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1. 发明授权

US09393201B2 Oxaliplatin nanoparticles and method for preparing same 有权
标题翻译：奥沙利铂纳米颗粒及其制备方法
公开(公告)号：US09393201B2
公开(公告)日：2016-07-19
申请号：US13497208
申请日：2010-09-20
申请人： Sung Jae Lee , Young Hoon Kim , Sang Heon Lee , Kab Sig Kim
发明人： Sung Jae Lee , Young Hoon Kim , Sang Heon Lee , Kab Sig Kim
IPC分类号： A61K9/50 , A61K9/14 , A61K31/555 , A61K9/00 , A61K9/10 , A61K47/38 , A61K9/20 , A61K9/48
CPC分类号： A61K9/146 , A61K9/0095 , A61K9/10 , A61K9/2027 , A61K9/4866 , A61K31/555 , A61K47/38 , Y10T428/2982
摘要： The present invention relates to a nanoparticle of oxaliplatin, which is a water-soluble active substance, a pharmaceutical composition containing the same, and a method for preparing an orally administrable oxaliplatin nanoparticle by 5 emulsifying a lipid mixture solution wherein a solid lipid and a surfactant are mixed in an aqueous mixture solution wherein oxaliplatin and a specific cosolvent are mixed and then removing the solid lipid and the cosolvent using a supercritical fluid gas.
摘要翻译：本发明涉及奥沙利铂的纳米粒子，其为水溶性活性物质，含有该纳米粒子的药物组合物，以及通过乳化脂质混合溶液制备可口服奥沙利铂纳米粒子的方法，其中固体脂质和表面活性剂在其中混合奥沙利铂和特定助溶剂的混合水溶液中混合，然后使用超临界流体气体除去固体脂质和助溶剂。

2. 发明申请

US20120177728A1 OXALIPLATIN NANOPARTICLES AND METHOD FOR PREPARING SAME 有权
标题翻译： OXALIPLATIN纳米颗粒及其制备方法
公开(公告)号：US20120177728A1
公开(公告)日：2012-07-12
申请号：US13497208
申请日：2010-09-20
申请人： Sung Jae Lee , Young Hoon Kim , Sang Heon Lee , Kab Sig Kim
发明人： Sung Jae Lee , Young Hoon Kim , Sang Heon Lee , Kab Sig Kim
IPC分类号： A61K31/282 , A61K9/48 , B32B5/16 , A61K9/00 , A61P35/00 , B82Y40/00 , B82Y5/00
CPC分类号： A61K9/146 , A61K9/0095 , A61K9/10 , A61K9/2027 , A61K9/4866 , A61K31/555 , A61K47/38 , Y10T428/2982
摘要： The present invention relates to a nanoparticle of oxaliplatin, which is a water-soluble active substance, a pharmaceutical composition containing the same, and a method for preparing an orally administrable oxaliplatin nanoparticle by emulsifying a lipid mixture solution wherein a solid lipid and a surfactant are mixed in an aqueous mixture solution wherein oxaliplatin and a specific cosolvent are mixed and then removing the solid lipid and the cosolvent using a supercritical fluid gas.By providing oxaliplatin, which is currently available only in injection form for parenteral administration, in the form of a nanoparticle, the present invention allows for the development of orally administrable oxaliplatin which is stable against gastric acid and has improved bioavailability, thereby improving patient compliance through avoiding the inconvenience of injection and greatly reducing medical cost. Since the oxaliplatin nanoparticle can be prepared economically using a relatively inexpensive supercritical fluid producing facility, it can be prepared via a simple process with high yield in commercial scale.
摘要翻译：本发明涉及奥沙利铂的纳米粒子，其为水溶性活性物质，含有该纳米粒子的药物组合物，以及通过乳化脂质混合溶液制备口服奥沙利铂纳米粒子的方法，其中固体脂质和表面活性剂为在其中混合奥沙利铂和特定共溶剂的混合物水溶液中混合，然后使用超临界流体气体除去固体脂质和助溶剂。通过提供目前仅以注射用于肠胃外给药的奥沙利铂作为纳米颗粒的形式，本发明允许开发对胃酸稳定的可口服奥沙利铂，并且具有改善的生物利用度，从而通过避免注射带来的不便，大大降低医疗成本。由于奥沙利铂纳米颗粒可以使用相对便宜的超临界流体生产设备经济地制备，所以可以通过工业规模的高产率的简单方法制备。

