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1. 发明申请

US20130052690A1 PCR PRIMER AND METHOD FOR REDUCING NON-SPECIFIC NUCLEIC ACID AMPLIFICATION USING A PHOTOLABILE PROTECTING GROUP 审中-公开
标题翻译：用于减轻非特异性核酸放大的PCR引物和方法使用可溶性保护基团
公开(公告)号：US20130052690A1
公开(公告)日：2013-02-28
申请号：US13584524
申请日：2012-08-13
申请人： Sung-min CHI , Sung-ouk JUNG , Sun-ok JUNG , Joon-ho KIM
发明人： Sung-min CHI , Sung-ouk JUNG , Sun-ok JUNG , Joon-ho KIM
IPC分类号： C07H21/04 , C07H19/10 , C12M1/42 , C07H19/20 , C12N9/12 , C12P19/34
CPC分类号： C12Q1/6848 , C07H19/06 , C07H19/16 , C07H21/04 , C12P19/34 , Y02P20/55 , C12Q2523/319 , C12Q2525/186 , C12Q2549/101
摘要： A primer or primer pair comprising a 3′-photolabile group, and a method of amplifying nucleic acids with controlled polymerization using the primer or primer pair, as well as related compositions, kits, and device for amplifying nucleic acids.
摘要翻译：包含3'-光不稳定基团的引物或引物对，以及使用引物或引物对扩增具有受控聚合的核酸的方法，以及用于扩增核酸的相关组合物，试剂盒和装置。

2. 发明申请

US20100329931A1 SENSING SWITCH AND DETECTING METHOD USING THE SAME 有权
标题翻译：感应开关及其检测方法
公开(公告)号：US20100329931A1
公开(公告)日：2010-12-30
申请号：US12833095
申请日：2010-07-09
申请人： Kyu-tae YOO , Joon-ho KIM , Jun-hong MIN , Sung-ouk JUNG , Ji-na NAMGOONG , Kui-hyun KIM , Jeo-young SHIM , Kak NAMKOONG
发明人： Kyu-tae YOO , Joon-ho KIM , Jun-hong MIN , Sung-ouk JUNG , Ji-na NAMGOONG , Kui-hyun KIM , Jeo-young SHIM , Kak NAMKOONG
IPC分类号： G01N27/00
CPC分类号： G01N33/54373
摘要： Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance; a receptor binding region on an upper surface of an end portion of the sensing plate; an electric or magnetic field generation device that induces deflection of the sensing plate when a receptor bound to the receptor binding region is selectively bound to an electrically or magnetically active ligand; and a pair of switching electrodes that are separated by a predetermined distance and is connected when the sensing plate contacts the substrate due to the deflection of the sensing plate. A target material need not be labelled, a signal processing of a fluorescent or electrical detection signal using an analysis apparatus is not required, and a signal can be directly decoded by confirming whether a current flows through the switch.
摘要翻译：提供了一种感测开关和使用该感测开关的感测方法。感测开关包括：基板; 底物上的支撑物; 感测板，其与所述支撑体的一侧连接并且与所述基板平行预定距离; 在感测板的端部的上表面上的受体结合区域; 当与受体结合区结合的受体选择性地结合到电或磁性活性配体时，引起感测板偏转的电场或磁场产生装置; 以及一对分离预定距离的开关电极，并且当感测板由于感测板的偏转而与基板接触时被连接。目标材料不需要标注，不需要使用分析装置的荧光或电检测信号的信号处理，并且可以通过确认电流是否流过开关直接解码信号。

