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1. 发明申请

US20070208436A1 INTEGRATED, MULTI-STEP COMPUTER IMPLEMENTED SYSTEM AND METHOD FOR MEASURING AND IMPROVING MANUFACTURING PROCESSES AND MAXIMIZING PRODUCT RESEARCH AND DEVELOPMENT SPEED AND EFFICIENCY USING HIGH-THROUGHPUT SCREENING AND GOVERNING SEMI-EMPIRICAL MODEL 审中-公开
标题翻译：集成的多步骤计算机实现系统和方法，用于测量和改进制造过程，并通过高速切换筛选和管理半实物模型最大化产品研究和开发速度和效率
公开(公告)号：US20070208436A1
公开(公告)日：2007-09-06
申请号：US11565509
申请日：2006-11-30
申请人： Suvajit Das , Thierry Cresson , Jerzy Skowronski , Randy Hempel , Steve Yang , Brian Rutledge , Ebi Elaahi , Bryan Miller
发明人： Suvajit Das , Thierry Cresson , Jerzy Skowronski , Randy Hempel , Steve Yang , Brian Rutledge , Ebi Elaahi , Bryan Miller
IPC分类号： G05B13/02
CPC分类号： G05B15/02 , G05B13/0265 , G05B13/048 , Y02P90/26
摘要： An integrated multi-step computer-implemented system and method for measuring and improving manufacturing processes and maximizing product research and development speed and efficiency includes a predictive model that predicts output from data input, an optimizer that optimizes input variables based upon desired output variables, and a library that stores data and information. The system further includes an artificial intelligence that receives requests and information from manufacturers and customers, and directs the requests and information to the predictive model if an output prediction is requested, to the optimizer if an optimized input is requested, or to the library if the requests cannot be answered by the predictive model or optimizer. The predictive model, the optimizer, and the library all interconnect with the artificial intelligence. The system further includes a high-throughput screening system that analyzes various material combinations and sends data to the library.
摘要翻译：用于测量和改进制造过程并最大化产品研发速度和效率的集成的多步计算机实现的系统和方法包括预测数据输入的输出的预测模型，基于期望的输出变量优化输入变量的优化器，以及一个存储数据和信息的库。该系统还包括从制造商和客户接收请求和信息的人造智能，并且如果请求了输出预测，则将请求和信息引导到预测模型，如果请求了优化的输入，则将该信息引导到预测模型，或者如果请求无法由预测模型或优化器回答。预测模型，优化器和库都与人工智能互连。该系统还包括高通量筛选系统，其分析各种材料组合并将数据发送到库。

2. 发明申请

US20050228511A1 Computer-implemented system and method for measuring and improving manufacturing processes and maximizing product research and development speed and efficiency 审中-公开
标题翻译：计算机实现的系统和方法，用于测量和改进制造工艺，最大限度地提高产品研发速度和效率
公开(公告)号：US20050228511A1
公开(公告)日：2005-10-13
申请号：US10501561
申请日：2003-01-15
申请人： Suvajit Das , Thierry Cresson , Jerzy Skowronski , Randy Hempel , Steve Yang , Brian Rutledge , Ebi Elaahi , Bryan Miller
发明人： Suvajit Das , Thierry Cresson , Jerzy Skowronski , Randy Hempel , Steve Yang , Brian Rutledge , Ebi Elaahi , Bryan Miller
IPC分类号： G05B13/02 , G05B13/04 , G05B15/02 , G05B19/418 , G06F19/00
CPC分类号： G05B15/02 , G05B13/0265 , G05B13/048 , Y02P90/26
摘要： An integrated multi-step computer-implemented system and method for measuring and improving manufacturing processes and maximizing product research and development speed and efficiency is disclosed. The system includes a predictive model that predicts output from data input, an optimizer that optimizes input variables based upon desired output variables, and a library that stores data and information. The system further includes an artificial intelligence that receives requests and information from manufacturers and customers, and directs the requests and information to the predictive model if an output prediction is requested, to the optimizer if an optimized input is requested, or to the library if the requests cannot be answered by the predictive model or optimizer. The predictive model, the optimizer, and the library all interconnect with the artificial intelligence. The system further includes a high-throughput screening system that analyzes various material combinations and sends data to the library.
摘要翻译：公开了一种用于测量和改进制造过程并最大化产品研发速度和效率的综合多步计算机实现系统和方法。该系统包括预测来自数据输入的输出的预测模型，基于期望的输出变量优化输入变量的优化器，以及存储数据和信息的库。该系统还包括从制造商和客户接收请求和信息的人造智能，并且如果请求了输出预测，则将请求和信息引导到预测模型，如果请求了优化的输入，则将该信息引导到预测模型，或者如果请求无法由预测模型或优化器回答。预测模型，优化器和库都与人工智能互连。该系统还包括高通量筛选系统，其分析各种材料组合并将数据发送到库。