3. 发明授权

US09464539B2 Waste heat recovery device for a marine vessel 有权
标题翻译：船用废热回收装置
公开(公告)号：US09464539B2
公开(公告)日：2016-10-11
申请号：US14364655
申请日：2011-12-06
申请人： Moon Ho Son , Gun Il Park , Sung Jae Lee , Ho Ki Lee , Jung Kun Jin , Jae Woong Choi
发明人： Moon Ho Son , Gun Il Park , Sung Jae Lee , Ho Ki Lee , Jung Kun Jin , Jae Woong Choi
IPC分类号： F01K15/04 , F01K23/06 , F01K25/08 , F01K27/02 , F01K23/10
CPC分类号： F01K15/04 , F01K23/065 , F01K23/10 , F01K25/08 , F01K27/02
摘要： A waste heat recovery device for a marine vessel is disclosed. According to the embodiments of the present invention, the waste heat recovery device for a marine vessel includes: a heat exchanger, which recovers heat from the exhaust fumes discharged from the engine, to heat a first refrigerant under uniform pressure; a turbine which is driven by adiabatically expanding the first refrigerant heated under uniform pressure; a condenser which condenses the adiabatically expanded first refrigerant; and a heat exchanging pump which compresses the condensed first refrigerant so as to re-circulate the compressed first refrigerant to the heat exchanger.
摘要翻译：公开了一种用于船舶的废热回收装置。根据本发明的实施例，用于船舶的废热回收装置包括：热交换器，其从发动机排出的废气中回收热量，以在均匀的压力下加热第一制冷剂; 涡轮机，其通过绝热膨胀在均匀压力下加热的第一制冷剂驱动; 冷凝器，其将绝热膨胀的第一制冷剂冷凝; 以及热交换泵，其压缩冷凝的第一制冷剂，以将压缩的第一制冷剂再循环到热交换器。

4. 发明申请

US20100125209A1 Probe For Ultrasound System And Method Of Manufacturing The Same 有权
标题翻译：超声波探头及其制造方法
公开(公告)号：US20100125209A1
公开(公告)日：2010-05-20
申请号：US12621328
申请日：2009-11-18
申请人： Sung Jae Lee , Jung Lim Park , Jae Yk Kim
发明人： Sung Jae Lee , Jung Lim Park , Jae Yk Kim
IPC分类号： A61B8/14 , H04R31/00
CPC分类号： B06B1/0629 , A61B8/08 , A61B8/44 , A61B8/4483 , H01L2924/0002 , Y10T29/49005 , H01L2924/00
摘要： A probe for an ultrasound system, and a method of manufacturing the same are disclosed. The probe includes a backing layer, an electrode part formed on the backing layer, and a piezoelectric member installed to the electrode part. The probe is manufactured by connecting the piezoelectric member to the PCB via a unidirectional conduction part, instead of soldering which requires difficult and laborious operations, thereby allowing easy connection therebetween while reducing an operation time for connection.
摘要翻译：公开了一种用于超声系统的探针及其制造方法。探针包括背衬层，形成在背衬层上的电极部分和安装在电极部分上的压电部件。通过单向导通部件将压电部件连接到PCB来制造探针，代替焊接，这需要困难和费力的操作，从而允许在其间容易连接，同时减少连接的操作时间。

