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1. 发明授权

US08211032B2 Cardiomechanical assessment for cardiac resynchronization therapy 有权
标题翻译：心脏再同步治疗的心脏力学评估
公开(公告)号：US08211032B2
公开(公告)日：2012-07-03
申请号：US13191253
申请日：2011-07-26
申请人： Stuart O. Schecter , Kjell Noren
发明人： Stuart O. Schecter , Kjell Noren
IPC分类号： A61B5/0452
CPC分类号： A61N1/36514 , A61N1/36578
摘要： A first lead provides therapeutic stimulation to the heart and includes a first mechanical sensor that measures physical contraction and relaxation of the heart. A controller induces delivery of therapeutic stimulation via the first lead. The controller receives signals from the first mechanical sensor indicative of the contraction and relaxation; develops a template signal that corresponds to the contraction and relaxation; and uses the template signal to modify the delivery of therapeutic stimulations. In another arrangement, a second lead, with a second mechanical sensor also provides signals to the controller indicative of contraction and relaxation. The first mechanical sensor is adapted to be positioned at the interventricular septal region of the heart, and the second mechanical sensor is adapted to be positioned in the lateral region of the left ventricle. The controller processes the signals from the first mechanical sensor and the second mechanical sensor to develop a dysynchrony index.
摘要翻译：第一个引线提供对心脏的治疗刺激，并且包括测量心脏的身体收缩和松弛的第一机械传感器。控制器通过第一引线诱导治疗性刺激。控制器从第一机械传感器接收指示收缩和松弛的信号; 开发对应于收缩和放松的模板信号; 并使用模板信号修改治疗刺激的递送。在另一种布置中，具有第二机械传感器的第二引线还向控制器提供指示收缩和松弛的信号。第一机械传感器适于定位在心脏的室间隔区域，并且第二机械传感器适于定位在左心室的侧向区域中。控制器处理来自第一机械传感器和第二机械传感器的信号以产生异步指数。

2. 发明申请

US20110306890A1 CARDIOMECHANICAL ASSESSMENT FOR CARDIAC RESYNCHRONIZATION THERAPY 有权
标题翻译：心脏康复治疗的心脏评估
公开(公告)号：US20110306890A1
公开(公告)日：2011-12-15
申请号：US13191253
申请日：2011-07-26
申请人： Stuart O. Schecter , Kjell Noren
发明人： Stuart O. Schecter , Kjell Noren
IPC分类号： A61N1/365 , A61B5/024
CPC分类号： A61N1/36514 , A61N1/36578
摘要： A first lead provides therapeutic stimulation to the heart and includes a first mechanical sensor that measures physical contraction and relaxation of the heart. A controller induces delivery of therapeutic stimulation via the first lead. The controller receives signals from the first mechanical sensor indicative of the contraction and relaxation; develops a template signal that corresponds to the contraction and relaxation; and uses the template signal to modify the delivery of therapeutic stimulations. In another arrangement, a second lead, with a second mechanical sensor also provides signals to the controller indicative of contraction and relaxation. The first mechanical sensor is adapted to be positioned at the interventricular septal region of the heart, and the second mechanical sensor is adapted to be positioned in the lateral region of the left ventricle. The controller processes the signals from the first mechanical sensor and the second mechanical sensor to develop a dysynchrony index.
摘要翻译：第一个引线提供对心脏的治疗刺激，并且包括测量心脏的身体收缩和松弛的第一机械传感器。控制器通过第一引线诱导治疗性刺激。控制器从第一机械传感器接收指示收缩和松弛的信号; 开发对应于收缩和放松的模板信号; 并使用模板信号修改治疗刺激的递送。在另一种布置中，具有第二机械传感器的第二引线还向控制器提供指示收缩和松弛的信号。第一机械传感器适于定位在心脏的室间隔区域，并且第二机械传感器适于定位在左心室的侧向区域中。控制器处理来自第一机械传感器和第二机械传感器的信号以产生异步指数。