3. 发明申请

US20090170211A1 SENSING SWITCH AND DETECTING METHOD USING THE SAME 有权
标题翻译：感应开关及其检测方法
公开(公告)号：US20090170211A1
公开(公告)日：2009-07-02
申请号：US12272183
申请日：2008-11-17
申请人： Kyu-tae YOO , Joon-ho KIM , Jun-hong MIN , Sung-ouk JUNG , Ji-na NAMGOONG , Kui-hyun KIM , Jeo-young SHIM , Kak NAMKOONG
发明人： Kyu-tae YOO , Joon-ho KIM , Jun-hong MIN , Sung-ouk JUNG , Ji-na NAMGOONG , Kui-hyun KIM , Jeo-young SHIM , Kak NAMKOONG
IPC分类号： G01N27/00
CPC分类号： G01N33/54373
摘要： Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance; a receptor binding region on an upper surface of an end portion of the sensing plate; an electric or magnetic field generation device that induces deflection of the sensing plate when a receptor bound to the receptor binding region is selectively bound to an electrically or magnetically active ligand; and a pair of switching electrodes that are separated by a predetermined distance and is connected when the sensing plate contacts the substrate due to the deflection of the sensing plate. A target material need not be labelled, a signal processing of a fluorescent or electrical detection signal using an analysis apparatus is not required, and a signal can be directly decoded by confirming whether a current flows through the switch.
摘要翻译：提供了一种感测开关和使用该感测开关的感测方法。感测开关包括：基板; 底物上的支撑物; 感测板，其与所述支撑体的一侧连接并且与所述基板平行预定距离; 在感测板的端部的上表面上的受体结合区域; 当与受体结合区结合的受体选择性地结合到电或磁性活性配体时，引起感测板偏转的电场或磁场产生装置; 以及一对分离预定距离的开关电极，并且当感测板由于感测板的偏转而与基板接触时被连接。目标材料不需要标注，不需要使用分析装置的荧光或电检测信号的信号处理，并且可以通过确认电流是否流过开关直接解码信号。

4. 发明申请

US20080073214A1 ELECTRODIALYSIS APPARATUS AND ELECTRODIALYSIS METHOD USING THE SAME 有权
标题翻译：电化学装置和使用该方法的电解方法
公开(公告)号：US20080073214A1
公开(公告)日：2008-03-27
申请号：US11737448
申请日：2007-04-19
申请人： Hun-joo LEE , Soo-suk LEE , Joon-ho KIM , Sung-ouk JUNG , In-ho LEE
发明人： Hun-joo LEE , Soo-suk LEE , Joon-ho KIM , Sung-ouk JUNG , In-ho LEE
IPC分类号： B01J47/00 , C02F1/42 , C02F1/469
CPC分类号： B01D61/422 , B01D2311/243 , B01D2313/02 , B01D2313/10 , B01D2313/26 , B01D2313/30 , B01D2313/50 , B01D2321/185
摘要： An electrodialysis apparatus includes a sample chamber including first and second dialysis membranes and filled with a sample between the first dialysis membrane and the second dialysis membrane, an anode chamber including an anode and filled with a first chamber solution between the anode and the first dialysis membrane, and a cathode chamber including a cathode and filled with a second chamber solution between the cathode and the second dialysis membrane. In particular, when a voltage is applied to the anode and the cathode, ionic materials of the sample move to the anode and cathode chambers.
摘要翻译：电渗析装置包括：样品室，包括第一和第二透析膜，并在第一透析膜和第二透析膜之间填充样品;阳极室，包括阳极，并在阳极和第一透析膜之间填充第一室溶液以及包括阴极并在阴极和第二透析膜之间填充有第二室溶液的阴极室。特别地，当向阳极和阴极施加电压时，样品的离子材料移动到阳极室和阴极室。

5. 发明申请

US20130137165A1 GENE ANALYSIS DEVICE 有权
标题翻译：基因分析装置
公开(公告)号：US20130137165A1
公开(公告)日：2013-05-30
申请号：US13608533
申请日：2012-09-10
申请人： Won-jong JUNG , Sun-ok JUNG , Won-seok CHUNG , Chin-sung PARK , Joon-ho KIM , Kak NAMKOONG
发明人： Won-jong JUNG , Sun-ok JUNG , Won-seok CHUNG , Chin-sung PARK , Joon-ho KIM , Kak NAMKOONG
IPC分类号： C12M1/42
CPC分类号： B01L3/502715 , B01L2300/0654 , B01L2300/0816 , G01N21/6452 , G01N2021/0314 , G01N2021/0325 , G01N2021/058 , G01N2021/6463
摘要： A gene analysis device including an illumination optical system radiating exciting light onto a sample solution; a microfluidic device for forming a bio-reaction space of the sample solution and including at least one micro-chamber in which a reflection pattern is formed; and a detection optical system for detecting a fluorescence signal generated by a bio-reaction in the micro-chamber and comprising a photodetector.
摘要翻译：一种基因分析装置，包括将激发光照射到样品溶液上的照明光学系统; 微流体装置，用于形成样品溶液的生物反应空间，并且包括至少一个其中形成有反射图案的微室; 以及检测光学系统，用于检测由微室中的生物反应产生的荧光信号，并包括光电检测器。