5. 发明授权

US09414809B2 Probe for ultrasonic diagnostic apparatus and method of manufacturing the same 有权
标题翻译：超声波诊断仪的探头及其制造方法
公开(公告)号：US09414809B2
公开(公告)日：2016-08-16
申请号：US12912656
申请日：2010-10-26
申请人： Sung Jae Lee , Jung Lim Park , Jae Yk Kim
发明人： Sung Jae Lee , Jung Lim Park , Jae Yk Kim
IPC分类号： A61B8/00 , B06B1/06 , G10K11/00
CPC分类号： A61B8/4281 , B06B1/0622 , G10K11/004 , Y10T29/49005
摘要： A probe for an ultrasonic diagnostic apparatus and a method of manufacturing the same are disclosed. The probe includes a sound matching layer having a mounting groove, a piezoelectric member mounted on the mounting groove, a first connector interconnected to the sound matching layer, and a second connector interconnected to the piezoelectric member. The probe permits interconnection of the piezoelectric member to the first and second connectors to be performed rapidly and easily through a single bonding operation, thereby reducing manufacturing time while facilitating the manufacture of the probe.
摘要翻译：公开了一种用于超声波诊断装置的探针及其制造方法。探头包括具有安装槽的声音匹配层，安装在安装槽上的压电元件，与声音匹配层相互连接的第一连接器和与压电元件互连的第二连接器。该探针允许压电元件与第一和第二连接器的互连通过单一粘合操作快速且容易地进行，从而在促进探针的制造的同时缩短制造时间。

6. 发明申请

US20140345280A1 WASTE HEAT RECOVERY DEVICE FOR A MARINE VESSEL 有权
标题翻译：用于海运船舶的废热回收装置
公开(公告)号：US20140345280A1
公开(公告)日：2014-11-27
申请号：US14364655
申请日：2011-12-06
申请人： Moon Ho Son , Gun Il Park , Sung Jae Lee , Ho Ki Lee , Jung Kun Jin , Jae Woong Choi
发明人： Moon Ho Son , Gun Il Park , Sung Jae Lee , Ho Ki Lee , Jung Kun Jin , Jae Woong Choi
IPC分类号： F01K15/04 , F01K27/02
CPC分类号： F01K15/04 , F01K23/065 , F01K23/10 , F01K25/08 , F01K27/02
摘要： A waste heat recovery device for a marine vessel is disclosed. According to the embodiments of the present invention, the waste heat recovery device for a marine vessel includes: a heat exchanger, which recovers heat from the exhaust fumes discharged from the engine, to heat a first refrigerant under uniform pressure; a turbine which is driven by adiabatically expanding the first refrigerant heated under uniform pressure; a condenser which condenses the adiabatically expanded first refrigerant; and a heat exchanging pump which compresses the condensed first refrigerant so as to re-circulate the compressed first refrigerant to the heat exchanger.
摘要翻译：公开了一种用于船舶的废热回收装置。根据本发明的实施例，用于船舶的废热回收装置包括：热交换器，其从发动机排出的废气中回收热量，以在均匀的压力下加热第一制冷剂; 涡轮机，其通过绝热膨胀在均匀压力下加热的第一制冷剂驱动; 冷凝器，其将绝热膨胀的第一制冷剂冷凝; 以及热交换泵，其压缩冷凝的第一制冷剂，以将压缩的第一制冷剂再循环到热交换器。

7. 发明申请

US20100190310A1 Gap-filling composition with excellent shelf life by end-capping 有权
标题翻译：间隙填充组合物，通过封端具有优良的保存期限
公开(公告)号：US20100190310A1
公开(公告)日：2010-07-29
申请号：US12659908
申请日：2010-03-25
申请人： Chang Soo Woo , Hee Jae Kim , Sung Jae Lee , Sang Geun Yun , Tae Ho Kim
发明人： Chang Soo Woo , Hee Jae Kim , Sung Jae Lee , Sang Geun Yun , Tae Ho Kim
IPC分类号： H01L21/02 , C08L83/06
CPC分类号： C08L83/04 , C08G77/045 , C08G77/12 , C08G77/70
摘要： A composition with improved shelf life for filling small gaps in a semiconductor device is provided. The composition comprises an end-capped silicone polymer. The molecular weight of the end-capped silicone polymer is not varied during storage. In addition, the dissolution rate (DR) of the composition in an alkaline developing solution is maintained at a desired level during storage. That is, the composition is highly stable during storage. Therefore, the composition is suitable for use in a node separation process for the fabrication of a semiconductor capacitor.
摘要翻译：提供了一种用于填充半导体器件中的小间隙的具有改善的保质期的组合物。组合物包含封端的硅氧烷聚合物。封端硅氧烷聚合物的分子量在储存期间不变化。此外，组合物在碱性显影液中的溶解速率（DR）在储存期间保持在期望的水平。也就是说，组合物在储存期间高度稳定。因此，该组合物适用于制造半导体电容器的节点分离工艺。