3. 发明授权

US08014864B2 Cardiomechanical assessment for cardiac resynchronization therapy 有权
标题翻译：心脏再同步治疗的心脏力学评估
公开(公告)号：US08014864B2
公开(公告)日：2011-09-06
申请号：US12140862
申请日：2008-06-17
申请人： Stuart O. Schecter , Kjell Noren
发明人： Stuart O. Schecter , Kjell Noren
IPC分类号： A61N1/08
CPC分类号： A61N1/36514 , A61N1/36578
摘要： A first lead provides therapeutic stimulation to the heart and includes a first mechanical sensor that measures physical contraction and relaxation of the heart. A controller induces delivery of therapeutic stimulation via the first lead. The controller receives signals from the first mechanical sensor indicative of the contraction and relaxation; develops a template signal that corresponds to the contraction and relaxation; and uses the template signal to modify the delivery of therapeutic stimulations. In another arrangement, a second lead, with a second mechanical sensor also provides signals to the controller indicative of contraction and relaxation. The first mechanical sensor is adapted to be positioned at the interventricular septal region of the heart, and the second mechanical sensor is adapted to be positioned in the lateral region of the left ventricle. The controller processes the signals from the first mechanical sensor and the second mechanical sensor to develop a dysynchrony index.
摘要翻译：第一个引线提供对心脏的治疗刺激，并且包括测量心脏的身体收缩和松弛的第一机械传感器。控制器通过第一引线诱导治疗性刺激。控制器从第一机械传感器接收指示收缩和松弛的信号; 开发对应于收缩和放松的模板信号; 并使用模板信号修改治疗刺激的递送。在另一种布置中，具有第二机械传感器的第二引线还向控制器提供指示收缩和松弛的信号。第一机械传感器适于定位在心脏的室间隔区域，并且第二机械传感器适于定位在左心室的侧向区域中。控制器处理来自第一机械传感器和第二机械传感器的信号以产生异步指数。

4. 发明申请

US20090312814A1 CARDIOMECHANICAL ASSESSMENT FOR CARDIAC RESYNCHRONIZATION THERAPY 有权
标题翻译：心脏康复治疗的心脏评估
公开(公告)号：US20090312814A1
公开(公告)日：2009-12-17
申请号：US12140862
申请日：2008-06-17
申请人： Stuart O. Schecter , Kjell Noren
发明人： Stuart O. Schecter , Kjell Noren
IPC分类号： A61N1/365
CPC分类号： A61N1/36514 , A61N1/36578
摘要： A first lead provides therapeutic stimulation to the heart and includes a first mechanical sensor that measures physical contraction and relaxation of the heart. A controller induces delivery of therapeutic stimulation via the first lead. The controller receives signals from the first mechanical sensor indicative of the contraction and relaxation; develops a template signal that corresponds to the contraction and relaxation; and uses the template signal to modify the delivery of therapeutic stimulations. In another arrangement, a second lead, with a second mechanical sensor also provides signals to the controller indicative of contraction and relaxation. The first mechanical sensor is adapted to be positioned at the interventricular septal region of the heart, and the second mechanical sensor is adapted to be positioned in the lateral region of the left ventricle. The controller processes the signals from the first mechanical sensor and the second mechanical sensor to develop a dysynchrony index.
摘要翻译：第一个引线提供对心脏的治疗刺激，并且包括测量心脏的身体收缩和松弛的第一机械传感器。控制器通过第一引线诱导治疗性刺激。控制器从第一机械传感器接收指示收缩和松弛的信号; 开发对应于收缩和放松的模板信号; 并使用模板信号修改治疗刺激的递送。在另一种布置中，具有第二机械传感器的第二引线还向控制器提供指示收缩和松弛的信号。第一机械传感器适于定位在心脏的室间隔区域，并且第二机械传感器适于定位在左心室的侧向区域中。控制器处理来自第一机械传感器和第二机械传感器的信号以产生异步指数。

5. 发明授权

US08663122B2 Cardiovascular haptic handle system 有权
标题翻译：心血管触觉手柄系统
公开(公告)号：US08663122B2
公开(公告)日：2014-03-04
申请号：US13448879
申请日：2012-04-17
申请人： Stuart O. Schecter
发明人： Stuart O. Schecter
IPC分类号： A61B5/02
CPC分类号： A61B5/1102 , A61B5/0031 , A61B5/029 , A61B8/08
摘要： Cardiac tissue motion characteristics acquired by novel cardiac sensors are analyzed and processed for the derivation of physiological indices. The indices are output to a hand held local or remote volumetric haptic display and enable an operator to obtain motion related dynamic characteristics of cardiac tissues. The ability to tactually sense the motion of cardiac tissue and the affect on such motion from inserted cardiovascular instrumentation enhances the operator's performance of procedures including the positioning and placement of implanted catheters/sensors, extraction of permanently implanted leads and delivery of cardiovascular therapies. Optimal haptic rendering is achieved by using computational techniques to reconstruct the physically and perceptually relevant aspects of acquired signals and bridge the gap between the inserted catheter and operator's hand/catheter handle.
摘要翻译：分析和处理由新型心脏传感器获得的心脏组织运动特征，用于推导生理指标。指数输出到手持本地或远程体积触觉显示，并使操作者能够获得心脏组织的运动相关动态特征。从插入的心血管仪器手术感觉心脏组织的运动和对这种运动的影响的能力增强了操作者的程序性能，包括植入的导管/传感器的定位和放置，永久植入的引线的提取和心血管疗法的递送。通过使用计算技术来重建获取的信号的物理和感知相关方面并桥接插入的导管和操作者的手/导管手柄之间的间隙来实现最佳触觉渲染。