6. 发明申请

US20120309004A1 MICRO-DEVICE AND METHODS FOR DISRUPTING CELLS 有权
标题翻译：用于破坏细胞的微器件和方法
公开(公告)号：US20120309004A1
公开(公告)日：2012-12-06
申请号：US13492179
申请日：2012-06-08
申请人： Kyu-youn HWANG , Joon-ho KIM , Sung-hong KWON , Chin-sung PARK , Hee-kyun LIM , Sun-ok JUNG , Won-jong JUNG
发明人： Kyu-youn HWANG , Joon-ho KIM , Sung-hong KWON , Chin-sung PARK , Hee-kyun LIM , Sun-ok JUNG , Won-jong JUNG
IPC分类号： C12M1/40 , C12Q1/68 , G01N1/28
CPC分类号： C12M47/06 , B01L3/502753 , B01L2300/0816 , B01L2300/0867 , B01L2400/0481 , C12N1/06
摘要： A micro-device for disrupting cells includes a first chamber in which the cells are disrupted, a second chamber which is pressurized and depressurized, a flexible membrane which separates the first chamber and the second chamber and is vibrated by pressuring and depressurizing the second chamber, and a micro-unit confined in the first chamber, where the micro-unit disrupts the cells in the first chamber.
摘要翻译：用于破坏电池的微型装置包括其中电池被破坏的第一室，被加压和减压的第二室，分离第一室和第二室的柔性膜，并且通过对第二室进行加压和减压而振动，以及限制在第一室中的微单元，其中微单元破坏第一室中的单元。

7. 发明申请

US20120141999A1 GENE ANALYSIS APPARATUS AND GENE ANALYSIS METHOD USING THE SAME 有权
标题翻译：基因分析装置和使用该基因的基因分析方法
公开(公告)号：US20120141999A1
公开(公告)日：2012-06-07
申请号：US13176777
申请日：2011-07-06
申请人： Chin-sung PARK , Won-jong JUNG , Joon-ho KIM , Kak NAMKOONG , Kyu-youn HWANG , Won-seok CHUNG , Hee-kyun LIM , Sung-hong KWON , Sun-ok JUNG
发明人： Chin-sung PARK , Won-jong JUNG , Joon-ho KIM , Kak NAMKOONG , Kyu-youn HWANG , Won-seok CHUNG , Hee-kyun LIM , Sung-hong KWON , Sun-ok JUNG
IPC分类号： C12Q1/68 , C12M1/34
CPC分类号： B01L7/52 , B01L3/502715 , B01L2200/027 , B01L2200/028 , B01L2200/04 , B01L2200/0605 , B01L2200/0621 , B01L2200/0684 , B01L2200/10 , B01L2200/16 , B01L2300/0627 , B01L2300/0816 , B01L2300/087 , B01L2300/0874 , B01L2300/0887 , B01L2300/18 , B01L2400/0487 , B01L2400/06 , B01L2400/0655 , C12Q1/68 , G01N21/75
摘要： A gene analysis apparatus includes a sample preparation chip in which a polymerase chain reaction (“PCR”) sample is prepared, a PCR chip in which a PCR is performed on the PCR sample, and a package layer on which the sample preparation chip and the PCR chip are mounted. The package layer includes a channel through which a material flows from the sample preparation chip to the PCR chip. The sample preparation chip and the PCR chip are on a same side or on opposing sides of the package layer.
摘要翻译：基因分析装置包括准备了聚合酶链式反应（“PCR”）样品的样品制备芯片，对PCR样品进行PCR的PCR芯片，以及将样品制备芯片和 PCR芯片安装。封装层包括材料从样品制备芯片流向PCR芯片的通道。样品制备芯片和PCR芯片在封装层的相同侧或相对侧上。