8. 发明授权

US09174717B2 Intake air cooling system for a marine vessel having a turbocharger 有权
标题翻译：具有涡轮增压器的船舶的进气冷却系统
公开(公告)号：US09174717B2
公开(公告)日：2015-11-03
申请号：US13994700
申请日：2011-09-19
申请人： Eun Kyung Kim , Sung Jae Lee , Ki Jung Kim , Da Ra Heo , Gun Il Park , Jae Woong Choi
发明人： Eun Kyung Kim , Sung Jae Lee , Ki Jung Kim , Da Ra Heo , Gun Il Park , Jae Woong Choi
IPC分类号： F02B29/04 , B63H21/14 , F01K23/10 , F02B61/04 , F02B37/00 , F01P3/20
CPC分类号： B63H21/14 , F01P3/207 , F01P2060/02 , F02B29/0412 , F02B29/0443 , F02B29/0493 , F02B37/00 , F02B61/04 , Y02T10/146 , Y02T10/16
摘要： Provided is an intake air cooling system for a marine vessel having a turbocharger. The intake air cooling system for the marine vessel includes: a turbocharger which compresses the intake air introduced from the outside using a portion of the exhaust gas generated by the engine, wherein the turbocharger has a front end through which the intake air is introduced and a rear end through which the compressed intake air is supplied to the engine; a cooling part which cools at least one of the intake air compressed in the turbocharger and the exhaust gas passing through the turbocharger, wherein the cooling part includes one or more cooling units disposed along the flow of the intake air or the exhaust gas; and an absorption cooling device which receives heat from the working fluid circulated through the cooling unit.
摘要翻译：具有用于具有涡轮增压器的船舶的进气冷却系统。用于船舶的进气冷却系统包括：涡轮增压器，其利用由发动机产生的排气的一部分压缩从外部引入的进气，其中，涡轮增压器具有前端，吸入空气通过该前端引入，压缩的进气通过该后端提供给发动机; 冷却部，其冷却在所述涡轮增压器中被压缩的吸入空气中的至少一个和通过所述涡轮增压器的排气中的至少一个，其中，所述冷却部包括沿着所述进气或排气的流动配置的一个以上的冷却单元; 以及吸收冷却装置，其从通过冷却单元循环的工作流体接收热量。

9. 发明授权

US08188576B2 Compound for filling small gaps in a semiconductor device, composition including the compound, and method of fabricating a semiconductor capacitor 有权
标题翻译：用于填充半导体器件中的小间隙的化合物，包含该化合物的组合物以及制造半导体电容器的方法
公开(公告)号：US08188576B2
公开(公告)日：2012-05-29
申请号：US13038608
申请日：2011-03-02
申请人： Sung Jae Lee , Hee Jae Kim , Tae Ho Kim , Sang Geun Yun , Chang Soo Woo
发明人： Sung Jae Lee , Hee Jae Kim , Tae Ho Kim , Sang Geun Yun , Chang Soo Woo
IPC分类号： H01L23/58
CPC分类号： C08G77/04 , Y10T428/31663
摘要： A compound for filling small gaps in a semiconductor device, a composition for filling small gaps in a semiconductor device, and a method of fabricating a semiconductor capacitor, the compound including hydrolysates prepared by hydrolysis, in the presence of an acid catalyst, of compounds represented by Formulae 1, 2, and 3: [RO]3Si—[CH2]nR′ (1) wherein, in Formula 1, n is an integer from 0 to about 10, and R and R′ are each independently a hydrogen atom, a C1-C12 alkyl group, or a C6-C20 aryl group; HOOC[CH2]nR2Si—O—SiR′2[CH2]nCOOH (2) wherein, in Formula 2, each n is independently an integer from 0 to about 10, and R and R′ are each independently a C1-C12 alkyl group or a C6-C20 aryl group; and R3Si—O—X (3) wherein, in Formula 3, X is R′ or SiR′3, and R and R′ are each independently a C1-C12 alkyl group or a C6-C20 aryl group, or a polycondensate prepared by polycondensation of the hydrolysates represented by Formulae 1, 2, and 3.
摘要翻译：一种用于填充半导体器件中的小间隙的化合物，用于填充半导体器件中的小间隙的组合物以及制造半导体电容器的方法，所述化合物包括通过水解制备的水解产物，在酸催化剂存在下，表示的化合物通式1，2和3：[RO] 3Si- [CH 2] n R'（1）其中，在式1中，n为0至约10的整数，R和R'各自独立地为氢原子， C 1 -C 12烷基或C 6 -C 20芳基; HOOC [CH2] nR2Si-O-SiR'2 [CH2] nCOOH（2）其中，在式2中，每个n独立地为0至约10的整数，并且R和R'各自独立地为C 1 -C 12烷基或C 6 -C 20芳基; 和R3Si-O-X（3）其中，在式3中，X为R'或SiR'3，R和R'各自独立地为C1-C12烷基或C6-C20芳基，或缩聚物通过由式1,2和3表示的水解产物的缩聚。