3. 发明申请

US20050139778A1 User customizable plate handling for MALDI mass spectrometry 审中-公开
标题翻译：用于MALDI质谱的用户可定制的板处理
公开(公告)号：US20050139778A1
公开(公告)日：2005-06-30
申请号：US11063412
申请日：2005-02-22
申请人： Gregor Overney , Bryan Miller
发明人： Gregor Overney , Bryan Miller
IPC分类号： H01J27/00 , H01J49/04 , H01J49/16
CPC分类号： H01J49/0418 , H01J49/0027
摘要： Methods for specifying the layout of a MALDI sample plate are provided. In general, the methods involve creating a file containing sample plate layout parameters that describe the layout of a MALDI sample plate, and storing the file on a computer readable medium prior to placement of the MALDI sample plate into a MALDI ion source. In many embodiments, the file includes information about the size or shape of the sample plate, or information about the size, shape or position of a sample on the sample plate. In many embodiments, a MALDI sample plate is placed in a MALDI ion source and a stored layout file for the sample plate is accessed and used to position an area of the sample plate in a laser beam. The subject methods, kits and apparatus find use in a variety of different mass spectrometry applications.
摘要翻译：提供了用于指定MALDI样品板的布局的方法。通常，该方法涉及创建一个包含样品板布局参数的文件，该参数描述了MALDI样品板的布局，并在将MALDI样品板放入MALDI离子源之前将该文件存储在计算机可读介质上。在许多实施例中，文件包括关于样品板的尺寸或形状的信息，或关于样品板上样品的尺寸，形状或位置的信息。在许多实施例中，将MALDI样品板放置在MALDI离子源中，并存储用于样品板的存储的布局文件，并将其用于将样品板的区域定位在激光束中。主题方法，试剂盒和仪器可用于各种不同的质谱应用。

4. 发明申请

US20050139779A1 User customizable plate handling for MALDI mass spectrometry 有权
公开(公告)号：US20050139779A1
公开(公告)日：2005-06-30
申请号：US11063486
申请日：2005-02-22
申请人： Gregor Overney , Bryan Miller
发明人： Gregor Overney , Bryan Miller
IPC分类号： H01J27/00 , H01J49/04 , H01J49/16
CPC分类号： H01J49/0418 , H01J49/0027
摘要： Methods for specifying the layout of a MALDI sample plate are provided. In general, the methods involve creating a file containing sample plate layout parameters that describe the layout of a MALDI sample plate, and storing the file on a computer readable medium prior to placement of the MALDI sample plate into a MALDI ion source. In many embodiments, the file includes information about the size or shape of the sample plate, or information about the size, shape or position of a sample on the sample plate. In many embodiments, a MALDI sample plate is placed in a MALDI ion source and a stored layout file for the sample plate is accessed and used to position an area of the sample plate in a laser beam. The subject methods, kits and apparatus find use in a variety of different mass spectrometry applications.