6. 发明申请

US20120239103A1 INDIVIDUALLY ADAPTED CARDIAC ELECTRO-MECHANICAL SYNCHRONIZATION THERAPY 有权
标题翻译：单独适应的心脏电子机械同步治疗
公开(公告)号：US20120239103A1
公开(公告)日：2012-09-20
申请号：US13486990
申请日：2012-06-01
申请人： Stuart O. Schecter
发明人： Stuart O. Schecter
IPC分类号： A61N1/365
CPC分类号： G06F8/4451 , A61B5/04525 , A61N1/3627 , A61N1/36521
摘要： A method of determining pacing therapy for an individual patient including determining representative electromechanical physiologic characteristics for a plurality of normal patients having a range of anatomical dimensions and developing a plurality of normal templates. Each template indicates the representative electromechanical physiologic characteristics of a group of normal patients having similar anatomical dimensions. The method can include measuring the anatomical dimensions of a dysfunctional patient, matching the dysfunctional patient with a template for normal patients having similar anatomical dimensions as the dysfunctional patient, determining the physiologic characteristics for the dysfunctional patient, determining indicated correction factors corresponding to any differences between the dysfunctional patient's physiologic characteristics and those of the matched template, and adjusting therapy delivery by any indicated correction factors to stimulate the patient in a pattern more closely matched to the physiologic characteristics of the matched template.
摘要翻译：一种确定个体患者的起搏治疗的方法，包括确定具有解剖尺寸范围的多个正常患者的代表性机电生理特征，并开发多个正常模板。每个模板指示具有相似解剖尺寸的一组正常患者的代表性机电生理特征。该方法可以包括测量功能障碍患者的解剖尺寸，使功能障碍患者与具有与功能障碍患者相似的解剖尺寸的正常患者的模板匹配，确定功能障碍患者的生理特征，确定对应于任何差异的指示的校正因子功能障碍患者的生理特征和匹配模板的生理特征，以及通过任何指示的校正因子调整治疗递送，以以与匹配模板的生理特征更接近的模式刺激患者。

7. 发明申请

US20100228103A1 MULTIFACETED IMPLANTABLE SYNCOPE MONITOR - MISM 审中-公开
标题翻译：多功能可编程同步监视器 - MISM
公开(公告)号：US20100228103A1
公开(公告)日：2010-09-09
申请号：US12398956
申请日：2009-03-05
申请人： Stuart O. Schecter
发明人： Stuart O. Schecter
IPC分类号： A61B5/00
CPC分类号： A61B5/4094 , A61B5/021 , A61B5/0402 , A61B5/0476 , A61B5/0488 , A61B5/0816 , A61B5/1116 , A61B5/1118 , A61B5/145
摘要： A multi-channel implantable syncope monitor that monitors ECG data, myopotential data, EEG data, photoplethysmography (PPG) data, and position sensor data is used to capture physiologic data about a patient who is experiencing a syncopal event. The timing of the events within the simultaneously captured physiologic data can then be used to more accurately determine potential sources of origin of the syncopal event.
摘要翻译：用于监测ECG数据的多通道植入式晕厥监测仪，离子数据，脑电图数据，光电容积描记术（PPG）数据和位置传感器数据用于捕获正在经历晕厥事件的患者的生理数据。同时捕获的生理数据中的事件的时间可以用于更准确地确定晕厥事件的潜在起源。