10. 发明申请

US20110151640A1 COMPOUND FOR FILLING SMALL GAPS IN A SEMICONDUCTOR DEVICE, COMPOSITION INCLUDING THE COMPOUND, AND METHOD OF FABRICATING A SEMICONDUCTOR CAPACITOR 有权
标题翻译：用于在半导体器件中填充小GAPS的化合物，包括该化合物的组合物，以及制造半导体电容器的方法
公开(公告)号：US20110151640A1
公开(公告)日：2011-06-23
申请号：US13038608
申请日：2011-03-02
申请人： Sung Jae Lee , Hee Jae Kim , Tae Ho Kim , Sang Geun Yun , Chang Soo Woo
发明人： Sung Jae Lee , Hee Jae Kim , Tae Ho Kim , Sang Geun Yun , Chang Soo Woo
IPC分类号： H01L21/02 , C08G77/18 , C08L83/06 , C08L63/00 , C08K5/10 , C08K3/00 , C08K5/103 , C08K5/07
CPC分类号： C08G77/04 , Y10T428/31663
摘要： A compound for filling small gaps in a semiconductor device, a composition for filling small gaps in a semiconductor device, and a method of fabricating a semiconductor capacitor, the compound including hydrolysates prepared by hydrolysis, in the presence of an acid catalyst, of compounds represented by Formulae 1, 2, and 3: [RO]3Si—[CH2]nR′ (1) wherein, in Formula 1, n is an integer from 0 to about 10, and R and R′ are each independently a hydrogen atom, a C1-C12 alkyl group, or a C6-C20 aryl group; HOOC[CH2]nR2Si—O—SiR′2[CH2]nCOOH (2) wherein, in Formula 2, each n is independently an integer from 0 to about 10, and R and R′ are each independently a C1-C12 alkyl group or a C6-C20 aryl group; and R3Si—O—X (3) wherein, in Formula 3, X is R′ or SiR′3, and R and R′ are each independently a C1-C12 alkyl group or a C6-C20 aryl group, or a polycondensate prepared by polycondensation of the hydrolysates represented by Formulae 1, 2, and 3.
摘要翻译：一种用于填充半导体器件中的小间隙的化合物，用于填充半导体器件中的小间隙的组合物以及制造半导体电容器的方法，所述化合物包括通过水解制备的水解产物，在酸催化剂存在下，表示的化合物通式1，2和3：[RO] 3Si- [CH 2] n R'（1）其中，在式1中，n为0至约10的整数，R和R'各自独立地为氢原子， C 1 -C 12烷基或C 6 -C 20芳基; HOOC [CH2] nR2Si-O-SiR'2 [CH2] nCOOH（2）其中，在式2中，每个n独立地为0至约10的整数，并且R和R'各自独立地为C 1 -C 12烷基或C 6 -C 20芳基; 和R3Si-O-X（3）其中，在式3中，X为R'或SiR'3，R和R'各自独立地为C1-C12烷基或C6-C20芳基，或缩聚物通过由式1,2和3表示的水解产物的缩聚。

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