5. 发明申请

US20170049240A1 COMPACT, PORTABLE ELEVATING DEVICE FOR A LOWER LIMB 审中-公开
标题翻译：紧凑型便携式电梯装置
公开(公告)号：US20170049240A1
公开(公告)日：2017-02-23
申请号：US15345316
申请日：2016-11-07
申请人： Bryan Miller
发明人： Bryan Miller
IPC分类号： A47C16/02 , A61F5/01
CPC分类号： A47C16/025 , A61F5/0195
摘要： A device and method for maintaining a user's legs in an elevated position is presented. In particular, the embodiments comprise a base plate having a front surface and a rear surface, a calf cup and heel cup integrated with the front surface, a plurality of retractable leg members, a plurality of hinges, an attachment means comprising preferably a plurality of hook and loop fasteners, and a plurality of gripping caps. The base plate is adaptable to attach with the user's leg or footwear. The plurality of retractable leg members is adaptable to operate in a deployed configuration and/or in a stored configuration, and a locking mechanism is presented. In user, the device allows the user's leg to rest such that the foot is tilted inward or outward from the body. Finally, in the stored configuration, the plurality of retractable leg members becomes parallel with the rear surface of the base plate, thereby allowing the user to perform body movements without removing the leg support device.
摘要翻译：提出了一种用于将用户的腿保持在升高位置的装置和方法。特别地，实施例包括具有前表面和后表面的基板，与前表面一体形成的小腿杯和跟部杯，多个可缩回的腿部构件，多个铰链，附接装置优选地包括多个钩环紧固件和多个夹紧盖。底板适用于与使用者的腿或鞋类连接。多个可伸缩的腿部构件适于在展开的构造和/或存储的构造中操作，并且呈现锁定机构。在用户身上，该装置允许使用者的腿静止，使得脚从身体向内或向外倾斜。最后，在所存储的构造中，多个可伸缩腿部件与基板的后表面平行，从而允许使用者在不移动腿支撑装置的情况下执行身体动作。

6. 发明申请

US20090305397A1 Cellular entity maturation and transportation systems 审中-公开
标题翻译：细胞实体成熟和运输系统
公开(公告)号：US20090305397A1
公开(公告)日：2009-12-10
申请号：US11908845
申请日：2006-03-16
申请人： John Robert Dodgson , Robin Fortt , Malcolm Austen , Bryan Miller , Ray Cattini
发明人： John Robert Dodgson , Robin Fortt , Malcolm Austen , Bryan Miller , Ray Cattini
IPC分类号： C12M1/14
CPC分类号： B01L3/5085 , B01L2200/147 , B01L2300/10 , B01L2300/1827 , B01L2300/1855 , C12M23/12 , C12M23/24 , C12M23/38
摘要： A device for transporting at least one cellular entity during culture or maturation, the device comprising a substrate having one or more wells, said one or more wells being adapted to hold a cellular entity in a fluid, lid means for preventing entry or exit of the cellular entity from the one or more wells and fluid transport means connecting the one or more wells to enable flow of fluid or diffusion of chemical species. The apparatus alternatively or in addition comprise a module for transporting a payload at a controlled temperature, the module comprising an outer housing, an outer thermally insulating region, an inner thermally insulating region, and a heat sinking region located between the inner and outer thermally insulating regions, the inner thermally insulating region defining a cavity for receiving a payload, and heating means.
摘要翻译：一种用于在培养或成熟期间运送至少一个细胞实体的装置，所述装置包括具有一个或多个孔的基底，所述一个或多个孔适于将细胞实体保持在流体中，用于防止进入或离开来自所述一个或多个井的细胞实体和连接所述一个或多个井的流体输送装置，以使流体或化学物质的扩散流动。该装置可选地或另外包括用于在受控温度下运输有效载荷的模块，该模块包括外部壳体，外部热绝缘区域，内部热绝缘区域和位于内部和外部隔热层之间的散热区域区域，内部热绝缘区域限定用于接收有效载荷的空腔，以及加热装置。

7. 发明授权

US09492016B2 Compact, portable elevating device for a lower limb 有权
标题翻译：紧凑型便携式升降装置，用于下肢
公开(公告)号：US09492016B2
公开(公告)日：2016-11-15
申请号：US13315164
申请日：2011-12-08
申请人： Bryan Miller
发明人： Bryan Miller
IPC分类号： A47C16/00 , A47C16/02
CPC分类号： A47C16/025 , A61F5/0195
摘要： A device and method for maintaining a user's legs in an elevated position is presented. In particular, the embodiments comprise a base plate having a front surface and a rear surface, a calf cup and heel cup integrated with the front surface, a plurality of retractable leg members, a plurality of hinges, an attachment means comprising preferably a plurality of hook and loop fasteners, and a plurality of gripping caps. The base plate is adaptable to attach with the user's leg or footwear. The plurality of retractable leg members is adaptable to operate in a deployed configuration allowing the user's leg to rest thereon and/or in a stored configuration wherein the leg members become parallel with the rear surface of the base plate, and a locking mechanism is presented.
摘要翻译：提出了一种用于将用户的腿保持在升高位置的装置和方法。特别地，实施例包括具有前表面和后表面的基板，与前表面一体形成的小腿杯和跟部杯，多个可缩回的腿部构件，多个铰链，附接装置优选地包括多个钩环紧固件和多个夹紧盖。底板适用于与使用者的腿或鞋类连接。多个可伸缩腿部件适于在展开构型中操作，允许使用者的腿搁置在其上和/或以其中腿部件与基板的后表面平行的存储结构，并且呈现锁定机构。