8. 发明授权

US07720529B1 Implantable therapeutic device control system 有权
标题翻译：植入式治疗装置控制系统
公开(公告)号：US07720529B1
公开(公告)日：2010-05-18
申请号：US11768343
申请日：2007-06-26
申请人： Stuart O. Schecter
发明人： Stuart O. Schecter
IPC分类号： A61B5/04
CPC分类号： A61N1/3622 , A61B5/053 , A61B5/7221 , A61N1/3627 , A61N1/368
摘要： A control system for an implantable cardiac therapy device, the device defining a plurality of sensing vectors including at least one impedance sensing vector and operating under a set of a plurality of variable operating parameters that define conditions for delivery of therapy and wherein the control system evaluates signal quality from the at least one impedance sensing vector and, if the quality is sufficient to discern valvular events, the control system adjusts the set of operating parameters to dynamically improve cardiac performance, including synchrony with valvular events, and if the quality is insufficient to discern valvular events, but sufficient to discern peaks, the control system adjusts the set of operating parameters to dynamically improve cardiac performance independent of valvular events, and if the quality is insufficient to discern peaks, the control system adjusts the set of operating parameters to induce cardiac performance towards a defined performance goal.
摘要翻译：一种用于可植入心脏治疗装置的控制系统，所述装置限定多个感测向量，所述感测向量包括至少一个阻抗感测向量，并且在多个可变操作参数的集合下操作，所述可变操作参数定义用于递送治疗的条件，并且其中所述控制系统评估来自至少一个阻抗感测向量的信号质量，并且如果质量足以识别瓣膜事件，则控制系统调整一组操作参数以动态改善心脏性能，包括与瓣膜事件同步，并且如果质量不足以鉴别瓣膜事件，但足以辨别峰值，控制系统调整一组操作参数，以动态改善心脏性能，独立于瓣膜事件，如果质量不足以辨别峰值，则控制系统调整一组操作参数以诱发心脏性能达到定义的性能目标。

9. 发明申请

US20120265083A1 CARDIOVASCULAR HAPTIC HANDLE SYSTEM 有权
标题翻译：心血管手术系统
公开(公告)号：US20120265083A1
公开(公告)日：2012-10-18
申请号：US13448879
申请日：2012-04-17
申请人： Stuart O. Schecter
发明人： Stuart O. Schecter
IPC分类号： A61B5/11 , A61B5/02
CPC分类号： A61B5/1102 , A61B5/0031 , A61B5/029 , A61B8/08
摘要： Cardiac tissue motion characteristics acquired by novel cardiac sensors are analyzed and processed for the derivation of physiological indices. The indices are output to a hand held local or remote volumetric haptic display and enable an operator to obtain motion related dynamic characteristics of cardiac tissues. The ability to tactually sense the motion of cardiac tissue and the affect on such motion from inserted cardiovascular instrumentation enhances the operator's performance of procedures including the positioning and placement of implanted catheters/sensors, extraction of permanently implanted leads and delivery of cardiovascular therapies. Optimal haptic rendering is achieved by using computational techniques to reconstruct the physically and perceptually relevant aspects of acquired signals and bridge the gap between the inserted catheter and operator's hand/catheter handle.
摘要翻译：分析和处理由新型心脏传感器获得的心脏组织运动特征，用于推导生理指标。指数输出到手持本地或远程体积触觉显示，并使操作者能够获得心脏组织的运动相关动态特征。从插入的心血管仪器手术感觉心脏组织的运动和对这种运动的影响的能力增强了操作者的程序性能，包括植入的导管/传感器的定位和放置，永久植入的引线的提取和心血管疗法的递送。通过使用计算技术来重建获取的信号的物理和感知相关方面并桥接插入的导管和操作者的手/导管手柄之间的间隙来实现最佳触觉渲染。

10. 发明授权

US07751889B1 Closed loop programming for individual adjustment of electro-mechanical synchrony 失效
标题翻译：闭环编程，用于单机调节机电同步
公开(公告)号：US07751889B1
公开(公告)日：2010-07-06
申请号：US11734117
申请日：2007-04-11
申请人： Stuart O. Schecter
发明人： Stuart O. Schecter
IPC分类号： A61N1/365
CPC分类号： A61N1/3627 , A61B5/0031 , A61B5/0452 , A61B5/05 , A61B5/7285 , A61N1/36521 , A61N1/36585 , A61N1/3682 , A61N1/37247
摘要： An implantable therapy system including implantable stimulation and control components. The implantable components operate under a set of variable parameters that can be adjusted for improved performance for an individual patient. The implantable components are adapted to self-evaluate the patients physiologic performance and autonomously adjust an existing set of parameters to improve performance throughout an implantation period without requiring intervention of a clinician, for example with a physicians programmer. The implantable components can compare a patient's exhibited activity to a desired template of that activity to determine when adjustments are indicated. The template can be based on observations of one or more third parties exhibiting normal activity. The implantable components can adjust the operating parameters to improve synchrony of multiple heart chambers and/or to increase a peak contractility.
摘要翻译：一种植入式治疗系统，包括可植入的刺激和控制组件。可植入组件在一组可变参数下操作，可以针对单个患者进行调整以改善性能。可植入组件适于自我评估患者的生理表现并自主地调整现有参数集以改善整个植入期间的性能，而不需要例如与医生程序员的临床医生的干预。可植入组件可以将患者的展示活动与该活动的期望模板进行比较，以确定何时显示调整。模板可以基于一个或多个表现正常活动的第三方的观察结果。可植入部件可以调整操作参数以改善多个心室的同步和/或增加峰值收缩性。

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