8. 发明申请

US20120107912A1 CELL LYSIS DEVICE AND METHODS OF LYSING CELLS OR VIRUSES 有权
标题翻译：细胞检测装置和遗传细胞或病毒的方法
公开(公告)号：US20120107912A1
公开(公告)日：2012-05-03
申请号：US13284364
申请日：2011-10-28
申请人： Kyu-youn HWANG , Joon-ho KIM , Sung-hong KWON , Chin-sung PARK , Hee-kyun LIM , Sun-ok JUNG , Won-jong JUNG
发明人： Kyu-youn HWANG , Joon-ho KIM , Sung-hong KWON , Chin-sung PARK , Hee-kyun LIM , Sun-ok JUNG , Won-jong JUNG
IPC分类号： C12M1/00 , C12N1/20 , C12N5/04 , C12N1/14 , C12N7/00 , C12N5/07
CPC分类号： C12M1/00 , C12M1/33 , C12M47/06
摘要： A method of lysing at least one of a cell and a virus, the method including: contacting a sample, which includes at least one of a cell and a virus, with a plurality of beads which are disposed in a first chamber to obtain a combination of the sample and the beads; and agitating the combination of the sample and the beads to lyse the at least one of the cell and the virus, wherein in the first chamber a liquid volume fraction is 0.6 or less, and wherein the liquid volume fraction is a value obtained by dividing a liquid volume of the first chamber by a pure void volume equivalent to a sum of the liquid volume of the first chamber and a void volume of the first chamber.
摘要翻译：一种裂解细胞和病毒中的至少一种的方法，所述方法包括：将包括细胞和病毒中的至少一种的样品与设置在第一室中的多个珠接触以获得组合的样品和珠粒; 并搅拌样品和珠的组合以裂解细胞和病毒中的至少一种，其中在第一室中液体体积分数为0.6或更小，并且其中液体体积分数是通过将第一室的液体体积相当于第一室的液体体积和第一室的空隙体积的总和的纯空隙体积。

9. 发明申请

US20120107823A1 MICRO-DEVICE AND METHODS FOR DISRUPTING CELLS 有权
标题翻译：用于破坏细胞的微装置和方法
公开(公告)号：US20120107823A1
公开(公告)日：2012-05-03
申请号：US13275871
申请日：2011-10-18
申请人： Kyu-youn HWANG , Joon-ho KIM , Sung-hong KWON , Chin-sung PARK , Hee-kyun LIM , Sun-ok JUNG , Won-jong JUNG
发明人： Kyu-youn HWANG , Joon-ho KIM , Sung-hong KWON , Chin-sung PARK , Hee-kyun LIM , Sun-ok JUNG , Won-jong JUNG
IPC分类号： C12Q1/68 , C12M1/00
CPC分类号： C12Q1/6806 , C12M1/33 , C12M47/06
摘要： A micro-device for disrupting cells includes a first chamber in which the cells are disrupted, a second chamber which is pressurized and depressurized, a flexible membrane which separates the first chamber and the second chamber and is vibrated by pressuring and depressurizing the second chamber, and a micro-unit confined in the first chamber, where the micro-unit disrupts the cells in the first chamber
摘要翻译：用于破坏电池的微型装置包括其中电池被破坏的第一室，被加压和减压的第二室，分离第一室和第二室的柔性膜，并且通过对第二室进行加压和减压而振动，以及限制在第一室中的微单元，其中微单元破坏第一室中的单元

10. 发明申请

US20120064576A1 METHOD AND COMPOSITION FOR ENHANCING EFFICIENCY AND SENSITIVITY IN POLYMERASE CHAIN REACTION 有权
标题翻译：聚合酶链反应中提高效率和灵敏度的方法和组合
公开(公告)号：US20120064576A1
公开(公告)日：2012-03-15
申请号：US13069969
申请日：2011-03-23
申请人： Sun-ok JUNG , Hee-kyun LIM , Kyu-youn HWANG , Joon-ho KIM , Sung-hong KWON
发明人： Sun-ok JUNG , Hee-kyun LIM , Kyu-youn HWANG , Joon-ho KIM , Sung-hong KWON
IPC分类号： C12P19/34 , C12N9/12
CPC分类号： C12Q1/6806 , C12Q1/686 , C12Q2527/125
摘要： Methods and compositions for enhancing reaction efficiency and sensitivity in polymerase chain reaction (PCR) are disclosed.
摘要翻译：公开了用于提高聚合酶链反应（PCR）中的反应效率和灵敏度的方法和组合物。

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