8. 发明授权

US07181412B1 Systems and methods for collecting consumer data 有权
标题翻译：用于收集消费者数据的系统和方法
公开(公告)号：US07181412B1
公开(公告)日：2007-02-20
申请号：US09532890
申请日：2000-03-22
申请人： Gian Fulgoni , Magid Abraham , Michael Brown , Adam Davis , Bryan Miller
发明人： Gian Fulgoni , Magid Abraham , Michael Brown , Adam Davis , Bryan Miller
IPC分类号： G06F17/30
CPC分类号： G06Q30/02 , G06Q10/06375 , G06Q30/0203 , G06Q30/0204 , G06Q30/0205 , G06Q30/0236 , G06Q30/0239 , G06Q30/0277 , H04L67/22 , H04L69/329 , Y10S707/99931
摘要： All of an internet user's internet data is routed to a known domain on the internet, from which it is routed on to the intended recipient. The domain includes proxy servers which proxy the user's WWW data requests to the domain, and database servers which filter and build a database of the user's internet usage. Particular data concerning certain behaviors of interest, such as purchasing data, is filtered into the database, and can form the basis for numerous market measures.
摘要翻译：所有互联网用户的互联网数据都被路由到互联网上的已知域，从而将其路由到预期的接收者。域包括代理用户对域的WWW数据请求的代理服务器，以及过滤和构建用户互联网使用数据库的数据库服务器。有关某些特定行为的具体数据（如采购数据）被过滤到数据库中，可以形成许多市场措施的基础。

9. 发明授权

US10405669B2 Compact, portable elevating device for a lower limb 有权
公开(公告)号：US10405669B2
公开(公告)日：2019-09-10
申请号：US15345316
申请日：2016-11-07
申请人： Bryan Miller
发明人： Bryan Miller
IPC分类号： A47C16/00 , A47C16/02 , A61F5/01
摘要： A device and method for maintaining a user's legs in an elevated position. In particular, a base plate, a plurality of retractable leg members, a plurality of hinges, an attachment means. The base plate is adaptable to attach with the user's leg or footwear. The plurality of retractable leg members is adaptable to operate in a deployed configuration and/or in a stored configuration, and a locking mechanism is presented. In use, the device allows the user's leg to rest such that the foot is tilted inward or outward from the body. Finally, in the stored configuration, the plurality of retractable leg members becomes parallel with the rear surface of the base plate, thereby allowing the user to perform body movements without removing the leg support device.

10. 发明申请

US20120312306A1 Compact, Portable Elevating Device for a Lower Limb 审中-公开
标题翻译：用于下肢的紧凑便携式升降装置
公开(公告)号：US20120312306A1
公开(公告)日：2012-12-13
申请号：US13315164
申请日：2011-12-08
申请人： Bryan Miller
发明人： Bryan Miller
IPC分类号： A61G15/00
CPC分类号： A47C16/025 , A61F5/0195
摘要： A device and method for maintaining a user's legs in an elevated position is presented. In particular, the embodiments comprise a base plate having a front surface and a rear surface, a calf cup and heel cup integrated with the front surface, a plurality of retractable leg members, a plurality of hinges, an attachment means comprising preferably a plurality of hook and loop fasteners, and a plurality of gripping caps. The base plate is adaptable to attach with the user's leg or footwear. The plurality of retractable leg members is adaptable to operate in a deployed configuration allowing the user's leg to rest thereon and/or in a stored configuration wherein the leg members become parallel with the rear surface of the base plate, and a locking mechanism is presented.
摘要翻译：提出了一种用于将用户的腿保持在升高位置的装置和方法。特别地，实施例包括具有前表面和后表面的基板，与前表面一体形成的小腿杯和跟部杯，多个可缩回的腿部构件，多个铰链，附接装置优选地包括多个钩环紧固件和多个夹紧盖。底板适用于与使用者的腿或鞋类连接。多个可伸缩腿部件适于在展开构型中操作，允许使用者的腿搁置在其上和/或以其中腿部件与基板的后表面平行的存储结构，并且呈现锁定机构。

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