和针护罩（8）， - 位于所述针保护组件（1）内的一个锁定元件（20），并且用户不可访问，用于移动所述针护罩（8）的楔形装置（24）， - 位于所述支撑元件（18）上或所述针护罩（8）上的钉（19）和位于所述针护罩（8）或所述支撑元件（18）上，并且所述锁定元件（20）不由所述钉（19）和凸轮（9）形成。当所述针护罩（8）处于其使用前或使用位置时，针护罩（8）和锁定元件（20）的相应纵向轴线被合并，并且当所述针护罩（8）处于使用后位置。

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